TWiV 951: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses Influenza incidence and vaccine effectiveness during the southern hemisphere influenza season in Chile, Nirsevimab for prevention of RSV infection in healthy late-preterm and term infants, severe Monkeypox in hospitalized patients, reinfections with different SARS-CoV-2 Omicron subvariants, impact of community masking on COVID-19 in Bangladesh, unadjuvanted intranasal spike vaccine elicits protective … TWiV 951: Clinical update with Dr. Daniel Griffin Read More » (Source: virology blog)
Source: virology blog - November 5, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation influenza Long Covid marburg virus monkeypox monoclonal antibody Omicron pandemic poliovirus SARS-CoV-2 vaccine vaccine booster variant of concern Source Type: blogs

Micelle Technology Detects Airborne SARS-CoV-2
At the Pacific Northwest National Laboratory, researchers have developed micelle technology that can detect minute amounts of SARS-CoV-2 in the air. This new capability could provide invaluable monitoring systems to detect viral contamination in healthcare facilities and beyond. Micelles are somewhat similar to liposomes in that they are both like tiny lipid bubbles. In this instance, the researchers incorporated molecularly imprinted polymer molecules into the wall of the micelles. These molecularly imprinted molecules can bind to the viral spike protein. On viral binding, the polymer molecules cause the micelle to burst,...
Source: Medgadget - November 3, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Public Health covid COVID-19 SARS-CoV-2 Source Type: blogs

Antibodies Against SARS-CoV-2 Nucleocapsid Protein May Not Be Reliable Markers for Infection in Vaccinated People
by Gertrud U. Rey You are fully vaccinated against SARS-CoV-2 and have presumably never been infected with the virus. But how can you know for sure? One way to find out is by testing your blood for the presence of antibodies against the viral nucleocapsid protein, which can only be encountered during natural infection. This […] (Source: virology blog)
Source: virology blog - November 3, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey antibodies immunity natural infection nucleocapsid nucleocapsid protein SARS-CoV-2 spike glycoprotein sterilizing immunity vaccine-induced antibodies Source Type: blogs

Antibodies Against SARS-CoV-2 Nucleocapsid Protein May Not Be Reliable Markers for Infection in Vaccinated People
by Gertrud U. Rey You are fully vaccinated against SARS-CoV-2 and have presumably never been infected with the virus. But how can you know for sure? One way to find out is by testing your blood for the presence of antibodies against the viral nucleocapsid protein, which can only be encountered during natural infection. This … Antibodies Against SARS-CoV-2 Nucleocapsid Protein May Not Be Reliable Markers for Infection in Vaccinated People Read More » (Source: virology blog)
Source: virology blog - November 3, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey antibodies immunity natural infection nucleocapsid nucleocapsid protein SARS-CoV-2 spike glycoprotein sterilizing immunity vaccine-induced antibodies Source Type: blogs

TWiV 949: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses of JYNNEOS vaccine for prevention of Monkeypox, distinguishing SARS-CoV-2 persistence and reinfection, Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages, association between regular physical activity a...
Source: virology blog - October 29, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation influenza Long Covid marburg virus monkeypox monoclonal antibody Omicron pandemic poliovirus SARS-CoV-2 vaccine vaccine booster variant of concern Source Type: blogs

mRNA Therapy Prevents COVID Virus Entering Cells
Scientists at Oregon State University have developed a new treatment for COVID-19. The technology is based on mRNA, which has also been put to good use in COVID-19 vaccines. However, in this instance, the delivered mRNA encodes for human angiotensin-converting enzyme 2 (hACE2), which is the binding site for SARS-CoV-2 on airway cells. The lipid nanoparticle-encapsulated mRNA therapeutic is delivered to cells in the body, and then the cells begin to produce and release a free-floating form of hACE2 that acts as a decoy to soak up viral particles. Once the viral particles are bound to the decoys, they are no longer avail...
Source: Medgadget - October 25, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine Public Health covid COVID-19 OregonState SARS-CoV-2 Source Type: blogs

TWiV 948: Breathless with David Quammen
David Quammen returns to TWiV to discuss how he wrote his new book 'Breathless', a story about the science and the scientists behind the race to understand the pandemic coronavirus SARS-CoV-2. (Source: virology blog)
Source: virology blog - October 23, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology Breathless coronavirus COVID-19 david quammen genome sequence pandemic SARS-CoV-2 vaccine viral viruses Source Type: blogs

TWiV 947: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the prediction of upcoming global infection burden of influenza seasons after relaxation of public health and social measures during the COVID-19 pandemic, severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters, and how successful immunomodulators for treatment of COVID-19 have opened the pathway for comparative trials. (Source: virology blog)
Source: virology blog - October 22, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation influenza Long Covid marburg virus monkeypox monoclonal antibody Omicron pandemic poliovirus SARS-CoV-2 vaccine vaccine booster variant of concern Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
October 20, 2022 Edition-----In the US we have just had the usual mass-shootings last week! Hard to know why the population put up with it. On a larger scale the war is seemingly just getting worse and more lethal. While there is assassination there must be hope!In the UK all eyes are on just when the Truss implosion will actually happen.In OZ the biggest news has been the really Biblical floods in SE Australia, The Budget is also getting close!-----Major Issues.-----https://www.afr.com/policy/tax-and-super/average-tax-rate-to-hit-record-high-this-decade-with-or-without-stage-three-cuts-20221008-p5bo78Average tax rate to h...
Source: Australian Health Information Technology - October 20, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

TWiV 945: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses a healthcare-associated infection with Monkeypox virus, air and surface sampling for monkeypox virus in a UK hospital, misrepresentation and nonadherence regarding COVID19 public health measures, tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine, clinical, virologic, and immunologic evaluation of symptomatic rebound following Nirmatrelvir/Ritonavir treatment, early outpatient treatment with Eemdesivir in patients at high risk for severe COVID-19, Molnupiravir plus usual care versus usual care alone as early treatme...
Source: virology blog - October 15, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation influenza Long Covid marburg virus monkeypox monoclonal antibody Omicron pandemic poliovirus SARS-CoV-2 vaccine vaccine booster variant of concern Source Type: blogs

The college football fans that beat COVID and the experts that couldn ’t
BY ANISH KOKA The COVID pandemic was supposed to herald the end of the idea that a smaller government is a better government. The experts who desperately seek to be in charge of a sprawling bureaucratic state told us that it was only a powerful central authority that could do what was needed to safeguard individual liberties at a time when a highly contagious respiratory virus was spreading across the globe. New Zealand may have imposed draconian policies that did not even allow its own citizens to return, but scenes of cheering unmasked New Zealanders stood in sharp contrast to empty seats in American stadiums when ...
Source: The Health Care Blog - October 12, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: COVID-19 Health Policy College Football New Zealand Source Type: blogs