Polyphasic characterization and genomic insights into Nocardioides turkmenicus sp. nov. isolated from a desert soil
Antonie Van Leeuwenhoek. 2024 Jan 23;117(1):25. doi: 10.1007/s10482-023-01920-2.ABSTRACTStrain KC13T, a novel desert-adapted, non-motile, Gram-stain-positive, rod-shaped, aerobic bacterium, was isolated from a soil sample collected from the Karakum Desert, Turkmenistan and characterised by a polyphasic approach. Phylogenetic analysis based on 16S rRNA sequences revealed that strain KC13T was a member of the genus Nocardioides, and formed a distinct cluster with Nocardioides luteus DSM 43366T (99.3% sequence identity), Nocardioides albus DSM 43109T (98.9%), Nocardioides panzhihuensis DSM 26487T (98.3%) and Nocardioides albe...
Source: Antonie van Leeuwenhoek - January 23, 2024 Category: Microbiology Authors: Hayrettin Saygin Kiymet Guven Demet Cetin Nevzat Sahin Source Type: research

Rhupus syndrome in children: A multi-center retrospective cohort study and literature review
CONCLUSION: Our study is the largest cohort in the literature evaluating pediatric rhupus cases. Most of the pediatric patients had polyarticular, asymmetric, and erosive arthritis, as well as organ involvements associated with SLE, including the skin, hematological system, and kidney.PMID:38226485 | DOI:10.1177/09612033231226353 (Source: Lupus)
Source: Lupus - January 16, 2024 Category: Rheumatology Authors: Seher Sener Ezgi Deniz Batu Sezgin Sahin Deniz Gezgin Yildirim Miray Kisla Ekinci Hakan Kisaoglu Yasin Karali Selcan Demir Ummusen Kaya Akca Aybuke Gunalp Seyma Turkmen Gulsah Kavrul Kayaalp Ceyda Arslanoglu Ruya Torun Ozge Basaran Aysenur Pac Kisaarslan Source Type: research

Assessment of microcirculatory alteration by a vascular occlusion test using near-infrared spectroscopy in pediatric cardiac surgery: effect of cardiopulmonary bypass
CONCLUSION: Microcirculatory function can assessed using VOT with forearm Near-infrared spectroscopy derived variables during cardiopulmonary bypass in pediatric cardiac surgery. Noninvasive assessment of microcirculatory perfusion during cardiopulmonary bypass can further help evaluate and improve circulatory support techniques.TRIAL REGISTRATION: The research Project was registered at ClinicalTrials.gov (NCT06191913).PMID:38217402 | DOI:10.1080/17434440.2024.2306155 (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - January 13, 2024 Category: Medical Devices Authors: Omer Faruk Savluk Abdullah Arif Yilmaz Yasemin Yavuz Seda Arisut Fatma Ukil Isildak Aysu Turkmen Karaagac Baburhan Ozbek Nihat Cine Eylem Tuncer Hakan Ceyran Source Type: research

Botanical description, phytochemical constituents, ethnobotany, traditional medicinal use, and pharmacological activities of < em > Stachys lavandulifolia < /em > Vahl
Nat Prod Res. 2024 Jan 8:1-15. doi: 10.1080/14786419.2023.2301004. Online ahead of print.ABSTRACTStachys lavandulifolia Vahl known as "mountain tea", is a perennial flowering plant belonging to the Lamiaceae family and is widespread in Iran, Armenia, Azerbaijan, Iraq, Turkey and Turkmenistan. S. lavandulifolia is widely used in traditional medicine for its analgesic, anti-inflammatory and anxiolytic properties. This plant has different chemical compounds classes including terpenoids, iridoids, flavonoids and phenylethanoids that have been isolated from the aerial parts of it. This review covers the plant botany, traditiona...
Source: Natural Product Research - January 8, 2024 Category: Biochemistry Authors: Dara Dastan Christopher Dobie Reza Zadali Mouhamad Hassan Pourrashid Danielle Skropeta Mansour Miran Source Type: research

Botanical description, phytochemical constituents, ethnobotany, traditional medicinal use, and pharmacological activities of < em > Stachys lavandulifolia < /em > Vahl
Nat Prod Res. 2024 Jan 8:1-15. doi: 10.1080/14786419.2023.2301004. Online ahead of print.ABSTRACTStachys lavandulifolia Vahl known as "mountain tea", is a perennial flowering plant belonging to the Lamiaceae family and is widespread in Iran, Armenia, Azerbaijan, Iraq, Turkey and Turkmenistan. S. lavandulifolia is widely used in traditional medicine for its analgesic, anti-inflammatory and anxiolytic properties. This plant has different chemical compounds classes including terpenoids, iridoids, flavonoids and phenylethanoids that have been isolated from the aerial parts of it. This review covers the plant botany, traditiona...
Source: Natural Product Research - January 8, 2024 Category: Biochemistry Authors: Dara Dastan Christopher Dobie Reza Zadali Mouhamad Hassan Pourrashid Danielle Skropeta Mansour Miran Source Type: research

EE573 Economic Burden of Chronic Kidney Disease with Type 2 Diabetes in Turkiye
The aim of this study is to calculate the costs of chronic kidney disease(CKD) with type 2 diabetes (T2DM) according to the stages in Turkiye. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: M. Kurnaz, A. Y ıldız, A. Oguz, E. Turkmen, A. Karatas, T. Buyukisik, F. Öztürk, S. Okcun, Y. Erkut, G. Kockaya Source Type: research

Arteriovenous malformation presenting as a lip swelling
Key Clinical MessageArteriovenous malformations (AVM) are extremely rare on the face and especially on the lip. Lip can be more easily exposed to traumas due to their anatomical location. Especially superficial AV malformations are very susceptible to trauma and can bleed very seriously after being exposed to such effects. AVMs management generally based on their hemodynamic characteristics and growth modalities. The surgical treatment requires elaborate planning and multidisciplinary approach. When evaluating a mass with a clinical manifestation of lip swelling, ruling out a vascular anomaly before any intervention is als...
Source: Clinical Case Reports - November 20, 2023 Category: General Medicine Authors: Ashok Kumar Ariboyina, Ozgur Tatli, Lakshmi Goriparthi, Narendra Achanta, Suresh Kumar Thirumoothy, Suha Turkmen Tags: CASE REPORT Source Type: research

Evaluation of the therapeutic effects of arbutin on cisplatin-induced ovarian toxicity in rats through endoplasmic reticulum stress and Nrf2 pathway
This study aimed to evaluate the therapeutic effect of ARB against CP-related ovototoxicity by including nuclear factor erythroid 2-related factor 2 (Nrf2) pathway in rats for the first time. Rats treated one dose of CP (5 mg/kg) on the first day, followed by ARB (5 and 10 mg/kg) for three days. Serum reproductive hormone levels were determined using ELISA kits. Oxidative stress (OS), inflammation, endoplasmic reticulum stress (ERS) and apoptosis markers in ovarian tissue were also determined colorimetrically. In addition, how CP affects Nrf2 pathway and the effect of ARB on this situation were also addressed. ARB treatmen...
Source: Reproductive Biology - November 17, 2023 Category: Reproduction Medicine Authors: Elif Ayazoglu Demir Ahmet Mentese Zeynep Sagnak Yilmaz Nihal Turkmen Alemdar Selim Demir Yuksel Aliyazicioglu Source Type: research

Gentisic acid ameliorates cisplatin-induced reprotoxicity through suppressing endoplasmic reticulum stress and upregulating Nrf2 pathway
Tissue Cell. 2023 Oct 24;85:102256. doi: 10.1016/j.tice.2023.102256. Online ahead of print.ABSTRACTReproductive toxicity is a serious side effect of cisplatin (CP) chemotherapy. Gentisic acid (GTA) is a phenolic acid with strong antioxidant properties. Here, we aimed to determine therapeutic effect of GTA against CP-induced testicular toxicity in rats for the first time. Male Sprague-Dawley rats received a single dose of CP (5 mg/kg; intraperitoneal) and treated with GTA (1.5 and 3 mg/kg; intraperitoneal; 3 consecutive days). The levels of oxidative stress (OS), inflammation, endoplasmic reticulum stress (ERS) and apoptosi...
Source: Tissue and Cell - November 2, 2023 Category: Cytology Authors: Ahmet Mentese Selim Demir Sevdegul Aydin Mungan Nihal Turkmen Alemdar Elif Ayazoglu Demir Yuksel Aliyazicioglu Source Type: research

Gentisic acid ameliorates cisplatin-induced reprotoxicity through suppressing endoplasmic reticulum stress and upregulating Nrf2 pathway
Tissue Cell. 2023 Oct 24;85:102256. doi: 10.1016/j.tice.2023.102256. Online ahead of print.ABSTRACTReproductive toxicity is a serious side effect of cisplatin (CP) chemotherapy. Gentisic acid (GTA) is a phenolic acid with strong antioxidant properties. Here, we aimed to determine therapeutic effect of GTA against CP-induced testicular toxicity in rats for the first time. Male Sprague-Dawley rats received a single dose of CP (5 mg/kg; intraperitoneal) and treated with GTA (1.5 and 3 mg/kg; intraperitoneal; 3 consecutive days). The levels of oxidative stress (OS), inflammation, endoplasmic reticulum stress (ERS) and apoptosi...
Source: Tissue and Cell - November 2, 2023 Category: Cytology Authors: Ahmet Mentese Selim Demir Sevdegul Aydin Mungan Nihal Turkmen Alemdar Elif Ayazoglu Demir Yuksel Aliyazicioglu Source Type: research

Gentisic acid ameliorates cisplatin-induced reprotoxicity through suppressing endoplasmic reticulum stress and upregulating Nrf2 pathway
Tissue Cell. 2023 Oct 24;85:102256. doi: 10.1016/j.tice.2023.102256. Online ahead of print.ABSTRACTReproductive toxicity is a serious side effect of cisplatin (CP) chemotherapy. Gentisic acid (GTA) is a phenolic acid with strong antioxidant properties. Here, we aimed to determine therapeutic effect of GTA against CP-induced testicular toxicity in rats for the first time. Male Sprague-Dawley rats received a single dose of CP (5 mg/kg; intraperitoneal) and treated with GTA (1.5 and 3 mg/kg; intraperitoneal; 3 consecutive days). The levels of oxidative stress (OS), inflammation, endoplasmic reticulum stress (ERS) and apoptosi...
Source: Tissue and Cell - November 2, 2023 Category: Cytology Authors: Ahmet Mentese Selim Demir Sevdegul Aydin Mungan Nihal Turkmen Alemdar Elif Ayazoglu Demir Yuksel Aliyazicioglu Source Type: research

Saiga (Saiga tatarica) conservation strategy in Kazakhstan
Braz J Biol. 2023 Oct 13;83:e275397. doi: 10.1590/1519-6984.275397. eCollection 2023.ABSTRACTThe saiga antelope (Saiga tatarica) is a living symbol of the Eurasian steppes. Even in the recent past, its total number exceeded a million heads. As a commercial species, it was a source of inexpensive meat and skins for suede. The natural world range of saiga in Eurasia covers the steppe and desert ecosystems of Kazakhstan, Uzbekistan, Turkmenistan, Mongolia, as well as Kalmykia and the Astrakhan region in the Russian Federation. It is divided into two subspecies: (Saiga tatarica tatarica) the nominal subspecies and (S.t.mongoli...
Source: Braz J Biol - October 18, 2023 Category: Biology Authors: A T Serikbayeva D Sh Akimzhanov Zh A Iskakova Zh Karagoishin M T Akoyev T N Dauletaliyev O A Baitanayev Source Type: research

Saiga (Saiga tatarica) conservation strategy in Kazakhstan
Braz J Biol. 2023 Oct 13;83:e275397. doi: 10.1590/1519-6984.275397. eCollection 2023.ABSTRACTThe saiga antelope (Saiga tatarica) is a living symbol of the Eurasian steppes. Even in the recent past, its total number exceeded a million heads. As a commercial species, it was a source of inexpensive meat and skins for suede. The natural world range of saiga in Eurasia covers the steppe and desert ecosystems of Kazakhstan, Uzbekistan, Turkmenistan, Mongolia, as well as Kalmykia and the Astrakhan region in the Russian Federation. It is divided into two subspecies: (Saiga tatarica tatarica) the nominal subspecies and (S.t.mongoli...
Source: Braz J Biol - October 18, 2023 Category: Biology Authors: A T Serikbayeva D Sh Akimzhanov Zh A Iskakova Zh Karagoishin M T Akoyev T N Dauletaliyev O A Baitanayev Source Type: research

Saiga (Saiga tatarica) conservation strategy in Kazakhstan
Braz J Biol. 2023 Oct 13;83:e275397. doi: 10.1590/1519-6984.275397. eCollection 2023.ABSTRACTThe saiga antelope (Saiga tatarica) is a living symbol of the Eurasian steppes. Even in the recent past, its total number exceeded a million heads. As a commercial species, it was a source of inexpensive meat and skins for suede. The natural world range of saiga in Eurasia covers the steppe and desert ecosystems of Kazakhstan, Uzbekistan, Turkmenistan, Mongolia, as well as Kalmykia and the Astrakhan region in the Russian Federation. It is divided into two subspecies: (Saiga tatarica tatarica) the nominal subspecies and (S.t.mongoli...
Source: Braz J Biol - October 18, 2023 Category: Biology Authors: A T Serikbayeva D Sh Akimzhanov Zh A Iskakova Zh Karagoishin M T Akoyev T N Dauletaliyev O A Baitanayev Source Type: research

Saiga (Saiga tatarica) conservation strategy in Kazakhstan
Braz J Biol. 2023 Oct 13;83:e275397. doi: 10.1590/1519-6984.275397. eCollection 2023.ABSTRACTThe saiga antelope (Saiga tatarica) is a living symbol of the Eurasian steppes. Even in the recent past, its total number exceeded a million heads. As a commercial species, it was a source of inexpensive meat and skins for suede. The natural world range of saiga in Eurasia covers the steppe and desert ecosystems of Kazakhstan, Uzbekistan, Turkmenistan, Mongolia, as well as Kalmykia and the Astrakhan region in the Russian Federation. It is divided into two subspecies: (Saiga tatarica tatarica) the nominal subspecies and (S.t.mongoli...
Source: Braz J Biol - October 18, 2023 Category: Biology Authors: A T Serikbayeva D Sh Akimzhanov Zh A Iskakova Zh Karagoishin M T Akoyev T N Dauletaliyev O A Baitanayev Source Type: research