Phenolic content and in vitro antioxidant and anti-inflammatory evaluation of Algerian Ruta graveolens L
Chem Biodivers. 2022 Jul 22. doi: 10.1002/cbdv.202200545. Online ahead of print.ABSTRACTPlants constitute a valuable source of natural antioxidants such as polyphenols and are responsible for exhibiting many biologically significant functions. Ruta species including Ruta chalepensis L. and Ruta graveolens L are widespread species in Algeria and are used as medicinal plants to treat various diseases; however, so far, most of the conducted studies focused on analyzing alkaloids and essential oils mostly on R. chalepensis. The aim of the present research is to investigate the phenolic profile of the aerial parts of Ruta grave...
Source: Chemistry and Biodiversity - July 22, 2022 Category: Biochemistry Authors: Meriem Mokhtar Fatma Youcefi Soumia Keddari Yahia Saimi Siham Otsmane Elhao Francesco Cacciola Source Type: research
A Candidate for Health Promotion, Disease Prevention and Treatment, Common Rue (Ruta graveolens L.), an Important Medicinal plant in Traditional Medicine
CONCLUSION: According to pharmacological and phytochemical advantages, pennyroyal shows its importance as a medicinal plant in both modern medicinal science and traditional medicine.PMID:35538827 | DOI:10.2174/2772432817666220510143902 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - May 11, 2022 Category: Drugs & Pharmacology Authors: Mohamad Hesam Shahrajabian Source Type: research
A Candidate for Health Promotion, Disease Prevention and Treatment, Common Rue (Ruta graveolens L.), an Important Medicinal plant in Traditional Medicine
CONCLUSION: According to pharmacological and phytochemical advantages, pennyroyal shows its importance as a medicinal plant in both modern medicinal science and traditional medicine.PMID:35538827 | DOI:10.2174/2772432817666220510143902 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - May 11, 2022 Category: Drugs & Pharmacology Authors: Mohamad Hesam Shahrajabian Source Type: research
A Candidate for Health Promotion, Disease Prevention and Treatment, Common Rue (Ruta graveolens L.), an Important Medicinal plant in Traditional Medicine
CONCLUSION: According to pharmacological and phytochemical advantages, pennyroyal shows its importance as a medicinal plant in both modern medicinal science and traditional medicine.PMID:35538827 | DOI:10.2174/2772432817666220510143902 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - May 11, 2022 Category: Drugs & Pharmacology Authors: Mohamad Hesam Shahrajabian Source Type: research
Ruta graveolens, Peganum harmala, and Citrullus colocynthis methanolic extracts have in vitro protoscolocidal effects and act against bacteria isolated from echinococcal hydatid cyst fluid
In this study, the in vitro activities of methanolic extracts of Ruta graveolens, Peganum harmala aerial parts, and Citrullus colocynthis seeds against protoscolosis and isolated bacterial strains from hydatid cysts were assessed using disc diffusion methods and Minimum Inhibitory Concentration (MIC). The chemical composition of three methanolic extracts was studied using LC-MS. After 3 h of exposure to 40 mg/mL R. graveolens extract, a tenfold protoscolocidal effect was seen when compared to the convintional medication (ABZ) for the same duration (P < 0.05). The bacteria listed below were isolated from hydatid cyst flu...
Source: Archives of Microbiology - March 30, 2022 Category: Microbiology Authors: Yaseen T Al Qaisi Khaled M Khleifat Sawsan A Oran Amjad A Al Tarawneh Haitham Qaralleh Talal S Al-Qaisi Husni S Farah Source Type: research
Comparison of Herbal Medicines Used for Women ’s Menstruation Diseases in Different Areas of the World
Conclusion: Women’s menstruation health is directly related to their health condition. Traditional medicines of most ethnic groups have contributed to women’s health care and treatment of gynecological diseases. Practitioners in this field have gained elaborate experience in treatments and medication, and assembled a large number of effective drugs and prescriptions. These experiences have also been inherited and developed by modern clinical application and scientific research. However, the basic research on these drugs is not sufficient, the knowledge of drug use has not been fully popularized, the advantages of drugs...
Source: Frontiers in Pharmacology - February 4, 2022 Category: Drugs & Pharmacology Source Type: research
Tanning Beds, Rue, and Major Burns: An Alarming Association
We present a major burns case report associated with the use of rue (an herb used in Colombia for cultural beliefs) before entering a tanning bed. The patient presented superficial wounds that evolved to deeper ones in a phytophotodermatitis reaction that acted as a chemical burn. The patient presented an estimated percentage of total burn surface area of 85% with second-degree burns. It took two and a half months to apply multiple debridements and bandage coverage before discharge. One month later, the patient presented a dark purplish pigmentation mainly in the lower limbs. Since ancient times, rue has been used as part ...
Source: Plastic and Reconstructive Surgery – Global Open - February 1, 2022 Category: Cosmetic Surgery Tags: Reconstructive: Case Report Source Type: research
Chemical constituents of Ruta graveolens L. and their melanogenic effects and action mechanism
In this study, we isolated a new furanocoumarin named Rutagrarin (1) along with 14 known compounds (2-15) from the aerial parts of R. graveolens and elucidated their chemical structures via various spectroscopy. We found that compound 5 promoted melanogenesis and tyrosinase activity in B16 cells. Further investigation on underlying mechanisms revealed that compound 5 activated the transcription of microtia-related transcription factors and promoted the production of melanin in B16 cells via the Akt/GSK-3β/β-catenin pathway. Therefore, we confirmed the traditional efficacy of R. graveolens and speculated that compound 5 c...
Source: Fitoterapia - December 3, 2021 Category: Biochemistry Authors: Pazilaiti Ainiwaer Mayire Nueraihemaiti Zuopeng Li Deng Zang Lan Jiang Ying Li Haji Akber Aisa Source Type: research
Chemical constituents of Ruta graveolens L. and their melanogenic effects and action mechanism
In this study, we isolated a new furanocoumarin named Rutagrarin (1) along with 14 known compounds (2-15) from the aerial parts of R. graveolens and elucidated their chemical structures via various spectroscopy. We found that compound 5 promoted melanogenesis and tyrosinase activity in B16 cells. Further investigation on underlying mechanisms revealed that compound 5 activated the transcription of microtia-related transcription factors and promoted the production of melanin in B16 cells via the Akt/GSK-3β/β-catenin pathway. Therefore, we confirmed the traditional efficacy of R. graveolens and speculated that compound 5 c...
Source: Fitoterapia - December 3, 2021 Category: Biochemistry Authors: Pazilaiti Ainiwaer Mayire Nueraihemaiti Zuopeng Li Deng Zang Lan Jiang Ying Li Haji Akber Aisa Source Type: research
Chemical constituents of Ruta graveolens L. and their melanogenic effects and action mechanism
In this study, we isolated a new furanocoumarin named Rutagrarin (1) along with 14 known compounds (2-15) from the aerial parts of R. graveolens and elucidated their chemical structures via various spectroscopy. We found that compound 5 promoted melanogenesis and tyrosinase activity in B16 cells. Further investigation on underlying mechanisms revealed that compound 5 activated the transcription of microtia-related transcription factors and promoted the production of melanin in B16 cells via the Akt/GSK-3β/β-catenin pathway. Therefore, we confirmed the traditional efficacy of R. graveolens and speculated that compound 5 c...
Source: Fitoterapia - December 3, 2021 Category: Biochemistry Authors: Pazilaiti Ainiwaer Mayire Nueraihemaiti Zuopeng Li Deng Zang Lan Jiang Ying Li Haji Akber Aisa Source Type: research
Chemical constituents of Ruta graveolens L. and their melanogenic effects and action mechanism
In this study, we isolated a new furanocoumarin named Rutagrarin (1) along with 14 known compounds (2-15) from the aerial parts of R. graveolens and elucidated their chemical structures via various spectroscopy. We found that compound 5 promoted melanogenesis and tyrosinase activity in B16 cells. Further investigation on underlying mechanisms revealed that compound 5 activated the transcription of microtia-related transcription factors and promoted the production of melanin in B16 cells via the Akt/GSK-3β/β-catenin pathway. Therefore, we confirmed the traditional efficacy of R. graveolens and speculated that compound 5 c...
Source: Fitoterapia - December 3, 2021 Category: Biochemistry Authors: Pazilaiti Ainiwaer Mayire Nueraihemaiti Zuopeng Li Deng Zang Lan Jiang Ying Li Haji Akber Aisa Source Type: research
Chemical constituents of Ruta graveolens L. and their melanogenic effects and action mechanism
In this study, we isolated a new furanocoumarin named Rutagrarin (1) along with 14 known compounds (2-15) from the aerial parts of R. graveolens and elucidated their chemical structures via various spectroscopy. We found that compound 5 promoted melanogenesis and tyrosinase activity in B16 cells. Further investigation on underlying mechanisms revealed that compound 5 activated the transcription of microtia-related transcription factors and promoted the production of melanin in B16 cells via the Akt/GSK-3β/β-catenin pathway. Therefore, we confirmed the traditional efficacy of R. graveolens and speculated that compound 5 c...
Source: Fitoterapia - December 3, 2021 Category: Biochemistry Authors: Pazilaiti Ainiwaer Mayire Nueraihemaiti Zuopeng Li Deng Zang Lan Jiang Ying Li Haji Akber Aisa Source Type: research
Medicinal Plants for Mitigating Pain and Inflammatory-Related Conditions: An Appraisal of Ethnobotanical Uses and Patterns in South Africa
In South Africa, traditional medicine remains the first point of call for a significant proportion of the population seeking primary healthcare needs. This is particularly important for treating common conditions including pain and inflammation which are often associated with many disease conditions. This review focuses on the analysis of the trend and pattern of plants used for mitigating pain and inflammatory-related conditions in South African folk medicine. An extensive search was conducted using various scientific databases and popular ethnobotanical literature focusing on South African ethnobotany. Based on the syste...
Source: Frontiers in Pharmacology - October 22, 2021 Category: Drugs & Pharmacology Source Type: research
Efficacy of Individualized Homeopathic Medicines in Plantar Fasciitis: Double-blind, Randomized, Placebo-Controlled Clinical Trial
CONCLUSION: IHMs acted significantly better than placebo in the treatment of PF; however, the trial being underpowered, the results should be interpreted as preliminary only. Independent replications are warranted.TRIAL REGISTRATION: CTRI/2018/10/016014.PMID:34492725 | DOI:10.1055/s-0041-1731383 (Source: Homeopathy)
Source: Homeopathy - September 7, 2021 Category: Complementary Medicine Authors: Sana Shahid Shubhamoy Ghosh Ardhendu Shekhar Chakraborty Shukdeb Maiti Satarupa Sadhukhan Munmun Koley Subhranil Saha Source Type: research
Efficacy of Individualized Homeopathic Medicines in Plantar Fasciitis: Double-blind, Randomized, Placebo-Controlled Clinical Trial
CONCLUSION: IHMs acted significantly better than placebo in the treatment of PF; however, the trial being underpowered, the results should be interpreted as preliminary only. Independent replications are warranted.TRIAL REGISTRATION: CTRI/2018/10/016014.PMID:34492725 | DOI:10.1055/s-0041-1731383 (Source: Homeopathy)
Source: Homeopathy - September 7, 2021 Category: Complementary Medicine Authors: Sana Shahid Shubhamoy Ghosh Ardhendu Shekhar Chakraborty Shukdeb Maiti Satarupa Sadhukhan Munmun Koley Subhranil Saha Source Type: research
