IGF1 promotes human myotube differentiation toward a mature metabolic and contractile phenotype
Am J Physiol Cell Physiol. 2024 Mar 4. doi: 10.1152/ajpcell.00654.2023. Online ahead of print.ABSTRACTSkeletal muscle mediates the beneficial effects of exercise, thereby improving insulin sensitivity and reducing the risk for type 2 diabetes. Current human skeletal muscle models in vitro are incapable of fully recapitulating its physiological functions especially muscle contractility. By supplementation of insulin-like growth factor 1 (IGF1), a growth factor secreted by myofibers in vivo, we aimed to overcome these limitations. We monitored the differentiation process starting from primary human CD56-positive myoblasts in...
Source: Am J Physiol Cell Ph... - May 1, 2024 Category: Cytology Authors: Simon I Dreher Paul Grubba Christine von Toerne Alessia Moruzzi Jennifer Maurer Thomas Goj Andreas L Birkenfeld Andreas Peter Peter Loskill Stefanie M Hauck Cora Weigert Source Type: research
IGF1 promotes human myotube differentiation toward a mature metabolic and contractile phenotype
Am J Physiol Cell Physiol. 2024 Mar 4. doi: 10.1152/ajpcell.00654.2023. Online ahead of print.ABSTRACTSkeletal muscle mediates the beneficial effects of exercise, thereby improving insulin sensitivity and reducing the risk for type 2 diabetes. Current human skeletal muscle models in vitro are incapable of fully recapitulating its physiological functions especially muscle contractility. By supplementation of insulin-like growth factor 1 (IGF1), a growth factor secreted by myofibers in vivo, we aimed to overcome these limitations. We monitored the differentiation process starting from primary human CD56-positive myoblasts in...
Source: American Journal of Physiology. Cell Physiology - May 1, 2024 Category: Cytology Authors: Simon I Dreher Paul Grubba Christine von Toerne Alessia Moruzzi Jennifer Maurer Thomas Goj Andreas L Birkenfeld Andreas Peter Peter Loskill Stefanie M Hauck Cora Weigert Source Type: research
Effectiveness of Resistance Band Use in Conjunction With Tai Chi Among Older Adults With Prefrailty to Improve Functional Fitness, Quality of Life, and Heart Rate Variability
CONCLUSION: Results revealed substantial improvements in physical fitness, frailty conditions, self-care abilities, and quality of life, but not balance or lower limb flexibility, for the experimental group. Therefore, exercise interventions may effectively improve prefrail older adults' quality of life. [Journal of Gerontological Nursing, 50(5), 19-26.].PMID:38691121 | DOI:10.3928/00989134-20240416-04 (Source: Journal of Gerontological Nursing)
Source: Journal of Gerontological Nursing - May 1, 2024 Category: Nursing Authors: Shan-Che Woo Miao-Yen Chen Liang-Kung Chen Chieh-Yu Liu Source Type: research
The cardiovascular system at high altitude: A bibliometric and visualization analysis
CONCLUSION: Over the past 32 years, research on the cardiovascular system in high-altitude regions has been steadily increasing. Future research in this field may focus on areas such as hypoxia adaptation, metabolism, and cardiopulmonary exercise. Strengthening interdisciplinary and multi-team collaborations will facilitate further exploration of the pathophysiological mechanisms underlying cardiovascular changes in high-altitude environments and provide a theoretical basis for standardized disease diagnosis and treatment.PMID:38690218 | PMC:PMC11056872 | DOI:10.4330/wjc.v16.i4.199 (Source: World Journal of Cardiology)
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Mao-Lin Zhao Zhong-Jie Lu Li Yang Sheng Ding Feng Gao Yuan-Zhang Liu Xue-Lin Yang Xia Li Si-Yi He Source Type: research
IGF1 promotes human myotube differentiation toward a mature metabolic and contractile phenotype
Am J Physiol Cell Physiol. 2024 Mar 4. doi: 10.1152/ajpcell.00654.2023. Online ahead of print.ABSTRACTSkeletal muscle mediates the beneficial effects of exercise, thereby improving insulin sensitivity and reducing the risk for type 2 diabetes. Current human skeletal muscle models in vitro are incapable of fully recapitulating its physiological functions especially muscle contractility. By supplementation of insulin-like growth factor 1 (IGF1), a growth factor secreted by myofibers in vivo, we aimed to overcome these limitations. We monitored the differentiation process starting from primary human CD56-positive myoblasts in...
Source: American Journal of Physiology. Cell Physiology - May 1, 2024 Category: Cytology Authors: Simon I Dreher Paul Grubba Christine von Toerne Alessia Moruzzi Jennifer Maurer Thomas Goj Andreas L Birkenfeld Andreas Peter Peter Loskill Stefanie M Hauck Cora Weigert Source Type: research
IGF1 promotes human myotube differentiation toward a mature metabolic and contractile phenotype
Am J Physiol Cell Physiol. 2024 Mar 4. doi: 10.1152/ajpcell.00654.2023. Online ahead of print.ABSTRACTSkeletal muscle mediates the beneficial effects of exercise, thereby improving insulin sensitivity and reducing the risk for type 2 diabetes. Current human skeletal muscle models in vitro are incapable of fully recapitulating its physiological functions especially muscle contractility. By supplementation of insulin-like growth factor 1 (IGF1), a growth factor secreted by myofibers in vivo, we aimed to overcome these limitations. We monitored the differentiation process starting from primary human CD56-positive myoblasts in...
Source: Am J Physiol Cell Ph... - May 1, 2024 Category: Cytology Authors: Simon I Dreher Paul Grubba Christine von Toerne Alessia Moruzzi Jennifer Maurer Thomas Goj Andreas L Birkenfeld Andreas Peter Peter Loskill Stefanie M Hauck Cora Weigert Source Type: research
The relationship between T7-Fz alpha coherence and peak performance in self-paced sports: a meta-analytical review
We examined whether the alpha-band coherence between the T7-Fz (verbal analytical-motor planning) brain areas were related to superior performance in sports. We searched for related papers across eight databases: ProQuest Central, ProQuest Psychology Journals, PsycARTICLES, PsycINFO, SPORTDiscus, MEDLINE, Scopus, and Web of Science using relevant keywords (i.e., EEG AND sports AND coherence). Seven studies, with a total of 194 participants, met our inclusion criteria and were shortlisted for statistical analysis. We compared EEG coherence data for both within-subject and between-subject experimental designs. Our analysis r...
Source: Experimental Brain Research - May 1, 2024 Category: Neuroscience Authors: Dhruv Raman Edson Filho Source Type: research
Estimation of Vertical Ground Reaction Force during Single-leg Landing Using Two-dimensional Video Images and Pose Estimation Artificial Intelligence
CONCLUSION: The results of this study indicate that peak VGRF estimation using 2D video images and pose estimation AI is useful for the clinical assessment of single-leg landing.PMID:38690532 | PMC:PMC11057390 | DOI:10.1298/ptr.E10276 (Source: Physical Therapy)
Source: Physical Therapy - May 1, 2024 Category: Physiotherapy Authors: Tomoya Ishida Takumi Ino Yoshiki Yamakawa Naofumi Wada Yuta Koshino Mina Samukawa Satoshi Kasahara Harukazu Tohyama Source Type: research
Effects of Isometric Quadriceps Muscle Exercise with Visual and Auditory Feedback at 1 Year after Total Knee Arthroplasty
CONCLUSIONS: These results suggest that performing isometric quadriceps exercise with visual and auditory feedback using the quadriceps training machine has good effects, such as pain reduction, physical function improvement, exercise tolerance, and increased physical activity at 1 year after TKA.PMID:38690528 | PMC:PMC11057392 | DOI:10.1298/ptr.E10260 (Source: Physical Therapy)
Source: Physical Therapy - May 1, 2024 Category: Physiotherapy Authors: Yasutaka Kondo Yoshihiro Yoshida Takashi Iioka Hideki Kataoka Junya Sakamoto Yuichiro Honda Atsushi Nawata Minoru Okita Source Type: research
Estimation of Vertical Ground Reaction Force during Single-leg Landing Using Two-dimensional Video Images and Pose Estimation Artificial Intelligence
CONCLUSION: The results of this study indicate that peak VGRF estimation using 2D video images and pose estimation AI is useful for the clinical assessment of single-leg landing.PMID:38690532 | PMC:PMC11057390 | DOI:10.1298/ptr.E10276 (Source: Health Physics)
Source: Health Physics - May 1, 2024 Category: Physics Authors: Tomoya Ishida Takumi Ino Yoshiki Yamakawa Naofumi Wada Yuta Koshino Mina Samukawa Satoshi Kasahara Harukazu Tohyama Source Type: research
Effects of Isometric Quadriceps Muscle Exercise with Visual and Auditory Feedback at 1 Year after Total Knee Arthroplasty
CONCLUSIONS: These results suggest that performing isometric quadriceps exercise with visual and auditory feedback using the quadriceps training machine has good effects, such as pain reduction, physical function improvement, exercise tolerance, and increased physical activity at 1 year after TKA.PMID:38690528 | PMC:PMC11057392 | DOI:10.1298/ptr.E10260 (Source: Health Physics)
Source: Health Physics - May 1, 2024 Category: Physics Authors: Yasutaka Kondo Yoshihiro Yoshida Takashi Iioka Hideki Kataoka Junya Sakamoto Yuichiro Honda Atsushi Nawata Minoru Okita Source Type: research
Effectiveness of Resistance Band Use in Conjunction With Tai Chi Among Older Adults With Prefrailty to Improve Functional Fitness, Quality of Life, and Heart Rate Variability
CONCLUSION: Results revealed substantial improvements in physical fitness, frailty conditions, self-care abilities, and quality of life, but not balance or lower limb flexibility, for the experimental group. Therefore, exercise interventions may effectively improve prefrail older adults' quality of life. [Journal of Gerontological Nursing, 50(5), 19-26.].PMID:38691121 | DOI:10.3928/00989134-20240416-04 (Source: Journal of Gerontological Nursing)
Source: Journal of Gerontological Nursing - May 1, 2024 Category: Nursing Authors: Shan-Che Woo Miao-Yen Chen Liang-Kung Chen Chieh-Yu Liu Source Type: research
The relationship between T7-Fz alpha coherence and peak performance in self-paced sports: a meta-analytical review
We examined whether the alpha-band coherence between the T7-Fz (verbal analytical-motor planning) brain areas were related to superior performance in sports. We searched for related papers across eight databases: ProQuest Central, ProQuest Psychology Journals, PsycARTICLES, PsycINFO, SPORTDiscus, MEDLINE, Scopus, and Web of Science using relevant keywords (i.e., EEG AND sports AND coherence). Seven studies, with a total of 194 participants, met our inclusion criteria and were shortlisted for statistical analysis. We compared EEG coherence data for both within-subject and between-subject experimental designs. Our analysis r...
Source: Brain Research - May 1, 2024 Category: Neurology Authors: Dhruv Raman Edson Filho Source Type: research
The Evaluation and Management of Concussion to Optimize Safe Recovery
Prim Care. 2024 Jun;51(2):269-282. doi: 10.1016/j.pop.2024.02.009. Epub 2024 Mar 23.ABSTRACTConcussion is a mild traumatic brain injury causing temporary neurologic dysfunction. Symptoms following concussion are variable and generally are expected to resolve within about 1 month, but some patients experience persistent and prolonged symptoms. An early return to safe, symptom-limited activity is now favored, using targeted rehabilitation and treatments. Accommodations may be needed to facilitate return-to-school and work following concussion. Athletes should not be cleared for a full return to sport until they have recovere...
Source: Primary Care - May 1, 2024 Category: Primary Care Authors: Mark Roberts Michael Popovich Andrea Almeida Source Type: research
The relationship between T7-Fz alpha coherence and peak performance in self-paced sports: a meta-analytical review
We examined whether the alpha-band coherence between the T7-Fz (verbal analytical-motor planning) brain areas were related to superior performance in sports. We searched for related papers across eight databases: ProQuest Central, ProQuest Psychology Journals, PsycARTICLES, PsycINFO, SPORTDiscus, MEDLINE, Scopus, and Web of Science using relevant keywords (i.e., EEG AND sports AND coherence). Seven studies, with a total of 194 participants, met our inclusion criteria and were shortlisted for statistical analysis. We compared EEG coherence data for both within-subject and between-subject experimental designs. Our analysis r...
Source: Experimental Brain Research - May 1, 2024 Category: Neuroscience Authors: Dhruv Raman Edson Filho Source Type: research
