Lab-on-paper strip: Small, inexpensive platform for diagnosing tropical fevers

(GIST (Gwangju Institute of Science and Technology)) Dengue, zika, and chikungunya viruses are transmitted by mosquitoes and cause tropical fevers with similar symptoms, making accurate diagnosis complicated. Now, researchers from Gwangju Institute of Science and Technology in Korea have developed a simple and low-cost diagnostic platform--a lab-on-paper strip--that can readily detect the specific RNA of these viruses from a small blood sample.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

Related Links:

da HR Abstract The Northeast of Brazil has experienced a triple epidemic, with the simultaneous circulation of dengue virus (DENV), chikungunya virus (CHIKV) and Zika virus (ZIKV), which may have contributed to the observed increase across this region of atypical forms of disease and deaths. In view of this fact, non-congenital neurological disorders related to arboviruses were compared with other etiologies, mortality and survival rates of patients admitted to referral neurology hospitals in Pernambuco State, Northeast Brazil, from 2015 to 2018. Blood and cerebrospinal fluid samples were collected and tested usin...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
CONCLUSIONS: These rubber residues, usually located nearby human populations, represent suitable breeding sites for arboviruses vectors such as dengue, chikungunya, Zika, and West Nile. PMID: 33030829 [PubMed - as supplied by publisher]
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Tags: Biomedica Source Type: research
Current urban vector control strategies have failed to contain dengue epidemics and to prevent the global expansion of Aedes-borne viruses (ABVs: dengue, chikungunya, Zika). Part of the challenge in sustaining ef...
Source: Trials - Category: General Medicine Authors: Tags: Study protocol Source Type: research
AbstractBackgroundCurrent urban vector control strategies have failed to contain dengue epidemics and to prevent the global expansion ofAedes-borne viruses (ABVs: dengue, chikungunya, Zika). Part of the challenge in sustaining effective ABV control emerges from the paucity of evidence regarding the epidemiological impact of anyAedes control method. A strategy for which there is limited epidemiological evidence is targeted indoor residual spraying (TIRS). TIRS is a modification of classic malaria indoor residual spraying that accounts forAedes aegypti resting behavior by applying residual insecticides on exposed lower sections of walls (
Source: Trials - Category: Research Source Type: clinical trials
D. Frentiu Dengue, chikungunya and Zika viruses share similar disease features, rendering them difficult to distinguish clinically. Incapacitating arthralgia/arthritis is a specific manifestation associated with chikungunya virus infection. However, the profile of arthralgia/arthritis in Zika virus (ZIKV) cases has not been well characterized. Articles were extracted from PubMed and Scopus databases reporting original data from patients with arthralgia/arthritis, according to the Cochrane Collaboration. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, 137 articles reporting ZIKV...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Abstract Genus Flavivirus, which includes 53 virus species, is the leading cause of arthropod-borne diseases in humans. Diagnosis of these viral diseases is complicated by their overlapping epidemiology and clinical manifestations, and the fact that cross-reactive antibody responses are frequently elicited by individuals in response to infection. We developed a bead-based immunoassay to concomitantly profile the isotype and subclass of antibody responses (five isotypes and four subclasses) in parallel with specificity against multiple antigens. Our panel included 22 envelope (E) and non-structural 1 (NS1) proteins...
Source: Journal of Immunological Methods - Category: Allergy & Immunology Authors: Tags: J Immunol Methods Source Type: research
by Chlo é Bohers, Laurence Mousson, Yoann Madec, Marie Vazeille, Adel Rhim, Youmna M’ghirbi, Ali Bouattour, Anna-Bella Failloux The mosquitoAedes albopictus was detected for the first time in Tunisia in 2018. With its establishment in the capital city of Tunis, local health authorities fear the introduction of new human arboviral diseases, like what happened in Europe with unexpected local cases of chikungunya, dengue and Zika. Even though this mosquito is competent to transmit the arboviruses mentioned above, the transmission level will vary depending on the couple, mosquito population and virus genotype. He...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
any Usutu virus (USUV), a mosquito-borne zoonotic flavivirus discovered in South Africa in 1959, has spread to many European countries over the last 20 years. The virus is currently a major concern for animal health due to its expanding host range and the growing number of avian mass mortality events. Although human infections with USUV are often asymptomatic, they are occasionally accompanied by neurological complications reminiscent of those due to West Nile virus (another flavivirus closely related to USUV). Whilst USUV actually appears less threatening than some other emergent arboviruses, the lessons learned from ...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
by Pie M üller, Lukas Engeler, Laura Vavassori, Tobias Suter, Valeria Guidi, Martin Gschwind, Mauro Tonolla, Eleonora Flacio Over the past three decades, Europe has witnessed an increased spread of invasive aedine mosquito species, most notablyAedes albopictus, a key vector of chikungunya, dengue and Zika virus. While its distribution in southern Europe is well documented, its dispersal modes across the Alps remain poorly investigated, preventing a projection of future scenarios beyond its current range in order to target mosquito control. To monitor the presence and frequency of invasiveAedes mosquitoes across and b...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Conclusions: From all the circulating mediators measured, we detected differences of IL-10, TNF- α, and CCL2/MCP-1 between arbovirus groups. We hypothesize that CXC10/IP-10, CCL2/MCP-1, and MIF in the CHIKV-infected group could regulate the CHIKV viral load, while CXC10/IP-10, CCL2/MCP-1, and TNF-α in DENV/ZIKV, and CHIKV/ZIKV groups, could regulate ZIKV viral load.Intervirology
Source: Intervirology - Category: Virology Source Type: research
More News: Chikungunya | Dengue Fever | Infectious Diseases | Science | Zika Virus