Influence of Thyroglobulin (Tg) Autoantibodies on Tg levels Measured by Different Methodologies: (IMA, LC-MS/MS and RIA)
CONCLUSIONS: 1) Between-method Tg variability necessitates method continuity when monitoring the Tg trends of TgAb- DTC patients. 2) The presence and concentration of TgAb appeared to have a lowering effect on serum Tg measured by all methodologies (IMA, MS and RIA). 3) Since the reliability of Tg measured in the presence of TgAb is often uncertain, the TgAb trend (measured by the same method) may be a useful surrogate DTC tumor marker.PMID:38686504 | DOI:10.1210/clinem/dgae286 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 30, 2024 Category: Endocrinology Authors: Ivana Petrovic Jonathan LoPresti Shireen Fatemi Andrew Gianoukakis Kenneth Burman Cristiane J Gomez-Lima Caroline T Nguyen Carole Ann Spencer Source Type: research
The Underestimated Impact of Hashimoto Thyroiditis on Thyroid Papillary Carcinoma
In this study, our aim is to investigate the effect of the presence of HT on clinicopathological data in patients with PTC. All 356 patients whose pathology was reported as PTC who were operated between 2015 and 2023 were included in the study. PTC patients were divided into 2 groups as those with and without HT. The effect of HT association on clinicopathological features was investigated. In 356 PTC patients, the rate of HT was 31.2%. PTC patients with HT had less multifocality (p < 0.05), more lymph node metastases (LNM) (p < 0.01) compared to PTC patients without HT. The presence of HT did not affect th...
Source: Updates in Surgery - April 30, 2024 Category: Surgery Source Type: research
Metastatic Papillary Thyroid Microcarcinoma Presenting as a Branchial Cleft Cyst in Young Female
We report a rare case of lateral cystic neck mass in a 24-year-old female patient diagnosed as metastatic PTC. The patient was diagnosed after she underwent surgical excision of branchial cleft cyst. Later prospectively the patient underwent total thyroidectomy which revealed papillary thyroid micro invasive carcinoma. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 30, 2024 Category: ENT & OMF Source Type: research
Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 29, 2024 Category: Cancer & Oncology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research
Emergency Department Use in Adolescent and Young Adult Cancer Early Survivors from 2006 to 2020
Conclusion: ED utilization declined as time from diagnosis elapsed, but higher utilization was associated with social determinants of health and cancer types.PMID:38682323 | DOI:10.1089/jayao.2023.0174 (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Karen J Wernli Eric C Haupt Neetu Chawla Thearis Osuji Ernest Shen Andrew B Smitherman Mallory Casperson Anne C Kirchhoff Bradley J Zebrack Theresa H M Keegan Lawrence Kushi Christopher Baggett Heydon K Kaddas Kathryn J Ruddy Candice A M Sauder Theodore W Source Type: research
Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research
Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 29, 2024 Category: Cancer & Oncology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research
Emergency Department Use in Adolescent and Young Adult Cancer Early Survivors from 2006 to 2020
Conclusion: ED utilization declined as time from diagnosis elapsed, but higher utilization was associated with social determinants of health and cancer types.PMID:38682323 | DOI:10.1089/jayao.2023.0174 (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Karen J Wernli Eric C Haupt Neetu Chawla Thearis Osuji Ernest Shen Andrew B Smitherman Mallory Casperson Anne C Kirchhoff Bradley J Zebrack Theresa H M Keegan Lawrence Kushi Christopher Baggett Heydon K Kaddas Kathryn J Ruddy Candice A M Sauder Theodore W Source Type: research
Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research
Emergency Department Use in Adolescent and Young Adult Cancer Early Survivors from 2006 to 2020
Conclusion: ED utilization declined as time from diagnosis elapsed, but higher utilization was associated with social determinants of health and cancer types.PMID:38682323 | DOI:10.1089/jayao.2023.0174 (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Karen J Wernli Eric C Haupt Neetu Chawla Thearis Osuji Ernest Shen Andrew B Smitherman Mallory Casperson Anne C Kirchhoff Bradley J Zebrack Theresa H M Keegan Lawrence Kushi Christopher Baggett Heydon K Kaddas Kathryn J Ruddy Candice A M Sauder Theodore W Source Type: research
Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research
Nuclear features in thyroid cytology: features helpful for a morphological diagnosis in routine practice
This review article describes nuclear features of a range of thyroid lesions to enable confident diagnosis in a multidisciplinary thyroid cancer setting. It is hoped that this will serve as a handy aide-m émoire when faced with diagnosis of thyroid FNA (fine needle aspiration) cytology in day-to-day practice. The existing literature has been reviewed to give the reader an overview of the classification systems in thyroid cytology and various entities described therein. The lesions are broadly catego rised as benign, malignant, and indeterminate. (Source: Diagnostic Histopathology)
Source: Diagnostic Histopathology - April 29, 2024 Category: Pathology Authors: Priya Bhagwat, Sabine Pomplun Tags: Mini-symposium: endocrine pathology Source Type: research
Biological functions of LncRNA SNHG14 in the development of thyroid cancer cells via targeting miR-206
This study aimed to determine lncRNA SNHG14 and miR-206 in Thyroid Cancer ( TC) and to explore the related mechanisms. Sixty-four samples of thyroid tissue were collected from patients with TC. TC cell lines and a normal human thyroid cell line (HTori-3) were bought. lncRNA SNHG14-siRNA (si-lncRNA SNHG14), lncRNA SNHG14-shRNA (sh-lncRNA SNHG14), blank plasmid (siRNA-NC), miR-206-inhibitor, miR-206-mimics were transfected into BHT101 and Ocut-2C cells. qRT-PCR quantified the expression of lncRNA SNHG14 and miR-206, and the expression of vimentin, Snail, N-cadherin, Slug, E-cadherin and ZO-1 proteins were identified via WB. ...
Source: Mol Biol Cell - April 28, 2024 Category: Molecular Biology Authors: Yiming Sang Rui Min Tao Huang Jizong Zhang Source Type: research
Naive and regulatory B-cell transcription patterns guide the increased risk of papillary thyroid carcinoma in obesity
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):118-126. doi: 10.14715/cmb/2024.70.4.19.ABSTRACTA growing number of studies suggest a positive association between obesity and the high incidence of papillary thyroid cancer (PTC), suggesting that the abnormal levels of adipokines associated with obesity may be a risk factor for these aggressive thyroid cancers, but the underlying regulatory mechanisms are not yet clear. We downloaded bulk RNA sequence data for subcutaneous adipose tissue (SAT) in obesity and healthy population and tumor tissues of PTC from GEO database. Through analysis of Differential Expression Genes (DE...
Source: Mol Biol Cell - April 28, 2024 Category: Molecular Biology Authors: Zihui Yu Ziying Xu Shang Li Ziyan Tian Jing Yuan Source Type: research
