Plants used during maternity, menstrual cycle and other women's health conditions among Brazilian cultures
Conclusion The survey raised important data about plants implemented in healing related to women's health conditions by Brazilian cultures and their practices. The compilation presented in this study enables the realization of further investigation regarding the development of herbal medicines and contributes to the incrementation of policies focused on these cultures. Further phytochemical, pharmacological and toxicological studies should be conducted, which will allow the discovery of pharmacological properties, bioactive constituents, and moreover, adequate posology, manner of use and adverse events. Graphical abstract...
Source: Journal of Ethnopharmacology - January 12, 2016 Category: Drugs & Pharmacology Source Type: research
Comparative evaluation of the antimicrobial activity of 19 essential oils.
This study demonstrated the noteworthy antimicrobial activity of two commercial EOs and points out the remarkable efficiency of T. vulgaris EOtun on all tested bacterial and fungal species, certainly associated with its high content in carvacrol (85 %). These three oils could thus represent promising candidates for applications in water and food protections.
PMID: 26566647 [PubMed - as supplied by publisher] (Source: Advances in Experimental Medicine and Biology)
Source: Advances in Experimental Medicine and Biology - November 21, 2015 Category: Research Tags: Adv Exp Med Biol Source Type: research
Molecules, Vol. 20, Pages 18907-18922: Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception
Ruta graveolens (rue) is a spontaneous plant in the Mediterranean area with a strong aroma and a very intense bitter taste, used in gastronomy and in folk medicine. From the leaves, stems and fruits of rue, we isolated rutin, rutamarin, three furanocoumarins, two quinolinic alkaloids, a dicoumarin and two long chain ketones. Bitter taste and chemesthetic properties have been evaluated by in vitro assays with twenty receptors of the TAS2R family and four TRP ion channels involved in gustation and nociception. Among the alkaloids, skimmianine was active as a specific agonist of T2R14, whereas kokusaginin did not activate any...
Source: Molecules - October 16, 2015 Category: Chemistry Authors: Giuseppe MancusoGigliola BorgonovoLeonardo ScaglioniAngela Bassoli Tags: Article Source Type: research
A novel coumarin derivative, 8-methoxy chromen-2-one alleviates collagen induced arthritis by down regulating nitric oxide, NFκB and proinflammatory cytokines.
Abstract
Ruta graveolens (Rue) is a well-known medicinal plant having anti-inflammatory and other healing properties. This contains many active phytochemicals such as coumarins which possess anti-inflammatory and anti-cancer activities. The present study was carried out to evaluate the therapeutic potential of a newly isolated coumarin derivative from rue plant, 8-methoxy-chromen-2-one (MCO) in the collagen induced arthritic (CIA) rat model. MCO showed inhibition of cytokines and NF-κB in LPS stimulated J774 cells which prompted its possible use in animal. In CIA, arthritic index and arthritic score reduc...
Source: International Immunopharmacology - October 1, 2015 Category: Allergy & Immunology Authors: Sahu D, Raghav SK, Gautam H, Das HR Tags: Int Immunopharmacol Source Type: research
Activity of Six Essential Oils Extracted from Tunisian Plants against Legionella pneumophila.
This study highlighted the potential interest of some essential oils extracted from Tunisian plants as biocides to prevent the Legionella risk.
PMID: 26460561 [PubMed - in process] (Source: Chemistry and Biodiversity)
Source: Chemistry and Biodiversity - October 1, 2015 Category: Biochemistry Authors: Chaftar N, Girardot M, Quellard N, Labanowski J, Ghrairi T, Hani K, Frère J, Imbert C Tags: Chem Biodivers Source Type: research
Homeopathic remedies with antineoplastic properties have immunomodulatory effects in experimental animals.
CONCLUSIONS: The results suggest immunomodulatory activity of homeopathic preparations in high dilution. This may be a mechanism through which homeopathic preparations act.
PMID: 26143455 [PubMed - in process] (Source: Homeopathy)
Source: Homeopathy - July 1, 2015 Category: Complementary Medicine Authors: Remya V, Kuttan G Tags: Homeopathy Source Type: research
Effects of aqueous extract of Ruta graveolens and its ingredients on cytochrome P450, uridine diphosphate (UDP)-glucuronosyltransferase, and reduced nicotinamide adenine dinucleotide (phosphate) (NAD(P)H)-quinone oxidoreductase in mice
Publication date: Available online 21 May 2015 Source:Journal of Food and Drug Analysis Author(s): Yune-Fang Ueng , Chien-Chih Chen , Yu-Ling Huang , I-Jung Lee , Chul-Ho Yun , Yu-Hsuan Chen , Chiung-Chiao Huang Ruta graveolens (the common rue) has been used for various therapeutic purposes, including relief of rheumatism and treatment of circulatory disorder. To elucidate the effects of rue on main drug-metabolizing enzymes, effects of an aqueous extract of the aerial part of rue and its ingredients on cytochrome P450 (P450/CYP), uridine diphosphate (UDP)-glucuronosyltransferase, and reduced nicotinamide adeni...
Source: Journal of Food and Drug Analysis - June 20, 2015 Category: Food Science Source Type: research
Effects of aqueous extract of Ruta graveolens and its ingredients on cytochrome P450, UDP-glucuronosyltransferase, and NAD(P)H-quinone oxidoreductase in mice
Publication date: Available online 21 May 2015 Source:Journal of Food and Drug Analysis Author(s): Yune-Fang Ueng , Chien-Chih Chen , Yu-Ling Huang , I-Jung Lee , Chul-Ho Yun , Yu-Hsuan Chen , Chiung-Chiao Huang Ruta graveolens (the common rue) has been used for various therapeutic purposes, including relief of rheumatism and treatment of circulatory disorder. To elucidate the effects of rue on main drug-metabolizing enzymes, effects of an aqueous extract of the aerial part of rue and its ingredients on cytochrome P450 (P450/CYP), UDP-glucuronosyltransferase, and NAD(P)H:quinone oxidoreductase were studied in C...
Source: Journal of Food and Drug Analysis - May 21, 2015 Category: Food Science Source Type: research
Essential oils as soil biofumigants for the control of the root‐knot nematode Meloidogyne incognita on tomato
Abstract
The effectiveness of soil fumigation with 50, 100 and 200 µL kg−1 soil of essential oils (EOs) from the plant species Eucalyptus citriodora, Eucalyptus globulus, Mentha piperita, Pelargonium asperum and Ruta graveolens was assessed against the root‐knot nematode Meloidogyne incognita on potted tomato. Plant growth parameters and number of galls, nematode eggs and juveniles on tomato roots were evaluated after two months of maintenance of the treated plants at 25°C in greenhouse. EOs of E. globulus and P. asperum significantly reduced nematode multiplication and gall formation on tomato roots at all the t...
Source: Annals of Applied Biology - May 1, 2015 Category: Biology Authors: S. Laquale, V. Candido, P. Avato, M.P. Argentieri, T. D'Addabbo Tags: RESEARCH ARTICLE Source Type: research
Evaluation of chemopreventive potentials of ethanolic extract of Ruta graveolens against A375 skin melanoma cells in vitro and induced skin cancer in mice in vivo
Conclusion Chemopreventive potential of RG was demonstrated from overall results of this study, indicating its possible use in therapeutic formulation of an effective drug to treat skin cancer. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 10, 2015 Category: Complementary Medicine Source Type: research
Immobilising effect of Ruta graveolens L. on human spermatozoa: coumarin compounds are involved
This study was designed to find out Ruta graveolens L. functional components, which have immobilisation effect on human spermatozoa for contraceptive use. A five‐step fractionation method was used to derive different components from rue aqueous extract by using hexane, chloroform, ethanol, acetone and ultrapure water. Gas chromatography–mass spectrophotometery (GC–MS) of all fractions and the aqueous extract were performed to determine the chemical components. The immobilisation assay and membrane integrity test were also performed with four different coumarins, which were found in GC–MS in a concentration of 10 ...
Source: Andrologia - January 29, 2015 Category: Urology & Nephrology Authors: M. R. Sadeghi, N. Lakpour, H. R. Sadeghipoor, M. Kamalinejad, M. R. Eshraghian, B. Naghibi, M. M. Akhondi, S. Binaafar, Z. N. Harat Tags: Original Article Source Type: research
DNA fragmentation and cell cycle arrest: a hallmark of apoptosis induced by Ruta graveolens in human colon cancer cells.
Abstract
In the present study, we investigated the anti-cancer effect of various potencies of Ruta graveolens (Ruta) on COLO-205 cell line, as evidenced by cytotoxicity, migration, clonogenecity, morphological and biochemical changes and modification in the levels of genes associated with apoptosis and cell cycle. On treatment of COLO-205 cells maximal effects were seen with mother tincture (MT) and 30C potencies, wherein decrease in cell viability along with reduced clonogenecity and migration capabilities were noted. In addition morphological and biochemical alterations such as nuclear changes (fragmente...
Source: Homeopathy - January 1, 2015 Category: Complementary Medicine Authors: Arora S, Tandon S Tags: Homeopathy Source Type: research
Open-label uncontrolled pilot study to evaluate complementary therapy with Ruta graveolens 9c in patients with advanced cancer.
CONCLUSION: Some patients treated with Ruta graveolens 9c had a transitory improvement in QoL, but the effectiveness of this treatment remains to be confirmed in further studies.
PMID: 25439039 [PubMed - in process] (Source: Homeopathy)
Source: Homeopathy - October 1, 2014 Category: Complementary Medicine Authors: Freyer G, You B, Villet S, Tartas S, Fournel-Federico C, Trillet-Lenoir V, Hamizi S, Colomban O, Chavernoz N, Falandry C Tags: Homeopathy Source Type: research
Discrete nanoparticles of ruta graveolens induces the bacterial and fungal biofilm inhibition
Cell Commun Adhes. 2014 Aug;21(4):229-38. doi: 10.3109/15419061.2014.926476.ABSTRACTRuta graveolens silver nanoparticles (AgNPs) showed the color change within 30 min and characterized using UV-visible spectra, Fourier Transform Infrared (FTIR), X-ray Diffraction (XRD) and Transmission Electron Microscopy (TEM). UV-visible spectrum of R. graveolens AgNPs showed the sharp peak at the wavelength of 440-560 nm. XRD patterns confirmed that crystalline nature of R. graveolens AgNPs and FTIR results revealed that phytochemical reaction of these R. graveolens is responsible for the synthesis of AgNPs. TEM results showed the size ...
Source: Cell Communication and Adhesion - July 25, 2014 Category: Molecular Biology Authors: Jeyachandran Sivakamavalli Oyyappan Deepa Baskaralingam Vaseeharan Source Type: research
