Successful management of postoperative tracheal metastasis in small cell lung cancer with radiotherapy and durvalumab: A case report
Thorac Cancer. 2023 Nov 3. doi: 10.1111/1759-7714.15143. Online ahead of print.ABSTRACTThe patient in this report was a 73-year-old male who was diagnosed with small cell lung cancer (T3N0M0 stage IIB) after presenting with a 5.5 cm tumor detected in the right lower lobe of the lung by radiography. After right lower lobectomy and lymphadenectomy, postoperative adjuvant chemotherapy was administered with cisplatin and etoposide. At 27 months after surgery, the patient complained of wheezing. Tracheal metastasis was identified through computed tomography and bronchoscopy. Biopsy confirmed metastasis of small cell lung cancer...
Source: Cancer Control - November 3, 2023 Category: Cancer & Oncology Authors: Yasoo Sugiura Hiroyuki Fujimoto Toshinori Hashizume Source Type: research

Successful management of postoperative tracheal metastasis in small cell lung cancer with radiotherapy and durvalumab: A case report
Thorac Cancer. 2023 Nov 3. doi: 10.1111/1759-7714.15143. Online ahead of print.ABSTRACTThe patient in this report was a 73-year-old male who was diagnosed with small cell lung cancer (T3N0M0 stage IIB) after presenting with a 5.5 cm tumor detected in the right lower lobe of the lung by radiography. After right lower lobectomy and lymphadenectomy, postoperative adjuvant chemotherapy was administered with cisplatin and etoposide. At 27 months after surgery, the patient complained of wheezing. Tracheal metastasis was identified through computed tomography and bronchoscopy. Biopsy confirmed metastasis of small cell lung cancer...
Source: Cancer Control - November 3, 2023 Category: Cancer & Oncology Authors: Yasoo Sugiura Hiroyuki Fujimoto Toshinori Hashizume Source Type: research

Successful management of postoperative tracheal metastasis in small cell lung cancer with radiotherapy and durvalumab: A case report
At 27  months after right lower lobectomy and lymphadenoctomy, tracheal metastasis was identified. Four months after irradiation and administration of duralumab, the nodule had vanished and normal mucosa could be observed. At 49 months after surgery, a nodule in the subglottic space was discovered. As of 61 months after surgery, the patient is reccurence free since the second course of radiotherapy. AbstractThe patient in this report was a 73-year-old male who was diagnosed with small cell lung cancer (T3N0M0 stage IIB) after presenting with a 5.5  cm tumor detected in the right lower lobe of the lung by radiograph...
Source: Thoracic Cancer - November 3, 2023 Category: Cancer & Oncology Authors: Yasoo Sugiura, Hiroyuki Fujimoto, Toshinori Hashizume Tags: CASE REPORT Source Type: research

Tracheoesophageal fistula development following radiotherapy and tyrosine kinase inhibitors in a patient with advanced follicular thyroid carcinoma: a case-based review
ConclusionThis case report highlights a rare cause of TEF development in a patient having TKI therapy post-RT for advanced FTC. It highlights the importance of monitoring TEF development in this cohort of patients. It demonstrates the importance of patient counselling and education regarding treatment options and the rare side effects of treatments. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 3, 2023 Category: General Medicine Source Type: research

Lower respiratory tract involvement in recurrent respiratory papillomatosis in a multicentric cohort study
This study describes the characteristics of Jo and AoRRP LRT at adulthood.French and Quebecers’ national retrospective study of the clinical, histological, therapeutic and prognostic characteristics with RRP-LRT.Among the 67 patients (pts), 17 (25%) were JoRRP and 50 (75%) AoRRP. The mean age at diagnosis was 5 yrs for JoRRP and 54 yrs for AoRRP. ENT involvement was observed in all JoRRP and in 23 (46%) AoRRP. Lung involvement was observed in 11 (76%) JoRRP and 2 (4%) AoRRP. Mean latency duration between ENT and lung involvement was 26 yrs in JoRRP and 4 yrs in AoRRP. Lung CT-scan findings were cysts in 11 pts (74%) ...
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Maitre, T., Ratsihorimanana, R., Dusselier, M., Mangiapan, G., Ngo, M. T., Guibert, N., Fournier, C., Matar, M., Jouneau, S., Bourdin, A., Egenod, T., Wermert, D., Favrolt, N., Freynet, O., Gounand, V., Borie, R., Caliandro, R., Boitiaux, J. F., Mankikian Tags: Rare ILD/DPLD Source Type: research

Prognostic factors after airway stenting for malignant tracheo- or broncho-oesophageal fistulas.
Conclusion: Bronchoscopic treatment of TOF is associated with a poor survival that is related with tobacco use, PS and the absence of an oesophageal stent, but not with histology, previous treatments or the size of the fistula. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Edme, J., Fournier, C., Zea Obando, C., Cellerin, L., Wallyn, F., Lachkar, S., Egenod, T., Gut Gobert, C., Perrot, L., Lorut, C., Vergnon, J. M., Bourinet, V., Legodec, J., Lepage, B., Dutau, H., Guibert, N. Tags: Interventional pulmonology Source Type: research

Feasibility using bronchoscopic specimens for next-generation sequencing in resectable non-small lung cancer
In conclusion, NGS using bronchoscopic specimens in resectable NSCLC was generally as feasible as in unresectable cases. Provided it should be approached for ELs and PLs if possible. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Yano, K., Matsumoto, Y., Furuse, H., Uchimura, K., Imabayashi, T., Tsuchida, T. Tags: Lung cancer Source Type: research

Tracheostomy Tube Exchange Failure Under General Anesthesia: A Case Report and Retrospective Analysis
Anesth Prog. 2023 Sep 1;70(3):120-123. doi: 10.2344/anpr-70-02-05.ABSTRACTA 54-year-old man with squamous cell carcinoma of the tongue underwent bilateral cervical lymph node dissection, total tongue resection, forearm flap reconstruction, and tracheostomy. The plan was to replace the oral endotracheal tube (ETT) with a cuffed tracheostomy tube at the end of the surgical case while the patient was still under general anesthesia. No major complications were expected as the tracheal foramen was visible once surgical access was obtained. However, removal of the ETT and subsequent placement of the tracheostomy tube failed twic...
Source: Anesthesia Progress - October 18, 2023 Category: Anesthesiology Authors: Yuki Kojima Ryozo Sendo Kazuya Hirabayashi Source Type: research