All data suggest unstable angina, but the angiogram is normal. Ken Grauer on stress testing.
A 50-something woman who has a gastric ulcer was experiencing epigastric pain for which she decided to come to the ED. Then, approxiately one hour prior to arrival, she experienced some chest discomfort which was sharp, central, 10/10, with SOB, diaphoresis, dizziness, and nausea. Since that time it has been intermittent. She called 911 and still had pain when the medics arrived, but it resolved with sublingual NTG x 2. On arrival she was chest pain free, but still had the epigastric pain.Prehospital vitals:We could not find the prehospital EKG.Here is the first ED ECG, recorded while asym...
Source: Dr. Smith's ECG Blog - July 2, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs
Lifestyle Medicine Could Be The Key To Digital Health Adoption
I’ve been wearing several generations and types of smartwatches for a couple of years and I only remove my watch when I shower. I use it to track my sleep and its smart alarm wakes me up at the optimal time every morning. With the pocketable Kardia, I regularly check my ECG at home to detect any anomalies. For an in-depth analysis of what my genetic makeup predisposes me to, I had my whole genome sequenced. And I bring relevant data to my general practitioner during my checkups so that we can decide on preventive measures. In short, I’m trying to live like the patient of the future, using lifestyle medicine to prev...
Source: The Medical Futurist - June 29, 2022 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Lifestyle medicine E-Patients Health Sensors & Trackers Healthcare Design Medical Education Personalized Medicine sleep stress food scanner sleep apnea Apple Watch Dr. Vernes Baylor ACLM Source Type: blogs
Fight Aging! Newsletter, June 27th 2022
In conclusion, this study confirms that innate immune training can be induced in aging healthy individuals as well as critically ill sepsis patients. We found that innate immune training can be induced regardless of age and there was no substantive difference in the immune trained phenotype as a function of age. We employed β-glucan as our immune training stimulus. The ability of glucan to induce the trained phenotype suggests that it may be possible to pharmacologically induce the immune trained phenotype in aging human immunocytes.
Sitting Time Correlates with Mortality Risk
https://www.fightaging.org/archi...
Source: Fight Aging! - June 26, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Voting Republican is bad for your health
Literally. A study byWarraich HJ, Kumar P, Nasir K, Joynt Maddox KE, and Wadhera RK in BMJfinds this: There has actually been lots of previous research on this general question. As the authors note, " Previous studies have shown that counties that elect Republican candidates tend to experience worse health outcomes, such as fewer gains in life expectancy and increased rates of opioid prescription.56789, " so this is just further confirmation. As they summarize their fndings, " the mortality gap between white residents in Democratic versus Republican counties increased fourfold. Rural Republican count...
Source: Stayin' Alive - June 24, 2022 Category: American Health Source Type: blogs
The weed with roots in hell
When I was a youth -- high school, college, and beyond -- everybody smoked pot. By everybody I mean pretty much all my friends and people who went to the same parties and belonged to the same political organizations (I was an activist) and roommates and girlfriends and casual acquaintances. It was just completely normal. It was illegal, but that didn ' t really apply to white people with college degrees. That just wasn ' t something we had to worry about, the cops weren ' t interested in us.Anyway, I really didn ' t see much, if any harm in it. All of the people I knew were perfectly functional, they did well in school the...
Source: Stayin' Alive - June 23, 2022 Category: American Health Source Type: blogs
Psychological Stress Accelerates Immune Aging via Lifestyle Choices
In this study, after statistically controlling for poor diet and low exercise, the connection between stress and accelerated immune aging wasn't as strong. What this means is people who experience more stress tend to have poorer diet and exercise habits, partly explaining why they have more accelerated immune aging."
Link: https://news.usc.edu/200213/stress-aging-immune-system/ (Source: Fight Aging!)
Source: Fight Aging! - June 21, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Mirage of Health
My personal update is that I ' m recovering day by day, but it ' s taking a while. I get a little stronger, a little more stamina each day and I expect to get back to my previous full strength in time to put in a solid week of work starting Monday. Meanwhile a little down time isn ' t the worse thing that could have happened.I ' ve gotten some very odd comments which show that some people harbor very basic misunderstandings about heath, illness and medicine. As I have noted here many times, medical intervention was largely ineffective until the 20th Century. It has grown more effective over the past 100+ years, but you nee...
Source: Stayin' Alive - June 17, 2022 Category: American Health Source Type: blogs
Nocturnal hypertension : Something Important is being cooked in the hypertensive world !
Some physics: Why is blood under pressure?
In perfect vascular climatic conditions, the human circulatory system is comparable to a smooth flowing river irrigating 100 trillion cells, traversing many kilometers of the capillary network, to the far away tissue bed. One major difference in the river analogy is, that in human biology, the entire blood has to return back to the heart in about 30 seconds. (The fact that the venous system does this in style with near-zero pressure head is the greatest wonder in circulatory physiology)
The force per unit area, that drives the blood is the blood pressure. It is expressed...
Source: Dr.S.Venkatesan MD - June 12, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Hypertension systemic hypertension acc aha esc hypertension guidelines dippers non dippers melatonin for nocturnal hypertension night time bp reverse dipper Source Type: blogs
Fight Aging! Newsletter, June 13th 2022
In conclusion, long-term cumulative BP was associated with subsequent cognitive decline, dementia risk, and all-cause mortality in cognitively healthy adults aged ≥50 years. Efforts are required to control long-term systolic BP and pulse pressure and to maintain adequate diastolic BP.
Longer-Lived Mammals Tend to Have Lower Expression of Inflammation-Related Genes
https://www.fightaging.org/archives/2022/06/longer-lived-mammals-tend-to-have-lower-expression-of-inflammation-related-genes/
Researchers here make a few interesting observations on gene expression data from a range of mammalian species with...
Source: Fight Aging! - June 12, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Metabolomics in the Context of Arterial Stiffness
A range of processes are involved in age-related stiffening of blood vessel walls. Cross-linking in the extracellular matrix leads to a loss of elasticity, as does disruption of elastin structures. In addition, inflammation and other issues cause dysfunction in the vascular smooth muscle cells responsible for contraction and dilation. Stiffness leads to hypertension, which in turn causes structural damage to delicate tissues throughout the body. Thus there is a strong incentive to better understand why stiffening occurs, and identify which of the various processes are most important and most amenable to interventions that ...
Source: Fight Aging! - June 10, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
June 09, 2022 Edition-----The Russian war on Ukraine is now well over 100 days old. The destruction and deaths are just awful and the world is being seriously re-shaped. Where this ends is unknowable but unlikely to be good.In the US we are seeing almost daily mass shootings and no-one seems to know what to do. Just pathetic.In the UK the hangover is slowly lifting after the 4 day royal celebration.In OZ we are having an energy crisis which we hope we will find solutions for soon!-----Major Issues.------https://www.theaustralian.com.au/business/economics/australias-labor-government-faces-a-whole-new-economic-ball-game/news...
Source: Australian Health Information Technology - June 9, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
The Khan review: making smoking obsolete - independent review into smokefree 2030 policies
Office for Health Improvement and Disparities -This independent review into the government ’s current tobacco control policies, led by Dr Javed Khan OBE, looks into whether government will achieve its ambition to make England smokefree by 2030. It finds that although good long-term progress has been made in reducing smoking rates to their lowest ever level, almost six million people sti ll smoke in England and smoking is still one of the largest causes of health disparities.ReviewOffice for Health Improvement and Disparities - publications (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - June 9, 2022 Category: UK Health Authors: The King ' s Fund Library Tags: Public health and health inequalities Source Type: blogs
The immune system
It occurs to me that right now, a great deal of trouble results from public misunderstanding of the immune system. It would actually be impossible for most of the public to understand very much about the immune system because it is extremely complicated. It depends on elaborate correlation of literally dozens of different kinds of cells, along with complicated features of all other human cells and of pathogens. Understanding how all of this works further depends on fairly deep understanding of basic biology, which believe me very few people have.Into this immense gulf of ignorance wade opportunistic charlatans who want to ...
Source: Stayin' Alive - June 2, 2022 Category: American Health Source Type: blogs
Fight Aging! Newsletter, May 30th 2022
In conclusion, fisetin supplementation may be a novel strategy to target excess cellular senescence and thereby reduce mitochondrial ROS to improve NO-mediated endothelial function with aging.
Exercise Upregulates BDNF Expression to Promote Dopamine Release and Brain Function
https://www.fightaging.org/archives/2022/05/exercise-upregulates-bdnf-expression-to-promote-dopamine-release-and-brain-function/
Researchers have in the past shown that exercise results in greater amounts of BDNF, which in turn promotes neurogenesis. Here, this line of research is extended to show that exercise results in an increa...
Source: Fight Aging! - May 29, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Does a Single Troponin below the 99th percentile URL Rule out Acute MI if the Chest pain is very prolonged?
A 66 y.o. male who presented for chest pain that started this AM when he woke up, and has persisted throughout the day prompting him to call 911. He says the pain is dull in nature and located across the chest, does not radiate, that it isworse with exhalation. He denies worsening with activity or positioning. He endorses SOB and requested to sit up. He says this has not happened to him before. He endorses cough productive of yellow sputum. He denies any edema. Denies history of venous thromboembolism. He endorses a 50 pack year history of smoking. He denies recent illness or recent s...
Source: Dr. Smith's ECG Blog - May 26, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs
