Breakthrough For Tuberculosis —One Of The World’s Biggest Killers—As New Vaccine Shows Promise In Early Trials
Tuberculosis is one of humanity ’s biggest killers and the only licensed TB vaccine, BCG, was developed more than 100 years ago. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 6, 2023 Category: Pharmaceuticals Authors: Robert Hart, Forbes Staff Tags: Business /business Innovation /innovation Science /science Healthcare /healthcare Breaking breaking-news Source Type: news

New STELARA ® (ustekinumab) Long-Term Data Support its Established Safety Profile in Inflammatory Bowel Disease and Durable Efficacy in Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, March 4, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced final pooled long-term safety results for STELARA® (ustekinumab) through five years in adults with moderately to severely active Crohn’s disease (CD) and four years in adults with moderately to severely active ulcerative colitis (UC), as well as final four-year clinical and endoscopic outcomes from the UNIFI long-term extension (LTE) study evaluating the efficacy of STELARA for the treatment of adults with moderately to severely active UC.1,2 These data are a part of Janssen’s 22 oral and poster ...
Source: Johnson and Johnson - March 4, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

BCG Vaccine Flops for Preventing COVID, Other Respiratory Infections
(MedPage Today) -- The bacillus Calmette-Guérin (BCG) vaccine failed to protect against COVID-19 and other respiratory tract infections (RTIs) among older adults with comorbidities, according to a randomized trial from The Netherlands. In... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - February 3, 2023 Category: Infectious Diseases Source Type: news

Persistent pollutants linked to poor vaccine response
<img width="100" src="https://factor.niehs.nih.gov/sites/niehs-factor/files/styles/large/public/2016/1/papers/pollutants/thumb772767.jpg?itok=UvAgOEvO" /><br /><p>New research indicates that exposure to pollutants such as DDT and PCBs may dampen infants’ immune response to the tuberculosis vaccine.</p> (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - February 3, 2023 Category: Environmental Health Source Type: news

Sierra Leone: WHO to Establish TB Vaccine Council
[Concord] Director General of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus has announced plans to establish a new TB Vaccine Accelerator Council. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 20, 2023 Category: African Health Source Type: news

WHO announces plans to establish a TB Vaccine Accelerator council
The adverse impact of the COVID-19 pandemic on tuberculosis (TB) services has brought the urgency of vaccine development efforts into sharp focus. Speaking earlier today at a high-level panel on TB at the World Economic Forum, Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization, announced plans to establish a new TB Vaccine Accelerator Council. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 19, 2023 Category: Consumer Health News Source Type: news

Africa: WHO Announces Plans to Establish a TB Vaccine Accelerator Council
[WHO] The adverse impact of the COVID-19 pandemic on tuberculosis (TB) services has brought the urgency of vaccine development efforts into sharp focus. Speaking earlier today at a high-level panel on TB at the World Economic Forum, Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization, announced plans to establish a new TB Vaccine Accelerator Council. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - January 18, 2023 Category: Infectious Diseases Source Type: news

Africa: WHO Launches Council to Develop TB Vaccines
[UN News] The head of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus, has unveiled plans to speed up the licensing and use of effective novel vaccines against tuberculosis (TB), the second leading infectious killer after COVID-19 and the 13th leading cause of death worldwide. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 18, 2023 Category: African Health Source Type: news

South Africa: South African Researchers Break New Ground in TB Vaccine Research - South African News Briefs - January 12, 2023
[allAfrica] Cape Town -- South African Researchers Bring Hope for Developing New TB Vaccines (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - January 12, 2023 Category: Infectious Diseases Source Type: news

Clinical trials of new BCG vaccine for TB to start soon, says former CSIR chief
According to the India TB Report 2022, the number of 'incident TB patients' (new and relapse cases) notified during 2021 stood at 19.3 lakh. On the government's aim to make India TB-free by 2025, former director-general of the CSIR Dr Shekhar Mande said, "There is a very serious effort going across various agencies in the country. The department of health research, department of bio-technologies, CSIR, all of them are working towards TB-free 2025." (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - January 6, 2023 Category: Pharmaceuticals Source Type: news

Serum Institute seeks nod for adult TB vaccine
Once the drug controller approves the vaccine, the national technical advisory group on immunisation (NTAGI) will take a final call in its introduction in the immunisation programme. TUBERVAC-rBCG vaccine can be given to children, adolescents and adults. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 12, 2022 Category: Pharmaceuticals Source Type: news

Infant BCG Vaccine Protects Only Those Under Age 5 Years Infant BCG Vaccine Protects Only Those Under Age 5 Years
Although the BCG vaccine may keep severe forms of tuberculosis, meningitis, and miliary tuberculosis at bay, its efficacy and effectiveness against pulmonary tuberculosis are low.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - December 5, 2022 Category: Allergy & Immunology Tags: Infectious Diseases News Source Type: news

STELARA ® (ustekinumab) Demonstrated Sustained Symptomatic and Corticosteroid-Free Remission Through Four Years in Adults with Moderately to Severely Active Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 10, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced final data from the long-term extension (LTE) of the Phase 3 UNIFI study demonstrating efficacy and safety of STELARA® (ustekinumab) through four years of treatment in adult patients with moderately to severely active ulcerative colitis (UC).1 Among all patients who had achieved clinical responsea with STELARA during induction, 64.9 percent were in symptomatic remissionb after 44 weeks of maintenance. At week 200 (four years), this proportion of patients was 55.2 percent; the majority (96.4 percen...
Source: Johnson and Johnson - October 10, 2022 Category: Pharmaceuticals Source Type: news

Multidose BCG Protects Against COVID-19 in At-Risk Individuals
TUESDAY, Aug. 16, 2022 -- The multidose Bacillus Calmette-Guerin (BCG) vaccine offers protection against COVID-19 infection among COVID-19-unvaccinated individuals with type 1 diabetes, according to a study published online Aug. 15 in Cell Reports... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 16, 2022 Category: Pharmaceuticals Source Type: news

Why a Century-Old Vaccine Offers New Hope Against Pathogens
The B.C.G. tuberculosis vaccine may protect against Covid-19 and other infections by broadly bolstering the immune system. (Source: NYT Health)
Source: NYT Health - August 16, 2022 Category: Consumer Health News Authors: Roni Caryn Rabin Tags: your-feed-science Clinical Trials Diabetes Vaccination and Immunization Immune System Tuberculosis Coronavirus (2019-nCoV) Source Type: news