Lifestyle Produces a Much Greater Contribution to Human Life Expectancy than a Genetic Risk Score
Since the advent of very large databases of combined human genetic and epidemiological information, the evidence has increasingly leaned to support only a modest effect of genetic variation on human life span variation. Setting aside small populations with rare mutations, lifestyle has a much greater effect on life expectancy than one's genes. Even cases of familial longevity might largely result from transmission of culture, and thus lifestyle choices, rather than transmission of genetic variants.
Today's open access paper reports on data in which both genetic risk and lifestyle risk can be assessed. It is worth no...
Source: Fight Aging! - October 17, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Aspects of Social Determinants of Health: Defining and Sharing
This article delves deeper into various aspects of data handling, and who is working in these fields.
Defining SDoH
Lyd Paull-Flores, senior director, healthcare at GCOM, summarizes the social determinants of health in an article:
Economic stability
Economic access and quality
Social community and context
Healthcare access and quality
Neighborhood and built environment
A few different organizations have undertaken to categorize SDoH. The most comprehensive initiative, cited by several of my interviewees, is the Gravity project. Dr. Marc Rabner, chief medical officer of the nonprofit CRISP Shared Services (CSS), is on t...
Source: EMR and HIPAA - October 17, 2023 Category: Information Technology Authors: Andy Oram Tags: Analytics/Big Data C-Suite Leadership Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Regulations Care Management Clinical Architecture CRISP GCOM Gender Harmony Gravity Project HDUs Source Type: blogs
Out of Control Health Costs or a Broken Society
Flawed Accounting for the US Health Spending Problem
By Jeff Goldsmith
Source: OECD, Our World in Data
Late last year, I saw this chart which made my heart sink. It compared US life expectancy to its health spending since 1970 vs. other countries. As you can see, the US began peeling off from the rest of the civilized world in the mid-1980’s. Then US life expectancy began falling around 2015, even as health spending continued to rise. We lost two more full years of life expectancy to COVID. By the end of 2022, the US had given up 26 years-worth of progress in life expectancy gains. Adding four more ...
Source: The Health Care Blog - October 9, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy COVID Drug Overdoses gun violence Hospitals Jeff Goldsmith Maternal mortality Mental Health Obesity Poverty Regional Economy Society Source Type: blogs
Out of Control Health Costs or a Broken Society
Flawed Accounting for the US Health Spending Problem
By Jeff Goldsmith
Source: OECD, Our World in Data
Late last year, I saw this chart which made my heart sink. It compared US life expectancy to its health spending since 1970 vs. other countries. As you can see, the US began peeling off from the rest of the civilized world in the mid-1980’s. Then US life expectancy began falling around 2015, even as health spending continued to rise. We lost two more full years of life expectancy to COVID. By the end of 2022, the US had given up 26 years-worth of progress in life expecta...
Source: The Health Care Blog - October 9, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy COVID Drug Overdoses gun violence Hospitals Jeff Goldsmith Maternal mortality Mental Health Obesity Poverty Regional Economy Society Source Type: blogs
The Consequences of Health Mandates on Infant Health: Evidence from a Smoking-Ban Regulation
Daniel Da Mata (Getulio Vargas Foundation), Pedro Drugowick (Getulio Vargas Foundation), The Consequences of Health Mandates on Infant Health: Evidence from a Smoking-Ban Regulation (2023): Low- and middle-income countries, where more than four-fifths of the world ' s smokers live, are far... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - October 6, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
A man in his 40s with acute chest pain. What do you think?
Sent by anonymous, written by Pendell Meyers, reviewed by Smith and GrauerA man in his 40s presented to the ED with HTN, DM, and smoking history for evaluation of acute chest pain. He was eating lunch when he had sudden onset chest pressure, 9/10, radiating to his back, with sweating and numbness in both hands.Triage ECG:What do you think?It ' s a very " fun " ECG, with initial ectopic atrial tachycardia (negative P waves in inferior leads conducting 1:1 with the QRSs), followed by spontaneous resolution to sinus rhythm. In the available view of the sinus rhythm, we see normal variant STE which probably meets STEMI criteri...
Source: Dr. Smith's ECG Blog - September 29, 2023 Category: Cardiology Authors: Pendell Source Type: blogs
Very fast regular tachycardia: 2 ECGs from the same patient. What is going on?
This was written by Magnus Nossen, from Norway, with comments and additions by SmithA 50 something smoker with no previous medical hx contacted EMS due to acute onset chest pain. Upon EMS arrival the patient appeared acutely ill and complained of chest pain. An ECG was recorded immediately and is shown below. How do you interpret the ECG?ECG#1There is a regular tachycardia with a ventricular rate of about 180 bpm. Smith comment: When there is a regular wide complex tachycardia, first assess whether it is sinus or not. At a rate of 180, this is unlikely. The patient is unstable. Therefore, the first s...
Source: Dr. Smith's ECG Blog - September 27, 2023 Category: Cardiology Authors: Magnus Nossen Source Type: blogs
WHO Report: Tackling Hypertension Could Avert 76M Deaths Globally
Conclusion
Hypertension, often referred to as the “silent killer,” isn’t just a mere health term; it’s a pressing global challenge with vast implications.
As the World Health Organization’s report underscores, controlling high blood pressure is more than a matter of personal health. It’s about potentially averting millions of deaths worldwide by 2050.
It’s heartening to see countries like Canada and South Korea lead the charge with effective treatment programs, offering hope and a pathway for others to follow.
Yet, the contrasting statistics on sodium intake and the p...
Source: The EMT Spot - September 26, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
How Could Digital Technology Make An Impact On Primary Care?
I truly hope that very soon I do not have to make an appointment at the GP when I suspect signs of a disease, but my GP will send me a message that she spotted something irregular in my latest test results and my digital health data, so I’d better visit. Let me show you in detail how primary care should be carried out in the future!
Digital health should become an organic part of primary care in the future
I live a fairly healthy life. I use data to improve my lifestyle and to make better decisions by optimising my sleep pattern, my physical, my cognitive or my emotional abilities; and I had several genetic tests....
Source: The Medical Futurist - September 21, 2023 Category: Information Technology Authors: berci.mesko Tags: Digital Health Research Healthcare Innovation technology wearables GP primary care general practitioner Source Type: blogs
Chest discomfort and a dilated right ventricle. What's going on?
Written by Magnus Nossen MD, peer reviewed and edits by Smith, Meyers, GrauerA 60 something previously healthy female smoker sought medical attention after 2-3 days of intermittent chest discomfort. The chest discomfort was described as sharp. Episodes lasting 5-30 minutes. On the day of presentation she experienced another episode of chest discomfort accompanied by vomiting and throat pain. She was concerned about possible throat infection. She contacted her primary care physician. Due to the vague nature of her symptoms and the fact that she had chest discomfort and no clinical sign of throat infection she was referred f...
Source: Dr. Smith's ECG Blog - September 17, 2023 Category: Cardiology Authors: Magnus Nossen Source Type: blogs
What's new in midwifery - 13th September 2023 - Research
First, some original research that it might be useful to know about:Cervical Pessary for Prevention of Preterm Birth in Individuals With a Short Cervix: The TOPS Randomized Clinical Trial. Effectiveness and Costs of Molecular Screening and Treatment for Bacterial Vaginosis to Prevent Preterm Birth: The AuTop Randomized Clinical Trial. Group vs Individual Prenatal Care and Gestational Diabetes Outcomes: A Secondary Analysis of a Randomized Clinical Trial. Mid-trimester uterine artery Doppler for aspirin discontinuation in pregnancies at high risk for preterm pre-eclampsia: Post-hoc analysis ...
Source: Browsing - September 14, 2023 Category: Databases & Libraries Tags: midwifery Source Type: blogs
Ignoring High Blood Pressure After 60? Study Warns of a 42% Increase in Dementia Risk
Conclusion
The study brings to light startling data: untreated high blood pressure in people over 60 raises their risk of dementia by 42%.
It’s a finding that shouldn’t be ignored, considering the societal burden dementia poses.
Even when compared to individuals with treated hypertension, the risks remain elevated.
In essence, this compelling study highlights the critical need for treating high blood pressure in later life.
Doing so could significantly lower the risk of dementia, providing not just longer but also higher-quality lives for older adults.
Read next: High Blood Pressure In Your...
Source: The EMT Spot - September 14, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Reducing Cardiovascular Risk Factor Also Reduces Incidence of Neurodegenerative Disease
It is well known that the aging of the vasculature contributes to the aging of the brain. The brain requires a great deal of energy to operate, and the nutrients and oxygen needed for optimal brain metabolism are supplied in the bloodstream. With age, capillary density declines, the heart becomes weaker, and blood vessels are narrowed by the development of atherosclerotic lesions. All of this combines to reduce the delivery of nutrients to the brain, and its metabolism suffers as a result. Here, researchers present additional evidence to support this view of the impact of cardiovascular aging on brain aging.
Cardi...
Source: Fight Aging! - September 7, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men.
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Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis
https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/
Neurogenesis is the process by which new neurons are created by neural stem c...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
