Laryngoscopes for difficult airway scenarios: a comparison of the available devices.
Authors: Szarpak L Abstract INTRODUCTION: According to the American Society of Anesthesiologists, the incidence of difficult intubation in the operating room is 1.2-3.8%; however, in emergency conditions, this rate is higher and reaches even 5.3%. Successful emergency airway management is an essential component of the modern practice of medicine. Areas covered: The aim of the study is to review the literature regarding different devices used to perform endotracheal intubation (Macintosh, Miller, and McCoy laryngoscopes; ETView, GlideScope, TruView, Airtraq, McGrath MAC, Pentax AWS, Trachlight, Shikani, and Bullard)...
Source: Expert Review of Medical Devices - August 15, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Shields and garb for decreasing radiation exposure in the cath lab.
Authors: Karatasakis A, Brilakis ES Abstract INTRODUCTION: Decreasing radiation exposure of the cardiac catheterization laboratory staff is critical for minimizing radiation-related adverse outcomes and can be accomplished by decreasing patient dose and by shielding. Areas covered: shielding from ionizing radiation can be achieved with architectural, equipment-mounted, and disposable shields, as well as with personal protective equipment. Expert commentary: Radiation protective aprons are the most commonly used personal protective equipment and provide robust radiation protection but can cause musculoskeletal strai...
Source: Expert Review of Medical Devices - August 11, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Randomised comparison of the Baska FESS mask and the LMA Supreme in different head and neck positions.
Authors: Foo LL, Shariffuddin II, Chaw SH, Lee PK, Lee CE, Chen YS, Chan L Abstract BACKGROUND: The Baska FESS mask is a new supraglottic airway designed for head and neck procedures. This prospective, randomized controlled trial compared the oropharyngeal leak pressure (OLP) of the Baska FESS mask with the LMA Supreme in different head and neck positions. METHODS: One hundred patients undergoing elective surgery were recruited. OLP was compared in supine position, 45° lateral rotation, 45° neck extension and 30° neck flexion. Glottic view, insertion time, ease of insertion, number of attempts, ease...
Source: Expert Review of Medical Devices - August 11, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Current devices used for the monitoring of injection pressure during peripheral nerve blocks.
Authors: Gadsden J Abstract INTRODUCTION: Peripheral nerve blocks are generally safe. However, there is a small but real associated risk of needle-related complications such as nerve injury. Nerve injury has been associated with high pressure injections in animals, and some data supports the use of monitors to limit injection pressure during these procedures. Areas covered: A literature search for articles with keywords 'injection,' 'pressure,' and 'nerve' was conducted. All currently available devices designed to monitor injection pressure and/or prevent high pressure injections were reviewed. There are three clas...
Source: Expert Review of Medical Devices - August 8, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Recent advances in devices for vagus nerve stimulation.
Authors: Mertens A, Raedt R, Gadeyne S, Carrette E, Boon P, Vonck K Abstract INTRODUCTION: Vagus nerve stimulation (VNS) has become a valuable treatment option for refractory epilepsy and depression. To improve clinical efficacy and minimize side effects, novel device technology for vagus nerve stimulation is under development and investigation. Areas covered: For epilepsy, the AspireSR® and SenTiva™ VNS therapy systems are the 2 most recently developed VNS devices. These novel devices have implemented a closed-loop approach and contain a cardiac based seizure detection algorithm. The mechanism of action ...
Source: Expert Review of Medical Devices - August 4, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Identifying and addressing the limitations of EVAR technology.
Authors: Belvroy VM, Houben IB, Trimarchi S, Patel HJ, Moll FL, van Herwaarden JA Abstract INTRODUCTION: Endovascular aortic repair (EVAR) has improved over the last two decades. Approximately 80% of the patients presenting with an abdominal aortic aneurysm (AAA) is nowadays primarily treated with EVAR. Areas covered: In this review the differences between endovascular and open repair, the clinical characteristics needed for EVAR, the role of clinical imaging and the developments in EVAR technology will be discussed. Early mortality is lower in EVAR as compared to open repair, whereas this benefit is lost after thr...
Source: Expert Review of Medical Devices - August 2, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Removal and insertion of central venous catheters in cancer patients is associated with high symptom burden.
CONCLUSIONS: CVCs are essential for the management of cancer patients. However, they can become infected and may need to be removed. Catheter removal and insertion produced moderate to severe symptom burden in cancer patients. Safe interventions that would salvage the vascular access without worsening the infectious outcome should be explored to alleviate morbidity associated with the symptom burden of removal and re-insertion. PMID: 30067125 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - August 2, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Closed loop insulin delivery: current status of diabetes technologies and future prospects.
Authors: Majeed W, Thabit H Abstract INTRODUCTION: Type 1 diabetes is characterised by destruction of pancreatic beta cells, leading to insulin deficiency and hyperglycaemia. The mainstay of treatment remains lifelong insulin therapy as a sustainable cure has as yet proven elusive. The burden of daily management of type 1 diabetes has contributed to suboptimal outcomes for people living with the condition. Innovative technological approaches have been shown to improve glycaemic and patient-related outcomes. Areas covered: We discuss recent advances in diabetes technologies in type 1 diabetes and the 'artificial pan...
Source: Expert Review of Medical Devices - July 22, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Devices for penile traction: the long and winding road to treating Peyronie's disease.
Authors: Setia SA, Levine LA Abstract INTRODUCTION: Penile Traction Therapy (PTT) is increasingly being recognized as a viable non-surgical approach to Peyronie's Disease (PD). The goal of this article is to review the current literature on PTT with attention to traction protocols, devices, and outcomes. Areas Covered: Literature on the pathophysiology of PD, PTT as primary and adjunctive treatment for PD, perioperative use of PTT, and Vacuum Erection Devices are all reviewed. Pertinent literature was obtained from the PubMed database. The key words: "penile traction," "mechanotransduction," and...
Source: Expert Review of Medical Devices - July 19, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Optimal site selection & image fusion guidance technology to facilitate cardiac resynchronisation therapy.
Optimal site selection & image fusion guidance technology to facilitate cardiac resynchronisation therapy. Expert Rev Med Devices. 2018 Jul 18;: Authors: Sieniewicz BJ, Gould J, Porter B, Sidhu BS, Behar JM, Claridge S, Niederer S, Rinaldi CA Abstract INTRODUCTION: Cardiac resynchronisation therapy (CRT) has emerged as one of the few effective treatments for heart failure. However, up to 50% of patients derive no benefit. Suboptimal LV lead position is a potential cause of poor outcomes whilst targeted lead deployment has been associated with enhanced response rates. Image-fusion guidance systems r...
Source: Expert Review of Medical Devices - July 19, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

The Visible Heart ® project and methodologies: novel use for studying cardiac monophasic action potentials and evaluating their underlying mechanisms.
We describe the historically proposed mechanisms behind which electrode is responsible for the MAP recording, new catheters for recording these signals, and how Visible Heart methodologies can be utilized to develop and test new technologies for electrophysiologic investigations. Expert Opinion: When compared to traditional electrogram recordings, MAP waveforms provide clinical information vital to the understanding, diagnosis, and treatment of cardiac arrhythmias. New catheters and ablation technologies are routinely being assessed on reanimated large mammalian hearts (swine and human) in our laboratory. These abilities, ...
Source: Expert Review of Medical Devices - July 12, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Artificial intelligence: a new clinical support tool for stress echocardiography.
Authors: Alsharqi M, Upton R, Mumith A, Leeson P PMID: 29992841 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - July 12, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Intra-observer and Inter-observer Reliability of Visible Light Spectroscopy During Upper Gastrointestinal Endoscopy.
CONCLUSIONS: The observer reliability of VLS is fair to good with intra-observer reliability being better than inter-observer reliability. This supports the use of VLS for detection of gastrointestinal ischemia. PMID: 29973094 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - July 6, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

3D printed upper limb prosthetics.
Authors: Vujaklija I, Farina D Abstract INTRODUCTION: In the last fifteen years, the market for prosthetic arms and hands has shifted towards systems with greater degrees of actuation. There has also been a progressive use of emerging technologies to overcome hardware design challenges. Moreover, the proliferation of rapid prototyping has resulted in applications in the prosthetic market. Even though there are concerns on robustness and wide-user acceptance, the affordable and customizable solution offered by rapid prototyping, combined with the possibility for easy maintenance and repair, is very attractive for pr...
Source: Expert Review of Medical Devices - June 29, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Regulatory convergence of medical devices: a case study using ISO and IEC standards.
Authors: Imagawa K, Mizukami Y, Miyazaki S Abstract INTRODUCTION: Achieving regulatory convergence is important in providing safe and effective medical devices to patients in a timely manner. The use of standards set by the International Organization for Standardization (ISO) and the International Electrotechnical Commission (IEC), may be an important tool for regulatory convergence. The International Medical Device Regulators Forum (IMDRF) published a survey and statements regarding the use of these standards in each IMDRF jurisdiction, which showed that each jurisdiction proactively uses these standards in its re...
Source: Expert Review of Medical Devices - June 26, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Systematic review of agreement between tomosynthesis and pathologic tumor size for newly-diagnosed breast cancer and comparison with other imaging tests.
Authors: Marinovich ML, Macaskill P, Bernardi D, Houssami N Abstract Introduction Tomosynthesis is proposed to improve breast cancer assessment and staging as a complementary role to its detection capability. We examine the accuracy of tomosynthesis in measuring tumor size relative to pathology and compared with other tests. Areas covered A systematic literature search identified studies of tomosynthesis in estimating the size of newly-diagnosed breast cancers. Descriptive analyses were performed due to heterogeneity in patients, technology and methods between studies. Eight studies were eligible (678 patients). Me...
Source: Expert Review of Medical Devices - June 24, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

The STENTYS self-apposing stent technology in coronary artery disease: literature review and future directions.
Authors: Lu H, de Winter RJ, Koch KT Abstract INTRODUCTION: Coronary stent designs have been through extensive developments in the past few decades. Since the first introduction of the self-apposing STENTYS stent, several theoretical advantages of its nitinol platform have been clinically evaluated. This paper reviews the current status, ongoing work and future directions of this device. Areas covered: The OPEN (STENTYS Coronary Bifurcation Stent System fOr the PErcutaNeous treatment of de novo lesions in native bifurcated coronary arteries) trials revealed high technical success rates of the STENTYS performance in...
Source: Expert Review of Medical Devices - June 24, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

International experience with minocycline, EDTA and ethanol lock for salvaging of central line associated bloodstream infections.
CONCLUSION: Our study suggests that M-EDTA-EtOH lock therapy may be an effective intervention to salvage long-term CVCs in the setting of CLABSI/CRBSI and hemodialysis cancer patients with limited vascular access. PMID: 29927699 [PubMed - in process] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - June 24, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Cardioband system as a treatment for functional mitral regurgitation.
Authors: Ferrero Guadagnoli A, De Carlo C, Maisano F, Ho E, Saccocci M, Cuevas O, Luciani M, Kuwata S, Nietlispach F, Taramasso M Abstract INTRODUCTION: Are the current data on the Cardioband in the clinical area enough to consider it a tool for mitral regurgitation treatment? Severe secondary mitral valve insufficiency frequently affects high-risk surgical patients. The Cardioband system is a novel percutaneous surgical-like device for direct annuloplasty. It is implanted into the beating heart by transvenous femoral access, with minimal impact on hemodynamic and cardiac function during implantation. So far, it ha...
Source: Expert Review of Medical Devices - June 9, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

A Review of Haptic Simulator for Oral and Maxillofacial Surgery Based on Virtual Reality.
Authors: Chen X, Hu J Abstract INTRODUCTION: Traditional medical training in oral and maxillofacial surgery may be limited by its low efficiency and high price due to the shortage of cadaver resources. With the combination of visual rendering and feedback force, surgery simulators become increasingly popular in hospitals and medical schools as an alternative to the traditional training. Areas covered: The major goal of this review is to provide a comprehensive reference source of current and future developments of haptic oral and maxillofacial surgery simulators based on virtual reality for relevant researchers. Ex...
Source: Expert Review of Medical Devices - June 6, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Security of implantable medical devices with wireless connections: the dangers of cyber-attacks.
Authors: Pycroft L, Aziz TZ PMID: 29860880 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - June 5, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

3D printing techniques in spine surgery: the future prospects and current challenges.
Authors: Wu AM, Lin JL, Kwan KYH, Wang XY, Zhao J PMID: 29848086 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - June 2, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Use of lasers in minimally invasive spine surgery.
The objective of this review is to describe the surgical applications of laser technology in MISS and to discuss the pros and cons of laser spine surgery. Areas covered: We reviewed the medical literature to identify how lasers are being used in the current MISS techniques. We also described a variety of laser spine surgery according to the laser employed and surgical approach. There are three categories of laser surgery in MISS: (1) open microscopic laser surgery; (2) percutaneous endoscopic laser surgery; and (3) laser tissue modulation for spinal pain. Even though numerous laser procedures and related case series have d...
Source: Expert Review of Medical Devices - June 2, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Evaluation of the Macy Catheter ®: A rectal catheter for rapid medication and fluid administration.
Evaluation of the Macy Catheter®: A rectal catheter for rapid medication and fluid administration. Expert Rev Med Devices. 2018 May 30;: Authors: Macygin KMC, Kulstad E, Mokszycki RK, Goldsmith M Abstract INTRODUCTION: Health care providers are increasingly challenged to balance cost considerations for devices, drugs, and staffing all while continuing to provide excellent care. Patients in both the post-acute and acute care settings often require fluid and/or medication when their oral route is compromised and vascular access may not be warranted or immediately accessible. The rectum is an underuti...
Source: Expert Review of Medical Devices - June 1, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Agreement of white-to-white measurements with the IOLMaster 700, Atlas 9000 and Sirius systems.
CONCLUSIONS: According to our results, these three devices should not be used interchangeably for WTW diameter measurements during the clinical practice. PMID: 29806949 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - May 30, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

The Real World of blood glucose Point-of-Care Testing (POCT) System Running in China Teaching Hospital.
CONCLUSIONS: Our data indicates that the real world use of the POCT system in hospital settings in China needs more closer adherence to a quality management framework. PMID: 29737214 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - May 9, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Therapeutic options for functional mitral regurgitation in chronic heart failure.
Authors: Lowry JE, Fichtlscherer S, Witte KK Abstract INTRODUCTION: Mitral regurgitation is a common finding in patients with chronic heart failure and is associated with a progressive worsening of symptoms, reduced survival and increased cost of care. However, the use of mitral valve surgery for these patients remains controversial and has not been shown to improve survival. Consequently, research has been increasingly directed towards the nonsurgical management of this important co-morbidity of heart failure. Areas covered: The present review will describe the relevance of mitral regurgitation in people with chro...
Source: Expert Review of Medical Devices - May 7, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

The potential for machine learning algorithms to improve and reduce the cost of 3-dimensional printing for surgical planning.
Authors: Huff TJ, Ludwig PE, Zuniga JM Abstract INTRODUCTION: 3D-printed anatomical models play an important role in medical and research settings. The recent successes of 3D anatomical models in healthcare have led many institutions to adopt the technology. However, there remain several issues that must be addressed before it can become more wide-spread. Of importance are the problems of cost and time of manufacturing. Machine learning (ML) could be utilized to solve these issues by streamlining the 3D modeling process through rapid medical image segmentation and improved patient selection and image acquisition. T...
Source: Expert Review of Medical Devices - May 5, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Identifying and prioritizing concerns associated with prosthetic devices for use in a benefit-risk assessment: A mixed-methods approach.
CONCLUSION: In this pilot, we identified heterogeneity in how participants prioritize concerns for upper-limb prostheses. PMID: 29707973 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - May 2, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Haemodialysis at home: review of current dialysis machines.
Authors: Haroon S, Davenport A Abstract INTRODUCTION: Only a minority of patients with chronic kidney disease treated by hemodialysis are currently treated at home. Until relatively recently, the only type of hemodialysis machine available for these patients was a slightly smaller version of the standard machines used for in-center dialysis treatments. Areas covered: There are now an alternative generation of dialysis machines specifically designed for home hemodialysis. The home dialysis patient wants a smaller machine, which is intuitive to use, easy to trouble shoot, robust and reliable, quick to set-up and put ...
Source: Expert Review of Medical Devices - April 18, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Clinical Effectiveness and Versatility of a Sealing Hemostatic Patch (HEMOPATCH) in Multiple Surgical Specialties.
Authors: Lewis KM, Ikeme S, Olubunmi T, Kuntze CE Abstract INTRODUCTION: Intraoperative surgical sealants and hemostatic agents have been shown to reduce postoperative complications, transfusions and hospital resource utilization. Despite availability of these agents, the incidence and burden of bleeding remains high and surgeons' requirements for hemostatic control continue to evolve. A burgeoning class of hemostatic agents are hemostatic patches, which offer package-to-patient readiness and direct application. In addition, hemostatic patches may provide tissue sealing capabilities. Areas covered: This review focu...
Source: Expert Review of Medical Devices - April 18, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Patients' exposure to PVC plasticizers from ECMO circuits.
CONCLUSION: Our study shows that circuits made of PVC plasticized with TOTM against DEHP improves the safety of ECMO. PMID: 29658331 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - April 18, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

From portable dialysis to a bioengineered kidney.
FROM PORTABLE DIALYSIS TO A BIOENGINEERED KIDNEY. Expert Rev Med Devices. 2018 Apr 10;: Authors: van Gelder MK, Mihaila S, Jansen J, Wester M, Verhaar MC, Joles JA, Stamatialis D, Masereeuw R, Gerritsen K Abstract INTRODUCTION: Since the advent of peritoneal dialysis (PD) in the 1970s, the principles of dialysis have changed little. In the coming decades, several major breakthroughs are expected. Areas covered: Novel wearable and portable dialysis devices for both hemodialysis (HD) and PD are expected first. The HD devices could facilitate more frequent and longer dialysis outside of the hospital, whil...
Source: Expert Review of Medical Devices - April 12, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Overview of Impella and mechanical devices in cardiogenic shock.
Authors: Chera HH, Nagar M, Chang NL, Morales-Mangual C, Dous G, Marmur JD, Ihsan M, Madaj P, Rosen Y Abstract INTRODUCTION: Cardiogenic shock (CS) is a life-threatening condition associated with significant morbidity and mortality. The Impella (Abiomed Inc.) is an axial flow pump on a pigtail catheter that is placed across the aortic valve to unload the left ventricle by delivering non-pulsatile blood flow to the ascending aorta. It is used for high-risk percutaneous coronary intervention and CS. Areas covered: Percutaneous mechanical support devices are placed in a minimally invasive manner and provide life-savin...
Source: Expert Review of Medical Devices - March 31, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

A survival guide for endovascular declotting in dialysis access: procedures, devices, and a statistical analysis of 3,000 cases.
Authors: Kitrou PM, Katsanos K, Papadimatos P, Spiliopoulos S, Karnabatidis D Abstract INTRODUCTION: Thrombosis is the most important access-related complication. Several declotting procedures have been suggested falling mainly into two categories; thrombolysis-dependent and thrombectomy-dependent. Areas covered: Seventeen studies after 2001 have been published on percutaneous treatment of thrombosed vascular access. Authors performed a systematic review of these studies together with a parametric meta-analysis of data available investigating clinical success, postintervention assisted primary patency (PAPP) and in...
Source: Expert Review of Medical Devices - March 27, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Clinical potential of implantable wireless sensors for orthopedic treatments.
Authors: Karipott SS, Nelson BD, Guldberg RE, Ong KG Abstract INTRODUCTION: Implantable wireless sensors have been used for real-time monitoring of chemicals and physical conditions of bones, tendons and muscles to diagnose and study orthopedic diseases and injuries. Due to the importance of these sensors in orthopedic care, a critical review, which not only analyzes the underlying technologies but also their clinical implementations and challenges, will provide a landscape view on their current state and their future clinical role. Areas covered: By conducting an extensive literature search and following the leade...
Source: Expert Review of Medical Devices - March 27, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

How does the surface treatment change the cytocompatibility of implants made by Selective Laser Melting?
Authors: Matouskova L, Ackermann M, Horakova J, Capek L, Henys P, Safka J Abstract INTRODUCTION: The study investigates the potential for producing medical components via Selective Laser Melting technology (SLM). The material tested consisted of the biocompatible titanium alloy Ti6Al4V. The research involved the testing of laboratory specimens produced using SLM technology both in vitro and for surface roughness. The aim of the research was to clarify whether SLM technology affects the cytocompatibility of implants and, thus, whether SLM implants provide suitable candidates for medical use following zero or minimum...
Source: Expert Review of Medical Devices - March 27, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Drug-eluting implants for the suppression of metastatic bone disease: current insights.
Authors: Pountos I, Giannoudis PV Abstract INTRODUCTION: The fixation of impending or pathologic fractures is challenging and their successful management can have a favourable impact on the quality of life of the patient. The progression of the metastatic bone disease can cause significant pain and disability but also could result in the loosening and subsequent failure of the implants. To prevent the additional local growth, postoperative radiotherapy is often recommended, and many patients receive endocrine or chemotherapy Areas covered: Several reports support the antineoplastic drugs to bone cement as an adjuva...
Source: Expert Review of Medical Devices - March 27, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Transcatheters for Closure of Patent Foramen Ovales.
Authors: Rigatelli G, Zuin M Abstract INTRODUCTION: Nowadays patent foramen ovale (PFO) closure is considered clinically beneficial and even cost-effective over medical therapy in secondary prevention of stroke due to paradoxical embolism. Areas Covered: In this review, the authors discuss both anatomical and technical details and constructive concepts of current devices used for PFO closure. Expert Commentary: Right atrial and interatrial septum anatomy is more complex than usually thought and a unique prosthesis that fits properly to all the possible morphologies is far from being designed. Existing devices can b...
Source: Expert Review of Medical Devices - March 7, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Video laryngoscopy-assisted tracheal intubation in airway management.
Authors: Liao CC, Liu FC, Li AH, Yu HP Abstract INTRODUCTION: Video laryngoscopy-assisted tracheal intubation devices have become alternatives to traditional laryngoscopes in recent years. This review will provide information on commonly used video laryngoscopes, and their clinical applications in airway management. Areas covered: In this review, the differences between video laryngoscopy and direct laryngoscopy, and the utilization of video laryngoscopes in specific clinical settings are discussed. Expert Commentary: Video laryngoscopy should be embraced as an initial approach to intubation in patients with suspec...
Source: Expert Review of Medical Devices - March 7, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Corrigendum.
Authors: PMID: 29448844 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - February 18, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Effects of continuous and pulsatile flows generated by ventricular assist devices on renal function and pathology.
Authors: Miyamoto T, Karimov JH, Fukamachi K Abstract INTRODUCTION: Continuous-flow (CF) left ventricular assist devices (LVADs) are widely used to treat end-stage heart failure. Despite substantial improvement in clinical results, numerous complications remain associated with this technology. Worsening renal function is one, associated with morbidity and mortality in patients supported by CF LVADs. The effects of CF LVAD support on renal function have been investigated since the mid-1990s by many research groups. Area covered: We review the current status of LVAD therapy, experimental results regarding the effects...
Source: Expert Review of Medical Devices - February 7, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Review of long-term outcomes of disc arthroplasty for symptomatic single level cervical degenerative disc disease.
This report reviews results of the Prestige, proDisc-C, Mobi-C Disc and various other arthroplasty devices and provides an overall report of the longest term available data and comparisons between devices. Areas Covered: This review summarizes previously published articles in a literature search using keywords: 'cervical disc arthroplasty', 'cervical total disc replacement', 'anterior cervical decompression and fusion', 'anterior cervical arthrodesis', 'symptomatic degenerative disc disease' and commercial names of devices. Expert Commentary: CDA, with the devices reviewed, resulted in favorable outcomes in comparison to A...
Source: Expert Review of Medical Devices - February 1, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Antibiotic-loaded cement spacers - lessons learned from the past 20 years.
Authors: Anagnostakos K, Fink B Abstract INTRODUCTION: The use of antibiotic-impregnated cement spacers is an established method in the treatment of periprosthetic hip and knee joint infections. Over the past 20 years, the indications for spacer implantation have expanded, and various modified surgical techniques have been proposed to manage difficult anatomical situations. To ensure clinical success, knowledge about the cement impregnation and the pharmacokinetic properties of antibiotic-loaded bone cement is an indispensable premise. Areas covered: In this review, techniques for the fabrication of cement spacers,...
Source: Expert Review of Medical Devices - February 1, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

The tear turnover and tear clearance tests - a review.
Authors: Garaszczuk IK, Montes Mico R, Iskander DR, Expósito AC Abstract INTRODUCTION: The aim is to provide a summary of methods available for the assessment of tear turnover and tear clearance rates. The review defines tear clearance and tear turnover and describes their implication for ocular surface health. Additionally, it describes main types of techniques for measuring tear turnover, including fluorescein tear clearance tests, techniques utilizing electromagnetic spectrum and tracer molecule and novel experimental techniques utilizing optical coherence tomography and fluorescein profilometry. Areas co...
Source: Expert Review of Medical Devices - February 1, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Imaging devices - today's innovations and tomorrow's potential.
Authors: Meurs BV PMID: 29374980 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - January 31, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Devices for ex vivo heart and lung perfusion.
Authors: Schraufnagel DP, Steffen RJ, Vargo PR, Attia T, Elgharably H, Hasan SM, Bribriesco A, Wierup P Abstract INTRODUCTION: The number of organs available for heart and lung transplantation is far short of the number that is needed to meet demand. Perfusion and ventilation of donor organs after procurement has led to exciting advances in the field of cardiothoracic transplantation. The clinical implications of this technology allows for techniques to evaluate the quality of an organ, active rehabilitation of organs after procurement and prior to implantation, and increased time between organ procurement and impl...
Source: Expert Review of Medical Devices - January 31, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Accuracy and repeatability of the Dopplex Ability.
CONCLUSION: We found the Dopplex device to demonstrate suboptimal accuracy and repeatability in assessing ABI/PVR, and it was deemed unsuitable for use in our community. PMID: 29353518 [PubMed - as supplied by publisher] (Source: Expert Review of Medical Devices)
Source: Expert Review of Medical Devices - January 23, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

The era of biofunctional biomaterials in orthopedics: what does the future hold?
Authors: Rehman M, Madni A, Webster TJ Abstract INTRODUCTION: Titanium-based materials do not fulfill all the requirements of orthopedic implants due to a mismatch in mechanical properties with bone which are prone to change during the course of bone growth. Biofunctional biomaterials are a new class of materials that show bioactivity and adaptability at any stage of bone growth. Areas covered: Different biofunctional biomaterials have evolved over time that can enhance calcium phosphate (CaP) precipitation, stimulate osteogenic differentiation, and can control osteoblast gene expression. These materials include me...
Source: Expert Review of Medical Devices - January 21, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

A comprehensive review of endoscopic ultrasound core biopsy needles.
Authors: James TW, Baron TH Abstract INTRODUCTION: Endoscopic ultrasound (EUS)-guided tissue acquisition by-fine needle biopsy (EUS-FNB) developed over the last two decades as an attempt to overcome the limitations of fine needle aspiration (FNA). There are now three commercially available second-generation FNB needles with different tip designs. Areas covered: In this review the roles of EUS-FNA and FNB, the history and evolution of the EUS core biopsy needle are addressed followed by a presentation of currently available needles. Literature search was conducted using MEDLINE, Controlled Trials Register, US Patent...
Source: Expert Review of Medical Devices - January 18, 2018 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research