Improved rapid diagnostic tests to detect syphilis and yaws: a systematic review and meta-analysis
Conclusions
RDTs that can differentiate between active and previously treated infections could optimise management by providing same-day treatment and reducing unnecessary treatment.
PROSPERO registration number
CRD42021279587. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - November 17, 2022 Category: Sexual Medicine Authors: Zhang, Y., Goh, S. M., Mello, M. B., Baggaley, R. C., Wi, T., Johnson, C. C., Asiedu, K. B., Marks, M., Pham, M. D., Fairley, C. K., Chow, E. P. F., Mitja, O., Toskin, I., Ballard, R. C., Ong, J. J. Tags: Open access Review Source Type: research
A combined effort of 11 laboratories in the WHO African region to improve quality of Buruli ulcer PCR diagnosis: The “BU-LABNET”
by Estelle Marion, Numfor Hycenth, Sundeep Chaitanya Vedithi, Marie Robbe-Saule, Val érie Donkeng, Line-Marlène Ganlonon, Affolabi Dissou, Solange Kakou Ngazoa, Marie-Jose Kabedi, Arsène Mabika Mabika, Richard Phillips, Michael Frimpong, Dorothy Yeboah-Manu, Vera Yatta Walker, Olaoluwa Akinwale, Maman Issaka, Gisela Bretzel, Kinsgley Asiedu, Sara Eyangoh
Buruli ulcer is one of the 20 neglected tropical diseases in the world. This necrotizing hypodermitis is a chronic debilitating disease caused by an environmentalMycobacterium ulcerans. At least 33 countries with tropical, subtropical and temperate climates have report...
Source: PLoS Neglected Tropical Diseases - November 4, 2022 Category: Tropical Medicine Authors: Estelle Marion Source Type: research
Skin wounds in a rural setting of C ôte d’Ivoire: Population-based assessment of the burden and clinical epidemiology
ConclusionsSkin wounds are highly prevalent in rural West Africa, where they represent a widely neglected problem. The HDSS-based survey with combined active and passive case finding adopted in this study provides a better estimate than school- and health institution-based surveys which underestimate the frequency of skin wounds and, particularly, of neglected tropical diseases of the skin, such as Buruli ulcer and yaws. A comparison with country-specific WHO data suggests underreporting of Buruli ulcer cases. Trial registrationRegistration at ClinicalTrials.gov NCT03957447. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - October 13, 2022 Category: Tropical Medicine Authors: Simone Toppino Source Type: research
Diagnostics to support the eradication of yaws —Development of two target product profiles
ConclusionsThe TPPs developed will provide test developers with guidance to ensure that novel diagnostic tests meet identified public health needs. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - September 1, 2022 Category: Tropical Medicine Authors: Noah Fongwen Source Type: research
Quantifying Population Burden and Effectiveness of Decentralized Surveillance Strategies for Skin-Presenting Neglected Tropical Diseases, Liberia
Emerg Infect Dis. 2022 Sep;28(9):1755-1764. doi: 10.3201/eid2809.212126.ABSTRACTWe evaluated programmatic approaches for skin neglected tropical disease (NTD) surveillance and completed a robust estimation of the burden of skin NTDs endemic to West Africa (Buruli ulcer, leprosy, lymphatic filariasis morbidity, and yaws). In Maryland, Liberia, exhaustive case finding by community health workers of 56,285 persons across 92 clusters identified 3,241 suspected cases. A total of 236 skin NTDs (34.0 [95% CI 29.1-38.9]/10,000 persons) were confirmed by midlevel healthcare workers trained using a tailored program. Cases showed a f...
Source: Emerging Infectious Diseases - August 23, 2022 Category: Infectious Diseases Authors: Joseph W S Timothy Emerson Rogers Katherine E Halliday Tarnue Mulbah Michael Marks Zeela Zaizay Romeo Giddings Marie Kempf Estelle Marion Stephen L Walker Karsor K Kollie Rachel L Pullan Source Type: research
Quantifying Population Burden and Effectiveness of Decentralized Surveillance Strategies for Skin-Presenting Neglected Tropical Diseases, Liberia
Emerg Infect Dis. 2022 Sep;28(9):1755-1764. doi: 10.3201/eid2809.212126.ABSTRACTWe evaluated programmatic approaches for skin neglected tropical disease (NTD) surveillance and completed a robust estimation of the burden of skin NTDs endemic to West Africa (Buruli ulcer, leprosy, lymphatic filariasis morbidity, and yaws). In Maryland, Liberia, exhaustive case finding by community health workers of 56,285 persons across 92 clusters identified 3,241 suspected cases. A total of 236 skin NTDs (34.0 [95% CI 29.1-38.9]/10,000 persons) were confirmed by midlevel healthcare workers trained using a tailored program. Cases showed a f...
Source: Emerging Infectious Diseases - August 23, 2022 Category: Infectious Diseases Authors: Joseph W S Timothy Emerson Rogers Katherine E Halliday Tarnue Mulbah Michael Marks Zeela Zaizay Romeo Giddings Marie Kempf Estelle Marion Stephen L Walker Karsor K Kollie Rachel L Pullan Source Type: research
Secondary Effects from Mass Azithromycin Administration: A Systematic Review and Meta-analysis
In conclusion, azithromycin MDA had favorable secondary effects on child mortality and morbidity. However, the effects were short term.PMID:35970284 | DOI:10.4269/ajtmh.22-0134 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - August 15, 2022 Category: Tropical Medicine Authors: Jinhui Li Tao Xiong Yan Yue Imti Choonara Shamim Qazi Jun Tang Jing Shi Hua Wang Yi Qu Dezhi Mu Source Type: research
Secondary Effects from Mass Azithromycin Administration: A Systematic Review and Meta-analysis
In conclusion, azithromycin MDA had favorable secondary effects on child mortality and morbidity. However, the effects were short term.PMID:35970284 | DOI:10.4269/ajtmh.22-0134 (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - August 15, 2022 Category: Infectious Diseases Authors: Jinhui Li Tao Xiong Yan Yue Imti Choonara Shamim Qazi Jun Tang Jing Shi Hua Wang Yi Qu Dezhi Mu Source Type: research
Secondary Effects from Mass Azithromycin Administration: A Systematic Review and Meta-analysis
In conclusion, azithromycin MDA had favorable secondary effects on child mortality and morbidity. However, the effects were short term.PMID:35970284 | DOI:10.4269/ajtmh.22-0134 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - August 15, 2022 Category: Tropical Medicine Authors: Jinhui Li Tao Xiong Yan Yue Imti Choonara Shamim Qazi Jun Tang Jing Shi Hua Wang Yi Qu Dezhi Mu Source Type: research
