Pneumococcal conjugate vaccination schedules in infants —acquisition, immunogenicity, and pneumococcal conjugate and yellow fever vaccine co-administration study: statistical analysis plan
We describe the approach to analyses and how we will account for the effect of clustering. Defining the SAP prior to the conduct of analysis will avoid bias in analyses that may arise from prior knowledge of trial findings.Trial registrationISRCTN, ISRCTN7282161328. Registered on 28 November 2019.https://www.isrctn.com/ISRCTN72821613.Protocol: MRCG SCC number 1670, LSHTM Ref 17683.Current protocol version: 6.0, 24 May 2021.Version: 1.0 (5 April 2023); SAP revisions —none. (Source: Trials)
Source: Trials - March 26, 2024 Category: Research Source Type: clinical trials

A Study on the Safety, Reactogenicity, and Immune Response to the GVGH iNTS-GMMA Vaccine Against Invasive Nontyphoidal Salmonella in Adults, Children, and Infants
Conditions: Salmonella Infections Interventions: Biological: Measles and Rubella vaccine; Biological: Yellow Fever vaccine; Biological: Pentavalent vaccine; Biological: Pneumococcal vaccine; Biological: Inactivated polio vaccine; Biological: iNTS-GMMA Dose C; Biological: iNTS-GMMA Dose B; Biological: iNTS-GMMA Dose A; Biological: MenACWY; Combination Product: DTPa-HBV-IPV+Hib; Drug: Placebo Sponsors: GlaxoSmithKline; European& Developing Countries Clinical Trials Partnership; Kwame Nkrumah University of Science and Technology; Pedvac iNTS consortium Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 19, 2024 Category: Research Source Type: clinical trials

Antibiotics and Vaccine Immune Responses Study
Conditions: Vaccine Response Impaired Interventions: Biological: BCG vaccine; Biological: Yellow Fever vaccine; Drug: Vancomycin Oral Capsule; Drug: Neomycin Oral Product Sponsors: South Australian Health and Medical Research Institute; Royal Adelaide Hospital; Flinders University; University of Sydney; Telethon Kids Institute; Centenary Institute of Cancer Medicine and Cell Biology Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials

Yellow Fever Human Infection Model With YF-17D
Condition:   Yellow Fever Intervention:   Drug: Yellow Fever Vaccine Sponsors:   Leiden University Medical Center;   The International Society of Travel Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 13, 2023 Category: Research Source Type: clinical trials

Immunogenicity of Yellow Fever Vaccine 17D in Adults With Prior 17D Vaccination
Conditions:   Yellow Fever;   Immunization; Infection Intervention:   Biological: 17D Sponsor:   Oregon Health and Science University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 16, 2023 Category: Research Source Type: clinical trials