A call to research: the relationship between SARS-2-CoV, ACE 2 and antihypertensives.
Authors: Cassone A, Gucciardo D, Cauda R PMID: 32450774 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - May 28, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Forecasting tuberculosis using diabetes-related google trends data.
Authors: Frauenfeld L, Nann D, Sulyok Z, Feng YS, Sulyok M Abstract Online activity-based data can be used to aid infectious disease forecasting. Our aim was to exploit the converging nature of the tuberculosis (TB) and diabetes epidemics to forecast TB case numbers. Thus, we extended TB prediction models based on traditional data with diabetes-related Google searches. We obtained data on the weekly case numbers of TB in Germany from June 8th, 2014, to May 5th, 2019. Internet search data were obtained from a Google Trends (GTD) search for 'diabetes' to the corresponding interval. A seasonal autoregressive moving av...
Source: Pathogens and Global Health - May 28, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

COVID-19 and civil war in Libya: the current situation.
Authors: Elhadi M, Msherghi A PMID: 32432976 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - May 22, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Validation of dried blood spots in monitoring toxoplasmosis.
This study included 101 study subjects were occupationally at-risk to Toxoplasma gondii infection and 33 as controls. Serum was collected from both groups for the detection of anti-Toxoplasma IgG antibodies by ELISA as a reference gold standard test. For the occupational at-risk group, capillary finger stick derived blood was blotted onto five sets of Whatman protein saver cards. Discs were stored as four sets; three sets at 4°C and eluted 1, 2 and 3 months of storage and one set at -20°C for 3 months then eluted. Additionally, one set was eluted immediately. Anti-Toxoplasma IgG antibodies were evaluated by EL...
Source: Pathogens and Global Health - May 19, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Recommendation of fecal specimen for routine molecular detection of SARS-CoV-2 and for COVID-19 discharge criteria.
Authors: Ahamed Mim M, Naznin Rakhi N, Saha O, Rahaman MM PMID: 32407189 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - May 16, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Expression levels of candidate circulating microRNAs in pediatric tuberculosis.
Authors: M K, S S, S M Abstract Tuberculosis (TB) is a preventable and curable disease, but increased mortality and morbidity associated with TB is one of the leading causes of deaths worldwide. MicroRNAs (miRNAs) are small, non-coding RNAs known to regulate the host immune response against TB. We investigated the expression profile of candidate circulating miRNAs, which could be used as a blood biomarker for the effective diagnosis of pediatric tuberculosis. A cross-sectional comparative study was conducted, including 30 children with active-TB and 30 healthy controls (HC) in a tertiary care hospital in Puducherry...
Source: Pathogens and Global Health - May 15, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Centralized air-conditioning and transmission of novel coronavirus.
Authors: Siddiqui R, Ahmed Khan N PMID: 32401188 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - May 15, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Hospital epidemiology and antimicrobial susceptibility of isolated methicillin-resistant Staphylococcus aureus: a one-year retrospective study at a tertiary care center in Thailand.
This study aimed to determine the prevalence of methicillin-resistant S. aureus (MRSA) and vancomycin-resistant S. aureus (VRSA) isolates among Thai patients with S. aureus infection and to identify risk factors and appropriate antibiotics for these resistant strains. METHODS: Data of culture-proven S. aureus isolates from clinical specimens during 2017 in King Chulalongkorn Memorial Hospital, Thailand, were retrospectively collected and classified as methicillin-sensitive S. aureus or MRSA by cefoxitin screening and oxacillin minimum inhibitory concentration by the Vitek 2 system. Each isolate was also tested for susc...
Source: Pathogens and Global Health - May 9, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Potential of the natural products against leishmaniasis in Old World - a review of in-vitro studies.
Authors: Cortes S, Bruno de Sousa C, Morais T, Lago J, Campino L Abstract Leishmaniasis is a vector-borne disease among the 10 most Neglected Tropical Diseases with diverse clinical manifestations caused by protozoan parasites of the Leishmania genus. Around 80% of leishmaniasis cases are found in the Old World affecting populations mainly in low and middle-income countries. Its control relies mostly on chemotherapy which still presents many drawbacks. Natural products may offer an inexhaustible source of chemical diversity with therapeutic potential. Despite the lack of knowledge on traditional products with activ...
Source: Pathogens and Global Health - April 29, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Ebola crisis in Eastern Democratic Republic of Congo: student-led community engagement.
We report a student-led educational campaign to increase community awareness and engagement in EVD control efforts, with evaluation of student and community satisfaction. The outreach was conducted in November 2018, involving 600 students and reaching 5-10,000 community members. Key messages included: 'Ebola exists in Butembo' and 'Bring infected family members to the Ebola Treatment Unit.' Medical students (n = 355) and community participants (n = 319) evaluated the campaign. Satisfaction was high: 320 (90%) students agreed that medical students could contribute to the EVD response effort, and 233 (73%...
Source: Pathogens and Global Health - April 22, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Chikungunya fever in Africa: a systematic review.
Authors: Russo G, Subissi L, Rezza G Abstract Since the identification of chikungunya virus (CHIKV), sporadic cases and outbreaks were reported in several African countries, on the Indian subcontinent, and in south-east Asia. In the last 20 years, there is a growing number of reports of CHIKV infections from African countries, but the overall picture of its circulation at the continent level remains ill-characterized because of under-diagnosis and under-reporting. Moreover, the public health impact of the infection in Africa is generally poorly understood, especially during outbreak situations. Our work has th...
Source: Pathogens and Global Health - April 22, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Curcuma longa ethanol extract and Curcumin inhibit the growth of Acanthamoeba triangularis trophozoites and cysts isolated from water reservoirs at Walailak University, Thailand.
Authors: Mitsuwan W, Bunsuwansakul C, Leonard TE, Laohaprapanon S, Hounkong K, Bunluepuech K, Chalermpol K, Mahboob T, Sumudi Raju C, Dhobi M, Pereira ML, Mohammad N, Wiart C, Siyadatpanah A, Norouzi R, Nissapatorn V Abstract Curcuma longa (C. longa) rhizome extract has been traditionally used to treat many infections. Curcumin, a pure compound isolated from the plant, has been documented to possess a wide spectrum of pharmacological effects. The present study aimed to investigate the effects of Thai medicinal plant extracts including C. longa extract and Curcumin on Acanthamoeba triangularis, a causative agent of ...
Source: Pathogens and Global Health - April 22, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Is glucose-6-phosphate dehydrogenase enzyme deficiency a factor in Coronavirus-19 (COVID-19) infections and deaths?
Authors: Aydemir D, Ulusu NN PMID: 32286926 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - April 15, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Intensity of pyrethroid resistance in Anopheles culicifacies s.l. (Diptera: Culicidae) in Odisha State, India.
Authors: Sahu SS, Thankachy S, Dash S, Kasinathan G, Kumar A Abstract Anopheles culicifacies s.l. is the principal malaria vector in India and has recently developed resistance to synthetic pyrethroids. For identifying the possible operational impact, quantitative measure of the intensity of this resistance is required. The purpose of this study was to measure the intensity of pyrethroid resistance in An. culicifacies s.l. The intensity bioassays with wild caught An. culicifacies s.l were carried out in 10 districts of east central India using 5x and 10x diagnostic concentrations of deltamethrin following WHO insec...
Source: Pathogens and Global Health - April 12, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

A holistic approach is needed to control the perpetual burden of soil-transmitted helminth infections among indigenous schoolchildren in Malaysia.
Authors: Nasr NA, Al-Mekhlafi HM, Lim YAL, Elyana FN, Sady H, Atroosh WM, Dawaki S, Al-Delaimy AK, Al-Areeqi MA, Wehaish AA, Anuar TS, Mahmud R Abstract A cross-sectional survey was conducted among 1,142 Orang Ali schoolchildren in six states of Peninsular Malaysia to investigate the current prevalence and risk factors of STH infections. Faecal samples were examined using direct smear, formalin-ether sedimentation, Kato-Katz, and Harada-Mori methods. A pre-tested questionnaire was used to collect information on the demographic, socioeconomic, personal hygiene, and health status of the participants. Overall, 70.1% (...
Source: Pathogens and Global Health - April 8, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Cryptosporidium infection among people living with HIV/AIDS in Ethiopia: a systematic review and meta-analysis.
Authors: Mohebali M, Yimam Y, Woreta A Abstract Studies on the prevalence of Cryptosporidium infection in People Living with HIV/AIDS (PLWHA) are inconsistent and heterogeneous. Therefore, this systematic review with meta-analysis was performed to assess the burden of the infection relative to the proportion of CD4 + T cell count among PLWHA in Ethiopia. Articles published before 15 May 2019, have been retrieved for this systematic review using five databases; PubMed, Scopus, Web of Science, Google Scholar and ProQuest, supplemented by the search for gray literature. The overall pooled prevalence and pool...
Source: Pathogens and Global Health - April 5, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Spa gene-based molecular typing of nasal methicillin-susceptible staphylococcus aureus from patients and health-care workers in a dialysis center in southeast Iran.
This study was conducted to determine the frequency of S. aureus nasal carriage in hemodialysis patients (HD) and health-care workers (HCW) at the main dialysis center of Bam city, located in southeast of Iran. In this cross-sectional study, a total of 52 nasal swabs were obtained from health-care workers and hemodialysis patients to detect methicillin-sensitive S. aureus (MSSA) isolates. The resistance to different antibacterial agents was determined by disk diffusion method. Also, Panton-Valentine Leukocidin (PVL) - encoding gene as well as Staphylococcal protein A (spa) type were determined. The nasal carriage rate of S...
Source: Pathogens and Global Health - March 29, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Knowledge of human monkeypox viral infection among general practitioners: a cross-sectional study in Indonesia.
In conclusion, knowledge of monkeypox among GPs in Indonesia is relatively low in all groups. Increasing knowledge of monkeypox will be key to improving the capacity of GPs to respond to human monkeypox cases and to report into a disease surveillance system. PMID: 32202967 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - March 25, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Toxoplasma gondii infection and risk of attention-deficit hyperactivity disorder: a systematic review and meta-analysis.
This study was registered at the International Prospective Register of Systematic Reviews (PROSPERO; code: CRD42020149353). Odds ratios (ORs) and 95% confidence intervals (CI) were estimated using a random effects model. Seven studies involving five cross-sectional and two case-control studies were included in this meta-analysis.Results indicated that there was a statistically non-significant association between exposure to T. gondii infection and increased risk of ADHD based on the detection of immunoglobulin G (IgG) antibody (2.02 [95% CI: 0.97-4.20]; I2=58.7%). However, obtained results of Egger's tests for anti-T. gond...
Source: Pathogens and Global Health - March 20, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Prevalence Pattern of Chikungunya Virus Infection in Nigeria: A Four Decade Systematic Review and Meta-analysis.
This study aimed to estimate the pooled prevalence pattern of CHIK virus infection in Nigeria. A systematic review of eligible articles was conducted from "PubMed", "Scopus", "Google Scholar" and "Web of Science", between January 1980 to February 2020. Peer-reviewed articles describing CHIKV infection in cross-sectional studies were systematically reviewed. Random-effect model was used to pool the prevalence of CHIKV infection and associated sociodemographic data reported from eligible studies. In total, there were 10 published articles on CHIKV infection. Of these, 7 were cross-sect...
Source: Pathogens and Global Health - March 20, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Identification of suspected paragonimiasis-endemic foci using a questionnaire and detection of Paragonimus ova using the Ziehl-Neelsen technique in Zamboanga Region, the Philippines.
This study aimed to (1) develop a questionnaire to identify suspected paragonimiasis-endemic foci, (2) describe the epidemiology of paragonimiasis, and (3) evaluate Ziehl-Nielsen Staining technique (ZNS) in detecting Paragonimus ova. The questionnaire, which municipal health officers filled out, was based on proposed site inclusion criteria utilized in the integrated tuberculosis (TB)-paragonimiasis surveillance and control project. Newly deployed medical technologists in Zamboanga Region underwent training, which included laboratory diagnosis of paragonimiasis using preserved and fresh specimens and an integrated tub...
Source: Pathogens and Global Health - March 20, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Epidemiological dynamics and associated risk factors of S. haematobium in humans and its snail vectors in Nigeria: a meta-analysis (1983-2018).
Authors: Odeniran PO, Omolabi KF, Ademola IO Abstract Schistosoma haematobium, a major pathogen of urogenital schistosomiasis, has been reported to be affecting an estimated 30 million people in Nigeria. Current national estimates of S. haematobium and its cercariae, in humans and snail vectors respectively, are lacking in Nigeria, hence systematic meta-analyses were conducted to understand the disease dynamics in the endemic country over a period of 35 years based on publications from five databases (AJOL, Ovid MEDLINE, Google Scholar, PubMed and Web of Science). The preferred reporting items for systematic r...
Source: Pathogens and Global Health - March 19, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Public health concerns over gene-drive mosquitoes: will future use of gene-drive snails for schistosomiasis control gain increased level of community acceptance?
Authors: Famakinde DO Abstract With the advent of CRISPR (clustered regularly interspaced short palindromic repeat)-based gene drive, present genetic research in schistosomiasis vector control envisages the breeding and release of transgenic schistosome-resistant (TSR) snail vectors to curb the spread of the disease. Although this approach is still in its infancy, studies focussing on production of genetically modified (GM) mosquitoes (including gene-drive mosquitoes) are well advanced and set the pace for other transgenic vector research. Unfortunately, as with other GM mosquitoes, open field release of gene-drive...
Source: Pathogens and Global Health - February 28, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Fish-borne trematode infections in wild fishes in Bangladesh.
Authors: Labony SS, Alim MA, Hasan MM, Hossain MS, Islam A, Alam MZ, Tsuji N, Anisuzzaman Abstract Fish-borne liver and intestinal flukes are helminth pathogens that have a negative impact on public health worldwide. We herein investigated the status of infection by the metacercariae (MC) of fish-borne trematodes (FBTs) in randomly selected freshwater wild fishes. Five species of fishes were collected and digested artificially using digestion fluid to recover MC. All fish species, namely, ticto barb (Puntius ticto) (14/16, 87.5%), banded gourami (Colisa fasciata) (8/12, 66.7%), freshwater garfish (Xenentodon cancil...
Source: Pathogens and Global Health - February 15, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

The global spread of 2019-nCoV: a molecular evolutionary analysis.
Authors: Benvenuto D, Giovanetti M, Salemi M, Prosperi M, De Flora C, Junior Alcantara LC, Angeletti S, Ciccozzi M Abstract The global spread of the 2019-nCoV is continuing and is fast moving, as indicated by the WHO raising the risk assessment to high. In this article, we provide a preliminary phylodynamic and phylogeographic analysis of this new virus. A Maximum Clade Credibility tree has been built using the 29 available whole genome sequences of 2019-nCoV and two whole genome sequences that are highly similar sequences from Bat SARS-like Coronavirus available in GeneBank. We are able to clarify the mechanism of...
Source: Pathogens and Global Health - February 14, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Nontuberculous mycobacterial infections in a Brazilian pediatric population: a seven-year survey.
Authors: Mauch RM, Mansinho AAS, Rocha PMO, Zaccariotto TR, Levy CE, Nolasco da Silva MT Abstract The aim of this study was to describe the frequency of nontuberculous mycobacteria (NTM) isolation and their related outcomes among pediatric patients of a Brazilian university hospital from 2012 to 2019. NTM were identified in different clinical samples by microbiological culture and molecular-based methods. NTM were isolated from 14 patients, out of whom four (27%) were infected and were treated accordingly. Two were infected with Mycobacterium avium complex (MAC), two with M. abscessus complex (MABSC) and one with M...
Source: Pathogens and Global Health - February 12, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Elevated levels of IL-8 in fatal leptospirosis.
This study aimed to evaluate the significance of IL-8 with the clinical outcomes of leptospirosis patients. Plasma IL-8 was measured in fifty-two samples from hospitalized patients and nineteen healthy controls. The comparisons were made between mild, severe-survived and fatal groups identified by clinical or laboratory findings. IL-8 was significantly higher in fatal (p = 0.01) compared to mild cases. IL-8 was also significantly higher in fatal (p = 0.02) when compared to survived cases of leptospirosis. IL-8 levels in the plasma of fatal leptospirosis cases were significantly elevated compared to survived cases and may s...
Source: Pathogens and Global Health - February 8, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Prevalence of fluoroquinolone-resistant Salmonella serotypes in Iran: a meta-analysis.
Authors: Khademi F, Vaez H, Ghanbari F, Arzanlou M, Mohammadshahi J, Sahebkar A Abstract The present study was conducted to investigate the antimicrobial susceptibility profiles of Salmonella serotypes, especially fluoroquinolone-resistant strains, recovered from clinical samples in Iran. A full electronic search using related keywords was conducted in Persian and English languages in ISI Web of Knowledge, PubMed, Scopus, Google Scholar and the Scientific Information Database (SID) search engines to find papers published between 1983 and 1 July 2019. According to the inclusion and exclusion criteria, 46 eligible ar...
Source: Pathogens and Global Health - February 7, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Malaria education interventions addressing bed net care and repair practices: a systematic review.
Authors: Santos EM, McClelland DJ, Shelly CE, Hansen L, Jacobs ET, Klimentidis YC, Ernst KC Abstract Education intervention effectiveness to improve bed net care and repair knowledge or practices is unclear. To assess intervention effectiveness, we systematically reviewed eight peer-reviewed literature databases and 16 malaria organizations (PROSPERO protocol CRD42019123932) using pre-specified combinations of 'education intervention', 'mosquito net', and 'malaria' search terms. Data were abstracted for 29 of 43 studies meeting inclusion criteria, of which 16 studies included education as amain focus. Of these 16, ...
Source: Pathogens and Global Health - February 2, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Molecular detection and genotypic characterisation of Streptococcus pneumoniae isolated from children in Malaysia.
This study determined the serotypes of S. pneumoniae strains (n = 95) isolated from nasopharyngeal specimens from children admitted to UMMC from 2013 to 2015. In accordance with previous studies, PCR result showed 40% of NT isolates were successfully typed as 3 less common serotypes, namely 9N/L, 17A, and 23B. The repetitive-element PCR (REP-PCR) result revealed genetic variations among the strains whereby five major clusters were observed at the similarity of 80% by clustering analysis based on fingerprint data. Penicillin-binding proteins (pbps) of selected isolates were studied by PCR and sequencing. Three strains with ...
Source: Pathogens and Global Health - February 2, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

The expanding Anopheles gambiae species complex.
Authors: Loughlin SO PMID: 31997728 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - February 1, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Identification of bloodmeal sources of triatomines captured in the Paraguayan Chaco region of South America by means of molecular biology analysis.
Authors: Fraenkel S, Salvioni OD, de Arias AR, Arze VP, Rolón M, Ramirez N, Vega Gómez C Abstract The Paraguayan Chaco is an isolated environment with its own unique ecosystem. In this region, Chagas disease remains a health problem. Chagas disease is caused by the parasite Trypanosoma cruzi, and it is primarily transmitted by triatomines. In order to identify the blood meal sources of triatomines, specimens of the vector were collected in residential and residential adjacent areas and the PCR-RFLP method was implemented. Cytochrome b was amplified from the samples and later subjected to digestion wit...
Source: Pathogens and Global Health - January 26, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Acute histoplasmosis in travelers: a retrospective study in an Italian referral center for tropical diseases.
Conclusions: Clinical, laboratory and radiological features of histoplasmosis can mimic other conditions, resulting in unnecessary invasive diagnostic procedures. However, a history of travel to endemic areas and of exposure to risk factors (such as visits to caves and presence of bats) should trigger the clinical suspicion of histoplasmosis. Treatment may be indicated in severe or prolonged disease. PMID: 31959091 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - January 23, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Ex vivo efficacy of selective chalcone derivatives on reference strains and field isolates of Plasmodium falciparum.
Authors: Dable MT, Tano KD, Ouattara M, Silue KD, Menan EIH, Yavo W Abstract The extension of Plasmodium falciparum resistance to existing antimalarial drugs is worrying. Faced with this problem, the search for new and effective molecules is necessary. In this context, six chalcone derivatives (B1, B11, B14, B17, SCA02 and SCA03) were tested on field isolates and then reference strains to evaluate their antiplasmodial activity by using the Rieckmann semi-microtest, recommended by WHO, for in vitro and ex vivo activity tests. Compounds B14 and B17 exhibited promising antiplasmodial activities (IC50s: 14.41-16.40 &mu...
Source: Pathogens and Global Health - January 9, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Can Plasmodium's tricks for enhancing its transmission be turned against the parasite? New hopes for vector control.
Authors: Emami SN, Hajkazemian M, Mozūraitis R Abstract Approximately 120 years ago the link between mosquito and the malaria transmission was discovered. However, even today it remains an open question whether the parasite is able to direct the blood-seeking and feeding behavior of its mosquito vector to maximize the probability of transmission. If the parasite has this ability, could it occur only through the alteration of the vertebrate host's volatile organic compounds (VOCs) and/or the parasite alteration of the behavior of the infected vector in a manner that favors its transmission? Although some recent emp...
Source: Pathogens and Global Health - January 9, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Surveillance for Zika in Mexico: naturally infected mosquitoes in urban and semi-urban areas.
Authors: Correa-Morales F, González-Acosta C, Mejía-Zúñiga D, Huerta H, Pérez-Rentería C, Vazquez-Pichardo M, Ortega-Morales AI, Hernández-Triana LM, Salazar-Bueyes VM, Moreno-García M Abstract Zika cases have been reported in 29 out of the 32 states of Mexico. Information regarding which mosquito species might be driving Zika virus transmission/maintenance in nature must be regularly updated. From January 2017 to November 2018, mosquitoes were collected indoors and outdoors using the CDC backpack aspirator in urban and semi-urban areas with evidence of mosqui...
Source: Pathogens and Global Health - January 8, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Development of point-of-care tests for Taenia solium: one of the ways to obtain a better diagnosis and therapeutic management of patients, and to reach eradication.
Authors: Fleury A PMID: 31902345 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - January 8, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Multiple insecticide resistance in Anopheles culicifacies s.l. (Diptera: Culicidae) in east-central India.
Authors: Sahu SS, Thankachy S, Dash S, Swaminathan S, Kasinathan G, Purushothaman J Abstract Development of resistance among the vectors to different insecticides poses a potential threat to vector control programme. Regular monitoring of susceptibility status of vector species to commonly used insecticides is recommended for planning appropriate vector control measures. In this communication, we have determined the phenotypic resistance of Anopheles culicifacies s.l., the major malaria vector against commonly used various insecticides in ten highly malaria endemic districts of Odisha State in east-centra...
Source: Pathogens and Global Health - January 8, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Circulation of M. tuberculosis Beijing genotype in Latin America and the Caribbean.
Authors: Cerezo-Cortés MI, Rodríguez-Castillo JG, Hernández-Pando R, Murcia MI Abstract Lineage 2 (East Asian), which includes the Beijing genotype, is one of the most prevalent lineages of Mycobacterium tuberculosis (Mtb) throughout the world. The Beijing family is associated to hypervirulence and drug-resistant tuberculosis. The study of this genotype's circulation in Latin America is crucial for achieving total control of TB, the goal established by the World Health Organization, for the American sub-continent, before 2035. In this sense, the present work presents an overview of the status o...
Source: Pathogens and Global Health - January 8, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Defining Zika virus infection in pregnant women.
Authors: Ticconi C, Rezza G PMID: 31905106 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - January 8, 2020 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Insect-bacterial mosaic produces peptidoglycan in mealybug.
Authors: Favia G PMID: 31878846 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - December 29, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Genotypic validation of extended-spectrum β-lactamase and virulence factors in multidrug resistance Klebsiella pneumoniae in an Indian hospital.
Genotypic validation of extended-spectrum β-lactamase and virulence factors in multidrug resistance Klebsiella pneumoniae in an Indian hospital. Pathog Glob Health. 2019 Dec 22;:1-7 Authors: Sahoo RK, Das A, Gaur M, Pattanayak A, Sahoo S, Debata NK, Rahman PKSM, Subudhi E Abstract The emergence of extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae has been increasing rapidly across the world. The presence of virulence factors in ESBL producers further adds to the pathogenicity and severity of infection, which often complicate empirical therapy and sometimes result in treatme...
Source: Pathogens and Global Health - December 24, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Mandatory vaccination for infants and children: the Italian experience.
Authors: Rezza G Abstract Maintaining high vaccination coverage is important in order to protect the individual and the community. Mandatory vaccination is an option in case of declining coverage. Widely used in the USA, it is considered a rather controversial issue in Europe. In Italy, after a decrease of vaccination coverage for the hexavalent and the MPR vaccine under the optimal threshold, a new law, which extended the number of mandatory vaccines from 4 to 10 and reinforced coercive measures, was introduced in July 2017. After 2 years, vaccination coverage increased for all mandatory vaccines and for the other...
Source: Pathogens and Global Health - December 24, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Molecular characterization and phylogenetic analysis of human pathogenic Leptospira species circulating in a tertiary care hospital of Western Uttar Pradesh in India.
This study was carried out to explore the genetic characterization and its phylogenetic analysis of circulating Leptospira species, among the Aligarh region of western Uttar Pradesh in India, utilizing secY gene-based nucleotide sequence. A total of 190 human samples were included in the study. Positive samples were identified by ELISA, MAT and PCR. MAT was carried out utilizing local circulating Leptospira serovars. Four positive samples including two MAT positive samples were subjected to DNA sequencing for further confirmation and phylogenetic tree was constructed. Out of the total of 190 samples, 24 patients were found...
Source: Pathogens and Global Health - December 12, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Helminthiasis among North Koreans: a chronic public health challenge.
Authors: Park KB, Shafik NM PMID: 31818237 [PubMed - in process] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - December 12, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Plasmid profile and role in virulence of salmonella enterica serovars isolated from food animals and humans in Lagos Nigeria.
Authors: Abraham A, Ifeanyi SS, Muinah F, Ibidunni Oreoluwa BS, Coulibaly KJ, Adeyemi AI Abstract Infections caused by non-typhoidal Salmonella (NTS) are common around the world, with high morbidity and mortality rates recorded annually. Salmonella serovars harbor plasmids of various sizes which may play roles in antibiotic resistance and virulence. The aim of this study was to profile and determine the role of plasmids in ciprofloxacin resistance and virulence of Salmonella serovars. Using alkaline lysis method 25 NTS serovars from food animals and humans were assayed for plasmids. Isolates ability to resist healt...
Source: Pathogens and Global Health - December 12, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Achieving accurate laboratory diagnosis of typhoid fever: a review and meta-analysis of TUBEX ® TF clinical performance.
Achieving accurate laboratory diagnosis of typhoid fever: a review and meta-analysis of TUBEX® TF clinical performance. Pathog Glob Health. 2019 Nov 28;:1-12 Authors: Bundalian R, Valenzuela M, Tiongco RE Abstract This review discusses currently available serological diagnostic methods for typhoid fever with a focus on the clinical utility of TUBEX® TF as an alternative to the Widal or Typhidot test. A literature search was conducted in PubMed for related publications written in English. A qualitative analysis was done to determine various serological tests used for typhoid fever diagnosis with...
Source: Pathogens and Global Health - November 30, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Molecular characterization of multidrug-resistant Shiga toxin-producing Escherichia coli harboring antimicrobial resistance genes obtained from a farmhouse.
This study reports for the first time, the presence of MDR STEC and non-STEC belonging to ST25, ST162, ST642, ST1247, ST1518, ST1725, ST2107, ST3270, ST5036, and ST7100 in sheep, and contributes to the surveillance studies associated with One Health concept. PMID: 31757195 [PubMed - as supplied by publisher] (Source: Pathogens and Global Health)
Source: Pathogens and Global Health - November 24, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Seroprevalence and risk factors of hepatitis B virus infection in tribal population of Himalayan district Lahaul and Spiti, India.
Authors: Sharma RK, Shukla MK, Minhas N, Barde PV Abstract Hepatitis B virus (HBV) infection is an important health issue across the world. With 4% to 7% prevalence of HBV, India is designated as an intermediate endemic country. However, HBV prevalence is significantly high in some pockets of the country, especially among tribal populations. HBV prevalence and associated risk factors in residents of far-flung two Himalayan valleys, Lahaul and Spiti of Himachal Pradesh (HP), were estimated. This was a community-based cross-sectional study. Blood samples were collected and tested for the presence of hepatitis B surfa...
Source: Pathogens and Global Health - November 6, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research

Arboviruses in the East African Community partner states: a review of medically important mosquito-borne Arboviruses.
Authors: Nyaruaba R, Mwaliko C, Mwau M, Mousa S, Wei H Abstract Mosquito-borne diseases, including arbovirus-related diseases, make up a large proportion of infectious disease cases worldwide, causing a serious global public health burden with over 700,000 deaths annually. Mosquito-borne arbovirus outbreaks can range from global to regional. In the East African Community (EAC) region, these viruses have caused a series of emerging and reemerging infectious disease outbreaks. Member states in the EAC share a lot in common including regional trade and transport, some of the factors highlighted to be the cause of mosq...
Source: Pathogens and Global Health - October 31, 2019 Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research