Effects of Growth Factors and the MicroRNA-183 Family on Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells Towards Auditory Neuron-Like Cells.
Discussion: It can be concluded that miRNA is probably a good substitute for growth factors used in differentiating into ANs. Transdifferentiation of hBM-MSCs into ANs, which does not occur under normal conditions, may be thus facilitated by miRNAs, especially miRNA-182, or via a combination of miRNA and growth factors. PMID: 32982315 [PubMed] (Source: Stem Cells and Cloning: Advances and Applications)
Source: Stem Cells and Cloning: Advances and Applications - September 29, 2020 Category: Stem Cells Tags: Stem Cells Cloning Source Type: research

IJERPH, Vol. 17, Pages 7116: Sensory Processing, Functional Performance and Quality of Life in Unilateral Cerebral Palsy Children: A Cross-Sectional Study
Conclusions: UCP children have greater difficulty in sensory processing than TD children. Difficulties in proprioceptive processing contribute to poorer functional performance. Auditory, visual and tactile processing is associated with participation in the school environment and behavioral and social-emotional responses related to sensory processing are associated with the psychological well-being. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - September 27, 2020 Category: Environmental Health Authors: Jovellar-Isiegas Collados Ja én-Carrillo Roche-Seruendo Cuesta Garc ía Tags: Article Source Type: research

Sensory Modulation Disorder and its Neural Circuitry in Adults with ADHD: A Pilot Study
AbstractCompared to healthy controls (HCs), individuals with attention-deficit/hyperactivity disorder (ADHD) exhibit more symptoms of sensory processing disorder (SPD), which is associated with difficulties in educational and social activities. Most studies examining comorbid SPD-ADHD have been conducted with children and have not explored relations to brain volumes. In this pilot study, we assessed a subtype of SPD, sensory modulation disorder (SMD), and its relation to select brain volumes in adults with ADHD. We administered part of the Sensory Processing 3-Dimensions Scale (SP3D) to assess subtypes of SMD and collected...
Source: Brain Imaging and Behavior - August 7, 2020 Category: Neurology Source Type: research

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study
This study utilized three-dimensional arterial spin labeling (ASL) to identify HD-RLS-related perfusion patterns and potential relationships with disease severity. Twenty-six HD-RLS patients, 30 hemodialysis patients without restless legs syndrome (HD-nRLS) and 30 age-, sex-, and education-matched healthy controls were included in this study. One-way analysis of covariance and post hoc analyses were used to assess differences in cerebral blood flow (CBF) values, demographics and clinical data among the three groups. Pearson ’s correlation analysis was conducted between altered CBF values in the HD-RLS group and clinical ...
Source: Brain Imaging and Behavior - July 22, 2020 Category: Neurology Source Type: research

Sensory Processing Disorder: Implications for Primary Care Nurse Practitioners
Children are being seen more readily by nurse practitioners when behavioral concerns arise. Attention-deficit/hyperactivity disorder (ADHD) is a common and costly behavioral condition seen by nurse practitioners. ADHD may also affect children ’s sensory processing. Symptoms of ADHD often include those of sensory processing dysfunction. Sensory processing disorder, a condition in which sensory processing dysfunction impacts everyday functioning, is a condition commonly seen with ADHD. For children with ADHD and associated conditions, it is important for nurse practitioners to be versed in conservative management of these ...
Source: The Journal for Nurse Practitioners - June 14, 2020 Category: Nursing Authors: Jessica K. Wood Tags: Featured Article Source Type: research

Safe Place: Clinical Utility and Feasibility of a Multi-Disciplinary Intervention for Children with Sensory Processing Disorder and Complex Trauma – a Feasibility Study
AbstractIssues of feasibility, acceptability, satisfaction, safety, and fidelity were examined in a single case program review as an initial step to assessment of the clinical utility of the SAFE PLACE program, a unique multi-disciplinary intervention program for children with complex trauma and sensory processing disorder. The feasibility of conducting a pilot intervention study was also examined. A mixed methods, single-case, program review was conducted. The intervention was the 12-week SAFE PLACE program with pre and post-intervention baseline periods. Random intervention sessions were assessed for fidelity. Post-progr...
Source: Journal of Child and Adolescent Trauma - August 6, 2019 Category: Child Development Source Type: research

Associations between music and the sensory system: An integrative review for child therapy
Publication date: July 2019Source: The Arts in Psychotherapy, Volume 64Author(s): Vered Simhon, Cochavit Elefant, Hod OrkibiAbstractSensory processing disorder (SPD) is a disruption in the organization of sensory input that affects appropriate responses to the demands of the environment. The consequences of SPD in children may include a developmental lag as well as behavioral and emotional problems. Music therapy is particularly suitable for children with a sensory processing disorder because music and the sensory system are both linked to the nervous system. This suggests there is a need to better understand the relations...
Source: Arts in Psychotherapy - June 24, 2019 Category: Psychiatry & Psychology Source Type: research

Sensory Processing Difficulties Correlate With Disease Severity and Quality of Life Among Children With Migraine
Conclusion: The possible relationship between migraine and sensory processing disorder or difficulties stresses the need to screen for sensory processing difficulties among children with migraine and when found – refer to their impacts on children’s daily function and quality of life. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - May 23, 2019 Category: Neurology Source Type: research

Diffusion tensor tractography in children with sensory processing disorder: Potentials for devising machine learning classifiers
In this study, we determined the diffusion tensor imaging (DTI) microstructural and connectivity correlates of SPD, and apply machine learning algorithms for identification of children with SPD based on DTI/tractography metrics. A total of 44 children with SPD and 41 typically developing children (TDC) were prospectively recruited and scanned. In addition to fractional anisotropy (FA), mean diffusivity (MD), and radial diffusivity (RD), we applied probabilistic tractography to generate edge density (ED) and track density (TD) from DTI maps. For identification of children with SPD, accurate classification rates from a combi...
Source: NeuroImage: Clinical - April 24, 2019 Category: Radiology Source Type: research

Dynamic Compression Garments for Sensory Processing Disorder Treatment Using Integrated Active Materials
This study demonstrates the viability of SMA-based compression garments as an enabling technology for enhancing SPD (and other compression-based) treatment. (Source: Journal of Medical Devices, Transactions of the ASME)
Source: Journal of Medical Devices, Transactions of the ASME - March 6, 2019 Category: Medical Devices Source Type: research

Differences in Oculomotor Function between Children with Sensory Processing Disorder and Typical Development
CONCLUSIONS Because of significant differences in oculomotor function in children with SPD and the increasing number of children with neurosensory disorders, optometrists should consider NSUCO testing on all pediatric patients and particularly in children with SPD. (Source: Optometry and Vision Science)
Source: Optometry and Vision Science - March 1, 2019 Category: Opthalmology Tags: ORIGINAL INVESTIGATIONS Source Type: research

Creating a Sensory-Friendly Pediatric Emergency Department
This article describes the nurse-initiated PI process and the journey to create an evidence-based sensory-friendly pediatric emergency department. A model is presented so that other facilities can embark on their own initiative, and case studies are used to evaluate project outcomes.DiscussionIntegrating current evidence, staff suggestions, community input, and expert advice allowed us to find creative solutions to the unique sensory needs of children who visit our emergency department. Modifying both the patient-care environment and the patient-flow process to accommodate for the needs of children with ASD/SPD created a m...
Source: Journal of Emergency Nursing - January 21, 2019 Category: Nursing Source Type: research

Creating a Sensory-Friendly Pediatric Emergency Department
For children with autism spectrum disorder (ASD) and sensory-processing disorder (SPD), an unexpected visit to the emergency department can be an overwhelming experience that creates intensifying behaviors and an unsafe clinical interaction for the child, nurses, and providers. Although resources exist to help nurses work with this specialized group, there are limited examples of the challenges and opportunities of modifying an emergency department to be a place where nurses can provide sensory-informed care. (Source: Journal of Emergency Nursing: JEN)
Source: Journal of Emergency Nursing: JEN - January 21, 2019 Category: Nursing Authors: Elyssa B. Wood, Allyson Halverson, Gina Harrison, Amanda Rosenkranz Tags: Practice Improvement Source Type: research