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Microplastics affect soil-plant system: Implications for rhizosphere biology and fitness of sage (Salvia officinalis L.)
Environ Pollut. 2024 Feb 24:123656. doi: 10.1016/j.envpol.2024.123656. Online ahead of print.ABSTRACTA mesocosm experiment was set-up to investigate the effects of low-density polyethylene (LDPE) fragments deriving from plastic film on soil ecology, rhizosphere and plant (Salvia officinalis L.) fitness. The internal transcribed spacer (ITS) and 16S metagenomic analysis was adopted to evaluate taxonomic and functional shifts of both soil and rhizosphere under the influence of microplastics (MPs). Photosynthetic parameters and enzymes involved in oxidative stress were assessed to unveil the plant physiological state. MP frag...
Source: Environmental Pollution - February 26, 2024 Category: Environmental Health Authors: Maria Antonietta Ranauda Daniela Zuzolo Maria Maisto Maria Tartaglia Pierpaolo Scarano Antonello Prigioniero Rosaria Sciarrillo Carmine Guarino Source Type: research

Salvia officinalis L. exerts oncostatic effects in rodent and in vitro models of breast carcinoma
Conclusion: The dominant metabolites found in S. officinalis propylene glycol extract (SPGE) were representatives of phenolics, specifically rosmarinic, protocatechuic, and salicylic acids. Furthermore, the occurrence of triterpenoids ursolic and oleanolic acid was proved in SPGE. In a mouse model, a non-significant tumor volume decrease after S. officinalis treatment was associated with a significant reduction in the mitotic activity index of 4T1 tumors by 37.5% (SAL 0.1) and 31.5% (SAL 1) vs. controls (set as a blank group with not applied salvia in the diet). In addition, salvia at higher doses significantly decreased n...
Source: Frontiers in Pharmacology - February 23, 2024 Category: Drugs & Pharmacology Source Type: research

Molecules, Vol. 29, Pages 625: Extraction Optimization and Qualitative/Quantitative Determination of Bioactive Abietane-Type Diterpenes from Three Salvia Species (Common Sage, Greek Sage and Rosemary) by 1H-qNMR
The objective of this study was the optimization of the extraction process and the qualitative and quantitative determination of the bioactive metabolites: 12-O-methylcarnosic acid (12MCA), carnosic acid (CA), carnosol (CS), 7-O-methyl-epi-rosmanol (7MER) and rosmanol (RO) in infusions, decoctions, turbulent flow extracts, tinctures and oleolites from three Salvia species: Salvia officinalis L.(common sage, SO), Salvia fruticosa Mill.(Greek sage, SF) and Salvia rosmarinus Spenn (syn Rosmarinus officinalis L.) (rosemary, SR), using Quantitative Proton Nuclear Magnetic Resonance Spectroscopy (1H-qNMR). Regarding the aqueous ...
Source: Molecules - January 28, 2024 Category: Chemistry Authors: Panagiotis Kallimanis Prokopios Magiatis Angeliki Panagiotopoulou Kostas Ioannidis Ioanna Chinou Tags: Article Source Type: research

Immunity, rumen metagenomics, ruminal variables, and growth performance of calves fed milk with sage (Salvia officinalis) essential oil
AbstractThe study aimed to determine the effect of sage (Salvia officinalis) essential oil (EO) to the drinking milk until the weaning stage ofHolstein calves on the growth performance, body measurements, ruminal fermentation, rumen metagenomic profile, proinflammatory cytokines [interleukin-6 (IL-6), tumor necrosis factor (TNF- α), and IL-1β], immune globulins (IgG, IgM, and IgE), and acute phase proteins (serum amyloid-A, SAA). In the study, 24Holstein calves were divided into three groups as 0 μL (SAG0; control group), 100 μL (SAG100), or 200 μL (SAG200) of sage EO to the milk per calf per day. The addition of sage...
Source: Tropical Animal Health and Production - December 27, 2023 Category: Veterinary Research Source Type: research

Molecules, Vol. 29, Pages 94: The Different Phytochemical Profiles of Salvia officinalis Dietary Supplements Labelled for Menopause Symptoms
Baraldi Firenzuoli Phytochemical screening of four commercial products containing Salvia officinalis was carried out. Total phenolic content was estimated spectrophotometrically through the use of the Folin&ndash;Ciocalteau method, flavonoid content was measured through the use of aluminum chloride and 2,4-dinitrophenylhydrazine colorimetric assays, and isoflavones and &alpha;/&beta;-thujones were analyzed through the use of high-performance liquid chromatograph (HPLC) and the gas chromatographic method. The analyses revealed the absence of thujones and isoflavones (i.e., genistin, genistein...
Source: Molecules - December 22, 2023 Category: Chemistry Authors: Maggini Bertazza Gallo Mascherini Calvi Marra Michelucci Liberati Trassi Baraldi Firenzuoli Tags: Article Source Type: research

Effects of sage (Salvia officinalis) essential oil on growth, health and antioxidant capacity of common carp (Cyprinus carpio)
AbstractIn the study, effects ofS. officinalis essential oil on growth performance, health and antioxidant activity inC. carpio were investigated. The fish (13 ± 0.21 g) were fed with diet containing 1 and 3 ml kg− 1 of sage oil for 60 days. At the end of study, growth performance was not affected in fish fed with sage essential oil (p > 0.05). Superoxide dismutase (SOD) activity in hepatopancreas increased with addition of 1ml kg− 1 sage oil to the diet. However, Catalase (CAT) activity and malondialdehyde (MDA) values were not significantly altered in common carp. Total protein, albumin, glucose an...
Source: Veterinary Research Communications - November 28, 2023 Category: Veterinary Research Source Type: research

Molecules, Vol. 28, Pages 7762: Green Synthesis of Chitosan-Capped Gold Nanoparticles Using Salvia officinalis Extract: Biochemical Characterization and Antimicrobial and Cytotoxic Activities
This study evaluated the antioxidant and antimicrobial activities of human pathogenic multidrug-resistant (MDR) and multisensitive (MS) bacterial isolates using the agar diffusion method. Chi/BAuNPs showed inhibition of the MDR strains more effectively than BAuNPs alone as compared with a positive standard antibiotic. The cytotoxicity assay revealed that the human breast adenocarcinoma cancer cells (MCF7) were more sensitive toward the toxicity of 5-Fu + BAuNPs and 5-Fu + Chi/BAuNPs composites compared to non-malignant human fibroblast cells (HFs). The study shows that BAuNPs and Chi/BAuNPs, combined with 5-FU NPs, can eff...
Source: Molecules - November 24, 2023 Category: Chemistry Authors: Faisal Al-Sarraj Ibrahim Alotibi Majid Al-Zahrani Raed Albiheyri Mashail A. Alghamdi Nada M. Nass Sawsan Abd-Ellatif Raafat T. M. Makhlof Mohammad A. Alsaad Bayan H. Sajer Hazem S. Elshafie Tags: Article Source Type: research

Salvia officinalis flowers extract ameliorates liver and kidney injuries induced by simultaneous intoxication with ethanol/castor oil
In conclusion, SF-AE can potentially improve liver and kidney injuries associated with biochemical parameter deregulations, possibly by controlling oxidative stress and inflammation. (Source: Physiological Reports)
Source: Physiological Reports - November 14, 2023 Category: Physiology Authors: Saber Jedidi, Kais Rtibi, Houcine Selmi, Foued Aloui, Hichem Sebai Tags: ORIGINAL ARTICLE Source Type: research

Plants and mental disorders: the case of Catalan linguistic area
Discussion: The number of use reports analysed to treat mental disorders in CLA is 2,544 spread over 183 taxa belonging to 64 families, being the most cited the Malvaceae (29.36% of use reports), Lamiaceae (16.71%), Caprifoliaceae (7.94%), Rutaceae (7.47%) and Papaveraceae (6.01%). The most used taxa to treat or alleviate the mental disorders have been Tilia platyphyllos Scop. (24.53%), Valeriana officinalis L. (7.47%), Salvia officinalis L. (5.07%), Sambucus nigra L. (4.28%), and Ruta chalepensis L. (3.89%). The flowers or inflorescences (47.68%), followed by aerial part (23.49%), have been the most used plant parts, and ...
Source: Frontiers in Pharmacology - October 31, 2023 Category: Drugs & Pharmacology Source Type: research

Exogenous putrescine changes biochemical (antioxidant activity, polyphenol, flavonoid, and total phenol compounds) and essential oil constituents of Salvia officinalis L
Chem Biodivers. 2023 Sep 26:e202301043. doi: 10.1002/cbdv.202301043. Online ahead of print.ABSTRACTThis research is based on principal component analysis (PCA) and calculation of selection criteria (SC) to investigate the effect of foliar spraying of polyamine putrescine on essential oil yield, essential oil compounds, antioxidant activity, and biochemical compounds (polyphenol, flavonoid, and total phenol compounds) of Salvia officinalis. The treatments used included four levels of putrescine, Put (Control: 0, Put1: 500, Put2: 1000, and Put3: 1500 mg L- 1) with five replications. Based on our results, four factors had eig...
Source: Chemistry and Biodiversity - September 26, 2023 Category: Biochemistry Authors: Reza Zeynali Sharareh Najafian Mehdi Hosseinifarahi Source Type: research

Effect of Salvia officinalis scent on postmenopausal women ’s sexual function and satisfaction: a randomized controlled trial
Sexual function is one of the important aspects of quality of life which is often impaired after menopause. Given the side effects of hormone therapy on postmenopausal women, alternative treatments such as aro... (Source: BMC Women's Health)
Source: BMC Women's Health - August 23, 2023 Category: OBGYN Authors: Sousan Heydarpour, Foruzan Sharifipour and Fateme Heydarpour Tags: Research Source Type: research

Molecules, Vol. 28, Pages 6094: The Use of Ultrasound-Assisted Maceration for the Extraction of Carnosic Acid and Carnosol from Sage (Salvia officinalis L.) Directly into Fish Oil
yk The aim of the study was to examine the effect of ultrasonic maceration (U) on the extraction of carnosic acid (CA) and its derivative&mdash;carnosol (C)&mdash;directly from sage into fish oil, compared to homogenization-assisted maceration (H). It was shown that the ultrasonic maceration process (U) allowed for obtaining a macerate enriched in carnosic acid (CA) and carnosol (C), also containing rosmarinic acid (RA), total polyphenols, and plant pigments, and showing antioxidant properties (DPPH test). There was no unequivocal difference in the efficiency of extracting ingredients from sage into the...
Source: Molecules - August 16, 2023 Category: Chemistry Authors: Agnieszka M. Hrebie ń-Filisińska Grzegorz Tokarczyk Tags: Article Source Type: research