The treatment of periprosthetic joint infection: safety and efficacy of two stage versus one stage exchange arthroplasty.
THE TREATMENT OF PERIPROSTHETIC JOINT INFECTION: SAFETY AND EFFICACY OF TWO STAGE VERSUS ONE STAGE EXCHANGE ARTHROPLASTY. Expert Rev Med Devices. 2020 Feb 26;: Authors: Palmer JR, Pannu TS, Villa JM, Manrique J, Riesgo AM, Higuera CA Abstract INTRODUCTION: Periprosthetic joint infection (PJI) remains one of the most dreaded and challenging complications in adult reconstruction. While primary total joint arthroplasty is one of the most successful surgeries in medicine, revisions secondary to infections do not hold as well. As the number of primary procedures increases, so will infections. In North Ameri...
Source: Expert Review of Medical Devices - February 28, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Histopathologic and physiologic effect of bifurcation stenting: current status and future prospects.
Authors: Cornelissen A, Guo L, Sakamoto A, Jinnouchi H, Sato Y, Kuntz S, Kawakami R, Mori M, Fernandez R, Fuller D, Gadhoke N, Kolodgie FD, Surve D, Romero ME, Virmani R, Finn AV Abstract Introduction: Coronary bifurcation lesions are involved in up to 20% of all percutaneous coronary interventions (PCI). However, bifurcation lesion intervention is associated with a high complication rate, and optimal treatment of coronary bifurcation is an ongoing debate.Areas covered: Both different stenting techniques and a variety of devices have been suggested for bifurcation treatment, including the use of conventional corona...
Source: Expert Review of Medical Devices - February 28, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Device profile of the Coala Heart Monitor for remote monitoring of the heart rhythm: overview of its efficacy.
Authors: Insulander P, Carnlöf C, Schenck-Gustafsson K, Jensen-Urstad M Abstract Introduction: Several handheld thumb ECG devices for on-demand recording of heart rhythm have become available lately. These can be used both by health-care providers and purchased by laypersons for private use.Area covered: This profile describes the Coala Heart Monitor. This device differs from other handheld ECG monitors in three aspects: 1) it records both thumb and chest ECGs, 2) it uses both RR-dispersion and P-wave morphology for detecting atrial fibrillation, and 3) in synchronization with the chest ECG, it also records he...
Source: Expert Review of Medical Devices - February 28, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Recent advances in devices for minimally invasive aortic valve replacement.
Authors: Lamelas J, Alnajar A Abstract Introduction: Aortic valve disease is the most common valvular heart disease. Aortic valve replacement (AVR) is the treatment of choice for aortic valve stenosis (AS). Multiple options have been developed to treat AS, corresponding to the steadily growing AVR case volume. The increased adoption of minimally invasive aortic valve replacement (mini-AVR) techniques, despite being technically challenging, is reflected in its advantageous outcomes. Continuous device development can add a critical value to the technical expertise and advance the proficiency of mini-AVR.Areas covered...
Source: Expert Review of Medical Devices - February 28, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Particulated juvenile articular cartilage allograft transplantation for osteochondral lesions of the knee and ankle.
Authors: Wixted CM, Dekker TJ, Adams SB Abstract Introduction: Osteochondral lesions have been challenging to treat due to the limited regenerative capacity of native hyaline cartilage. Although surgical options are available, a newer technique, Particulated Juvenile Cartilage Allograft Transplantation (PJCAT) has shown promise for lesions of the knee and ankle. Short-term studies have been encouraging of its use, but there is still limited evidence of its long-term durability.Areas covered: This review will summarize the surgical options currently available for osteochondral lesions, outline the indications and co...
Source: Expert Review of Medical Devices - February 26, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Diagnosis, treatment & management of prosthetic valve thrombosis: the key considerations.
Diagnosis, treatment & management of prosthetic valve thrombosis: the key considerations. Expert Rev Med Devices. 2020 Feb 21;: Authors: Gündüz S, Kalçık M, Gürsoy MO, Güner A, Özkan M Abstract Introduction: Prosthetic heart valve thrombosis is a life-threatening complication after valve replacement surgery. Although subtherapeutic anticoagulation is the main cause, there are many other conventional and esoteric predisposing factors.Areas covered: The etiopathogenesis, diagnosis and management of prosthetic heart valve thrombosis with particular focus on conventiona...
Source: Expert Review of Medical Devices - February 24, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Device profile of the Wingspan Stent System for the treatment of intracranial atherosclerotic disease: overview of its safety and efficacy.
Authors: Barnard ZR, Alexander MJ Abstract Introduction: This Wingspan Stent is a self-expanding, laser-cut, nitinol stent designed for the treatment of severe symptomatic intracranial artery stenosis to be used in conjunction with the Gateway angioplasty balloon. This review will describe the technical features of the stent, its composition, design, and functional characteristics, as well as an overview of its safety and efficacy.Areas covered: The engineering and manufacturing specifications are described for the stent. A systematic review of the literature from 2005 to 2019 is performed to define the safety prof...
Source: Expert Review of Medical Devices - February 21, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Ablation for the treatment of Brugada syndrome: current status and future prospects.
Authors: Rizzo A, de Asmundis C, Brugada P, La Meir M, Chierchia GB Abstract Introduction: Brugada syndrome (BrS) is an inherited disease characterized by an increased risk of sudden cardiac death (SCD). Therapeutic options in symptomatic patients are limited to implantable cardioverter defibrillator (ICD) and quinidine, but catheter ablation of the right ventricular outflow tract (RVOT) offers a potential cure. Different ablation strategies have been used to treat patients with symptomatic Brugada syndrome. Epicardial radiofrequency substrate ablation of the RVOT/right ventricle (RV) has emerged as a promising too...
Source: Expert Review of Medical Devices - January 30, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

How viable is pre-surgery weight reduction for the reduction of periprosthetic joint infection risk after total joint arthroplasty?
Authors: Yayac M, Aggarwal R, Parvizi J PMID: 31986924 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - January 30, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Pulsed radiofrequency for low-back pain and sciatica.
Authors: Napoli A, Alfieri G, Scipione R, Andrani F, Leonardi A, Catalano C PMID: 31973587 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - January 26, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

How can multidisciplinary management with remote monitoring improve the outcome of patients with chronic cardiac diseases?
Authors: Scalvini S, Comini L, Bernocchi P PMID: 31976782 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - January 26, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Device profile of different paclitaxel-coated balloons: Neuro Elutax SV, Elutax "3" Neuro and SeQuent Please NEO for the treatment of symptomatic intracranial high-grade stenosis: overview of their feasibility and safety.
Device profile of different paclitaxel-coated balloons: Neuro Elutax SV, Elutax "3" Neuro and SeQuent Please NEO for the treatment of symptomatic intracranial high-grade stenosis: overview of their feasibility and safety. Expert Rev Med Devices. 2020 Jan 21;: Authors: Gruber P, Remonda L Abstract Introduction: Intracranial atherosclerotic disease (ICAD) is highly prevalent and probably the most common cause of stroke worldwide. Despite best medical treatment (BMT), the rate of recurrent stroke in symptomatic ICAD patients is elevated, especially in those with high-grade stenosis. Thus, altern...
Source: Expert Review of Medical Devices - January 23, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

MR neurography of the brachial plexus in adult and pediatric age groups: evolution, recent advances, and future directions.
Authors: Mazal AT, Faramarzalian A, Samet JD, Gill K, Cheng J, Chhabra A Abstract Introduction: MR neurography (MRN) of the brachial plexus has emerged in recent years as a sensitive and specific modality for the identification of brachial plexopathies in pediatric and adult populations. While clinical differentiation of brachial plexopathy from cervical spine-related radiculopathy or nerve injury has long relied upon nonspecific physical exam and electrodiagnostic testing modalities, MRN now permits detailed interrogation of peripheral nerve anatomy and pathology, as well as assessment of surrounding soft tissues ...
Source: Expert Review of Medical Devices - January 23, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Osseointegrated prostheses for the rehabilitation of amputees (OPRA): results and clinical perspective.
Authors: Hoyt BW, Walsh SA, Forsberg JA Abstract Introduction: Patients who undergo extremity amputation have historically used socket prosthetics to ambulate and perform daily functions; however, these prosthetics can be limited by poor terminal control and wear issues. In patients who have difficulty wearing their prostheses or with upper extremity amputations, osseointegrated implants may offer better function and quality of life. The Osseointegrated Prostheses for the Rehabilitation of Amputees (OPRA) was the first such device to become commercially available. Clinical trials have demonstrated benefit in patien...
Source: Expert Review of Medical Devices - January 16, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Catheter Directed Interventions for pulmonary embolism: current status and future prospects.
We present a contemporary review summarizing the different catheter directed interventions currently available for acute PE, their indications, technical considerations, clinical effectiveness, complication rates and long-term outcomes.Expert opinion: For intermediate high-risk PE patients without a contraindication for thrombolysis, CDIs should be considered in patients at risk for clinical decompensation. For high risk PE patients with a major contraindication to thrombolytic therapy, suction thrombectomy can be considered in places with appropriate clinical and technical expertise. PMID: 31937150 [PubMed - as suppli...
Source: Expert Review of Medical Devices - January 16, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Topical negative pressure wound therapy: emerging devices and techniques.
Authors: Horch RE, Ludolph I, Müller-Seubert W, Zetzmann K, Hauck T, Arkudas A, Geierlehner A Abstract INTRODUCTION: The treatment of chronic wounds constitutes a massive financial burden to society and our health care system. Therefore, efficient wound care is of great importance to all kind of medical fields. The implementation and modification of negative pressure wound therapy can be seen as a major improvement on wound healing. Many different NPWT applications evolved trying to address various wound etiologies.Areas covered: This review aims to give an overview of various NPWT applications, show its effec...
Source: Expert Review of Medical Devices - January 12, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Recent advances in patient selection and devices for transcatheter edge-to-edge mitral valve repair in heart failure.
Authors: Orban M, Lüsebrink E, Braun D, Stocker TJ, Bagaev E, Hagl C, Näbauer M, Massberg S, Orban M, Hausleiter J Abstract Introduction: Heart failure (HF) and severe mitral regurgitation (MR) are mutually dependent. Secondary MR is a consequence of chronic heart failure with reduced left ventricular ejection fraction (HFrEF) and left ventricular (LV) dilatation. Severe MR worsens prognosis and accelerates LV dilatation as well as decline in LV ejection fraction. Interventional therapies have changed clinical practice for HF patients with secondary MR.Areas covered: In this review we summarize the availa...
Source: Expert Review of Medical Devices - January 12, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Devices for minimally-invasive microdiscectomy: current status and future prospects.
Authors: Ahn Y Abstract Introduction: The current gold standard technique for lumbar disc herniation (LDH) is open lumbar microdiscectomy. The use of a tubular retractor system in the microdiscectomy technique can minimize tissue trauma by muscle-splitting sequential dilation during the surgical approach. This review aimed to describe the devices and surgical procedure of this minimally invasive microdiscectomy (MI-MD) and to discuss the pros and cons of the use of tubular retractors.Areas covered: Published medical literatures were extensively reviewed to summarize the practical devices and techniques related to t...
Source: Expert Review of Medical Devices - December 24, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Robotic totally endoscopic coronary artery bypass grafting: current status and future prospects.
Authors: Bonatti J, Wallner S, Winkler B, Grabenwoeger M Abstract Introduction: Totally endoscopic coronary artery bypass grafting (TECAB) can only be performed in a reproducible manner using robotic technology. This operation has been developed for more than 20 years seeing three generations of surgical robots. TECAB can be carried out beating heart but also on the arrested heart. Single and multiple grafts can be placed and TECAB can be combined with percutaneous coronary intervention in hybrid procedures.Areas covered: This review outlines indications for the procedure, the surgical technique, and the postoperat...
Source: Expert Review of Medical Devices - December 14, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Τηε afx unibody bifurcated unibody aortic endograft for the treatment of Abdominal Aortic aneurysms: current evidence and future perspectives.
Τηε afx unibody bifurcated unibody aortic endograft for the treatment of Abdominal Aortic aneurysms: current evidence and future perspectives. Expert Rev Med Devices. 2019 Dec 13;: Authors: Georgakarakos E, Ioannidis G, Koutsoumpelis A, Papatheodorou N, Argyriou C, Spanos K, Giannoukas AD, Georgiadis GS Abstract Introduction: AFX is a bifurcated unibody aortic endograft for the treatment of Abdominal Aortic aneurysms. It consists of an inner metallic endoskeleton with multiple metallic struts covered by a polytetrafluoroethylene graft fabric. The endoskeleton is sutured to the outer fab...
Source: Expert Review of Medical Devices - December 14, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Accuracy of a blood glucose monitoring system that recognizes insufficient sample blood volume and allows application of more blood to the same test strip.
Authors: Harrison B, Brown D Abstract Background: Self-monitoring of blood glucose (SMBG) can play a key role in diabetes management. The CONTOUR®NEXT ONE (Ascensia Diabetes Care, Parsippany, NJ, USA) blood glucose monitoring system (BGMS) has been developed for use with CONTOUR®NEXT test strips. The meter connects to the CONTOUR™ Diabetes application on a mobile device, and the Second-Chance® sampling feature recognizes insufficient sample volume, prompting the patient to apply more blood to the same strip if needed (sample re-application).Research design and methods: Two studies evaluated CONTOU...
Source: Expert Review of Medical Devices - December 13, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Diagnosis and Management of Implant Debris-Associated Inflammation.
Authors: Goodman SB, Gallo J, Gibon EFD, Takagi M Abstract Introduction: Total joint replacement is one of the most common, safe and efficacious operations in all of surgery. However, one major long-standing and unresolved issue is the adverse biological reaction to byproducts of wear from the bearing surfaces and modular articulations. These inflammatory reactions are mediated by the innate and adaptive immune systems.Areas Covered: We review the etiology and pathophysiology of implant debris-associated inflammation, the clinical presentation and detailed work-up of these cases, and the principles and outcomes of ...
Source: Expert Review of Medical Devices - December 9, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Future potential of engineered heart tissue patches for repairing the damage caused by heart attacks.
Authors: Jabbour RJ, Owen TJ, Pandey P, Harding SE PMID: 31809201 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - December 7, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Colonic stents for malignant bowel obstruction: current status and future prospects.
Authors: Ormando VM, Palma R, Fugazza A, Repici A Abstract Introduction: Although more than two decades are already passed from the first description of this technique, the debate remains open on the role of self-expanding metal stents (SEMS) placement in the management of malignant bowel obstruction (MBO). According to most recent data, SEMS placement is considered a safe and effective alternative treatment as a bridge to surgery(BTS). In addition, stent placement should be considered as primary option for palliative treatment of obstructing cancer.Areas covered: Current status, indication, technique, oncological ...
Source: Expert Review of Medical Devices - November 30, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Robotic navigation during spine surgery.
Authors: Zhang Q, Han XG, Xu YF, Fan MX, Zhao JW, Liu YJ, He D, Tian W Abstract Introduction: Potential complications associated with screw malposition may result in neurological deficits or vascular injuries. Spine surgery has significantly developed under the assistance of technological progress. The advantages of applying robotic technology in spine surgery include the possibility of improving screw accuracy, reducing complications, decreasing fluoroscopy use.Areas covered: We critically evaluated the current literature on the radiographic and clinical outcomes of robotic-assisted spine surgery, including accura...
Source: Expert Review of Medical Devices - November 30, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Pediatric ventricular assist devices: what are the key considerations and requirements?
Authors: Hetzer R, Javier MFDM, Javier Delmo EM Abstract Introduction: The development of ventricular assist devices (VADs) have enabled myocardial recovery and improved patient survival until heart transplantation. However, device options remain limited for children and lag in development.Areas covered: This review focuses on the evolution of pediatric VADs in becoming an accepted treatment option in advanced heart failure, discusses the classification of VADs available for children, i.e. types of pumps and duration of support, and defines implantation indications and explantation criteria with attendant complicat...
Source: Expert Review of Medical Devices - November 30, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Sleep assessment devices: types, market analysis, and a critical view on accuracy and validation.
Authors: Ibáñez V, Silva J, Navarro E, Cauli O Abstract Introduction: Sleep assessment devices are essential for the detection, diagnosis, and monitoring of sleep disorders. This paper provides a state-of-the-art review and comparison of sleep assessment devices and a market analysis.Areas covered: Hardware devices are classified into contact and contactless devices. For each group, the underlying technologies are presented, paying special attention to their limitations. A systematic literature review has been carried out by comparing the most important validation studies of sleep tracking devices in ...
Source: Expert Review of Medical Devices - November 29, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Baroreflex activation therapy systems: current status and future prospects.
Authors: Seravalle G, Dell'Oro R, Grassi G Abstract Introduction: Resistant hypertension is characterized by an hyperadrenergic tone and by a neurohumoral activation. In this condition drug therapies are unable to obtain a good control of blood pressure and therefore need a contribution from non-pharmachological approach. To this aim it has been hypothesized that to lower blood pressure this could be obtained through stimulation of carotid baroreceptors and modulation of the adrenergic tone.Areas covered: several studies and trials have evaluated the safety and efficacy of two devices-based therapies and this revie...
Source: Expert Review of Medical Devices - November 29, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Device profile of the Heartware HVAD system as a bridge-to-transplantation in patients with advanced heart failure: overview of its safety and efficacy.
Authors: Mariani S, Hanke JS, Li T, Merzah AS, Chatterjee A, Deniz E, Haverich A, Schmitto JD, Dogan G Abstract Introduction: Heart failure (HF) is one of the rising problems in the contemporary society with growing incidences of end-stage HF. While heart transplantation (HT) is the gold standard treatment for end-stage HF, its availability is limited by the lack of heart donors. As a consequence, left ventricular assist devices (LVADs) are becoming key therapies as bridge to transplant (BTT) strategy to improve survival and outcomes.Areas covered: A significant advancement for wider applications of LVADs as BTT wa...
Source: Expert Review of Medical Devices - November 29, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Intra-rater and inter-rater reliability of cervical active range of movement in young asymptomatic adults using inertial sensors.
CONCLUSION: The data obtained in this study suggest that inertial sensors can be used in clinics due to their high intra- and inter-rater ICC (>0.80). Also, its low economic cost, easy handling, and various utilities make this tool a useful alternative in the measurement of cervical aROM. PMID: 31752559 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - November 24, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Risk factors, diagnosis and management of prosthetic joint infection after total hip arthroplasty.
Authors: Ahmed SS, Begum F, Kayani B, Haddad FS Abstract INTRODUCTION: Although a relatively rare complication, the incidence and prevalence of prosthetic joint infection (PJI) is certainly rising. This is mainly due to the number of arthroplasties performed each year and our ability to capture more cases. There is currently no consensus in the optimal diagnosis and management of the infected total hip arthroplasty. Various management techniques have been described in literature.Areas covered: We discuss and summarise the literature in diagnosing prosthetic joint infection (PJI) including next generation sequencing...
Source: Expert Review of Medical Devices - November 24, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Device profile of the NerivioTM for acute migraine treatment: overview of its efficacy and safety.
Authors: Rapoport AM, Lin T Abstract Introduction: Non-invasive neuromodulation devices represent an emerging field in the acute treatment of migraine. High efficacy, favorable safety profile, good tolerability and low cost are important factors for the desired shift to non-pharmacological treatments. This will have the potential to improve the quality of life of people with migraine and reduce the risk for adverse events and medication overuse headache (MOH).Areas covered: Nerivio™ (Theranica Bio-Electronics, Israel) is a novel FDA-cleared remote electrical neuromodulation (REN) device for acute treatment of...
Source: Expert Review of Medical Devices - November 21, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Virtual reality in the diagnostics and therapy of neurological diseases.
Authors: Słyk S, Zarzycki MZ, Kocwa-Karnaś A, Domitrz I Abstract Introduction: The use of Virtual Reality (VR) in neurology mainly concerns motor solutions. Such an approach is cost-effective and resource-effective. The aim of this work is to review and assess the effectiveness of proposed VR systems in order to diagnose and rehabilitate neurological patients with cognitive disorders.Areas covered: The existing analog neuropsychological tests lack ecological validity. The literature review revealed that VR solutions' biggest advantage is the possibility of assessing patients in everyday situations. Specific tasks...
Source: Expert Review of Medical Devices - November 20, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Augmenting mistakes: are augmented reality headsets in surgery a dead end?
Authors: Ferrari V, Carbone M, Condino S, Cutolo F PMID: 31725347 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - November 16, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

A review of pulmonary autograft external support in the Ross procedure.
This article reviews the incidence of pulmonary autograft dilatation, its risk factors and pathophysiology. The techniques of external pulmonary autograft support are discussed along with their respective advantages and limitations. Finally, future areas of research and developments are examined. EXPERT OPINION: The risk of autograft dilatation is mainly prevalent in patients with aortic regurgitation and a dilated aortic annulus. In these selected patients, an external support may prevent dilatation of the autograft. However, any permanent support potentially restricts autograft root motion, mitigating some of the adv...
Source: Expert Review of Medical Devices - October 31, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Optimizing fast first pass complete reperfusion in acute ischemic stroke - the BADDASS approach (BAlloon guide with large bore Distal access catheter with Dual Aspiration with Stent-retriever as Standard Approach).
Authors: Ospel JM, Volny O, Jayaraman M, McTaggart R, Goyal M Abstract Introduction: Endovascular therapy is the standard of care for acute ischemic stroke due to large vessel occlusions. The ultimate goal is to achieve fast first pass complete reperfusion, since delayed and/or incomplete reperfusion increases complication rates and costs and deteriorates patient outcome. Achieving optimal results can sometimes be challenging, particularly in patients with tortuous vessels. Several techniques have been described lately to optimize recanalization, including first line aspiration and various stent-retriever assisted ...
Source: Expert Review of Medical Devices - October 30, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Intraoperative storage of saphenous vein grafts in coronary artery bypass grafting.
Conclusions: Normal saline caused damage to vascular endothelium, loss of graft cell viability, and mediated cell damage; no evidence of damage or reactivity was observed in DuraGraft-exposed cells. PMID: 31648570 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - October 30, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

The evolution of stent grafts for endovascular repair of abdominal aortic aneurysms: how design changes affect clinical outcomes.
Authors: Bewley BR, Servais AB, Salehi P Abstract Introduction: Abdominal Aortic Aneurysm (AAA) is a potentially life-threatening condition caused by the ballooning of the patient's aortic wall. One treatment for this condition, Endovascular Aneurysm Repair (EVAR), has demonstrated a greater degree of safety in the short-term and has the potential to be more cost effective than its open surgical counterpart. Areas Covered: EVAR comes with the added risks of late-term failure, however, as the endografts are subject to displacement, loss of seal against the aortic wall, or failure to serve as a means of bypassing the...
Source: Expert Review of Medical Devices - October 30, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Leadless cardiac pacing systems: current status and future prospects.
Authors: Beurskens NEG, Breeman KTN, Dasselaar KJ, Meijer AC, Quast ABE, Tjong FVY, Knops RE Abstract Introduction: Permanent transvenous pacemaker therapy is an essential management option in patients with symptomatic bradyarrhythmias, but harbors a concomitant risk of serious complications. As most complications are lead- or pocket-related, intracardiac leadless pacemaker therapy has the potential to positively impact patient outcome. Since the first leadless pacemaker implant in 2012, many studies have been conducted to evaluate effectiveness, safety and applicability of this novel pacing approach. Areas covered...
Source: Expert Review of Medical Devices - October 30, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Clinical translation of the assets of biomedical engineering - a retrospective analysis with looks to the future.
Authors: Ren Y, Fagette PH, Hall CL, Broers H, Grainger DW, van der Mei HC, Busscher HJ Abstract Introduction: Biomedical-engineering (BME) plays a major role in modern medicine. Many BME-based assets have been brought to clinical translation in the 20th century, but translation currently stagnates. Here, we compare the impact of past and present scientific, economic and societal climates on the translation of BME-based assets, in order to provide the BME-community with incentives to address current stagnation. Areas covered: In the 20th century, W.J. Kolff brought kidney dialysis, the total artificial heart, artif...
Source: Expert Review of Medical Devices - October 30, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Recent developments on foaming mechanical and electronic techniques for the management of varicose veins.
Authors: Critello CD, Pullano SA, Matula TJ, de Franciscis S, Serra R, Fiorillo AS Abstract Introduction: Varicose veins are a common disease, causing significant impairment of quality of life to afflicted individuals. Conventional surgery has represented the traditional treatment for years, with significant post-operative complications. By the end of the 20th century, novel approaches had been developed to induce biochemical sclerosis into the treated vein in order to exclude it from blood circulation. Areas Covered: Foaming techniques for treatment of varicose veins, both clinically-approved methods and those und...
Source: Expert Review of Medical Devices - October 18, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Current approaches for treatment of coronary chronic occlusions.
Authors: Iannaccone G, Scarparo P, Wilschut J, Daemen J, den Dekker W, De Jaegere P, Zijlstra F, Van Mieghem NM, Diletti R Abstract Introduction Coronary chronic total occlusions (CTO) represent a challenging subset in interventional cardiology. Areas covered During the last decade, improvements in materials, techniques and meticulous pre-procedural lesion assessment have increased the success rate in CTO lesions. Several scores have been developed to address overall lesion evaluation and help select the most appropriate treatment strategy. In addition, specific algorithms such as the hybrid algorithm have been int...
Source: Expert Review of Medical Devices - October 10, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

The role of exercise haemodynamics in assessing patients with chronic heart failure and left ventricular assist devices.
Authors: Koshy A, Green T, Toms A, Cassidy S, Schueler S, Jakovljevic D, MacGowan GA Abstract Introduction: Chronic heart failure is characterised by reduced exercise capacity with symptoms often experienced during activity. Invasive exercise haemodynamics are not routinely performed unless patients undergo transplant or LVAD assessment, though now with readily available non-invasive devices, exercise haemodynamics are easily obtained. Our contention is that this is a valuable opportunity to acquire a more accurate measure of cardiac status in heart failure. Exercise haemodynamic measures such as cardiac power outp...
Source: Expert Review of Medical Devices - October 5, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Systematic review on gastric electrical stimulation in obesity treatment.
Authors: Maisiyiti A, Chen JD Abstract Introduction: Obesity is a very common public health problem worldwide. However, there is a lack of effective therapies. Only a small portion of patients with morbid obesity are accepting bariatric surgery as the last option due to the risks associated with invasive therapy. Areas covered: In this paper, we review an emerging weight loss treatment: gastric electrical stimulation (GES). The feasibility of GES as a potential therapy for obesity is introduced. Methodologies and parameters of GES are presented. Several GES methods for treating obesity and their effects on food int...
Source: Expert Review of Medical Devices - October 3, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Transcatheter aortic valve replacement: clinical safety and performance data.
Authors: van Baal JWPM, Roszek B, van Elk M, Geertsma RE Abstract Introduction: Patients with severe aortic stenosis and regurgitation who are inoperable or at high-risk for surgery can be treated with transcatheter aortic valve replacement (TAVR). The aim of this study was to provide a comprehensive overview of the literature of TAVR and reported clinical and performance outcomes. Areas covered: A total of 16 devices, described in 204 articles describing clinical and performance outcomes, were included. The most frequently observed outcome was 30-day mortality, ranging between 0-23%. Other commonly reported clinic...
Source: Expert Review of Medical Devices - October 1, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

The future potential of the Stentrode.
Authors: John SE, Grayden DB, Yanagisawa T PMID: 31568731 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - October 1, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Carbon nanomaterials: a new way against tuberculosis.
Authors: De Maio F, Palmieri V, De Spirito M, Delogu G, Papi M Abstract Introduction: Tuberculosis (TB) remains one of the most alarming worldwide infectious disease primarily in low-income countries, where the infection shows a higher and unvaried prevalence. In the last years, the emergence and spread of Mycobacterium tuberculosis (Mtb) strains resistant to first-line anti-TB drugs are the cause of major concern and prompted the implementation of new treatments, including the development of new drugs and the repurposing of old ones. Areas covered: In this review, we discuss solutions against TB based on nanomater...
Source: Expert Review of Medical Devices - September 27, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

MiniMed 670G Hybrid Closed Loop Artificial Pancreas System for the Treatment of Type 1 Diabetes Mellitus: Overview of Its Safety and Efficacy.
Authors: Saunders A, Messer LH, Forlenza GP Abstract Introduction: Automated insulin delivery for people with type 1 diabetes has been a major goal in the diabetes technology field for many years. While a fully automated system has not yet been accomplished, the MiniMed™ 670G artificial pancreas (AP) system is the first commercially available insulin pump that automates basal insulin delivery, while still requiring user input for insulin boluses. Determining the safety and efficacy of this system is essential to the development of future devices striving for more automation. Areas Covered: This review will pr...
Source: Expert Review of Medical Devices - September 23, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

A review of medical image detection for cancers in digestive system based on artificial intelligence.
Authors: Xu J, Jing M, Wang S, Yang C, Chen X Abstract Introduction: At present, cancer imaging examination relies mainly on manual reading of doctors, which requests a high standard of doctors' professional skills, clinical experience and concentration. However, the increasing amount of medical imaging data has brought more and more challenges to radiologists. The detection of digestive system cancer (DSC) based on artificial intelligence (AI) can provide a solution for automatic analysis of medical images and assist doctors to achieve high-precision intelligent diagnosis of cancers. Areas covered: The main goal o...
Source: Expert Review of Medical Devices - September 20, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Does antimicrobial coating and impregnation of urinary catheters prevent catheter-associated urinary tract infection? A review of clinical and preclinical studies.
Authors: Majeed A, Sagar F, Latif A, Hassan H, Iftikhar A, Darouiche RO, Mohajer MA Abstract Introduction: Catheter-associated urinary tract infection (CAUTI) is one of the most common nosocomial infections in hospitals, accounting for 36% of all health care-associated infections. Areas Covered: We aimed to address the potential impact of antimicrobial coating of catheter materials for the prevention of CAUTI and to analyze the progress made in this field. We conducted literature searches in the PubMed, Embase, and Cochrane Library databases, and found 578 articles. Data from 60 articles in either the preclinical o...
Source: Expert Review of Medical Devices - September 4, 2019 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research