Transgenic line for characterizing GABA-receptor expression to study the neural basis of olfaction in the yellow-fever mosquito
The mosquito Aedes aegypti is an important vector of diseases including dengue, Zika, chikungunya, and yellow fever. Olfaction is a critical modality for mosquitoes enabling them to locate hosts, sources of nectar, and sites for oviposition. GABA is an essential neurotransmitter in olfactory processing in the insect brain, including the primary olfactory center, the antennal lobe. Previous work with Ae. aegypti has suggested that antennal lobe inhibition via GABA may be involved in the processing of odors. However, little is known about GABA receptor expression in the mosquito brain, or how they may be involved in odor att...
Source: Frontiers in Physiology - March 28, 2024 Category: Physiology Source Type: research

Viral Infections, Are They a Trigger and Risk Factor of Alzheimer's Disease?
Pathogens. 2024 Mar 8;13(3):240. doi: 10.3390/pathogens13030240.ABSTRACTAlzheimer's Disease (AD), a progressive and debilitating condition, is reported to be the most common type of dementia, with at least 55 million people believed to be currently affected. Many causation hypotheses of AD exist, yet the intriguing link between viral infection and its possible contribution to the known etiology of AD has become an attractive focal point of research for the field and a challenging study task. In this review, we will explore the historical perspective and milestones that led the field to investigate the viral connection to A...
Source: Herpes - March 27, 2024 Category: Infectious Diseases Authors: Meagan D Rippee-Brooks Wenzhe Wu Jianli Dong Miguel Pappolla Xiang Fang Xiaoyong Bao Source Type: research

Long-Acting Reversible Contraception Use and Unmet Desire among Patients After the Zika Contraception Access Network Program in Puerto Rico
To describe unmet desire for long-acting reversible contraception (LARC) after the Zika Contraception Access Network (Z-CAN) in Puerto Rico during the 2016-2017 Zika outbreak. (Source: Contraception)
Source: Contraception - March 26, 2024 Category: OBGYN Authors: Andrea Stewart, Lisa Romero, Katherine Kortsmit, Stacey Hurst, Rachel Powell, Eva Lathrop, Maura K. Whiteman, Lauren B. Zapata Tags: Brief Research Article Source Type: research

WSV2023 - The second meeting of the world society for virology: One health - One world - One virology
Discussions further explored SARS-CoV-2 RNA replicons as vaccine candidates, SARS-CoV-2 in humans and animals, and the significance of plant viruses in the 'One Health' paradigm. The presence of the presidents from three virology societies, namely the American, Indian, and Korean Societies for Virology, highlighted the event's significance. Additionally, past president of the American Society for Virology (ASV), formally declared the partnership between ASV and WSV during the conference.PMID:38527382 | DOI:10.1016/j.virol.2024.110049 (Source: Virology)
Source: Virology - March 25, 2024 Category: Virology Authors: Ahmed S Abdel-Moneim Modra Murovska Maria S öderlund-Venermo Vikram N Vakharia William C Wilson Douglas P Gladue Matthew D Moore Covadonga Alonso Sayed F Abdelwahab Marietjie Venter Yashpal S Malik Shi Zhengli Shailendra K Saxena Anupam Varma Richard J K Source Type: research

WSV2023 - The second meeting of the world society for virology: One health - One world - One virology
Discussions further explored SARS-CoV-2 RNA replicons as vaccine candidates, SARS-CoV-2 in humans and animals, and the significance of plant viruses in the 'One Health' paradigm. The presence of the presidents from three virology societies, namely the American, Indian, and Korean Societies for Virology, highlighted the event's significance. Additionally, past president of the American Society for Virology (ASV), formally declared the partnership between ASV and WSV during the conference.PMID:38527382 | DOI:10.1016/j.virol.2024.110049 (Source: Virology)
Source: Virology - March 25, 2024 Category: Virology Authors: Ahmed S Abdel-Moneim Modra Murovska Maria S öderlund-Venermo Vikram N Vakharia William C Wilson Douglas P Gladue Matthew D Moore Covadonga Alonso Sayed F Abdelwahab Marietjie Venter Yashpal S Malik Shi Zhengli Shailendra K Saxena Anupam Varma Richard J K Source Type: research

Extensive variation and strain-specificity in dengue virus susceptibility among African < i > Aedes aegypti < /i > populations
by St éphanie Dabo, Annabelle Henrion-Lacritick, Alicia Lecuyer, Davy Jiolle, Christophe Paupy, Diego Ayala, Silvânia da Veiga Leal, Athanase Badolo, Anubis Vega-Rúa, Massamba Sylla, Jewelna Akorli, Sampson Otoo, Joel Lutomiah, Rosemary Sang, John-Paul Mutebi, Maria-Carla Saleh, Noah H. Rose, Carolyn S . McBride, Louis Lambrechts African populations of the mosquitoAedes aegypti are usually considered less susceptible to infection by human-pathogenic flaviviruses than globally invasive populations found outside Africa. Although this contrast has been well documented for Zika virus (ZIKV), it is unclear to what extent it...
Source: PLoS Neglected Tropical Diseases - March 25, 2024 Category: Tropical Medicine Authors: St éphanie Dabo Source Type: research

Assessing vulnerability for future Zika virus outbreaks using seroprevalence data and environmental suitability maps
by Yannik Roell, Laura Pezzi, Anyela Lozano-Parra, Daniel Olson, Jane Messina, Talia Quandelacy, Jan Felix Drexler, Oliver Brady, Morteza Karimzadeh, Thomas Jaenisch The 2015 –17 Zika virus (ZIKV) epidemic in the Americas subsided faster than expected and evolving population immunity was postulated to be the main reason. Herd immunization is suggested to occur around 60–70% seroprevalence, depending on demographic density and climate suitability. However, herd immuni ty was only documented for a few cities in South America, meaning a substantial portion of the population might still be vulnerable to a future Zika viru...
Source: PLoS Neglected Tropical Diseases - March 22, 2024 Category: Tropical Medicine Authors: Yannik Roell Source Type: research

Ophthalmologic Findings in a Premature Infant leading to a Zika Diagnosis during the COVID-19 Pandemic: A Case Report
We report on the first case of congenital Zika syndrome to be identified during the COVID-19 pandemic in Puerto Rico. The Zika virus (ZIKV) infection was first seen in Puerto Rico in December 2015. It is a flavivirus with vertical transmission, spreading from infected mothers to their fetuses and having a broad spectrum of clinical manifestations, of which microcephaly is the most worrisome. In Puerto Rico, routine ZIKV screening during pregnancy was implemented in October 2016. However, this practice has become less frequent over time. Nevertheless, the transmission of ZIKV continues, so it is important to ensure routine ...
Source: Puerto Rico Health Sciences Journal - March 21, 2024 Category: International Medicine & Public Health Authors: Jessica M Rosario-Falero Gabriella P Morantes-Betancourt Norma Claudio Ra úl Pérez Zayhara Reyes-Bou Source Type: research

Perceptions of the Zika Virus, Contraceptive Access, and Motivation to Participate in the Zika Contraception Access Network Program: Qualitative Analysis of Focusgroup Discussions with Puerto Rican Women
CONCLUSION: Focus groups can be used to understand women's knowledge of the Zika virus, barriers and facilitators to contraception access, and motivations for participation in the Z-CAN program.PMID:38512761 (Source: Puerto Rico Health Sciences Journal)
Source: Puerto Rico Health Sciences Journal - March 21, 2024 Category: International Medicine & Public Health Authors: Lisa Romero Edna Acosta-P érez Hailey Bednar Stacey Hurst Lauren B Zapata Samaris Vega-Torres Rachel Powell Eva Lathrop Source Type: research

Viral infections in pregnancy and impact on offspring neurodevelopment: mechanisms and lessons learned
Pediatr Res. 2024 Mar 20. doi: 10.1038/s41390-024-03145-z. Online ahead of print.ABSTRACTPregnant individuals with viral illness may experience significant morbidity and have higher rates of pregnancy and neonatal complications. With the growing number of viral infections and new viral pandemics, it is important to examine the effects of infection during pregnancy on both the gestational parent and the offspring. Febrile illness and inflammation during pregnancy are correlated with risk for autism, attention deficit/hyperactivity disorder, and developmental delay in the offspring in human and animal models. Historical vira...
Source: Pediatric Research - March 21, 2024 Category: Pediatrics Authors: Emma F Yates Sarah B Mulkey Source Type: research

Ophthalmologic Findings in a Premature Infant leading to a Zika Diagnosis during the COVID-19 Pandemic: A Case Report
We report on the first case of congenital Zika syndrome to be identified during the COVID-19 pandemic in Puerto Rico. The Zika virus (ZIKV) infection was first seen in Puerto Rico in December 2015. It is a flavivirus with vertical transmission, spreading from infected mothers to their fetuses and having a broad spectrum of clinical manifestations, of which microcephaly is the most worrisome. In Puerto Rico, routine ZIKV screening during pregnancy was implemented in October 2016. However, this practice has become less frequent over time. Nevertheless, the transmission of ZIKV continues, so it is important to ensure routine ...
Source: Puerto Rico Health Sciences Journal - March 21, 2024 Category: International Medicine & Public Health Authors: Jessica M Rosario-Falero Gabriella P Morantes-Betancourt Norma Claudio Ra úl Pérez Zayhara Reyes-Bou Source Type: research

Perceptions of the Zika Virus, Contraceptive Access, and Motivation to Participate in the Zika Contraception Access Network Program: Qualitative Analysis of Focusgroup Discussions with Puerto Rican Women
CONCLUSION: Focus groups can be used to understand women's knowledge of the Zika virus, barriers and facilitators to contraception access, and motivations for participation in the Z-CAN program.PMID:38512761 (Source: Puerto Rico Health Sciences Journal)
Source: Puerto Rico Health Sciences Journal - March 21, 2024 Category: International Medicine & Public Health Authors: Lisa Romero Edna Acosta-P érez Hailey Bednar Stacey Hurst Lauren B Zapata Samaris Vega-Torres Rachel Powell Eva Lathrop Source Type: research

Ophthalmologic Findings in a Premature Infant leading to a Zika Diagnosis during the COVID-19 Pandemic: A Case Report
We report on the first case of congenital Zika syndrome to be identified during the COVID-19 pandemic in Puerto Rico. The Zika virus (ZIKV) infection was first seen in Puerto Rico in December 2015. It is a flavivirus with vertical transmission, spreading from infected mothers to their fetuses and having a broad spectrum of clinical manifestations, of which microcephaly is the most worrisome. In Puerto Rico, routine ZIKV screening during pregnancy was implemented in October 2016. However, this practice has become less frequent over time. Nevertheless, the transmission of ZIKV continues, so it is important to ensure routine ...
Source: Puerto Rico Health Sciences Journal - March 21, 2024 Category: International Medicine & Public Health Authors: Jessica M Rosario-Falero Gabriella P Morantes-Betancourt Norma Claudio Ra úl Pérez Zayhara Reyes-Bou Source Type: research

Perceptions of the Zika Virus, Contraceptive Access, and Motivation to Participate in the Zika Contraception Access Network Program: Qualitative Analysis of Focusgroup Discussions with Puerto Rican Women
CONCLUSION: Focus groups can be used to understand women's knowledge of the Zika virus, barriers and facilitators to contraception access, and motivations for participation in the Z-CAN program.PMID:38512761 (Source: Puerto Rico Health Sciences Journal)
Source: Puerto Rico Health Sciences Journal - March 21, 2024 Category: International Medicine & Public Health Authors: Lisa Romero Edna Acosta-P érez Hailey Bednar Stacey Hurst Lauren B Zapata Samaris Vega-Torres Rachel Powell Eva Lathrop Source Type: research

Ophthalmologic Findings in a Premature Infant leading to a Zika Diagnosis during the COVID-19 Pandemic: A Case Report
We report on the first case of congenital Zika syndrome to be identified during the COVID-19 pandemic in Puerto Rico. The Zika virus (ZIKV) infection was first seen in Puerto Rico in December 2015. It is a flavivirus with vertical transmission, spreading from infected mothers to their fetuses and having a broad spectrum of clinical manifestations, of which microcephaly is the most worrisome. In Puerto Rico, routine ZIKV screening during pregnancy was implemented in October 2016. However, this practice has become less frequent over time. Nevertheless, the transmission of ZIKV continues, so it is important to ensure routine ...
Source: Puerto Rico Health Sciences Journal - March 21, 2024 Category: International Medicine & Public Health Authors: Jessica M Rosario-Falero Gabriella P Morantes-Betancourt Norma Claudio Ra úl Pérez Zayhara Reyes-Bou Source Type: research