Computational approaches in discovery and development of therapeutic and prophylactic agents for viral diseases
Curr Top Med Chem. 2022 Oct 19. doi: 10.2174/1568026623666221019110334. Online ahead of print.ABSTRACTOver the last two decades computational technologies have always played a crucial role in anti-viral drug development. Whenever a virus spreads and becomes a threat to global health it brings along the challenge to develop new therapeutics and prophylactics. Computational drug and vaccine discovery have evolved at a breakneck pace over the years. Some interesting examples of computational drug discovery are anti-AIDS drugs, where HIV protease and reverse transcriptase have been targeted by agents developed using computatio...
Source: Topics in HIV Medicine - October 24, 2022 Category: Infectious Diseases Authors: Anand Gaurav Neetu Agrawal Mayasah Al-Nema Vertika Gautam Source Type: research
Computational approaches in discovery and development of therapeutic and prophylactic agents for viral diseases
Curr Top Med Chem. 2022 Oct 19. doi: 10.2174/1568026623666221019110334. Online ahead of print.ABSTRACTOver the last two decades computational technologies have always played a crucial role in anti-viral drug development. Whenever a virus spreads and becomes a threat to global health it brings along the challenge to develop new therapeutics and prophylactics. Computational drug and vaccine discovery have evolved at a breakneck pace over the years. Some interesting examples of computational drug discovery are anti-AIDS drugs, where HIV protease and reverse transcriptase have been targeted by agents developed using computatio...
Source: Current Topics in Medicinal Chemistry - October 24, 2022 Category: Chemistry Authors: Anand Gaurav Neetu Agrawal Mayasah Al-Nema Vertika Gautam Source Type: research
Computational approaches in discovery and development of therapeutic and prophylactic agents for viral diseases
Curr Top Med Chem. 2022 Oct 19. doi: 10.2174/1568026623666221019110334. Online ahead of print.ABSTRACTOver the last two decades computational technologies have always played a crucial role in anti-viral drug development. Whenever a virus spreads and becomes a threat to global health it brings along the challenge to develop new therapeutics and prophylactics. Computational drug and vaccine discovery have evolved at a breakneck pace over the years. Some interesting examples of computational drug discovery are anti-AIDS drugs, where HIV protease and reverse transcriptase have been targeted by agents developed using computatio...
Source: Topics in HIV Medicine - October 24, 2022 Category: Infectious Diseases Authors: Anand Gaurav Neetu Agrawal Mayasah Al-Nema Vertika Gautam Source Type: research
Computational approaches in discovery and development of therapeutic and prophylactic agents for viral diseases
Curr Top Med Chem. 2022 Oct 19. doi: 10.2174/1568026623666221019110334. Online ahead of print.ABSTRACTOver the last two decades computational technologies have always played a crucial role in anti-viral drug development. Whenever a virus spreads and becomes a threat to global health it brings along the challenge to develop new therapeutics and prophylactics. Computational drug and vaccine discovery have evolved at a breakneck pace over the years. Some interesting examples of computational drug discovery are anti-AIDS drugs, where HIV protease and reverse transcriptase have been targeted by agents developed using computatio...
Source: Topics in HIV Medicine - October 24, 2022 Category: Infectious Diseases Authors: Anand Gaurav Neetu Agrawal Mayasah Al-Nema Vertika Gautam Source Type: research
IJERPH, Vol. 19, Pages 13724: Analysis of the Number and Type of Vaccinations Performed among Polish Soldiers in 2018 & ndash;2021
IJERPH, Vol. 19, Pages 13724: Analysis of the Number and Type of Vaccinations Performed among Polish Soldiers in 2018–2021
International Journal of Environmental Research and Public Health doi: 10.3390/ijerph192113724
Authors:
Magdalena Zawadzka
Ewelina Ejchman-Pac
Vaccination is a very common topic, but it is rarely raised or discussed with respect to military members. Soldiers are one of the main professional groups to be immunized on a regular basis. The military actively participates in research on new vaccine preparations. This paper presents data from 2018–2021 on vaccination among P...
Source: International Journal of Environmental Research and Public Health - October 22, 2022 Category: Environmental Health Authors: Magdalena Zawadzka Ewelina Ejchman-Pac Tags: Article Source Type: research
Yellow fever outbreak in Kenya: A review
Ann Med Surg (Lond). 2022 Sep 1;82:104537. doi: 10.1016/j.amsu.2022.104537. eCollection 2022 Oct.ABSTRACTYellow fever (YF) is a viral acute hemorrhagic illness caused by infected mosquitoes of the flavivirus family. The first yellow fever outbreak in Kenya was in 1992. Similar outbreaks were recorded in the western part of the country in 1993, 1995, and 2011, particularly in the Rift Valley province of Kenya. In early 2022, the viral acute illness resurfaced and hit Kenya. On January 12, 2022, the first case was discovered, with over 14 patients suffering from fever, jaundice, and joint and muscle pains. On March 4, 2022, ...
Source: Annals of Medicine - October 21, 2022 Category: Internal Medicine Authors: Olivier Uwishema Stanley Chinedu Eneh Anyike Goodness Chiburoma Wael Atif Fadl Elhassan Adeniji Abdur-Rahman Adekunle Martin Sagide Rogose ElShimaa Zaki Aymar Akilimali Helen Onyeaka Source Type: research
Lassa Virus Countermeasures
Curr Top Microbiol Immunol. 2022 Oct 18. doi: 10.1007/82_2022_261. Online ahead of print.ABSTRACTLassa Fever (LF) is a viral hemorrhagic fever endemic in West Africa. LF begins with flu-like symptoms that are difficult to distinguish from other common endemic diseases such as malaria, dengue, and yellow fever making it hard to diagnose clinically. Availability of a rapid diagnostic test and other serological and molecular assays facilitates accurate diagnosis of LF. Lassa virus therapeutics are currently in different stages of preclinical development. Arevirumab, a cocktail of monoclonal antibodies, demonstrates a great sa...
Source: Current Topics in Microbiology and Immunology - October 17, 2022 Category: Microbiology Authors: Lilia I Melnik Source Type: research
