Assessment of the toxicity of different antiretroviral drugs and their combinations on Sertoli and Leydig cells
. (Source: Drug and Chemical Toxicology)
Source: Drug and Chemical Toxicology - April 22, 2024 Category: Toxicology Authors: Merve BaysalAbdullah Burak KaradumanB üşra Korkut ÇelikateşÖzlem Atlı-EklioğluSinem IlgınDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey Source Type: research

People’s beliefs about pronouns reflect both the language they speak and their ideologies.
Journal of Experimental Psychology: General, Vol 153(5), May 2024, 1388-1406; doi:10.1037/xge0001565Pronouns often convey information about a person’s social identity (e.g., gender). Consequently, pronouns have become a focal point in academic and public debates about whether pronouns should be changed to be more inclusive, such as for people whose identities do not fit current pronoun conventions (e.g., gender nonbinary individuals). Here, we make an empirical contribution to these debates by investigating which social identities lay speakers think that pronouns should encode (if any) and why. Across four studies, parti...
Source: Journal of Experimental Psychology: General - April 22, 2024 Category: Psychiatry & Psychology Source Type: research

Primary immune regulatory disorders (PIRD): expanding the mutation spectrum in Turkey and identification of sixteen novel variants
In this study, we report the identification of 38 disease-causing variants, including 16 novel ones, detected in 40 patients across 15 distinct PIRD genes. The application of next-gene ration sequencing enabled rapid and precise diagnosis of patients with PIRDs. (Source: Immunologic Research)
Source: Immunologic Research - April 22, 2024 Category: Allergy & Immunology Source Type: research

The Effects of Corticosteroid and Nonsteroid Anti-Inflammatory Therapies on Permanent Hypothyroidism Occurring After the Subacute Thyroiditis
. (Source: Endocrine Research)
Source: Endocrine Research - April 21, 2024 Category: Endocrinology Authors: Naile GokkayaKadriye Aydin TezcanDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kartal Dr. Lutfi Kirdar City Hospital, Kartal, Turkey Source Type: research

The association of FRAX with predictors of falls in the assessment of postmenopausal osteoporosis in Turkey: the fracture study of Turkey (FRACT study)
ConclusionAssessment of fall risk predictors should be one of the major pillars in the physical evaluation of osteoporotic patients in the FLS setting. FRAX is a useful tool to determine the fracture risk of patients with both static and dynamic balance impairments. Combining balance assessment with FRAX may be an important step to optimize osteoporosis risk assessment. (Source: Archives of Osteoporosis)
Source: Archives of Osteoporosis - April 20, 2024 Category: Orthopaedics Source Type: research

The Environment and Headache: a Narrative Review
AbstractPurpose of ReviewIn this narrative review, we summarize the peer-reviewed literature published between 2017 and 2022 that evaluated ambient environmental risk factors for primary headache disorders, which affect more than half of the population globally. Primary headache disorders include migraine, tension-type headache (TTH), and trigeminal and autonomic cephalalgias (TAC).Recent findingsWe identified 17 articles that met the inclusion criteria via PubMed or Google Scholar. Seven studies (41%) relied on data from US populations. The remaining studies were conducted in China, Taiwan, Germany, Ghana, Japan, the Neth...
Source: Current Environmental Health Reports - April 20, 2024 Category: Environmental Health Source Type: research

The association of FRAX with predictors of falls in the assessment of postmenopausal osteoporosis in Turkey: the fracture study of Turkey (FRACT study)
ConclusionAssessment of fall risk predictors should be one of the major pillars in the physical evaluation of osteoporotic patients in the FLS setting. FRAX is a useful tool to determine the fracture risk of patients with both static and dynamic balance impairments. Combining balance assessment with FRAX may be an important step to optimize osteoporosis risk assessment. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 20, 2024 Category: Orthopaedics Source Type: research

Mindfulness and Well-being: A Longitudinal Serial Mediation Model of Psychological Adjustment and COVID-19 Fear
AbstractNumerous studies have been carried out globally related to COVID-19 since the onset of the pandemic, most of which were cross-sectional. Therefore, there is a need for longitudinal studies to fully understand the impact of COVID-19 on mental health. In the present longitudinal study, our aim was to examine whether psychological adjustment and fear of COVID-19 would serially mediate the relationship between mindfulness and well-being in a Turkish sample (N = 300,Mage=22.21 years, SD  = 3.01, 60.3% female). The results of a two-wave longitudinal study were analyzed via bootstrapping. The findings of the seria...
Source: Journal of Rational-Emotive and Cognitive-Behavior Therapy - April 19, 2024 Category: Psychiatry & Psychology Source Type: research

Dissecting genetic architecture of rare dystonia: genetic, molecular and clinical insights
Conclusions Here, using a structured approach, we have characterised a clinically and genetically well-defined dystonia cohort from Turkey, where dystonia has not been widely studied, and provided an uncovered genetic basis, which will facilitate diagnostic dystonia research. (Source: Journal of Medical Genetics)
Source: Journal of Medical Genetics - April 19, 2024 Category: Genetics & Stem Cells Authors: Atasu, B., Simon-Sanchez, J., Hanagasi, H., Bilgic, B., Hauser, A.-K., Guven, G., Heutink, P., Gasser, T., Lohmann, E. Tags: Open access Neurogenetics Source Type: research

Immunosuppressive treatment results in patients with primary IgA nephropathy in Turkiye; the data from TSN-GOLD working group
CONCLUSION: CS can significantly improve remission in high-risk Turkish IgAN patients, despite the reliance on non-quantitative endpoints for favorable renal outcomes. Key predictors of remission include baseline proteinuria and specific histological markers. It is crucial to carefully weigh the risks and benefits of immunosuppressive therapy for these patients.PMID:38637275 | DOI:10.1080/0886022X.2024.2341787 (Source: Renal Failure)
Source: Renal Failure - April 18, 2024 Category: Urology & Nephrology Authors: Aysegul Oruc Abdullah Sumnu Ayd ın Turkmen Taner Basturk Egemen Cebeci Kenan Turgutalp Hakk ı Cetinkaya M üge Uzerk Kibar Nurhan Seyahi Erhan Tatar Metin Ergul Ülver Derici Mehmet Deniz Ayl ı Musa P ınar Bet ül Bakar R ümeyza Kazancıoglu Abd ülm Source Type: research

Evaluation using the SWAT model of the effects of land use land cover changes on hydrological processes in the Gala Lake Basin, Turkey
AbstractChanges in hydrological processes in watersheds are triggered by various factors, including land use land cover changes (LULCC) emerging from human activities. Hence, it is crucial to elucidate the interaction among hydrological processes to improve sustainable water management plans. The current study explored the effects of LULCC on hydrological processes in the Gala Lake catchment over a 30-year temporal period. In this context, to evaluate LULCC, land cover maps were obtained using the supervised classification method with Landsat images (5 TM, 7 ETM+, 8 OLI) of 1993, 2008, and 2023. Hydrological processes were...
Source: Environmental Quality Management - April 18, 2024 Category: Environmental Health Authors: Emine Kele ş Özgenç Tags: RESEARCH ARTICLE Source Type: research

Effects of dependent care theory-based post-surgical home care intervention on self-care, symptoms, and caregiver burden in patients with primary brain tumor and their caregivers: a randomized controlled trial
ConclusionDependent care theory-based post-surgical home care intervention increased patients ’ self-care and reduced symptoms and their effects. It also reduced the caregiver burden. Dependent care theory can guide the nursing practices of nurses who provide institutional and/or home care services to patients with chronic diseases and their caregivers.Trial RegistrationNCT05328739 on April 14, 2022 (retrospectively registered). (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 18, 2024 Category: Cancer & Oncology Source Type: research

The effect of video-based education program applied before children's pediatric Magnetic Resonance Imaging (MRI) on anxiety in Turkey: A randomized controlled study
This study is a randomized controlled trial conducted to examine the effects of a Turkish video-based education program on scanned image quality and child and parent anxiety during Magnetic Resonance Imaging (MRI). (Source: Journal of Pediatric Nursing)
Source: Journal of Pediatric Nursing - April 18, 2024 Category: Nursing Authors: Sumeyye Ozdemir, Tulay Kuzlu Ayyildiz Source Type: research

Labiaplasty Outcomes and Complications in Turkish Women: A Multicentric Study
ConclusionConsidering the heterogeneity and low quality of the existing studies on this subject, this study provides valuable information for surgeons practicing in this field. However, further research is clearly warranted as female genital aesthetic procedures are being performed with a steadily increasing trend. (Source: International Urogynecology Journal and Pelvic Floor Dysfunction)
Source: International Urogynecology Journal and Pelvic Floor Dysfunction - April 18, 2024 Category: OBGYN Source Type: research

Genetic variants of ANRIL and coronary artery disease: Insights from a Turkish study population
CONCLUSIONS: In conclusion, selected ANRIL polymorphisms were associated with CAD presence/severity and CAD risk factors, T2DM, and hypertension. Notably, this study, the largest sample-sized study examining the effects of selected polymorphisms on CAD and its risk factors among Turkish individuals, supported the findings of previous studies conducted on different ethnicities.PMID:38631653 | DOI:10.1016/j.gene.2024.148475 (Source: Gene)
Source: Gene - April 17, 2024 Category: Genetics & Stem Cells Authors: Aybike Sena Ozuynuk-Ertugrul Cemre Buse Kirsan Aycan Fahri Erkan Berkay Ekici Evrim Komurcu-Bayrak Neslihan Coban Source Type: research