Supraphysiologic Testosterone Administration Impairs Late Osseointegration in Male Rats
CONCLUSIONS: Testosterone cypionate in supraphysiologic dose impaired late-phase osseointegration in rat tibiae.PMID:38416000 | DOI:10.11607/jomi.10263 (Source: International Journal of Oral and Maxillofacial Implants)
Source: International Journal of Oral and Maxillofacial Implants - February 28, 2024 Category: ENT & OMF Authors: Vin ícius de Paiva Gonçalves Felipe Eduardo Pinotti Lu ís Carlos Spolidorio Elcio Marcantonio Junior Guilherme Jos é Pimentel Lopes de Oliveira Joao Paulo Steffens Source Type: research

Enhancing pre-transplant cardiac assessment: Validation and utility of the cad-LT score with CCTA in liver transplant candidates
CONCLUSIONS: The use of CCTA in patients deemed intermediate- to high-risk by the CAD-LT score has the potential to reduce the need for invasive coronary angiography in patients undergoing LT workup.PMID:38395260 | DOI:10.1016/j.ijcard.2024.131895 (Source: Atherosclerosis)
Source: Atherosclerosis - February 23, 2024 Category: Cardiology Authors: Thalys Sampaio Rodrigues Ahthavan Narendren Benjamin Cailes Ruth P Lim Laurence Weinberg Adam Testro Avik Majumdar Marie Sinclair Omar Farouque Anoop N Koshy Source Type: research

Enhancing pre-transplant cardiac assessment: Validation and utility of the cad-LT score with CCTA in liver transplant candidates
Coronary computed tomography angiography (CCTA) is increasingly being used in the preoperative workup for liver transplantation (LT). We sought to assess the utility of integrating CCTA with the novel CAD-LT (Coronary Artery Disease in Liver Transplantation) score and its impact on reducing the need for invasive coronary angiography prior to LT. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - February 21, 2024 Category: Cardiology Authors: Thalys Sampaio Rodrigues, Ahthavan Narendren, Benjamin Cailes, Ruth P. Lim, Laurence Weinberg, Adam Testro, Avik Majumdar, Marie Sinclair, Omar Farouque, Anoop N. Koshy Source Type: research

19. Telehealth Versus In-Person Instruction for Adolescents and Young Adults Initiating Gender-Affirming Testosterone Therapy
During the COVID-19 pandemic, the US healthcare system made significant shifts towards providing telehealth services. For the approximately 700,000 adolescents and young adults (AYA) aged 13-25 in the U.S. who identify as transgender and often face considerable barriers to receiving healthcare, opportunities arose to offer gender-affirming care via telehealth. One aspect of care that was often delivered in-person was testosterone injection teaching, and our center trained nurses to deliver injection teaching via a single video visit. (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - January 30, 2024 Category: Child Development Authors: Kira J. Nightingale, Scott K. Jelinek, Caleb Jones, Linda M. Bevington, Kaja Darien, Alexander Ding, Andi Fu, Linda S. Kocent, Miriam Langer, Kevin Su, Nadia Dowshen Source Type: research

Liver decompensation after rapid weight loss from semaglutide in a patient with non-alcoholic steatohepatitis -associated cirrhosis
We report herein the first documented case of liver decompensation and need for liver transplant waitlisting in a patient with NASH-cirrhosis treated with semaglutide. Rapid weight loss led to the development of ascites and hepatic encephalopathy and an increase in the patients Model for Endstage Liver Disease-Na (MELD-Na) score from 11 to 22. Aggressive nutritional supplementation was commenced and the semaglutide was stopped. Over the following months she regained her weight and her liver recompensated and her MELD-Na decreased to 13, allowing her to be delisted from the transplant waitlist. This case serves as a caution...
Source: World Journal of Gastroenterology : WJG - January 8, 2024 Category: Gastroenterology Authors: Matthew Peverelle Jonathan Ng James Peverelle Ryan D Hirsch Adam Testro Source Type: research

Liver decompensation after rapid weight loss from semaglutide in a patient with non-alcoholic steatohepatitis -associated cirrhosis
We report herein the first documented case of liver decompensation and need for liver transplant waitlisting in a patient with NASH-cirrhosis treated with semaglutide. Rapid weight loss led to the development of ascites and hepatic encephalopathy and an increase in the patients Model for Endstage Liver Disease-Na (MELD-Na) score from 11 to 22. Aggressive nutritional supplementation was commenced and the semaglutide was stopped. Over the following months she regained her weight and her liver recompensated and her MELD-Na decreased to 13, allowing her to be delisted from the transplant waitlist. This case serves as a caution...
Source: World Journal of Gastroenterology - January 8, 2024 Category: Gastroenterology Authors: Matthew Peverelle Jonathan Ng James Peverelle Ryan D Hirsch Adam Testro Source Type: research

Liver decompensation after rapid weight loss from semaglutide in a patient with non-alcoholic steatohepatitis -associated cirrhosis
We report herein the first documented case of liver decompensation and need for liver transplant waitlisting in a patient with NASH-cirrhosis treated with semaglutide. Rapid weight loss led to the development of ascites and hepatic encephalopathy and an increase in the patients Model for Endstage Liver Disease-Na (MELD-Na) score from 11 to 22. Aggressive nutritional supplementation was commenced and the semaglutide was stopped. Over the following months she regained her weight and her liver recompensated and her MELD-Na decreased to 13, allowing her to be delisted from the transplant waitlist. This case serves as a caution...
Source: World Journal of Gastroenterology : WJG - January 8, 2024 Category: Gastroenterology Authors: Matthew Peverelle Jonathan Ng James Peverelle Ryan D Hirsch Adam Testro Source Type: research

Liver decompensation after rapid weight loss from semaglutide in a patient with non-alcoholic steatohepatitis -associated cirrhosis
We report herein the first documented case of liver decompensation and need for liver transplant waitlisting in a patient with NASH-cirrhosis treated with semaglutide. Rapid weight loss led to the development of ascites and hepatic encephalopathy and an increase in the patients Model for Endstage Liver Disease-Na (MELD-Na) score from 11 to 22. Aggressive nutritional supplementation was commenced and the semaglutide was stopped. Over the following months she regained her weight and her liver recompensated and her MELD-Na decreased to 13, allowing her to be delisted from the transplant waitlist. This case serves as a caution...
Source: World Journal of Gastroenterology - January 8, 2024 Category: Gastroenterology Authors: Matthew Peverelle Jonathan Ng James Peverelle Ryan D Hirsch Adam Testro Source Type: research