Antimicrobial resistance landscape in a metropolitan city context using open drain wastewater-based metagenomic analysis
Environ Res. 2024 Mar 17:118556. doi: 10.1016/j.envres.2024.118556. Online ahead of print.ABSTRACTOne Health concept recognizes the inextricable interactions of diverse ecosystems and their subsequent effect on human, animal and plant health. Antimicrobial resistance (AMR) is a major One Health concern and is predicted to cause catastrophes if appropriate measures are not implemented. To understand the AMR landscape in a south Indian metropolitan city, metagenomic analysis of open drains was performed. The data suggests that in January 2022, macrolide class of antibiotics contributed the highest resistance of 40.1% in the ...
Source: Environmental Research - March 19, 2024 Category: Environmental Health Authors: Manas Kumar Madhukar Nirupama Singh V Rajesh Iyer Divya Tej Sowpati Karthik Bharadwaj Tallapaka Rakesh Kumar Mishra Shivranjani Chandrashekhar Moharir Source Type: research

Comparative genomics of an extensively drug resistant strain Klebsiella pneumoniae IITR008 with international high-risk clonal lineage ST147 isolated from river water
Antonie Van Leeuwenhoek. 2024 Mar 15;117(1):57. doi: 10.1007/s10482-024-01955-z.ABSTRACTCarbapenem resistant Klebsiella pneumoniae causing severe infection resulting in morbidity and mortality have become a global health concern. K. pneumoniae with sequence type ST147 is an international high-risk clonal lineage, genomic studies have been done on K. pneumoniae ST147 isolated from clinical origin but genomic data for environmental K. pneumoniae ST147 is very scarce. Herein, K. pneumoniae IITR008, an extensively drug resistant and potentially hypervirulent bacterium, was isolated from Triveni Sangam, the confluence of three ...
Source: Antonie van Leeuwenhoek - March 16, 2024 Category: Microbiology Authors: Deeksha Singh Shilpee Pal Srikrishna Subramanian Natesan Manickam Source Type: research

Phyto-fabricated ZnO nanoparticles for anticancer, photo-antimicrobial effect on carbapenem-resistant/sensitive Pseudomonas aeruginosa and removal of tetracycline
Bioprocess Biosyst Eng. 2024 Mar 16. doi: 10.1007/s00449-024-02984-8. Online ahead of print.ABSTRACTAlternanthera sessilis (AS) leaf extract was used to synthesize zinc oxide nanoparticles (ZnO NPs). Bioanalytical characterization techniques such as X-ray diffraction (XRD) and field emission scanning electron microscope (FESEM) confirmed the formation of crystalline ZnO NPs with average sizes of 40 nm. The AS-ZnO NPs antimicrobial activity was analyzed under dark (D) and white light (WL) conditions. The improved antimicrobial activity was observed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis at the...
Source: Bioprocess and Biosystems Engineering - March 16, 2024 Category: Biomedical Engineering Authors: Gopinath Venkatraman Priyadarshini Sakthi Mohan Maryam Mohammed Mashghan Kar-Cheng Wong Puteri Shafinaz Abdul-Rahman Kumutha Malar Vellasamy Abdurahman Hajinur Hirad Abdullah A Alarfaj Shifa Wang Source Type: research

Comparative genomics of an extensively drug resistant strain Klebsiella pneumoniae IITR008 with international high-risk clonal lineage ST147 isolated from river water
Antonie Van Leeuwenhoek. 2024 Mar 15;117(1):57. doi: 10.1007/s10482-024-01955-z.ABSTRACTCarbapenem resistant Klebsiella pneumoniae causing severe infection resulting in morbidity and mortality have become a global health concern. K. pneumoniae with sequence type ST147 is an international high-risk clonal lineage, genomic studies have been done on K. pneumoniae ST147 isolated from clinical origin but genomic data for environmental K. pneumoniae ST147 is very scarce. Herein, K. pneumoniae IITR008, an extensively drug resistant and potentially hypervirulent bacterium, was isolated from Triveni Sangam, the confluence of three ...
Source: Antonie van Leeuwenhoek - March 16, 2024 Category: Microbiology Authors: Deeksha Singh Shilpee Pal Srikrishna Subramanian Natesan Manickam Source Type: research

Phyto-fabricated ZnO nanoparticles for anticancer, photo-antimicrobial effect on carbapenem-resistant/sensitive Pseudomonas aeruginosa and removal of tetracycline
Bioprocess Biosyst Eng. 2024 Mar 16. doi: 10.1007/s00449-024-02984-8. Online ahead of print.ABSTRACTAlternanthera sessilis (AS) leaf extract was used to synthesize zinc oxide nanoparticles (ZnO NPs). Bioanalytical characterization techniques such as X-ray diffraction (XRD) and field emission scanning electron microscope (FESEM) confirmed the formation of crystalline ZnO NPs with average sizes of 40 nm. The AS-ZnO NPs antimicrobial activity was analyzed under dark (D) and white light (WL) conditions. The improved antimicrobial activity was observed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis at the...
Source: Bioprocess and Biosystems Engineering - March 16, 2024 Category: Biomedical Engineering Authors: Gopinath Venkatraman Priyadarshini Sakthi Mohan Maryam Mohammed Mashghan Kar-Cheng Wong Puteri Shafinaz Abdul-Rahman Kumutha Malar Vellasamy Abdurahman Hajinur Hirad Abdullah A Alarfaj Shifa Wang Source Type: research

Comparative genomics of an extensively drug resistant strain Klebsiella pneumoniae IITR008 with international high-risk clonal lineage ST147 isolated from river water
Antonie Van Leeuwenhoek. 2024 Mar 15;117(1):57. doi: 10.1007/s10482-024-01955-z.ABSTRACTCarbapenem resistant Klebsiella pneumoniae causing severe infection resulting in morbidity and mortality have become a global health concern. K. pneumoniae with sequence type ST147 is an international high-risk clonal lineage, genomic studies have been done on K. pneumoniae ST147 isolated from clinical origin but genomic data for environmental K. pneumoniae ST147 is very scarce. Herein, K. pneumoniae IITR008, an extensively drug resistant and potentially hypervirulent bacterium, was isolated from Triveni Sangam, the confluence of three ...
Source: Antonie van Leeuwenhoek - March 16, 2024 Category: Microbiology Authors: Deeksha Singh Shilpee Pal Srikrishna Subramanian Natesan Manickam Source Type: research

Phyto-fabricated ZnO nanoparticles for anticancer, photo-antimicrobial effect on carbapenem-resistant/sensitive Pseudomonas aeruginosa and removal of tetracycline
Bioprocess Biosyst Eng. 2024 Mar 16. doi: 10.1007/s00449-024-02984-8. Online ahead of print.ABSTRACTAlternanthera sessilis (AS) leaf extract was used to synthesize zinc oxide nanoparticles (ZnO NPs). Bioanalytical characterization techniques such as X-ray diffraction (XRD) and field emission scanning electron microscope (FESEM) confirmed the formation of crystalline ZnO NPs with average sizes of 40 nm. The AS-ZnO NPs antimicrobial activity was analyzed under dark (D) and white light (WL) conditions. The improved antimicrobial activity was observed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis at the...
Source: Bioprocess and Biosystems Engineering - March 16, 2024 Category: Biomedical Engineering Authors: Gopinath Venkatraman Priyadarshini Sakthi Mohan Maryam Mohammed Mashghan Kar-Cheng Wong Puteri Shafinaz Abdul-Rahman Kumutha Malar Vellasamy Abdurahman Hajinur Hirad Abdullah A Alarfaj Shifa Wang Source Type: research