Is chemical exposure in mothers, babies, linked to poor vaccine response?
Early life exposures to toxic chemicals such as PCBs and DDT dampen an infant's response to the tuberculosis vaccine, according to a new study. PCBs were used in manufacturing and in consumer products in the United States until their ban in 1979. Despite this, nearly all people have detectable concentrations in their blood, even those who live in unindustrialized areas around the globe. DDT, although banned in the U.S., is still used in some countries to control malaria spread by mosquitos. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 9, 2015 Category: Science Source Type: news

Quest for tuberculosis vaccine begins as scientists aim to beat disease by 2035 | Andrew Green
In South Africa and beyond, thousands of TB cases emerge each year despite the BCG vaccine. An ambitious plan seeks to end what has become a global epidemicWhen her son Luluto was born 16 years ago, Yoliswa Qaku was eager to have him vaccinated against tuberculosis. Once he received the injection, she thought, he would be safe from the disease for the rest of his life. She learned earlier this year that this was never the case. Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - December 7, 2015 Category: Science Authors: Andrew Green in Cape Town Tags: Global development Tuberculosis Health Society South Africa World news Medical research Source Type: news

Japan’s GHIT Fund Supports Dartmouth Researchers’ Second Tuberculosis Vaccine Trial
A collaborative of Dartmouth’s Geisel School of Medicine, Muhimbili University of Health and Allied Sciences in Tanzania, and Tokyo Medical and Dental University received $1.4 million from Japan’s Global Health Innovative Technology Fund to conduct a joint randomized clinical trial in Tanzania aimed at reducing the transmission of tuberculosis. (Source: News at Dartmouth Medical School)
Source: News at Dartmouth Medical School - November 5, 2015 Category: Hospital Management Authors: Susan Green Tags: News DarDar Features Ford Von Reyn TB tuberculosis vaccine Source Type: news

Africa: South Africa Plugs TB Vaccine Gap
[News24Wire] Cipla Medpro has entered into an agreement with the Serum Institute of India (SII) to provide South Africans with affordable and accessible vaccines, including BCG which is the only vaccine against tuberculosis (TB). BCG was recently out of stock. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - November 2, 2015 Category: Infectious Diseases Source Type: news

Tuberculosis mortality nearly halved since 1990
The fight against tuberculosis is paying off, with this year’s death rate nearly half of what it was in 1990. Nevertheless, 1.5 million people died from TB in 2014. Most of these deaths could have been prevented, according to WHO’s Global tuberculosis report 2015, which was released today in Washington. To reduce TB’s overall burden, detection and treatment gaps need to be closed, funding shortfalls filled and new diagnostics, drugs and vaccines developed, according to the report. (Source: WHO news)
Source: WHO news - October 28, 2015 Category: Global & Universal Tags: diagnostics [subject], diagnostic procedures, diagnostics, diagnostic imaging, tuberculosis [subject], tb, tuberculosis [subject], tb, vaccines [subject], vaccine, vaccine safety, vaccine quality, vaccines [subject], vaccine, vaccine safety, vaccine quali Source Type: news

Tulane researchers working on new tuberculosis vaccine
(Tulane University) Researchers at the Tulane National Primate Research Center are leading efforts to find a new vaccine for tuberculosis, one of the world's deadliest diseases. A team of researchers led by the TNPRC used a modified strain of TB to show that monkeys could generate better protective immunity than when vaccinated with BCG, a common TB vaccine. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 13, 2015 Category: Infectious Diseases Source Type: news

IDRI, Wellcome Trust team for tuberculosis vaccine trial in South Africa
(Infectious Disease Research Institute) Today, the Infectious Disease Research Institute (IDRI) and Wellcome Trust announce the start of a Phase 2a trial in South Africa of IDRI's tuberculosis vaccine candidate, which has been shown to both prevent and treat TB in preclinical studies in animal models. The Wellcome Trust awarded IDRI a $5.8 million/£3.8 million grant to clinically assess the ability of IDRI's vaccine candidate to reduce TB recurrence after treatment. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 17, 2015 Category: Infectious Diseases Source Type: news

Zimbabwe: BCG Vaccine in Short Supply
[The Herald] Thousands of babies born in recent months could have been exposed to tuberculosis bacteria following a global shortage of the Bacillus Calmette-Guérin (BCG) vaccine. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 7, 2015 Category: African Health Source Type: news

South Africa: Babies At Risk of Contracting TB Due to BCG Vaccine Shortage
[DA] Today I will write to Health Minister Dr Aaron Motsoaledi to call on him to explain to the South African public why we have run out of anti-tuberculosis vaccinations and to reassure us that the problem will not be repeated. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - September 7, 2015 Category: Infectious Diseases Source Type: news

HIQA consulting on changes to BCG vaccine programme
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - September 1, 2015 Category: Drugs & Pharmacology Source Type: news

SLU's vaccine center awarded $2.9 million to study new TB vaccine
(Saint Louis University) Daniel Hoft, M.D., Ph.D., director of the division of infectious diseases at Saint Louis University has received funding from the Gates Foundation to research a potential vaccine against tuberculosis. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 29, 2015 Category: Infectious Diseases Source Type: news

Kenya: Researchers Working to Find Safest, Effective TB Vaccine
[Capital FM] Shanghai -Researchers are now working on a strategy to introduce the safest and most effective Tuberculosis vaccines that reduce the disease worldwide through partnerships and creative mechanisms. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 21, 2015 Category: African Health Source Type: news

New research points to elderly as growing contributor to tuberculosis in China
(Burness Communications) A major contributor to the number of tuberculosis infections and cases in China will likely be the elderly over the next decades, requiring a refocus in efforts to control a disease affecting millions in China, according to preliminary new research presented today at the Fourth Global Forum on TB Vaccines in Shanghai. Researchers from the LSHTM found that developing a 'post-infection' vaccine could reduce overall TB rates in China by almost a third by 2050. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 21, 2015 Category: Global & Universal Source Type: news

Uganda: We Have Enough TB Vaccines - NMS
[Observer]The National Medical Stores (NMS) has dismissed reports of a looming shortage of Bacillus Calmette-Guérin (BCG) vaccines, saying the stocks will last the country until February. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - November 26, 2014 Category: Infectious Diseases Source Type: news

BCG Vaccine Tied to Reduced Hyperglycemia in Type 1 Diabetes
Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Endocrinology, Infections, Nursing, Pathology, Pharmacy, Pulmonology, Journal, Source Type: news