Stigma experiences, effects and coping among individuals affected by Buruli ulcer and yaws in Ghana
Conclusions and significanceThe types and levels of stigma varied for BU and yaws. Stigma experiences also differed for adults and children in this setting and these differences should be accounted for in integrated interventions for these skin NTDs. School health programs need to prioritize educating school teachers about skin NTDs and the negative impact of stigma on the wellbeing of children. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - April 29, 2024 Category: Tropical Medicine Authors: Ruth Dede Tuwor Source Type: research
Yaws could soon be eradicated — 70 years behind schedule
Nature, Published online: 11 January 2024; doi:10.1038/d41586-024-00013-yResearchers are cautiously optimistic that the neglected tropical disease could be gone by 2030, but new barriers — including antibiotic resistance and primate reservoirs — might stand in the way. (Source: Nature AOP)
Source: Nature AOP - January 11, 2024 Category: Research Authors: Sam Jones Source Type: research
Low genetic diversity of < i > Treponema pallidum < /i > ssp. < i > pertenue < /i > (TPE) isolated from patients ’ ulcers in Namatanai District of Papua New Guinea: Local human population is infected by three TPE genotypes
by Monica Medappa, Petra Posp íšilová, Maria Paula M. Madruga, Lucy N. John, Camila G. Beiras, Linda Grillová, Jan Oppelt, Arka Banerjee, Marti Vall-Mayans, Oriol Mitjà, David Šmajs
Yaws is an endemic disease caused byTreponema pallidum subsp.pertenue (TPE) that primarily affects children in rural regions of the tropics. The endemic character of yaws infections and the expected exclusive reservoir of TPE in humans opened a new opportunity to start a yaws eradication campaign. We have developed a multi-locus sequence typing (MLST) scheme for TPE isolates combining the previously published (TP0548, TP0488) and new (TP...
Source: PLoS Neglected Tropical Diseases - January 2, 2024 Category: Tropical Medicine Authors: Monica Medappa Source Type: research
The current status of neglected tropical diseases in Japan: A scoping review
by Yuriko Harada, Hanako Iwashita, Taeko Moriyasu, Sachiyo Nagi, Nobuo Saito, Mariko Sugawara-Mikami, Kota Yoshioka, Rie Yotsu, on behalf of Japan NTD Study Group
Little attention has been paid to neglected tropical diseases (NTDs) in high-income countries and no literature provides an overview of NTDs in Japan. This scoping review aims to synthesize the latest evidence and information to understand epidemiology of and public health response to NTDs in Japan. Using three academic databases, we retrieved articles that mentioned NTDs in Japan, written in English or Japanese, and published between 2010 and 2020. Websites of ...
Source: PLoS Neglected Tropical Diseases - January 2, 2024 Category: Tropical Medicine Authors: Yuriko Harada Source Type: research
Prevalence and risk factors associated with < i > Haemophilus ducreyi < /i > cutaneous ulcers in Cameroon
The objective of this study was to determine the prevalence ofHD as cause of cutaneous ulcers, investigate its presence in asymptomatic individuals and identify associated risk factors. A cross-sectional study was conducted in yaws endemic districts of Cameroon. Participants included people presenting yaws-like ulcers and asymptomatic individuals. Swab samples were collected from each participant and tested forHD andTreponema pallidum (TP) using an established qPCR method. Additionally, demographic, habitat, proximity, and hygiene characteristics were collected using a structured questionnaire. A total of 443 individuals p...
Source: PLoS Neglected Tropical Diseases - December 27, 2023 Category: Tropical Medicine Authors: Philippe Ndzomo Source Type: research
Is there still yaws in Nigeria? Active case search in endemic areas of southern Nigeria
ConclusionsNo case of yaws was confirmed in this large population of children in south-east Nigeria. Continuous community awareness and yaws case finding activities have been recommended across Nigeria. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - November 20, 2023 Category: Tropical Medicine Authors: Ngozi Ekeke Source Type: research
Endemic infectious cutaneous ulcers syndrome in the Oti Region of Ghana: Study of cutaneous leishmaniasis, yaws and < i > Haemophilus ducreyi < /i > cutaneous ulcers
Conclusions/SignificanceThis study detected single and mixed occurrence of the causative organisms of CL, yaws, andH.ducreyi cutaneous ulcers in CL endemic communities of the Oti Region in Ghana. These findings emphasize the importance of integrating multiple skin diseases on a common research platform and calls for the development of a comprehensive guideline for diagnosing and treating tropical ulcers in the study areas. (Source: PLoS One)
Source: PLoS One - September 27, 2023 Category: Biomedical Science Authors: Richard Adjei Akuffo Source Type: research
How to find a forgotten disease like yaws: Lessons from the Philippine experience
by Belen Lardizabal Dofitas (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - September 14, 2023 Category: Tropical Medicine Authors: Belen Lardizabal Dofitas Source Type: research
The genomes of the yaws bacterium, < i > Treponema pallidum < /i > subsp. < i > pertenue < /i > , of nonhuman primate and human origin are not genomically distinct
Conclusion/SignificanceOur data show that NHPs are infected with strains that are not only similar to the strains infecting humans but are genomically indistinguishable from them. Although interspecies transmission in NHPs is a rare event and evidence for current spillover events is missing, the existence of the yaws bacterium in NHPs is demonstrated. While the low risk of spillover supports the current yaws treatment campaign, it is of importance to continue yaws surveillance in areas where NHPs are naturally infected withTPE even if yaws is successfully eliminated in humans. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - September 13, 2023 Category: Tropical Medicine Authors: Kl ára Janečková Source Type: research
An mHealth App (eSkinHealth) for Detecting and Managing Skin Diseases in Resource-Limited Settings: Mixed Methods Pilot Study
CONCLUSIONS: The study provided evidence for the usability and effectiveness of the eSkinHealth app embedded into our surveillance approach to improve the detection and management of skin NTDs and other skin diseases in Côte d'Ivoire and, furthermore, is expected to contribute to knowledge on mobile health approaches in the control of skin diseases in resource-limited settings.TRIAL REGISTRATION: ClinicalTrials.gov NCT05300399; https://clinicaltrials.gov/ct2/show/NCT05300399.PMID:37632977 | PMC:PMC10335127 | DOI:10.2196/46295 (Source: Rural Remote Health)
Source: Rural Remote Health - August 26, 2023 Category: Rural Health Authors: Rie R Yotsu Diabate Almamy Bamba Vagamon Kazuko Ugai Sakiko Itoh Yao Didier Koffi Mamadou Kaloga Ligu é Agui Sylvestre Dizoé Kouam é Kouadio N'guetta Aka Luc Kowaci Gontran Yeboue Koffi Aubin Yao Ronald E Blanton Source Type: research
An mHealth App (eSkinHealth) for Detecting and Managing Skin Diseases in Resource-Limited Settings: Mixed Methods Pilot Study
CONCLUSIONS: The study provided evidence for the usability and effectiveness of the eSkinHealth app embedded into our surveillance approach to improve the detection and management of skin NTDs and other skin diseases in Côte d'Ivoire and, furthermore, is expected to contribute to knowledge on mobile health approaches in the control of skin diseases in resource-limited settings.TRIAL REGISTRATION: ClinicalTrials.gov NCT05300399; https://clinicaltrials.gov/ct2/show/NCT05300399.PMID:37632977 | DOI:10.2196/46295 (Source: Rural Remote Health)
Source: Rural Remote Health - August 26, 2023 Category: Rural Health Authors: Rie R Yotsu Diabate Almamy Bamba Vagamon Kazuko Ugai Sakiko Itoh Yao Didier Koffi Mamadou Kaloga Ligu é Agui Sylvestre Dizoé Kouam é Kouadio N'guetta Aka Luc Kowaci Gontran Yeboue Koffi Aubin Yao Ronald E Blanton Source Type: research
Scientific literature on neglected tropical diseases: a bibliometric analysis
Pathog Glob Health. 2023 Aug 22:1-8. doi: 10.1080/20477724.2023.2250619. Online ahead of print.ABSTRACTNeglected tropical diseases (NTDs) are a group of diseases mainly affecting people in low- and middle-income Countries. The aim of this study was to perform a bibliometric analysis of the scientific literature on NTDs. Using the MeSH database, we quantified the number of publications on MEDLINE targeting each NTD, which were published from 1 January 1999 to 31 January 2019. In order to weight the number of publications targeting a given NTD according to the total number of publications/year, we calculated a Yearly Publica...
Source: Pathogens and Global Health - August 22, 2023 Category: International Medicine & Public Health Authors: Gianpiero Tebano Elisa Vanino Paolo Muratori Francesco Cristini Source Type: research
