ADAMTS13 inhibits H < sub > 2 < /sub > O < sub > 2 < /sub > -induced human venous endothelial cell injury to attenuate deep-vein thrombosis by blocking the p38/ERK signaling pathway
This study was aimed to explore the role of ADAMTS13 in endothelial cell injury during DVT and the possible mechanism. First, human umbilical vein endothelial cells (HUVECs) were exposed to hydrogen peroxide (H2O2). Then, the mRNA and protein expressions of ADAMTS13 were evaluated with the reverse transcription-quantitative polymerase chain reaction and western blot. After treatment with recombinant ADAMTS13 (rADAMTS13; rA13), the viability and apoptosis of H2O2-induced HUVECs were assessed by cell counting kit-8 assay and terminal-deoxynucleoitidyl transferase-mediated nick end labeling staining. In addition, the levels o...
Source: The Chinese Journal of Physiology - December 27, 2023 Category: Physiology Authors: Guangfeng Zheng Qiang Zhang Chuanyong Li Weijian Fan Zhichang Pan Yuting Zhou Yan Chen Jianjie Rong Source Type: research
Evaluation of a diagnostic platelet aggregation test strategy for platelet rich plasma samples with low platelet counts
CONCLUSION: Diagnostic LTA with L-PRP, using a strategy that considers thrombocytopenia severity, is feasible and informative.PMID:38148642 | DOI:10.1111/ijlh.14216 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 27, 2023 Category: Hematology Authors: Rahaf Mahmoud Altahan Natalie Mathews Alex Bourguignon Subia Tasneem Donald M Arnold Wendy Lim Catherine P M Hayward Source Type: research
ADAMTS13 inhibits H < sub > 2 < /sub > O < sub > 2 < /sub > -induced human venous endothelial cell injury to attenuate deep-vein thrombosis by blocking the p38/ERK signaling pathway
This study was aimed to explore the role of ADAMTS13 in endothelial cell injury during DVT and the possible mechanism. First, human umbilical vein endothelial cells (HUVECs) were exposed to hydrogen peroxide (H2O2). Then, the mRNA and protein expressions of ADAMTS13 were evaluated with the reverse transcription-quantitative polymerase chain reaction and western blot. After treatment with recombinant ADAMTS13 (rADAMTS13; rA13), the viability and apoptosis of H2O2-induced HUVECs were assessed by cell counting kit-8 assay and terminal-deoxynucleoitidyl transferase-mediated nick end labeling staining. In addition, the levels o...
Source: The Chinese Journal of Physiology - December 27, 2023 Category: Physiology Authors: Guangfeng Zheng Qiang Zhang Chuanyong Li Weijian Fan Zhichang Pan Yuting Zhou Yan Chen Jianjie Rong Source Type: research
Evaluation of a diagnostic platelet aggregation test strategy for platelet rich plasma samples with low platelet counts
CONCLUSION: Diagnostic LTA with L-PRP, using a strategy that considers thrombocytopenia severity, is feasible and informative.PMID:38148642 | DOI:10.1111/ijlh.14216 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 27, 2023 Category: Hematology Authors: Rahaf Mahmoud Altahan Natalie Mathews Alex Bourguignon Subia Tasneem Donald M Arnold Wendy Lim Catherine P M Hayward Source Type: research
ADAMTS13 inhibits H < sub > 2 < /sub > O < sub > 2 < /sub > -induced human venous endothelial cell injury to attenuate deep-vein thrombosis by blocking the p38/ERK signaling pathway
This study was aimed to explore the role of ADAMTS13 in endothelial cell injury during DVT and the possible mechanism. First, human umbilical vein endothelial cells (HUVECs) were exposed to hydrogen peroxide (H2O2). Then, the mRNA and protein expressions of ADAMTS13 were evaluated with the reverse transcription-quantitative polymerase chain reaction and western blot. After treatment with recombinant ADAMTS13 (rADAMTS13; rA13), the viability and apoptosis of H2O2-induced HUVECs were assessed by cell counting kit-8 assay and terminal-deoxynucleoitidyl transferase-mediated nick end labeling staining. In addition, the levels o...
Source: The Chinese Journal of Physiology - December 27, 2023 Category: Physiology Authors: Guangfeng Zheng Qiang Zhang Chuanyong Li Weijian Fan Zhichang Pan Yuting Zhou Yan Chen Jianjie Rong Source Type: research
Evaluation of a diagnostic platelet aggregation test strategy for platelet rich plasma samples with low platelet counts
CONCLUSION: Diagnostic LTA with L-PRP, using a strategy that considers thrombocytopenia severity, is feasible and informative.PMID:38148642 | DOI:10.1111/ijlh.14216 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 27, 2023 Category: Hematology Authors: Rahaf Mahmoud Altahan Natalie Mathews Alex Bourguignon Subia Tasneem Donald M Arnold Wendy Lim Catherine P M Hayward Source Type: research
ADAMTS13 inhibits H < sub > 2 < /sub > O < sub > 2 < /sub > -induced human venous endothelial cell injury to attenuate deep-vein thrombosis by blocking the p38/ERK signaling pathway
This study was aimed to explore the role of ADAMTS13 in endothelial cell injury during DVT and the possible mechanism. First, human umbilical vein endothelial cells (HUVECs) were exposed to hydrogen peroxide (H2O2). Then, the mRNA and protein expressions of ADAMTS13 were evaluated with the reverse transcription-quantitative polymerase chain reaction and western blot. After treatment with recombinant ADAMTS13 (rADAMTS13; rA13), the viability and apoptosis of H2O2-induced HUVECs were assessed by cell counting kit-8 assay and terminal-deoxynucleoitidyl transferase-mediated nick end labeling staining. In addition, the levels o...
Source: The Chinese Journal of Physiology - December 27, 2023 Category: Physiology Authors: Guangfeng Zheng Qiang Zhang Chuanyong Li Weijian Fan Zhichang Pan Yuting Zhou Yan Chen Jianjie Rong Source Type: research
Evaluation of a diagnostic platelet aggregation test strategy for platelet rich plasma samples with low platelet counts
CONCLUSION: Diagnostic LTA with L-PRP, using a strategy that considers thrombocytopenia severity, is feasible and informative.PMID:38148642 | DOI:10.1111/ijlh.14216 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 27, 2023 Category: Hematology Authors: Rahaf Mahmoud Altahan Natalie Mathews Alex Bourguignon Subia Tasneem Donald M Arnold Wendy Lim Catherine P M Hayward Source Type: research
ADAMTS13 inhibits H < sub > 2 < /sub > O < sub > 2 < /sub > -induced human venous endothelial cell injury to attenuate deep-vein thrombosis by blocking the p38/ERK signaling pathway
This study was aimed to explore the role of ADAMTS13 in endothelial cell injury during DVT and the possible mechanism. First, human umbilical vein endothelial cells (HUVECs) were exposed to hydrogen peroxide (H2O2). Then, the mRNA and protein expressions of ADAMTS13 were evaluated with the reverse transcription-quantitative polymerase chain reaction and western blot. After treatment with recombinant ADAMTS13 (rADAMTS13; rA13), the viability and apoptosis of H2O2-induced HUVECs were assessed by cell counting kit-8 assay and terminal-deoxynucleoitidyl transferase-mediated nick end labeling staining. In addition, the levels o...
Source: The Chinese Journal of Physiology - December 27, 2023 Category: Physiology Authors: Guangfeng Zheng Qiang Zhang Chuanyong Li Weijian Fan Zhichang Pan Yuting Zhou Yan Chen Jianjie Rong Source Type: research
Evaluation of a diagnostic platelet aggregation test strategy for platelet rich plasma samples with low platelet counts
CONCLUSION: Diagnostic LTA with L-PRP, using a strategy that considers thrombocytopenia severity, is feasible and informative.PMID:38148642 | DOI:10.1111/ijlh.14216 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - December 27, 2023 Category: Hematology Authors: Rahaf Mahmoud Altahan Natalie Mathews Alex Bourguignon Subia Tasneem Donald M Arnold Wendy Lim Catherine P M Hayward Source Type: research
ADAMTS13 inhibits H < sub > 2 < /sub > O < sub > 2 < /sub > -induced human venous endothelial cell injury to attenuate deep-vein thrombosis by blocking the p38/ERK signaling pathway
This study was aimed to explore the role of ADAMTS13 in endothelial cell injury during DVT and the possible mechanism. First, human umbilical vein endothelial cells (HUVECs) were exposed to hydrogen peroxide (H2O2). Then, the mRNA and protein expressions of ADAMTS13 were evaluated with the reverse transcription-quantitative polymerase chain reaction and western blot. After treatment with recombinant ADAMTS13 (rADAMTS13; rA13), the viability and apoptosis of H2O2-induced HUVECs were assessed by cell counting kit-8 assay and terminal-deoxynucleoitidyl transferase-mediated nick end labeling staining. In addition, the levels o...
Source: The Chinese Journal of Physiology - December 27, 2023 Category: Physiology Authors: Guangfeng Zheng Qiang Zhang Chuanyong Li Weijian Fan Zhichang Pan Yuting Zhou Yan Chen Jianjie Rong Source Type: research
