Fight Aging! Newsletter, February 26th 2024
In conclusion, mTORC1 signaling contributes to the ISC fate decision, enabling regional control of intestinal cell differentiation in response to nutrition.
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Reviewing the Development of Senotherapeutics to Treat Aging
https://www.fightaging.org/archives/2024/02/reviewing-the-development-of-senotherapeutics-to-treat-aging/
Senescent cells accumulate with age and contribute meaningfully to chronic inflammation and degenerative aging. Destroying these cells produces rapid and sizable reversal of age-related diseases in mice, demonstrating that the presence of senescence cells ...
Source: Fight Aging! - February 25, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
An Update on Kimer Med, Improving on the DRACO Antiviral Technology and Moving Towards the Clinic
The state of anti-viral therapies isn't that great, all things considered. Technology has not yet advanced to the point at which a viral infection can be simply shut down, as is the case for near all bacterial infections. The present anti-viral drugs are either vaccines (useful!) or merely shift the odds somewhat by interfering in some part of the viral life cycle, but nowhere near as effectively as desired. Many persistent viral infections are thought to contribute meaningfully to forms of age-related dysfunction, and there is too little that can be done about that at the present time.
This landscape is one of the ...
Source: Fight Aging! - February 23, 2024 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
There ’ s no place for “ benevolent deception ” in obstetrics
When I was 36 weeks pregnant with my second child, Anna, my obstetrician noted that my fetus had a disproportionately small head, or microcephaly—a condition now commonly known because of its association with the Zika virus. “We’ll just have to wait and see,” he said, meaning we’ll look for answers if the baby is affected
Read more…
There’s no place for “benevolent deception” in obstetrics originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 27, 2023 Category: General Medicine Authors: Megan Nix Tags: Conditions OB/GYN Source Type: blogs
Some Like It Hot! A Century-Old Disease on Our Southern Shores
By MIKE MAGEE
Naomi Orestes PhD, Professor of the History of Science at Harvard, didn’t mince words as she placed our predicament in context when she said, “If you know your Greek tragedies you know power, hubris, and tragedy go hand in hand. If we don’t address the harmful aspects of human activities, most obviously disruptive climate change, we are headed for tragedy.”
At the time, as a member of the Anthropocene Workgroup, she and a group of international climate scientists were focused on defining and measuring nine “planetary boundaries,” environmental indicators of planetary health. At...
Source: The Health Care Blog - October 30, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Avian Flu Climate Change Pandemic Sea level change Yellow Fever Source Type: blogs
Peptoid Oligomers Target Viral Membranes
Researchers at New York University have developed a new method to target many viruses that cause disease. For viruses with a lipid membrane, which includes many that commonly cause disease, this new technique could prove to be fatal. By targeting the lipid membrane, the approach may circumvent the treatment resistance that arises when viruses mutate to alter their surface proteins, which are the most common targets for conventional anti-viral drugs. This new approach is based on a synthetic version of antimicrobial peptides, which are naturally produced by our immune system and can target pathogens such as bacteria and vir...
Source: Medgadget - August 30, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Public Health Source Type: blogs
Environmental Health Surveillance Powered by GIS Technology Enhances Public Health Efforts at San Bernardino County
San Bernadino Public Health knows that monitoring the mosquito population benefits community health directly. This is why the public health team is tracking mosquitos breeding areas and leveraging GIS technology to better coordinate mosquito control efforts in order to prevent the spread of disease.
Healthcare IT Today spoke with Serene Ong – Geographic Information Systems Analyst, Andrew Mackey – Statistical Analyst, and Anthony Arce – Research Analyst at San Bernardino County Department of Public Health (SBCDPH) to find out more.
Mosquito Surveillance
Mosquito Surveillance is used to monitor mosquito po...
Source: EMR and HIPAA - August 1, 2023 Category: Information Technology Authors: Colin Hung Tags: Analytics/Big Data Health IT Company Healthcare IT Andrew Mackey Anthony Arce ArcGIS esri GIS technology Mosquito Surveillance Public Health San Bernardino County San Bernardino County Department of Public Health SBCDPH Serene On Source Type: blogs
The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
September 08, 2022 Edition-----In the US we are seeing the outcomes of Climate Change really of and running with droughts and fires etc. Biden amped up the partisan divide with a fiery anti-Republican speech!In Russia the last leader of Soviet Russia died.In the UK we have a new PM while in Europe the energy crisis is just getting worse.In OZ we have survived the Jobs and Skills Summit with 36 prearranged outcomes. Stage management +++ in action. The GP crisis is not being addressed fully and worries regarding the Global Economy - esp. China - worsen.-----Major Issues.-----https://www.afr.com/work-and-careers/educati...
Source: Australian Health Information Technology - September 8, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fighting Viruses with Viruses
by Gertrud U. Rey Errors during viral replication can give rise to shortened and/or rearranged genomic sequences known as “defective viral genomes” (DVGs). Because DVGs often lack critical elements needed for replication and formation of new viral particles, virions containing DVGs can only complete a replication cycle if they co-infect a cell together with respective […] (Source: virology blog)
Source: virology blog - May 5, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey antiviral Chikungunya virus defective viral genomes dengue virus DVGs mosquitoes zika virus Source Type: blogs
Innovation, mRNA, and Public Policy
Chris EdwardsThe main weapons against COVID-19 are the vaccines developed by Moderna and BioNTech after a decade of their research into mRNA technologies. That research was supported by more than $3 billion of private angel investment and venture capital.Democrats and Republicans both support medical research funding, and Republicans tout the Trump administration ’s Operation Warp Speed. But governments were not the key to mRNA development. Instead, we can thank the leaders and scientists at Moderna and BioNTech and the suppliers of private capital to them, as I discusshere andhere.TheWall Street Journal ’s A...
Source: Cato-at-liberty - December 6, 2021 Category: American Health Authors: Chris Edwards Source Type: blogs
Multistep Lateral Flow Devices Perform Advanced Assays
Researchers at Georgia Tech have developed a lateral flow test platform that can perform advanced assays that would otherwise require a laboratory. By controlling the flow of liquid through the lateral flow test, the research team designed it so that it can perform advanced multistep assays that do not require sophisticated lab equipment and significant periods of time. So far, they have designed advanced dipstick tests that can detect both COVID-19 and influenza simultaneously, and others that can perform immunoassays to detect Zika virus, HIV, hepatitis B virus, or malaria.
Lateral flow assays, otherwise ...
Source: Medgadget - November 10, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Medicine Pathology Public Health georgiatech Source Type: blogs
Electrochemical Device Detects SARS ‑CoV‑2 Spike Protein in 1 Second
Researchers at the University of Florida and the National Chiao Tung University in Taiwan have developed a microfluidic device that can detect the SARS‑CoV‑2 spike protein in a saliva sample within one second. The electrochemical device employs antibodies against the spike protein to detect the virus, and could allow for ultra-rapid COVID-19 testing.
Testing is still a cornerstone in our fight against COVID-19. While the pandemic has calmed in certain regions of the world, others are still badly affected, and it will be a long time before robust testing regimes are no longer required. The current gold standard ...
Source: Medgadget - May 21, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Pathology Public Health Source Type: blogs
American Industrial Policy in Action
Scott LincicomeIn case you haven't noticed, U.S. industrial policy is having (yet another) moment. Armed with the latest data and cross-country comparisons, a large and bipartisan cadre of industrial policy advocates in Washington are eager to shovel billions of taxpayer dollars into the open arms of American manufacturers of "essential goods" and "critical technologies." The risks (China, pandemics, whatever), so the theory goes, greatly outweigh any harms that a few, scattered industrial policy failures might cause along the way, so whynot just throw money at the (perceived) problems? These advocates, however, rarely ack...
Source: Cato-at-liberty - April 8, 2021 Category: American Health Authors: Scott Lincicome Source Type: blogs
Overinterpreting Computational Models of Decision-Making
Bell (1985)Can a set of equations predict and quantify complex emotions resulting from financial decisions made in an uncertain environment? Aninfluential paper by David E. Bell considered the implications of disappointment, a psychological reaction caused by comparing an actual outcome to a more optimistic expected outcome, as in playing the lottery. Equations for regret, disappointment, elation, and satisfaction have been incorporated into economic models of financial decision-making (e.g., variants ofprospect theory).Financial choices comprise one critical aspect of decision-making in our daily lives. There are so many ...
Source: The Neurocritic - March 31, 2021 Category: Neuroscience Authors: The Neurocritic Source Type: blogs
Correlative Adventures with COVID
By ANISH KOKA
“The patient in room 1 should be a quick one, its an addon, they just need a prescription for ivermectin”
I’m a bit puzzled by this sentence from my assistant doing his best to help me through a very busy day in the clinic that I’m already behind in. I walk into the room, a script pad stuffed into my hand as I enter the room, to meet a very nice couple. The wife sits patiently with hands crossed on the exam table.
“So, you’re here for Ivermectin?”, I ask.
Why yes, a trip to Texas is planned.. COVID is in the air, the internet, and some important people who have ‘inside ...
Source: The Health Care Blog - March 5, 2021 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy Anish Koka COVID vaccine COVID-19 vaccine Ivermectin Source Type: blogs
