Salvia Officinalis Improves Glucose Uptake and Suppresses Ectopic Lipid Deposition in Obese Rats with Metabolic Syndrome
CONCLUSION: The findings imply that SAGEAE could be used as a new pharmaceutical formula in the treatment of obesity.PMID:37581324 | DOI:10.2174/1389201024666230811104740 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - August 15, 2023 Category: Biotechnology Authors: Diana A ALsherif Mohammed A Hussein Suzan S Abuelkasem Soha A Hassan Michael Wink Source Type: research

Salvia Officinalis Improves Glucose Uptake and Suppresses Ectopic Lipid Deposition in Obese Rats with Metabolic Syndrome
CONCLUSION: The findings imply that SAGEAE could be used as a new pharmaceutical formula in the treatment of obesity.PMID:37581324 | DOI:10.2174/1389201024666230811104740 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - August 15, 2023 Category: Biotechnology Authors: Diana A ALsherif Mohammed A Hussein Suzan S Abuelkasem Soha A Hassan Michael Wink Source Type: research

Molecules, Vol. 28, Pages 5749: Fortification of Fermented Camel Milk with Salvia officinalis L. or Mentha piperita Leaves Powder and Its Biological Effects on Diabetic Rats
tb Elmahallawy The incorporation of fermented camel milk with natural additives possesses numerous benefits for the treatment of various pathological and metabolic conditions. The present study investigated the impact of fortification of fermented camel milk with sage or mint leaves powder (1 and 1.5%, respectively) on glucose and insulin levels, lipid profile, and liver and kidney functions in alloxan-induced diabetic rats. The gross chemical composition of sage and peppermint leaves powder was studied. The chemical composition of sage and mint extracts was performed using liquid chromatography–electrosp...
Source: Molecules - July 29, 2023 Category: Chemistry Authors: Magdy Ramadan Shahein Mahmoud Ibrahim El-Sayed Enrique Raya- Álvarez Abdelmoneim Ahmed Elmeligy Mohamed A. Mohamady Hussein Murad A. Mubaraki Ahmad Agil Ehab Kotb Elmahallawy Tags: Article Source Type: research

Genkwanin: An emerging natural compound with multifaceted pharmacological effects
Biomed Pharmacother. 2023 Jul 21;165:115159. doi: 10.1016/j.biopha.2023.115159. Online ahead of print.ABSTRACTPlant bioactive molecules could play key preventive and therapeutic roles in chronological aging and the pathogenesis of many chronic diseases, often accompanied by increased oxidative stress and low-grade inflammation. Dietary antioxidants, including genkwanin, could decrease oxidative stress and the expression of pro-inflammatory cytokines or pathways. The present study is the first comprehensive review of genkwanin, a methoxyflavone found in several plant species. Indeed, natural sources, and pharmacokinetics of...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 23, 2023 Category: Drugs & Pharmacology Authors: Naoual El Menyiy Sara Aboulaghras Saad Bakrim Rania Moubachir Doaue Taha Asaad Khalid Ashraf N Abdalla Alanood S Algarni Andi Hermansyah Long Chiau Ming Marius Emil Rusu Abdelhakim Bouyahya Source Type: research

The Impact of < em > Origanum vulgare < /em > Supplementation on Human Asthenozoospermic Sperm Parameter Quality
ScientificWorldJournal. 2023 Jun 24;2023:8093795. doi: 10.1155/2023/8093795. eCollection 2023.ABSTRACTMale infertility is a complex multifactorial disease and a real health problem; 50% of infertile men have identifiable causes detectable by fundamental sperm analysis. Numerous research studies have shown the possibility of treating abnormal semen samples with some drugs before artificial insemination, yet evidence of the drug's effectiveness remains minimal. In our previous work, we tested the effectiveness of some essential oils, such as eucalyptus (Eucalyptus globulus Labill.), oregano (Origanum vulgare L.), and sage (S...
Source: The Scientific World Journal - July 13, 2023 Category: Science Authors: Ahlam Zarhouti Moudou M Mbaye Boutaina Addoum Noureddine Louanjli Bouchra El Khalfi Abdelaziz Soukri Source Type: research

Retraction Note: Anti-oxidant and hepatoprotective effects of Salvia officinalis essential oil against vanadium-induced oxidative stress and histological changes in the rat liver
Environ Sci Pollut Res Int. 2023 Jul 12. doi: 10.1007/s11356-023-28716-1. Online ahead of print.NO ABSTRACTPMID:37434061 | DOI:10.1007/s11356-023-28716-1 (Source: Environmental Science and Pollution Research International)
Source: Environmental Science and Pollution Research International - July 11, 2023 Category: Environmental Health Authors: Fatma Ghorbel Koubaa Mariem Cha âbane Mouna Turki Fatma Makni Ayadi Abdelfattah El Feki Source Type: research

Effect of Salvia officinalis aqueous infusion on copper sulfate-induced inflammatory response and oxidative stress imbalance in mice liver and kidney
. (Source: Drug and Chemical Toxicology)
Source: Drug and Chemical Toxicology - June 26, 2023 Category: Toxicology Authors: Houcine DabSaid Ben HamedAmel JeryAmel ChehidiLazhar Zourguia Laboratory of Biodiversity, Molecules, Applications, (LR22ES02) Higher Institute of Applied Biology of Medenine, University of Gabes, Medenine, Tunisiab Laboratory of Epidemiology and Veterinar Source Type: research

Forecasting of potential anti-inflammatory targets of some immunomodulatory plants and their constituents using in vitro, molecular docking and network pharmacology-based analysis
Sci Rep. 2023 Jun 12;13(1):9539. doi: 10.1038/s41598-023-36540-3.ABSTRACTMost synthetic immunomodulatory medications are extremely expensive, have many disadvantages and suffer from a lot of side effects. So that, introducing immunomodulatory reagents from natural sources will have great impact on drug discovery. Therefore, this study aimed to comprehend the mechanism of the immunomodulatory activity of some natural plants via network pharmacology together with molecular docking and in vitro testing. Apigenin, luteolin, diallyl trisulfide, silibinin and allicin had the highest percentage of C-T interactions while, AKT1, CA...
Source: Atherosclerosis - June 12, 2023 Category: Cardiology Authors: Asmaa Khairy Doaa A Ghareeb Ismail Celik Hala M Hammoda Hala H Zaatout Reham S Ibrahim Source Type: research

Salvia officinalis L. Methanolic Extract Reduces Lead and Nicotine-Induced Sperm Quality Degeneration in Male Rats
Chem Biodivers. 2023 May 26:e202300115. doi: 10.1002/cbdv.202300115. Online ahead of print.ABSTRACTThe current study is aimed at evaluating the potential health benefits of Salvia officinalis L. (sage) methanol extract on lead and nicotine hydrogen tartrate-induced sperm quality degeneration in male rats and also identifying some of the non-polar volatile bioactive compounds that might be attributed to the bioactivity of S. officinalis extract using gas chromatography-mass spectrometry (GC-MS). In the study, fifty-four mature male albino rats of about 220 - 250 g [were divided randomly and equally into 9 groups (n=6)]. Spe...
Source: Chemistry and Biodiversity - May 26, 2023 Category: Biochemistry Authors: Wael Ammar Aldaddou Abdullah S M Aljohani Idris Adewale Ahmed Naser A Al-Wabel Ibrahim M El-Ashmawy Source Type: research