Awareness and Knowledge Among Internal Medicine Resident Trainees for Dose Adjustment of Analgesics and Neuropsychotropic Medications in CKD.
CONCLUSIONS: Awareness and knowledge are poor among IMRTs for dose adjustments of analgesics and neuropsychotropic medication classes in patients with CKD. There should be a renewed focus during IMRTs' residency on additional nephrology exposure and formal didactic educational training to help them better manage complex treatment regimens to prevent medication dosing errors. PMID: 29505650 [PubMed - in process] (Source: Southern Medical Journal)
Source: Southern Medical Journal - March 7, 2018 Category: General Medicine Tags: South Med J Source Type: research

Patterns of pain medication use in older individuals with cardiovascular disease.
CONCLUSION: We described the patterns of use of pain medications among older adults with cardiovascular disease. Careful selection of appropriate pain medications based on different clinical parameters is very essential to avoid prescribing inappropriate therapy that can lead to patient harm. PMID: 29490511 [PubMed - as supplied by publisher] (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - March 3, 2018 Category: Research Tags: Curr Med Res Opin Source Type: research

Chikungunya fever: General and oral healthcare implications
Chikungunya virus (CHIKV) was first isolated in humans in 1952, following an epidemic in Tanzania. The origin of the name means “to bend forward or become contorted,” in reference to the posture adopted by patients due to the joint pain that occurs during the infection. Epidemiology data suggest that by the end of 2015, about 1.6 million people had been infected with CHIKV. The acute period of the disease is characterized by high fever, myalgia, joint pain, and severe and disabling polyarthritis, sometimes accompanied by headache, backache, and maculopapular rash, predominantly on the thorax. Around half of the patient...
Source: Oral Diseases - February 26, 2018 Category: ENT & OMF Authors: JC Leao, CDL Marques, ALBP Duarte, OP Almeida, S Porter, LA Gueiros Tags: PROF SCULLY MEMORIAL ISSUE Source Type: research

Effect of oral premedication on the anaesthetic efficacy of inferior alveolar nerve block in patients with irreversible pulpitis – A systematic review and network meta‐analysis of randomized controlled trials
This article is protected by copyright. All rights reserved. (Source: International Endodontic Journal)
Source: International Endodontic Journal - February 26, 2018 Category: Dentistry Authors: S J Pulikkotil, V Nagendrababu, S K Veettil, P Jinatongthai, F C Setzer Tags: Review Source Type: research

Comparison of the analgesic effects of a constant rate infusion of both Tramadol and Acetaminophen versus infusions of each individual drug in horses
The choice of analgesic agents for the horse is limited and many have side effects that can restrict their use for chronic and prolonged pain. Little information has been published on Tramadol and Acetaminophen in the horse. The study evaluated the analgesic effects of co-administration of tramadol and acetaminophen compared to each drug individually in a crossover study. The study was performed in 6 healthy horses each infused the following over one hour: Control (normal saline), Tramadol, Acetaminophen, or Both (acetaminophen and tramadol infused together). (Source: Journal of Equine Veterinary Science)
Source: Journal of Equine Veterinary Science - February 21, 2018 Category: Veterinary Research Authors: Hamid Tavanaeimanesh, Afrooz Azarnoosh, Fereidoon Saberi Afshar, Mohammad Mehdi Dehghan, Zeinab Mohebbi, Vahid Akbarinejad, Kevin Corley Tags: Original Research Source Type: research

Comparison of Analgesic Effects of a Constant Rate Infusion of Both Tramadol and Acetaminophen Versus those of Infusions of Each Individual Drug in Horses
The choice of analgesic agents for the horse is limited, and many have side effects that can restrict their use for chronic and prolonged pain. Little information has been published on tramadol and acetaminophen use in the horse. The study evaluated the analgesic effects of coadministration of tramadol and acetaminophen compared to those of each drug individually in a crossover study. The study was performed on six healthy horses each infused with the following over 1 hour: control (normal saline), tramadol, acetaminophen, or both (acetaminophen and tramadol infused together). (Source: Journal of Equine Veterinary Science)
Source: Journal of Equine Veterinary Science - February 21, 2018 Category: Veterinary Research Authors: Hamid Tavanaeimanesh, Afrooz Azarnoosh, Fereidoon Saberi Ashar, Mohammad Mehdi Dehghan, Zeinab Mohebbi, Vahid Akbarinejad, Kevin Corley Tags: Original Research Source Type: research

Combination pharmacotherapy for the treatment of fibromyalgia in adults.
CONCLUSIONS: There are few, large, high-quality trials comparing combination pharmacotherapy with monotherapy for fibromyalgia, consequently limiting evidence to support or refute the use of combination pharmacotherapy for fibromyalgia. PMID: 29457627 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - February 19, 2018 Category: General Medicine Authors: Thorpe J, Shum B, Moore RA, Wiffen PJ, Gilron I Tags: Cochrane Database Syst Rev Source Type: research

Prehospital Analgesia for Pediatric Trauma Patients in Iraq and Afghanistan.
CONCLUSIONS: Overall, a low proportion of pediatric trauma subjects within this population received analgesia in the prehospital environment. The most common analgesic medication administered was morphine. Those receiving analgesic agents had more severe injuries and higher rates of concomitant interventions. These results highlight the potential need for Tactical Combat Casualty Care guidelines specifically providing recommendations for analgesia administration among pediatric patients. PMID: 29412051 [PubMed - as supplied by publisher] (Source: Prehospital Emergency Care)
Source: Prehospital Emergency Care - February 8, 2018 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Pain after tonsillectomy: effectiveness of current guidelines?
ConclusionHome pain management after tonsillectomy should be improved. In clinical practice, A  + I seems at least as effective as the combination A + T, without increasing readmission and/or additional surgery for bleeding. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 1, 2018 Category: ENT & OMF Source Type: research

[Subcostal transversus abdominis plane block can improve analgesia after laparoscopic cholecystectomy].
CONCLUSION: Our results show that subcostal transversus abdominis plane block can provide superior postoperative analgesia and reduction in opioid requirements after laparoscopic cholecystectomy. PMID: 29277312 [PubMed - as supplied by publisher] (Source: Revista Brasileira de Anestesiologia)
Source: Revista Brasileira de Anestesiologia - December 28, 2017 Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research

Evaluation of opioid prescribing after rescheduling of hydrocodone-containing products.
CONCLUSION: The rescheduling of HCPs resulted in a reduction in HCP prescriptions but was accompanied by increases in the use of codeine-containing products and tramadol in all settings. PMID: 29222361 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - December 11, 2017 Category: Drugs & Pharmacology Authors: Bernhardt MB, Taylor RS, Hagan JL, Patel N, Chumpitazi CE, Fox KA, Glover C Tags: Am J Health Syst Pharm Source Type: research

Pain Management Strategies in Shoulder Arthroplasty.
Abstract Pain control in total shoulder arthroplasty demands a multidisciplinary approach with collaboration between patients, surgeon, and anesthetist. A multimodal approach with preemptive medication, regional blockade, local anesthetics, and a combination of acetaminophen, nonsteroidal antiinflammatory drugs, tramadol, and gabapentinoids postoperatively leads to pain control and patient satisfaction. Assessment of patients' expectations constitutes a vital aspect of the preoperative patient evaluation. Educating and psychologically preparing patients reduces postoperative pain. Patients with anxiety and...
Source: The Orthopedic Clinics of North America - November 18, 2017 Category: Orthopaedics Authors: Codding JL, Getz CL Tags: Orthop Clin North Am Source Type: research

Subcostal transversus abdominis plane block can improve analgesia after laparoscopic cholecystectomy
Conclusion Our results show that subcostal transversus abdominis plane block can provide superior postoperative analgesia and reduction in opioid requirements after laparoscopic cholecystectomy. (Source: Brazilian Journal of Anesthesiology)
Source: Brazilian Journal of Anesthesiology - November 15, 2017 Category: Anesthesiology Source Type: research

Efficacy and Safety of Transdermal Buprenorphine versus Oral Tramadol/Acetaminophen in Patients with Persistent Postoperative Pain after Spinal Surgery.
This study compared the efficacy and safety of buprenorphine transdermal system (BTDS) to oral tramadol/acetaminophen (TA) in Korean patients with persistent, moderate pain following spinal surgery. METHODS: Open-label, interventional, randomized multicenter study. Adults with persistent postoperative pain (Numeric Rating Scale [NRS] ≥ 4 at 14-90 days postsurgery) were enrolled. Patients received once-weekly BTDS (n = 47; 5 μg/h titrated to 20 μg/h) or twice-daily TA (n = 40; tramadol 37.5 mg/acetaminophen 325 mg, one tablet titrated to 4 tablets) for 6 weeks. The study compared pain reduction with BTDS...
Source: Pain Research and Management - October 24, 2017 Category: Anesthesiology Authors: Lee JH, Kim JH, Kim JH, Kim HS, Min WK, Park YS, Lee KY, Lee JH Tags: Pain Res Manag Source Type: research