Clancy ’ s Rustic – Caradrina kadenii
As the year rolls by, the number of new moth species a novice moth-er with 3-4 years experience is likely to see on any given night declines with the arrival of autumn. All the moths I saw in my first season were pretty much new-for-me (NFM), about 127 species. In 2019, lighting up for a longer period, I recorded 125 NFM. 2020 wasn’t a great year not many moths at all after an unseasonably warm and sunny pre-Spring and I recorded just 30 NFM. Similarly, 37 NFM in 2021. However, despite odd weather again in 2022, I’ve recorded 49 NFM in the garden and a dozen with the LepiLED in the New Forest. Among those NFM s...
Source: David Bradley Sciencebase - Songs, Snaps, Science - September 15, 2022 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs

Allostatic Load Correlates with Risk of Age-Related Hearing Loss
Measures of aging tend to correlate with one another in any given study population. If someone is more affected by aging, then all of his or her physiology tends to be more functionally impacted. Thus it isn't always clear as to what can be learned from epidemiology of the sort noted here. One has to look closely at the details. Nonetheless, researchers here show that allostatic load over the course of aging correlates with the risk of suffering hearing loss. Allostatic load is a measure of stress and divergence from optimal function in the systems of the body, more or less, as determined by a range of biomarkers relating ...
Source: Fight Aging! - September 14, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Viral Infection as a Contributor to the Burden of Cellular Senescence
This open access paper discusses the evidence for viral infections to increase the burden of cellular senescence, specifically in the context of atherosclerosis and immunosenescence in aging. Viral infection is thought to contribute to both issues, and from what is known of the role of increased numbers of senescent cells in aging, it is possible that increased senescent cells numbers is a significant mechanism. Certainly, we should hope to see researchers establish that a great deal of degenerative aging, accelerated by viral infection or otherwise, can be blamed on the unwanted activities of lingering senescent cells. Th...
Source: Fight Aging! - September 13, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Reporting on a Study of One with Khavinson Peptides and Melatonin for Thymic Regrowth
Conclusion Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life. Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 12, 2022 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs

Undisclosed Conflicts of Interest by Physicians Creating the CDC Opioid Prescribing Guidelines: Bad Faith or Incompetence?
We described above how changes in opioid policy aimed at reducing Washington State’s Medicaid and Workers Compensation costs contributed to an increase in methadone deaths between 2003 and late 2014 (23-25). Focusing on similar cost reductions, the Centers for Medicar e and Medicaid Services (CMS) proposed rules for 2019 including several directives intended to reduce " Opioid Overutilization, ” including adoption of the “90 morphine milligram equivalent (MME) threshold cited by the 2016 CDC Opioid Guideline (147, 148). Simply put, reduced prescribing reduces costs for prescribed medications.Chou received research fu...
Source: Pallimed: A Hospice and Palliative Medicine Blog - September 12, 2022 Category: Palliative Care Tags: health policy judy kollas opioids research schechtman Source Type: blogs

Fight Aging! Newsletter, September 12th 2022
Discussion of Present Drug Development to Target Senescent Cells Targeting Senescent Cells to Better Address Cancer and Consequences of Cancer Therapy Calorie Restriction Suppresses Generation of Immune Cells via Changes to the Gut Microbiome Arguing for an Expansion of the Hallmarks of Aging https://www.fightaging.org/archives/2022/09/arguing-for-an-expansion-of-the-hallmarks-of-aging/ The hallmarks of aging form a catalog of largely better studied changes in cells and tissues considered relevant, and possibly more important, in the onset and development of age-related degeneration and disease. Thi...
Source: Fight Aging! - September 11, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

“Beyond Nicotine”: Tobacco Joins Hands With Pharma.
BY MIKE MAGEE Connecticut attorney general, William Tong, took a turn in the spotlight this week, representing 33 states and Puerto Rico in announcing that vaping original, Juul, had agreed to pay penalties of $438.5 million to settle lawsuits against the company. Juul in essence acknowledged that the company’s marketers had targeted young students, used social media to attract underage teens, and had given them free samples. With 45% of the company’s Twitter followers between ages 13 and 17, and an age verification methodology authorities label as “porous”, they were happy to get the nation’s attorney gene...
Source: The Health Care Blog - September 8, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Pharmaceuticals The Business of Health Care Mike Magee tobacco Source Type: blogs

Lesser Physical Function in Old Age Correlates with a Greater Cardiovascular Disease Risk
Better fitness in later life reduces mortality, and the study results here are just one of many examples that demonstrate this correlation, though specifically for cardiovascular disease in this case. While only correlations can be determined from most human data, animal studies make it quite clear that better fitness causes a reduced later life mortality. Maintaining better physical fitness is a good idea for many reasons, and it seems clear that health and longevity will benefit from doing so. The Atherosclerosis Risk in Communities (ARIC) study, an ongoing community-based cohort enrolled 15,792 participants, ag...
Source: Fight Aging! - September 8, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Convolvulus second coming
Usually, one relies on Attenborough and his marvellous army of photographers and researchers to bring the dramatic natural world closer to home. At a push Spring Watch and its ilk can give you a slightly less educational fix with their low-level narrative and low-level cameras. But, nature impinges on even the most urbane of urban gardens at times. Indeed, we see various butterflies in the garden on warm and sunny summer days – Comma, Painted Lady, Red Admiral, Peacock, Whites (Large and Small), Holly Blue, very occasionally Common Blue and Small Copper, even (once) Marbled White. Hummingbird Hawk-moths turn up duri...
Source: David Bradley Sciencebase - Songs, Snaps, Science - September 1, 2022 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs

The Legal and Scientific Infirmities of Legislating Nicotine Reduction
Barbara Pfeffer Billauer (Institute of World Politics), The Legal and Scientific Infirmities of Legislating Nicotine Reduction, Genetic Literacy Project (2022): Biden ’s proposal to reduce nicotine in cigarettes to “minimally or non-addictive” levels is devoid of both a scientific and legal... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 28, 2022 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Convolvulus Hawk-moth in Cambridge
The Convolvulus Hawk-moth, named for its larval food plant convolvulus (bindweed) and its hawk-like appearance, is a rather rare visitor to the UK from mainland Europe. Convolvulus Hawk-moth, Agrius convolvuli The books usually say it migrates rarely and will be seen only in the South West of England if it does, but it has appeared elsewhere, often carried in on the same weather as other migrants, such as the Hummingbird Hawk-moth. The Convolvulus Hawk-moth likes to nectar on tobacco plants and ginger lilies among other flowers and I have been growing the former in our back garden since I started mothing in the hope of se...
Source: David Bradley Sciencebase - Songs, Snaps, Science - August 27, 2022 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs

The Tobacco Endgame Avengers: Strategies for a Smokefree Future in Australia
Matthew Rimmer (Queensland University of Technology ), The Tobacco Endgame Avengers: Strategies for a Smokefree Future in Australia in Australian Pub. Health L.: Contemporary Issues and Challenges (Belinda Bennett& Ian Freckelton, eds., Forthcoming). This chapter explores contemporary issues and... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 26, 2022 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Educating Physicians About Firearm Safety and Injury Prevention
On this episode of the Academic Medicine Podcast, guests Katherine Hoops, MD, MPH, Andra Blomkalns, MD, MBA, and Allison Augustus-Wallace, PhD, MS, MNS, join host Toni Gallo to talk about firearm safety and injury prevention education. They discuss the role of physicians in engaging patients and communities in firearm injury risk reduction, the current state of firearm injury prevention education, and where the academic medicine community needs to go from here. This episode is now available through Apple Podcasts, Spotify, and anywhere else podcasts are available. A transcript is below. Read the articles d...
Source: Academic Medicine Blog - August 22, 2022 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Academic Medicine podcast firearm injury prevention firearm safety medical education Source Type: blogs

Reducing the Negative Effects of Smoking in Queensland: A Submission to the Queensland Government
Matthew Rimmer (Queensland University of Technology), Reducing the Negative Effects of Smoking in Queensland: A Submission to the Queensland Government, SSRN (2022): This submission calls upon the Queensland Government to raise its ambition in respect of tobacco control measures in... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 21, 2022 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

How not go get cancer
The Global Burden of Disease project is a decades long international collaboration, based at the Institute for Health Metrics and Evaluation at the University of Washington, but involving researchers around the world. It was originally funded by the World Bank, and now receives its principal support from the Bill and Melinda Gates Foundation. GBD (not to be confused with golden brown and delicious) essentially tries to quantify the prevalence of diseases, and injuries around the world; the prevalence of associated disability; causes of death; and risk factors. They use a lot of complicated methods. If you ' re really ...
Source: Stayin' Alive - August 19, 2022 Category: American Health Source Type: blogs