Editorial Board
Publication date: May 2019Source: Journal of Integrative Medicine, Volume 17, Issue 3Author(s): (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - April 24, 2019 Category: Complementary Medicine Source Type: research

Qigong in the treatment of children with autism spectrum disorder: a systematic review
ConclusionStudies demonstrated that Qigong has interesting and promising applicability and effect on children with autism spectrum disorder and should be tested further. Despite the need for more rigorous controlled studies, Qigong seems to be able to decrease severity of individual sensory, behavioural, and language components of autism, and improve self-control, sociability, sensory and cognitive awareness as well as healthy-physical behaviour. Besides positive effect on children and adolescents, benefits seem to extend to parents and caregivers as well. However, quality of methodology seems to be insufficient to state t...
Source: Journal of Integrative Medicine - April 20, 2019 Category: Complementary Medicine Source Type: research

In vitro antilithiatic activity of the hydro-alcoholic extract of Cinnamomum zeylanicum Blume bark on calcium oxalate crystallization
Publication date: Available online 4 April 2019Source: Journal of Integrative MedicineAuthor(s): Sana Zaki, Nasreen Jahan, Mohd Kalim, Ghausia IslamAbstractObjectiveThe study examines the effect of the hydro-alcoholic extract of Cinnamomum zeylanicum Blume bark on crystallization of calcium oxalate.MethodsThe antilithiatic effect of various concentrations of the hydro-alcoholic extract of C. zeylanicum was investigated at various stages of stone formation, using Cystone as a standard reference drug. The effect on calcium oxalate crystallization was evaluated by measuring the change in turbidity over time, during crystal nu...
Source: Journal of Integrative Medicine - April 6, 2019 Category: Complementary Medicine Source Type: research

Potential of phloroglucinol to improve erectile dysfunction associated with streptozotocin-induced diabetes in rats
ConclusionThe results highlight the protective effect of phloroglucinol in diabetes-induced ED in rats warranting further studies. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - April 6, 2019 Category: Complementary Medicine Source Type: research

The present state of complementary medicine regulation in Saudi Arabia
This article briefly highlights the current state of complementary medicine regulation in Saudi Arabia. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 29, 2019 Category: Complementary Medicine Source Type: research

Burnout in the emergency department: randomized controlled trial of an attention-based training program
Publication date: Available online 29 March 2019Source: Journal of Integrative MedicineAuthor(s): Pádraic J. Dunne, Julie Lynch, Lucia Prihodova, Caoimhe O'Leary, Atiyeh Ghoreyshi, Sharee A. Basdeo, Donal J. Cox, Rachel Breen, Ali Sheikhi, Áine Carroll, Cathal Walsh, Geraldine McMahon, Barry WhiteAbstractBackgroundBurnout (encompassing emotional exhaustion, depersonalization and personal accomplishment) in healthcare professionals is a major issue worldwide. Emergency medicine physicians are particularly affected, potentially impacting on quality of care and attrition from the specialty.ObjectiveThe aim of th...
Source: Journal of Integrative Medicine - March 29, 2019 Category: Complementary Medicine Source Type: research

Medicine has always been “Modern” and “Scientific” from ancient times to the present day
Publication date: Available online 29 March 2019Source: Journal of Integrative MedicineAuthor(s): Mikhail TepponeAbstractThroughout human history, doctors and healers have gathered and refined the knowledge inherited from the previous generations. Different methods of effective therapy have been designed during various historical periods; when each was developed, it was considered “modern scientific medicine” for their time. Mankind has gone through natural and social disasters and survived; hence, history has proved there was no time when medical knowledge was erroneous or ineffective. Classic medicine has gro...
Source: Journal of Integrative Medicine - March 29, 2019 Category: Complementary Medicine Source Type: research

Interactive antimicrobial and toxicity profiles of Pittosporum angustifolium Lodd. extracts with conventional antimicrobials
ConclusionP. angustifolium leaf extracts inhibit the growth of pathogenic triggers of some autoimmune diseases. Some extracts also potentiated the activity of conventional antibiotics, without significantly affecting the toxicity of the combination. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 28, 2019 Category: Complementary Medicine Source Type: research

Halalopathy: a science of trust in medicine
This study enlightens laws of compatibility to initiate a domino chain effect to activate placebo effects and lower the body’s entropy. The healing power of each effect will contribute to the healing process and enhance the total drug effects.Please cite this article as: Alzeer J. Halalopathy: a science of trust in medicine. J Integr Med. 2019; Epub ahead of print. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 25, 2019 Category: Complementary Medicine Source Type: research

Induction of apoptosis in leukemic cells by the alkaloid extract of garden cress (Lepidium sativum L.)
ConclusionThe ability of the alkaloid extract of L. sativum seeds to induce apoptosis indicates a potential pharmacological use in cancer chemotherapy. The separation of individual active compounds and further in-depth exploration of the molecular mechanism of apoptosis may lead to novel chemotherapeutic compounds in our future antineoplastic research. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 25, 2019 Category: Complementary Medicine Source Type: research

Ursolic acid: an overview on its cytotoxic activities against breast and colorectal cancer cells
Publication date: Available online 18 March 2019Source: Journal of Integrative MedicineAuthor(s): Eric Wei Chiang Chan, Chu Yong Soon, Joash Ban Lee Tan, Siu Kuin Wong, Yew Woh HuiAbstractUrsolic acid (UA) is a pentacyclic triterpene of the ursane type. As a common chemical constituent among species of the family Lamiaceae, UA possesses a broad spectrum of pharmacological properties. This overview focuses on the anticancer properties of UA against breast cancer (BC) and colorectal cancer (CRC) that are most common among women and men, respectively. In vitro studies have shown that UA inhibited the growth of BC and CRC cell...
Source: Journal of Integrative Medicine - March 20, 2019 Category: Complementary Medicine Source Type: research

Fire-needle acupuncture for upper limb spastic paralysis after stroke: study protocol for a randomized controlled trial
This study will evaluate the effects of fire-needle acupuncture for ULSP in the context of standardized clinical research and provide high-quality data to inform clinical procedures and future study design.Methods/DesignA randomized controlled trial will be carried out to evaluate the effects of fire-needle acupuncture therapy in patients with ULSP from stroke. ULSP patients (n = 120) will be recruited at Changhai Hospital in Shanghai, China. Patients will be randomly divided into three groups, including fire-needle acupuncture group (FAG), filiform-needle acupuncture group (FFAG) and rehabilitation treatment group (RTG). ...
Source: Journal of Integrative Medicine - March 20, 2019 Category: Complementary Medicine Source Type: research

Editorial Board
Publication date: March 2019Source: Journal of Integrative Medicine, Volume 17, Issue 2Author(s): (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 16, 2019 Category: Complementary Medicine Source Type: research

Discovery and preclinical development of IIIM-160, a Bergenia ciliata-based anti-inflammatory and anti-arthritic botanical drug candidate
ConclusionThe dual-activity of IL-6 inhibition and antinociception marks the suitability of IIIM-160 for treating rheumatoid arthritis. This study will serve as the benchmark for further research on this botanical formulation. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 7, 2019 Category: Complementary Medicine Source Type: research

Evaluation of in vitro cell and blood compatibility and in vivo analgesic activity of plant-derived dietary supplements
ConclusionNo hemotoxicity and good cell compatibility were found for all the tested samples. GA and Eq were the best candidates for further biocompatibility testing. Moreover, GA reduced pain in the animal model. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 28, 2019 Category: Complementary Medicine Source Type: research

Scientific papers: which type would you prefer?
Publication date: Available online 20 February 2019Source: Journal of Integrative MedicineAuthor(s): Chun-song HuAbstractIt’s very important to enhance the quality of scientific papers produced by postgraduates and scholars from academic institutions. To encourage their academic and professional development, these young scientists should be encouraged to compose nonresearch articles, in addition to original research articles, including short essays, perspectives and reviews. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 21, 2019 Category: Complementary Medicine Source Type: research

Antioxidant and antihyperlipidemic activity of Costus speciosus against atherogenic diet-induced hyperlipidemia in rabbits
ConclusionThe present findings indicate that the C. speciosus rhizome possesses antiatherogenic and antioxidant properties which may provide protective effects against oxidative stress in atherosclerotic rabbits. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 13, 2019 Category: Complementary Medicine Source Type: research

Medicinal properties of Angelica archangelica root extract: cytotoxicity in breast cancer cells and its protective effects against in vivo tumor development
ConclusionAltogether, our data show the antitumor potential of the CEAA against breast cancer cells in vitro and in vivo. Further research is necessary to better elucidate the pharmacological application of the CEAA in breast cancer therapy. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 9, 2019 Category: Complementary Medicine Source Type: research

Icariin protects vascular endothelial cells from oxidative stress through inhibiting endoplasmic reticulum stress
ConclusionThe results showed the dose-dependent effects of ICA against H2O2-induced injury in vascular endothelial cells. The inhibition of GRP78, ATF4 and eIF2α protein expressions in the ERS, and the subsequent alleviation of oxidative stress damage, might be the molecular mechanism.Please cite this article as: Wang FY, Jia J, Song HH, Jia CM, Chen CB, Ma J. Icariin protects vascular endothelial cells from oxidative stress through inhibiting endoplasmic reticulum stress. J Integr Med. 2019; Epub ahead of print. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 1, 2019 Category: Complementary Medicine Source Type: research

Impact of high-fat diet and vitamin D3 supplementation on aortic stenosis establishment in waved-2 epidermal growth factor receptor mutant mice‘
ConclusionThese results suggest that HFD and vitamin D3 supplementation have no effect in the waved-2 mice model. This model essentially mimics AR and rarely AS. Further studies are needed to find a reliable animal model of AS. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 31, 2019 Category: Complementary Medicine Source Type: research

Evidence for the efficacy and safety of herbal weight loss preparations
Publication date: Available online 30 January 2019Source: Journal of Integrative MedicineAuthor(s): Rachael Farrington, Ian F. Musgrave, Roger W. ByardAbstractRising rates of obesity across the globe have been associated with an increase in the use of herbal preparations for weight control. However, the mechanisms of action for these substances are often not known, as is the potential for interaction with other herbal preparations or prescription pharmaceutical drugs. To investigate the reported efficacy and safety of herbal weight loss preparations, we conducted a review of the literature focusing on herbs that are most c...
Source: Journal of Integrative Medicine - January 31, 2019 Category: Complementary Medicine Source Type: research

Effects of geraniin (rambutan rind extract) on blood pressure and metabolic parameters in rats fed high-fat diet
ConclusionGeraniin at lower doses improved blood pressure and other metabolic parameters. Secondary metabolites of geraniin, associated with antihypertensive activity, are relatively different to those involved in inhibiting AGE formation and increasing insulin sensitivity. The secondary metabolites of geraniin may be individually responsible for the bioactivities demonstrated. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 30, 2019 Category: Complementary Medicine Source Type: research

Chenopodium ambrosioides induces an endothelium-dependent relaxation of rat isolated aorta
ConclusionThese results suggest that the MF of C. ambrosioides produces an endothelium-dependent relaxation of the isolated rat aorta, which is thought to be mediated mainly through stimulation of the muscarinic receptors, and probably involving the opening of Ca2+-activated potassium channels. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 29, 2019 Category: Complementary Medicine Source Type: research

Effects of acupuncture in treating insomnia due to spleen-stomach disharmony syndrome and its influence on intestinal microbiome: study protocol for a randomized controlled trial
DiscussionThe results of this trial are expected to confirm that “harmonizing stomach to tranquilize mind” acupuncture can effectively relieve insomnia and alter the intestinal microbiome.Trial registrationChinese Clinical Trials Registry: ChiCTR1800017092. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 29, 2019 Category: Complementary Medicine Source Type: research

Discussions on real-world acupuncture treatments for chronic low-back pain in older adults
Publication date: Available online 26 January 2019Source: Journal of Integrative MedicineAuthor(s): Arthur Yin Fan, Hui Ouyang, Xinru Qian, Hui Wei, David Dehui Wang, Deguang He, Haihe Tian, Changzhen Gong, Amy Matecki, Sarah Faggert Alemi (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 26, 2019 Category: Complementary Medicine Source Type: research

Periconceptional care and offspring health at birth and long term, from the perspective of Avicenna
Publication date: Available online 11 January 2019Source: Journal of Integrative MedicineAuthor(s): Mohammad Ansaripour, Mohsen Naseri, Mohammad Mahdi Esfahani, Iraj Nabipour, Fatemeh Rakhshani, Arman Zargaran, Roya KelishadiAbstractPericonceptional care such as lifestyle plays an important impact role in offspring health. The aim of the present study was to clarify the perspective of Avicenna on periconceptional care. Avicenna (980–1037 A.D.) was one of the outstanding Persian physicians, who made great contributions to the field of medical sciences, in particular, obstetrics. In advance, Avicenna’s book, Cano...
Source: Journal of Integrative Medicine - January 12, 2019 Category: Complementary Medicine Source Type: research

Extract of Emblica officinalis enhances the growth of human keratinocytes in culture
ConclusionThe extract of E. officinalis enhanced the growth of human keratinocytes in culture. E. officinalis contains the compounds that would be beneficial for human skin health because enhanced growth of keratinocytes would promote wound healing. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 12, 2019 Category: Complementary Medicine Source Type: research

Editorial Board
Publication date: January 2019Source: Journal of Integrative Medicine, Volume 17, Issue 1Author(s): (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 8, 2019 Category: Complementary Medicine Source Type: research

Integrative herbal treatments of diabetes in Beni Mellal region of Morocco
ConclusionThe Beni Mellal region of Morocco has an important floristic biodiversity of plants used to treat diabetes in traditional medicinal practice. This result provides a good database for pharmacological screenings in the search for plant-based antidiabetic medications. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 5, 2019 Category: Complementary Medicine Source Type: research

Neuromodulatory effects of ethyl acetate fraction of Zingiber officinale Roscoe extract in rats with lead-induced oxidative stress
This study investigated the ameliorative potential of Zingiber officinale Roscoe extract against lead-induced brain damage in rats.MethodsThirty male rats were divided into 5 groups of 6 rats each. Lead-acetate toxicity was induced by intraperitoneal injection (10 mg/kg body weight [b.w.]) in Groups B–E. Group A (control) and Group B (lead-acetate) were left untreated; vitamin C (200 mg/kg b.w.) was administered to Group C; ethyl acetate fraction from Z. officinale extract (200 and 100 mg/kg b.w.) was administered to Group D and E by oral gavage once daily for 7 days. Changes in the content of some key marker enzymes...
Source: Journal of Integrative Medicine - January 5, 2019 Category: Complementary Medicine Source Type: research

Effects of Tualang honey in modulating nociceptive responses at the spinal cord in offspring of prenatally stressed rats
ConclusionThis study provides a preliminary understanding of the beneficial effects of Tualang honey against the changes in oxidative stress and neuronal damage in the spinal cord of the offspring of prenatally stressed rats. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - December 15, 2018 Category: Complementary Medicine Source Type: research

Antidiarrheal and protein conservative activities of Psidium guajava in diarrheal rats
ConclusionP. guajava leaf extract elicited antidiarrheal and protein conservative effects. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - December 5, 2018 Category: Complementary Medicine Source Type: research

Telfairia occidentalis (Cucurbitaceae) pulp extract mitigates rifampicin-isoniazid-induced hepatotoxicity in an in vivo rat model of oxidative stress
Publication date: Available online 1 December 2018Source: Journal of Integrative MedicineAuthor(s): Lucky Legbosi Nwidu, Yibala Ibor ObomaAbstractObjectiveDrug-induced liver injury complicates antituberculosis drug treatment and is a leading cause of death worldwide. The aim of this study is to establish the ethnomedicinal claim of hepatoprotective effects of fruit pulp extract of Telfairia occidentalis against rifampicin (RIF) and isoniazid (INH)-induced oxidative stress in rats.MethodsT. occidentalis pulp extract (TOPE) (125–500 mg/kg) and silymarin (50 mg/kg) were evaluated in an induced hepatotoxicity model of ox...
Source: Journal of Integrative Medicine - December 1, 2018 Category: Complementary Medicine Source Type: research

Safe acupuncture and dry needling during pregnancy: New Zealand physiotherapists’ opinion and practice
ConclusionConflicting literature and a “fear of blame” influences NZ physiotherapists’ decisions to offer needling (both acupuncture and DN) during pregnancy. Further training in this field is recommended to ensure safe practice and adequate provision of acupuncture treatment options for pregnant women suffering musculoskeletal pain, such as LBP and PGP. Further research, particularly into DN, for women during pregnancy, is warranted. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - November 29, 2018 Category: Complementary Medicine Source Type: research

Acupuncture in living liver and kidney donors: a feasibility study
ConclusionPreliminary findings suggest it is feasible to integrate acupuncture into inpatient recovery for living organ donation. Tailoring interventions to the specific needs of patients is important to address ongoing concerns. Larger studies are needed to further ascertain benefits of peri-operative acupuncture. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - November 28, 2018 Category: Complementary Medicine Source Type: research

Integration of AYUSH and allopathy—pros and cons
Publication date: Available online 22 November 2018Source: Journal of Integrative MedicineAuthor(s): Preethi MohanAbstractAYUSH is an assembly of medical systems (Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homeopathy) that are practiced in India. There are various faulty notions about its practices. The author perceived one research article published in Journal of Integrative Medicine about the need to integrate AYUSH into the curriculum of allopathy. Integration is an approach open to alternate systems of medicine with other streams for their advancements through research and it explores new horizons of health prac...
Source: Journal of Integrative Medicine - November 23, 2018 Category: Complementary Medicine Source Type: research

Dietary supplementation with turmeric polyherbal formulation decreases facial redness: a randomized double-blind controlled pilot study
ConclusionPolyherbal combination tablet supplementation improved facial redness compared to the turmeric or placebo. Overall, our findings suggested further investigations into the effects of turmeric and polyherbal formulations in skin conditions associated with facial redness would be warranted.Trial registrationClinicalTrials.gov identifier: NCT03065504 (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - November 23, 2018 Category: Complementary Medicine Source Type: research

Effectiveness of hand self-shiatsu to improve sleep following sport-related concussion in young athletes: a proof-of-concept study
ConclusionThese findings support the hypothesis that HSS has the potential to improve sleep and reduce daytime fatigue in young postconcussion athletes. This pilot study provides guidance to refine research protocols and lays a foundation for further, large-sample, controlled studies. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - November 18, 2018 Category: Complementary Medicine Source Type: research

Internet survey on the provision of complementary and alternative medicine in Japanese private clinics: a cross-sectional study
ConclusionKampo medicines represent the most commonly used CAM in private clinics in Japan, and universal national health insurance coverage is considered to be the reason for the high rate of their use. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - November 18, 2018 Category: Complementary Medicine Source Type: research

Efficacy of equine-assisted psychotherapy in veterans with posttraumatic stress disorder
CONCLUSIONAs compared to the control group, a 6-week EAP program did not produce a statistically significant difference with respect to PCL-M and CD-RISC scores, or salivary cortisol. However, our results suggest that EAP may work as well as standard therapy with respect to these parameters. This study supports further inquiry into EAP as a potentially efficacious alternative for veterans suffering from PTSD. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - November 16, 2018 Category: Complementary Medicine Source Type: research

Effectiveness of two different acupuncture strategies in patients with vulvodynia: study protocol for a pilot pragmatic controlled trial
This study evaluates two different acupuncture strategies for the treatment of vulvodynia and aims to evaluate whether either of the acupuncture protocols reduce vulvar pain, pain duration or pain with intercourse. The study also examines how long the effect of acupuncture lasts in women with vulvodynia.Methods/designThe study is designed as a randomized controlled trial, focused on two acupuncture protocols. Fifty-one patients who have had vulvodynia for more than 3 months will be recruited. Among them, 34 patients will be randomized into Groups 1a and 1b; those who are unwilling to receive acupuncture will be recruited i...
Source: Journal of Integrative Medicine - October 10, 2018 Category: Complementary Medicine Source Type: research

Electro-acupuncture regulates the cholinergic anti-inflammatory pathway in a rat model of chronic obstructive pulmonary disease
In this study, we investigated whether electro-acupuncture (EA) affects the CAP in COPD.MethodsSprague-Dawley rats were induced into COPD through exposure to cigarette smoke combined with lipopolysaccharide. EA treatment was applied at Zusanli (ST36) and Feishu (BL13) points for 30 min/d for 7 d. Seventy-two rats were randomly divided into six study groups, including normal, normal + EA, normal + α-bungarotoxin (α-BGT) (the antagonist of the nicotinic acetylcholine receptor α7 subunit (α7nAChR)) + EA, COPD, COPD + EA, and COPD + α-BGT + EA. Lung function, pathology and vagus nerve discharge we...
Source: Journal of Integrative Medicine - October 6, 2018 Category: Complementary Medicine Source Type: research

An overview of the contribution of acupuncture to thyroid disorders
Publication date: Available online 6 October 2018Source: Journal of Integrative MedicineAuthor(s): Fung-Kei ChengAbstractThyroid dysfunction, affecting people of all ages, not only damages human growth and energy metabolism but is also comorbid with other illnesses such as cardiovascular disease, kidney disease and gastrointestinal disorders. With the increasing acceptance of alternative and complementary therapies, acupuncture, a traditional Chinese medical practice, has also been employed to address this problem. Analysing 29 clinical projects that were retrieved from 29 major digital databases and include 1757 patients ...
Source: Journal of Integrative Medicine - October 6, 2018 Category: Complementary Medicine Source Type: research

Anti-adipogenic effect of flavonoids from Chromolaena odorata leaves in 3T3-L1 adipocytes
ConclusionC. odorata leaves contained several flavonoids with anti-adipogenic effects against lipid accumulation in 3T3-L1 adipocytes. The plant, normally considered a useless weed, may actually provide an abundant source of biologically active flavonoids.Please cite this article as: Kumkarnjana S, Nimmannit U, Koobkokkruad T, Pattamadilok C, Suttisri R, Vardhanabhuti N. Anti-adipogenic effect of flavonoids from Chromolaena odorata leaves in 3T3-L1 adipocytes. J Integr Med. 2018; Epub ahead of print. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - October 5, 2018 Category: Complementary Medicine Source Type: research

Cytotoxic and antiproliferative activity of kanchnar guggulu, an Ayurvedic formulation
ConclusionKanchnar guggulu exhibited a cytotoxic effect by inhibiting cell division (antimitotic) and reducing cell proliferation. These results substantiate its potential for the treatment of cancer and support its traditional use in the treatment of cancer.Please cite this article as: Tomar P, Dey YN, Sharma D, Wanjari MM, Gaidhani S, Jadhav A. Cytotoxic and antiproliferative activity of kanchnar guggulu, an Ayurvedic formulation. J Integr Med. 2018; Epub ahead of print. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - October 5, 2018 Category: Complementary Medicine Source Type: research

The use of a standardized Chinese herbal formula in patients with advanced lung cancer: a feasibility study
ConclusionThis study provides preliminary evidence that short-term use of a carefully selected and prepared CH formula in patients with stage 4 NSCLC is acceptable and safe. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - September 22, 2018 Category: Complementary Medicine Source Type: research

In vitro antileishmanial effects of Physalis angulata root extract on Leishmania infantum
ConclusionAEPa presented antileishmanial activity against the promastigotes and amastigotes of L. infantum without macrophage cytotoxicity; these results show that natural products such as P. angulata have leishmanicidal potential and in the future may be an alternative treatment for leishmaniasis. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - August 25, 2018 Category: Complementary Medicine Source Type: research

Far infrared-emitting ceramics decrease Freund’s adjuvant-induced inflammatory hyperalgesia in mice through cytokine modulation and activation of peripheral inhibitory neuroreceptors
Publication date: Available online 11 August 2018Source: Journal of Integrative MedicineAuthor(s): Ralph Fernando Rosas, Aline Armiliato Emer, Ana Paula Batisti, Daniela Dero Ludtke, Bruna Turnes Lenfers, Franciane Bobinski, Francisco José Cidral-Filho, Daniel Fernandes MartinsAbstractObjectiveThe present study aimed to evaluate the analgesic and anti-inflammatory effects of far infrared-emitting ceramics (cFIRs) in a model of persistent inflammatory hyperalgesia and to elucidate the possible mechanisms of these effects.MethodsMice were injected with complete Freund’s adjuvant (CFA) and treated with cFIRs via ...
Source: Journal of Integrative Medicine - August 12, 2018 Category: Complementary Medicine Source Type: research

Synergistic effects of combined therapy of curcumin and Fructus Ligustri Lucidi for treatment of osteoporosis: cellular and molecular evidence of enhanced bone formation
ConclusionThe co-administration of CUR and FLL had superior promotion of elements of bone regeneration in cultured cells, thus could be a promising alternative herbal therapy for the management of bone erosive disorders such as osteoporosis.Please cite this article as: Bukhari SNA, Hussain F, Thu HE, Hussain Z. Synergistic efficacy of combined therapy of curcumin and Fructus Ligustri Lucidi for treatment of osteoporosis: cellular and molecular evidence of enhanced bone formation. J Integr Med. 2018; Epub ahead of print. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - August 11, 2018 Category: Complementary Medicine Source Type: research

Evaluation of in vitro antioxidant, antiglycation and antimicrobial potential of indigenous Myanmar medicinal plants
ConclusionThe results suggest that these plants are potential sources of antioxidants with free radicals-scavenging and antiglycation activities and could be useful for decreasing the oxidative stress and glycation end-products formation in glycation-related diseases.Please cite this article as: Moe TS, Win HH, Hlaing TT, Lwin WW, Htet ZM, Mya KM. Evaluation of in vitro antioxidant, antiglycation and antimicrobial potential of indigenous Myanmar medicinal plants. J Integr Med. 2018; Epub ahead of print. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - August 5, 2018 Category: Complementary Medicine Source Type: research