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Antimicrobial activity of essential oils against biofilms formed in dental acrylic resin: a systematic review of in vitro studies
In conclusion, the EOs of C. zeylanicum, C. citratus, C. nardus, and M. alternifolia showed antimicrobial activity to reduce biofilm on dental acrylic resin.PMID:38538551 | DOI:10.1080/08927014.2024.2332709 (Source: Biofouling)
Source: Biofouling - March 27, 2024 Category: Molecular Biology Authors: Jo ão Marcos Carvalho-Silva Ana Beatriz Vilela Teixeira Mariana Lima da Costa Valente Marcos Vinicius Wada Shimano Andr éa Cândido Dos Reis Source Type: research

Brain Mitochondria as a Therapeutic Target for Carnosic Acid
J Integr Neurosci. 2024 Mar 7;23(3):53. doi: 10.31083/j.jin2303053.ABSTRACTCarnosic acid (CA), a diterpene obtained mainly from Rosmarinus officinalis and Salvia officinalis, exerts antioxidant, anti-inflammatory, and anti-apoptotic effects in mammalian cells. At least in part, those benefits are associated with the ability that CA modulates mitochondrial physiology. CA attenuated bioenergetics collapse and redox impairments in the mitochondria obtained from brain cells exposed to several toxicants in both in vitro and in vivo experimental models. CA is a potent inducer of the major modulator of the redox biology in animal...
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Vittoria Infantino Ilaria Pappalardo Anna Santarsiero Swapnil Tripathi Gyanendra Singh Marcos Roberto de Oliveira Source Type: research

 Salvia officinalis L. exerts oncostatic effects in rodent and in vitro models of breast carcinoma
Conclusion: The dominant metabolites found in S. officinalis propylene glycol extract (SPGE) were representatives of phenolics, specifically rosmarinic, protocatechuic, and salicylic acids. Furthermore, the occurrence of triterpenoids ursolic and oleanolic acid was proved in SPGE. In a mouse model, a non-significant tumor volume decrease after S. officinalis treatment was associated with a significant reduction in the mitotic activity index of 4T1 tumors by 37.5% (SAL 0.1) and 31.5% (SAL 1) vs. controls (set as a blank group with not applied salvia in the diet). In addition, salvia at higher doses significantly decreased n...
Source: Cancer Control - March 11, 2024 Category: Cancer & Oncology Authors: Peter Kubatka Alena Mazurakova Lenka Koklesova Tomas Kuruc Marek Samec Karol Kajo Klaudia Kotorova Marian Adamkov Karel Smejkal Emil Svajdlenka Dana Dvorska Dusan Brany Eva Baranovicova Vladimira Sadlonova Jan Mojzis Martin Kello Source Type: research