Your headaches are getting worse. Do you need an imaging test?
Headache is a very common condition that affects up to 60% of the world’s population. In general, headache can be classified into two main categories: primary and secondary headaches. A primary headache is related to increased sensitivities, but not structural alterations of brain tissues. Common primary headaches are migraine with and without aura, tension-type headache, and trigeminal autonomic cephalalgias (headaches, such as cluster headache, that also involve facial pain and autonomic symptoms such as tear production and nasal congestion). Secondary headaches have various underlying causes including structural vascu...
Source: Harvard Health Blog - May 7, 2020 Category: Consumer Health News Authors: Hsinlin Thomas Cheng, MD, PhD Tags: Headache Tests and procedures Source Type: blogs
Soft Actuator and Sensor for Underactive Bladder Treatment
Researchers at the National University of Singapore have developed a soft sensor and actuator to monitor bladder volume and help empty it on-demand. The device is intended to be implanted on the bladder surface during a surgical procedure to treat patients who cannot completely empty their bladders voluntarily.
Patients can suffer from an underactive bladder following a spinal cord injury, meaning that they cannot easily sense when the bladder is full, or completely empty it. Approximately 80% of patients who suffer a spinal cord injury will demonstrate some bladder dysfunction. Not only is this inconvenient and upsetti...
Source: Medgadget - May 6, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Neurology Rehab Surgery Source Type: blogs
Brain-Computer Interface Lets Man with Complete Spinal Cord Injury Feel and Move His Hand
Spinal cord injuries can leave people paralyzed and without a sense of touch in much of the body. While there’s been a tremendous amount of work in the past decade to overcome paralysis by using brain-computer interfaces to bypass damaged spinal cords, providing a sense of touch is a necessity for truly proper treatment. As anyone with peripheral neuropathy knows, not being able to feel one’s hands and feet makes it difficult to grab and manipulate physical objects.
Now, researchers from Battelle and The Ohio State University Wexner Medical Center are reporting that a man with clinically complete spinal cord...
Source: Medgadget - April 28, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Neurology Neurosurgery Rehab Source Type: blogs
On World Health Day 2020, let ’s discuss the stress response and the General Adaptation Syndrome (2/3)
The hypothalamus–pituitary–adrenal (HPA) axis acts to release cortisol into the blood stream, as cortisol calls the body into action to combat stress. When high amounts of cortisol interact with the hypothalamus, the HPA axis will slow down its activity. The amygdala detects stress, while the prefrontal cortex regulates our reactions to stress. Source: Bezdek K and Telzer E (2017) Have No Fear, the Brain is Here! How Your Brain Responds to Stress. Front. Young Minds. 5:71. doi: 10.3389/frym.2017.00071
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[Editor’s note: Continued from yesterday’s Exploring the human brain and how it responds to stress (1/3)]
S...
Source: SharpBrains - April 7, 2020 Category: Neuroscience Authors: Dr. Jerome Schultz Tags: Cognitive Neuroscience Education & Lifelong Learning Health & Wellness #WorldHealthDay brain burnout cognition Cortisol GAS General Adaptation Syndrome homeostasis memory neurobiology neurological exhaustion Stress Source Type: blogs
BiWaze Cough System Receives FDA Clearance to Help Clear Secretions
ABM Respiratory Care, a company with offices in USA, Singapore, and India, announced that it has received FDA 510(k) clearance to market its BiWaze Cough System, a device for removing secretions in patients who are unable to cough or clear secretions effectively.
The BiWaze Cough System consists of a touch-screen device connected to a non-invasive suctioning mask. It is a portable alternative to the invasive and more involved process of upper airway suctioning. The system also provides high frequency oscillations, between 5-20 Hz, to break up thick secretions and facilitate their removal from the lungs.
The touc...
Source: Medgadget - April 2, 2020 Category: Medical Devices Authors: Cici Zhou Tags: Cardiology Medicine Neurology Pediatrics Source Type: blogs
Fight Aging! Newsletter, March 16th 2020
We report a new class of natural-product-inspired covalent inhibitors of telomerase that target the catalytic active site.
Age-Related Epigenetic Changes that Suppress Mitochondrial Function
https://www.fightaging.org/archives/2020/03/age-related-epigenetic-changes-that-suppress-mitochondrial-function/
Today's open access research reports on two specific epigenetic changes observed in old individuals that act to reduce mitochondrial function. This joins an existing list of genes for which expression changes are known to impact mitochondrial function with age. A herd of hundreds of mitochondria are found...
Source: Fight Aging! - March 15, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Improving Mitochondrial Function in Neurons to Boost Nerve Regeneration
Mitochondria are the power plants of the cell, responsible for producing the chemical energy store molecule adenosine triphosphate (ATP) that powers cellular operations. As such, most processes of interest in disease and regeneration have at least some indirect dependency on mitochondrial function. Researchers here note a potential connection between mitochondrial function and the inability of nerves to regrow following injury. They provide evidence for an adjustment to the way in which mitochondria behave in nerve cells, and in the connections between nerve cells called axons, to spur regeneration. This is an interesting ...
Source: Fight Aging! - March 10, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
10 Ways Technology Is Changing Healthcare
The future of healthcare is shaping up in front of our very eyes with advances in digital technologies, such as artificial intelligence, VR/AR, 3D-printing, robotics or nanotechnology. We have to familiarize with the latest developments in order to be able to control technology and not the other way around. The future of healthcare lies in working hand-in-hand with technology and healthcare workers have to embrace emerging technologies in order to stay relevant in the coming years.
Be bold, curious and informed!
Are you afraid that robots will take over the jobs of nurses, doctors and other healthcare professionals? Are y...
Source: The Medical Futurist - March 3, 2020 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine 3d printing AI artificial intelligence augmented reality genetics Health Healthcare nanotechnology Personalized medicine pharma pharmacology robotics virtual reality wearables GC1 Source Type: blogs
Fight Aging! Newsletter, February 24th 2020
In conclusion, taller body height at the entry to adulthood, supposed to be a marker of early-life environment, is associated with lower risk of dementia diagnosis later in life. The association persisted when adjusted for educational level and intelligence test scores in young adulthood, suggesting that height is not just acting as an indicator of cognitive reserve.
A Comparison of Biological Age Measurement Approaches
https://www.fightaging.org/archives/2020/02/a-comparison-of-biological-age-measurement-approaches/
Researchers here assess the performance of a range of approaches to measuring biologica...
Source: Fight Aging! - February 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
VOCSN 5-in-1 Portable Ventilator: Interview with Chris Kiple, CEO of Ventec
Ventilators are used by patients who lose lung function due to complications from a variety of diseases such as spinal cord injuries, COPD, stroke, pneumonia, and ALS. In addition to dealing with a debilitating situation, patients tend to be hooked to several machines that perform mechanical ventilation, oxygen delivery, cough assist, suction, and nebulization. This typically involves wires running all around, multiple software, and hardware equipment that makes it difficult for caregivers to operate the machines and provide quality care. Ventec Life Systems simplifies this experience by offering an integrated ventilator s...
Source: Medgadget - February 19, 2020 Category: Medical Devices Authors: Rukmani Sridharan Tags: Cardiology Critical Care Exclusive Medicine Pediatrics Rehab Source Type: blogs
Activating Quiescent ILC2 Immune Cells in the Aging Mouse Brain Improves Cognitive Function
In this study, we report the accumulation of tissue-resident ILC2 in the choroid plexus of the aged brain, with ILC2 comprising a major subset of lymphocytes in the choroid plexus of aged mice and humans. ILC2 in the aged brain are long-lived and capable of reversibly switching between cell cycle dormancy and proliferation. They are relatively resistant to cellular senescence and exhaustion under replication stress, leading to enhanced self-renewal capability. They are functionally quiescent at homeostasis but can be activated by exogenous IL-33 to produce large amounts of IL-5 and IL-13 as well as a variety of other effec...
Source: Fight Aging! - February 18, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Quiz Yourself to Grow What You Know About Regeneration
Regeneration is the natural process of replacing or restoring cells that have been lost or damaged due to injury or disease. A few animals can regrow entire organs or other body parts, but most have limited abilities to regenerate.
Scientists
in the field of regenerative medicine study how some animals are able to
rebuild lost body parts. By better understanding these processes and learning
how to control them, researchers hope to develop new methods to treat injuries
and diseases in people.
Take this quiz to test what you know about regeneration and regenerative medicine. Then check out our Regeneration fact sheet a...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - January 29, 2020 Category: Research Authors: Chrissa Chverchko Tags: Genes Cellular Processes Regeneration Source Type: blogs
Fight Aging! Newsletter, January 27th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - January 26, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
PAR1 Inhibition Activates Remyelination
Myelin is the sheathing of nerves, essential to their function. Excessive loss produces disabling and ultimately fatal conditions such as multiple sclerosis, but we all lose myelin integrity to some degree as a consequence of the damage and dysfunction of degenerative aging. This most likely contributes to cognitive decline and other age-related issues. A number of different approaches have been identified to boost the operation of the normal maintainance processes that remyelinate nerves, such as FGF21 upregulation, or increasing the size of remyelinating cell populations. Here, researchers discover another possible trigg...
Source: Fight Aging! - January 20, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
How do I know if my work fits in the mission of NIGMS?
Ninety percent of the applications to our Maximizing Investigators’ Research Award for Early Stage Investigators (known as the ESI MIRA program) that were submitted in October are about to undergo peer review. The remaining 10% were administratively withdrawn, mostly because the research proposed fell outside the NIGMS mission. This is comparable to the proportion that was withdrawn over the past 3 years.
Withdrawn applications represent a lot of wasted time and effort on the part of affected PIs and are the source of considerable frustration. So what can you do to minimize the chance of this happening to your ES...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - January 15, 2020 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Research Administration Early Stage Investigator Funding Policies MIRA Preparing an Application Source Type: blogs
