Serum Institute conducting phase III clinical trial of tuberculosis vaccine: DBT
The BCG vaccine is administered routinely to all newborns as part of the national childhood immunisation programme to prevent tuberculosis (TB), an infection caused by bacteria that mainly affects the lungs. It has beneficial heterologous effects and proven antiviral and immune modulatory properties that protect against infectious diseases through induction of trained innate immunity and heterologous adaptive immunity. (Source: The Economic Times)
Source: The Economic Times - July 26, 2020 Category: Consumer Health News Source Type: news
Notes from the Field: Effects of the COVID-19 Response on Tuberculosis Prevention and Control Efforts - United States, March-April 2020
This report describes the importance of continuing to provide resources for tuberculosis testing during the COVID-19 pandemic. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - July 23, 2020 Category: American Health Tags: Coronavirus [CoV] MMWR Morbidity & Mortality Weekly Report Tuberculosis (TB) Tuberculosis Vaccine (BCG) COVID-19 Coronavirus Disease 2019 Source Type: news
Bovine TB vaccine trials get go-ahead in England and Wales
Scientific breakthrough could lead to phasing out of badger culling to tackle diseaseField trials of a cattle vaccine for bovine tuberculosis have been given the go-ahead as part of moves to phase out badger culling to tackle the disease.The trials are due to get under way in England and Wales to accelerate deployment of a cattle vaccine for TB by 2025, the government announced on Wednesday.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - July 22, 2020 Category: Science Authors: PA Media Tags: Bovine tuberculosis Animal welfare Animals Environment Farming Rural affairs UK news Badgers Science Source Type: news
BCG vaccine being tried for Covid-19 elderly individuals in hotspots in India
The study sponsored by the ICMR will recruit 1,450 elderly individuals within the ages of 60 and 99 with no preexisting conditions such as diabetes and will run across six centers in India. The hypothesis for the BCG vaccine comes from studies that have shown that the vaccine — besides protecting children against tuberculosis — also has non-specific effects against other respiratory tract infections. (Source: The Economic Times)
Source: The Economic Times - July 15, 2020 Category: Consumer Health News Source Type: news
TN to launch trial to study efficacy of BCG vaccine to reduce COVID-19 mortality for elders
This is significant as the study will see whether the vaccine ’s potential to combat Covid-19 and prevent hospitalisation among the aged as they are more susceptible to picking up the infection as they often suffer from co-morbid conditions. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 14, 2020 Category: Pharmaceuticals Source Type: news
Evidence Shows TB Vaccine May Help Versus COVID-19
Developing countries have lower-than-expected COVID-19 death rates, and a TB vaccine given in countries with high rates of tuberculosis might play a significant role in reducing COVID-19 death rates. (Source: WebMD Health)
Source: WebMD Health - July 13, 2020 Category: Consumer Health News Source Type: news
Evidence Mounts That TB Vaccine Might Help Protect Against COVID-19
MONDAY, July 13, 2020 -- A tuberculosis vaccine may help reduce the risk of death from COVID-19, researchers suggest.
Developing countries have lower-than-expected COVID-19 death rates, and a TB vaccine given in countries with high rates of... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 13, 2020 Category: General Medicine Source Type: news
More evidence emerges that a TB vaccine might help fight coronavirus
More research emerged this week in potential support of using the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) as a tool in the fight against coronavirus. (Source: CNN.com - Health)
Source: CNN.com - Health - July 10, 2020 Category: Consumer Health News Source Type: news
Preliminary study suggests tuberculosis vaccine may be limiting COVID-19 deaths
(Virginia Tech) While a direct correlation between BCG vaccinations and a reduction in coronavirus mortalities still needs to be understood more fully, researchers hold hope that the BCG vaccine might be able to provide at least short-term protections against severe COVID-19, particularly for front-line medical workers or high-risk patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 8, 2020 Category: International Medicine & Public Health Source Type: news
Janssen Announces Discontinuation of Phase 3 LOTUS Study Evaluating Ustekinumab in Systemic Lupus Erythematosus
SPRING HOUSE, PENNSYLVANIA, June 26, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today its decision to discontinue the Phase 3 LOTUS study of STELARA® (ustekinumab) in Systemic Lupus Erythematosus (SLE) due to lack of efficacy in SLE.The decision is based on data from a pre-planned interim efficacy analysis. Interim safety findings were consistent with the known safety profile of STELARA, and no new safety signals were identified. Investigators, study participants and health authorities have been informed of the decision. The company intends to thoroughly analyze the totality of the st...
Source: Johnson and Johnson - June 26, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news
South Africa: New Multi-Functional TB Blood Test Validated
[UCT] Researchers from the South African Tuberculosis Vaccine Initiative (SATVI) at the University of Cape Town (UCT), the Center for Global Infectious Disease Research - Seattle in the United States, and a large consortium of collaborators have developed a validated a new, simple blood-based test that has the potential to serve multiple functions in the fight against TB. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - May 25, 2020 Category: Infectious Diseases Source Type: news
A Vaccine Against COVID-19 Would Be the Latest Success in a Long Scientific History
Here’s betting you wouldn’t want anyone blowing smallpox scabs up your nose. But you might feel differently if you lived in 15th century China.
Long ago, the Chinese recognized that people who had contracted smallpox once were immune to reinfection. They came up with the idea of preserving scabs from individuals who had suffered mild cases, drying them out, crushing them to a powder and blowing them up the nostril. For boys it was the right nostril, for girls it was the left because, well, 15th century.
That is how the story of vaccines usually begins, though that version is decidedly incomplete. For one thing,...
Source: TIME: Science - May 15, 2020 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized COVID-19 Explainer health Source Type: news
Africa: Could BCG, a 100-Year-Old Vaccine for Tuberculosis, Protect Against Coronavirus?
[IPS] This week, the Bill and Melinda Gates Foundation announced it will donate A$10 million to help fund an Australian trial testing whether a very old vaccine, BCG, can be used against a new threat, COVID-19. So what is the BCG vaccine and what might its place be in the fight against coronavirus? (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - May 15, 2020 Category: Infectious Diseases Source Type: news
Could BCG, a 100-year-old Vaccine for Tuberculosis, Protect Against Coronavirus?
This article is republished from The Conversation under a Creative Commons license. Read the original article.
The post Could BCG, a 100-year-old Vaccine for Tuberculosis, Protect Against Coronavirus? appeared first on Inter Press Service. (Source: IPS Inter Press Service - Health)
Source: IPS Inter Press Service - Health - May 14, 2020 Category: International Medicine & Public Health Authors: External Source Tags: Global Headlines Health Source Type: news
Mandatory BCG vaccination may make COVID-19 less virulent in India, suggests study
The bacille Calmette-Gurin (BCG) vaccine has a documented protective effect against meningitis and disseminated TB in children, according to the World Health Organisation. It is part of the mandatory childhood immunization programme in many countries including India. (Source: The Economic Times)
Source: The Economic Times - May 7, 2020 Category: Consumer Health News Source Type: news
