Thoughts on Air Pollution and Accelerated Aging
A number of large epidemiological studies demonstrate that particulate air pollution correlates with mortality and incidence of age-related disease, likely via mechanisms involving increased inflammation resulting from the interaction of particulates with lung tissue. While socioeconomic status interacts with both exposure to air pollution and life expectancy, it is nonetheless possible to disentangle these effects in some population studies. While the long-term trend is towards reduced air pollution, it seems likely that chronic inflammation will be controlled and its effects on tissues reversed via novel therapeutics on ...
Source: Fight Aging! - December 13, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Collagen, wrinkles, and ageing skin
Collagen is a protein that plays a crucial role in maintaining the structure, firmness, and elasticity of the skin. As we age, several changes occur in the collagen of our skin, contributing to the visible signs of ageing, such as the appearance of wrinkles.
Here are some key aspects of how collagen changes with age:
Decreased Production: The synthesis of collagen decreases with age, leading to a reduction in the overall amount of collagen in the skin. This reduced production is influenced by both genetic and environmental factors, such as sun exposure and lifestyle choices, like smoking and alcohol consumption. a balanced...
Source: David Bradley Sciencebase - Songs, Snaps, Science - December 12, 2023 Category: Science Authors: David Bradley Tags: Health and Medicine Source Type: blogs
5 Simple Habits and Routines to Keep You Away from Depression and Stress
One of the major problems facing today’s generation is depression. Excessive workload, changing lifestyle, loneliness, and financial pressure all lead to stress which results in depression. You feel unhappy, non-productive and withdrawn when you are depressed.
Many experts believe that establishing routines filled with healthy habits is a great way to move more efficiently through your day while expending less mental energy and even willpower in the process. Following simple routines like exercising, eating the right food, taking energy supplements, meditating, and getting sufficient sleep can help to manage str...
Source: PickTheBrain | Motivation and Self Improvement - December 7, 2023 Category: Consumer Health News Authors: jaya Tags: career confidence depression featured happiness health and fitness meditation motivation productivity tips self-improvement habits routines stress Source Type: blogs
Lessons from historical drug prohibitions
New Zealand just rescinded its ban on tobacco smoking at the same time that Donald Trump just suggested the death penalty could cure the drug problem. What did New Zealand learn? And how has drug prohibition worked out in the past? In 1511, the governor of Mecca, Khair Beg, had a serious problem. A powerful
Read more…
Lessons from historical drug prohibitions originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 1, 2023 Category: General Medicine Authors: L. Joseph Parker, MD Tags: Conditions Public Health & Policy Source Type: blogs
Why is the National Academies Appointing Alcohol-Industry Funded Researchers to Serve on Panel to Review the Health Effects of Alcohol?
In conclusion, there is no doubt that Dr. Mukamal should be removed from the National Academies panel in order to preserve the integrity of both the panel and of the National Academies itself.Although Dr. Rimm was not involved in the solicitation of funding, he didserve as a principal investigator of the MACH trial. Thus, he has been funded by the alcohol industry and this conflict of interest should disqualify him from participating in, much less chairing the panel. Dr. Rimmshould be removed from the National Academies panel in order to
preserve the integrity of both the panel and of the National Academies
itself.T...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - November 30, 2023 Category: Addiction Source Type: blogs
Like a flame to a moth – a song
Having collaborated with two of my very good, musical friends this month on two distinct songs, I assumed that would be the end of my musical inspiration, at least until 2024. But, then I was on Threads, and happened upon the account of singer-songwriter janapochop.
Cut to the chase, here’s my new song – Like a flame to a moth. It’s NOT about moths…
Genre Fluid by Dave Bradley
In the spirit of finding new music, I checked out her Spotify and there are some wondrous songs to be heard. In particular one called Pretty Please. Jana describes this, her latest song, as having been “produced by me in...
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 29, 2023 Category: Science Authors: David Bradley Tags: Music Source Type: blogs
AI ’ s Unforeseen Medical Discoveries: The Curious Case Of Unusual Associations
Artificial intelligence can do a plethora of astonishing things, which has been discussed thoroughly in the past year. We train models to assist medical work, from administration to image analysis, from triage to mental health support. And every now and then AI has curious medical discoveries, detecting things that – to the best of our human knowledge – should not be detectable from the input data. Like knowing the race of the patient from chest X-rays alone. These unusual associations present brand-new challenges to medical professionals.
In these cases, the medical detective work has a new aim: to understa...
Source: The Medical Futurist - November 28, 2023 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Artificial Intelligence in Medicine digital health Healthcare technology AI Source Type: blogs
How Patient Activation Made It Possible to Thrive with Kidney Disease
By DAVE WHITE
It had been 10 years since I’d seen a doctor when I arrived at the Emergency Room at George Washington University Hospital in October 2009. I was able to climb the first flight of stairs, but after I froze on the second, they brought me in on a wheelchair.
That was the first time I heard the dreaded words, “Your kidneys aren’t working.” I was put on dialysis immediately, and my life transformed into a series of tests and procedures. But even after three weeks at the hospital, it didn’t sink in that there was no cure.
I checked most risk factors for kidney disease: I ate the wrong foods, smo...
Source: The Health Care Blog - November 27, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy chronic kidney disease Dave White Patient Activation Measure Patient Activism patient advocacy Source Type: blogs
Fight Aging! Newsletter, November 20th 2023
In this study, we attempted to further explain the role, exact mechanism and target of ICA in treating AD from the ferroptosis perspective. We found that ICA could improve the neurobehavioral, memory, and motor abilities of AD mice. It could lower the ferroptosis level and enhance the resistance to oxidative stress. After inhibition of MDM2, ICA could no longer improve the cognitive ability of AD mice, nor could it further inhibit ferroptosis. Network pharmacological analysis revealed that MDM2 might be the target of ICA action.
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Particulate Air Pollution and Its Effects on the Mechan...
Source: Fight Aging! - November 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Zealous for Wellness: How to Replace Hype with Data
This article begins a series that looks at useful measures of health and how the companies that promote wellness programs demonstrate their success. We’ll see measurements of objective outcomes, patient-reported outcomes, and what payers look for when they can’t get direct evidence of improvements in wellness.
You’ll note, as we survey the wellness solutions and measurements used, that the leading organizations in this space are payers, not clinicians. I’m sure that doctors and nurse practitioners truly care for the overall happiness and wellbeing of their patients. But the institutions aren’t...
Source: EMR and HIPAA - November 14, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System LTPAC Telemedicine and Remote Monitoring ACOs Avanade Christiana Voelker Cli Source Type: blogs
Lifestyle Choices Do Slow Aging, Just Not as Much as We'd Like
In recent years, a number of epidemiological studies have demonstrated that people with healthier lifestyles tend to live longer, at least within the bounds of later life from 60 to 100. That in turn is reflected by a lesser burden of various forms of cell and tissue damage, such as the accumulation of senescent cells. This isn't a controversial statement, though there is room enough to argue for an eternity over just how large the effect of any specific choice might be, how that effect size varies between populations, how different choices combine, and so forth. Then on top of all of this, the question of what happens and...
Source: Fight Aging! - November 13, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, October 30th 2023
In conclusion, reported adherence to a healthy lifestyle is associated with reduced risk of all-cause and cause-specific mortality. Adherence to all four lifestyle factors resulted in the strongest protection.
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Source: Fight Aging! - October 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Sizable Mortality Risk Differences for Healthy versus Unhealthy Lifestyles in Later Life
In conclusion, reported adherence to a healthy lifestyle is associated with reduced risk of all-cause and cause-specific mortality. Adherence to all four lifestyle factors resulted in the strongest protection.
Link: https://doi.org/10.1186/s12877-023-04247-9 (Source: Fight Aging!)
Source: Fight Aging! - October 27, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Higher Serum Klotho Correlates with Lower Systemic Inflammation
The objective of this research is to determine the linkage between soluble Klotho (S-Klotho) level and systemic immune-inflammation index (SII).
Eligible participants with complete information of S-Klotho level and SII were selected from the National Health and Nutrition Examination Surveys (NHANES). Subsequently, weighted multivariate linear regression and subgroup analysis were carried out to evaluate the association. Totally, 11,108 adults with complete data on S-Klotho level, SII and other important covariates were included in final analysis. Multivariate liner regression revealed that high level of S-Klotho wa...
Source: Fight Aging! - October 26, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
