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Size-exclusion chromatography selective cleanup of aflatoxins in oilseeds followed by HPLC determination to assess the potential health risk
In this study, a proposed testing method for AF detection in oilseed was developed, validated, and used for a market survey to assess the probabilistic risk exposure caused by consuming contaminated oilseeds including corn, sunflower seed, and soybean. The test method was optimized for selective extraction and then validated for fitness of purpose; the limits of quantification (LOQs) were 0.2, 0.4, 0.2, and 0.2 μg kg-1 for aflatoxin G1 (AFG1), aflatoxin B1 (AFB1), aflatoxin G2 (AFG2), and aflatoxin B2 (AFB2), respectively. The method was linear from the LOQs up to 20 μg kg-1, and its budget of measurement uncertainties w...
Source: Toxicon - July 19, 2021 Category: Toxicology Authors: Omar Tawfik Kholif Ahmed Salem Sebaei Fawzy I Eissa Osama H Elhamalawy Source Type: research

Molecules, Vol. 26, Pages 3939: Development of a High-Fibre Multigrain Bar Technology with the Addition of Curly Kale
�c Agata Marzec The aim of this study was to find the effect of kale and dietary fibre (DF) on the physicochemical properties, nutritional value and sensory quality of multigrain bars. A recipe of multigrain bars was prepared with the addition of fresh kale (20% and 30%) and DF preparations (apple, blackcurrant, chokeberry and hibiscus). The bars were baked at 180 °C for 20 min. These snack bars, based on pumpkin seeds, sunflower seeds, flaxseed and wholegrain oatmeal, are a high-calorie product (302–367 kcal/100 g). However, the composition of the bars encourages consumption. In addition to the ability to quickly...
Source: Molecules - June 28, 2021 Category: Chemistry Authors: Hanna Kowalska Jolanta Kowalska Anna Ignaczak Ewelina Masiarz Ewa Domian Sabina Galus Agnieszka Ciurzy ńska Agnieszka Salamon Agnieszka Zaj ąc Agata Marzec Tags: Article Source Type: research

[ASAP] Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.1c00158 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 23, 2021 Category: Chemistry Authors: Edin Muratspahic ́, Nataša Tomašević, Johannes Koehbach, Leopold Duerrauer, Seid Hadžić, Joel Castro, Gudrun Schober, Spyridon Sideromenos, Richard J. Clark, Stuart M. Brierley, David J. Craik, and Christian W. Gruber Source Type: research

Estimation of Tolerable Daily Intake (TDI) for Immunological Effects of Aflatoxin
AbstractAflatoxins are toxic chemicals produced by the fungiAspergillus flavus andAspergillus parasiticus. In warm climates, these fungi frequently contaminate crops such as maize, peanuts, tree nuts, and sunflower seeds. In many tropical and subtropical regions of the world, populations are coexposed to dietary aflatoxin and multiple infectious pathogens in food, water, and the environment. There is increasing evidence that aflatoxin compromises the immune system, which could increase infectious disease risk in vulnerable populations. Our aim was to conduct a dose –response assessment on a noncarcinogenic endpoint of af...
Source: Risk Analysis - June 19, 2021 Category: International Medicine & Public Health Authors: Nikita Saha Turna, Felicia Wu Tags: Perspective Source Type: research

Cardiac contractile dysfunction, during and following ischaemia, is attenuated by low-dose dietary fish oil in rats
ConclusionIschaemia-induced contractile dysfunction in rats is limited from fish oil doses equivalent to regular consumption of fish in the human diet. These observations highlight plausible and clinically relevant physiological changes that rationalise nutritional conditioning of the heart with DHA for on-going cardioprotection. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - June 13, 2021 Category: Nutrition Source Type: research

Effect of topical applications of sunflower seed oil on systemic fatty acid levels in under-two children under rehabilitation for severe acute malnutrition in Bangladesh: a randomized controlled trial
Children with severe acute malnutrition (SAM) have inadequate levels of fatty acids (FAs) and limited capacity for enteral nutritional rehabilitation. We hypothesized that topical high-linoleate sunflower seed... (Source: Nutrition Journal)
Source: Nutrition Journal - June 6, 2021 Category: Nutrition Authors: K. M. Shahunja, Daniel C. S évin, Lindsay Kendall, Tahmeed Ahmed, Md. Iqbal Hossain, Mustafa Mahfuz, Xinyi Zhu, Krishan Singh, Sunita Singh, Jonathan M. Crowther, Rachel A. Gibson and Gary L. Darmstadt Tags: Research Source Type: research

Anaphylaxis to Sunflower Seed with Tolerance to Other Nuts. The Role of Lipophilic Allergens
J Investig Allergol Clin Immunol. 2021 May 27:0. doi: 10.18176/jiaci.0710. Online ahead of print.NO ABSTRACTPMID:34045176 | DOI:10.18176/jiaci.0710 (Source: Journal of Investigational Allergology and Clinical Immunology)
Source: Journal of Investigational Allergology and Clinical Immunology - May 28, 2021 Category: Allergy & Immunology Authors: L Gonz ález-Bravo J Laiseca-Garc ía F Pineda A Rosado Source Type: research

Impact of emollient therapy for preterm infants in the neonatal period on child neurodevelopment in Bangladesh: an observational cohort study
CONCLUSIONS: Emollient massage of very preterm, hospitalized newborn infants improved some child neurodevelopmental outcomes over the first 2 years of follow-up. Findings warrant further confirmatory research.TRIAL REGISTRATION: ClinicalTrials.gov (98-04-21-03-2) under weblink https://clinicaltrials.gov/ct2/show/NCT00162747.PMID:34039435 | PMC:PMC8152128 | DOI:10.1186/s41043-021-00248-9 (Source: Journal of Health, Population, and Nutrition)
Source: Journal of Health, Population, and Nutrition - May 27, 2021 Category: International Medicine & Public Health Authors: Gary L Darmstadt Naila Z Khan Summer Rosenstock Humaira Muslima Monowara Parveen Wajeeha Mahmood A S M Nawshad Uddin Ahmed M A K Azad Chowdhury Scott Zeger Samir K Saha Source Type: research

Impact of emollient therapy for preterm infants in the neonatal period on child neurodevelopment in Bangladesh: an observational cohort study
CONCLUSIONS: Emollient massage of very preterm, hospitalized newborn infants improved some child neurodevelopmental outcomes over the first 2 years of follow-up. Findings warrant further confirmatory research.TRIAL REGISTRATION: ClinicalTrials.gov (98-04-21-03-2) under weblink https://clinicaltrials.gov/ct2/show/NCT00162747.PMID:34039435 | DOI:10.1186/s41043-021-00248-9 (Source: Journal of Health, Population, and Nutrition)
Source: Journal of Health, Population, and Nutrition - May 27, 2021 Category: International Medicine & Public Health Authors: Gary L Darmstadt Naila Z Khan Summer Rosenstock Humaira Muslima Monowara Parveen Wajeeha Mahmood A S M Nawshad Uddin Ahmed M A K Azad Chowdhury Scott Zeger Samir K Saha Source Type: research