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Infectious Disease: COVID-19
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Total 239975 results found since Jan 2013.
Preclinical evaluation of a SARS-CoV-2 variant B.1.351-based candidate DNA vaccine
Vaccine. 2023 Sep 17:S0264-410X(23)01091-5. doi: 10.1016/j.vaccine.2023.09.021. Online ahead of print.ABSTRACTThe SARS-CoV-2 pandemic revealed the critical shortfalls of global vaccine availability for emergent pathogens and the need for exploring additional vaccine platforms with rapid update potential in response to new variants. Thus, it remains essential, for the present evolving SARS-CoV-2/Covid-19 and future pandemics, to continuously develop and characterize new and different vaccine platforms. Here, we describe an expression-optimized DNA vaccine candidate based on the SARS-CoV-2 spike protein of the Beta variant (...
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Ria Lassauni ère Charlotta Polacek Jeanette Linnea Tingstedt Anders Fomsgaard Source Type: research
Suicidal ideation and suicide attempts in psychiatric patients during the COVID-19: a systematic review and meta-analysis - Zhu Y, Li Y, Xu X.
Current suicidal ideation and suicide attempts among psychiatric patients during the COVID-19 pandemic were studied through systematic review and meta-analysis. We searched the following electronic databases using the relevant search terms: Medline, Embase...
Source: SafetyLit - September 19, 2023 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
Transcriptome-based analysis of human peripheral blood reveals regulators of immune response in different viral infections
DiscussionThe identified relationships between some of them and virus-induced alteration of immune functions are new and have not been found earlier, e.g., receptors for autocrine motility factor, insulin, prolactin, angiotensin II, and immunoglobulin epsilon. Modulation of the identified receptors can be investigated as one of therapeutic strategies for the treatment of severe viral infections.
Source: Frontiers in Immunology - September 19, 2023 Category: Allergy & Immunology Source Type: research
Molecules, Vol. 28, Pages 6696: Antiviral Effect of 5 & prime;-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection
Molecules, Vol. 28, Pages 6696: Antiviral Effect of 5′-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection
Molecules doi: 10.3390/molecules28186696
Authors:
Amanda Resende Tucci
Raquel Mello da Rosa
Alice Santos Rosa
Otávio Augusto Chaves
Vivian Neuza Santos Ferreira
Thamara Kelcya Fonseca Oliveira
Daniel Dias Coutinho Souza
Nathalia Roberto Resende Borba
Luciano Dornelles
Nayra Salazar Rocha
João Candido Pilar Mayer
João B. Teixeira da Rocha
Oscar Endrigo D. Rodrigues
Milene Dias Miranda
The understanding that zidovudine (ZDV or azidothymidine, AZT) inhibits t...
Source: Molecules - September 19, 2023 Category: Chemistry Authors: Amanda Resende Tucci Raquel Mello da Rosa Alice Santos Rosa Ot ávio Augusto Chaves Vivian Neuza Santos Ferreira Thamara Kelcya Fonseca Oliveira Daniel Dias Coutinho Souza Nathalia Roberto Resende Borba Luciano Dornelles Nayra Salazar Rocha Jo ão Candido Tags: Article Source Type: research
Neurological telerehabilitation in the COVID-19 era – current perspectives through a bibliometric analysis
ConclusionA greater interest in the subject was observed in China with greater relevance of journals and institutions focused on neurology. However, despite telerehabilitation being an effective alternative in the context of the pandemic, few studies have explored this modality.
Source: Frontiers in Neurology - September 19, 2023 Category: Neurology Source Type: research
The necessity of proactive measures from healthcare providers highlighted by delayed breast cancer diagnosis due to COVID-19: A case report
Clin Case Rep. 2023 Sep 15;11(9):e7919. doi: 10.1002/ccr3.7919. eCollection 2023 Sep.ABSTRACTKEY CLINICAL MESSAGE: During disasters, multiple factors can cause significant delays in medical visits. Regular patient monitoring, high-risk individual alerts, and telemedicine enhancements can potentially alleviate these issues and ensure timely interventions.ABSTRACT: During the COVID-19 pandemic, a Japanese woman in her 70s delayed her regular breast cancer checkup for over 2 years. During disasters, health priorities tend to decline, necessitating proactive measures from healthcare providers, such as augmenting collaboration ...
Source: Clinical Breast Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Yudai Kaneda Akihiko Ozaki Mira Namba Toyoaki Sawano Masahiro Wada Hiroaki Saito Yoshiaki Kanemoto Tomohiro Kurokawa Masaharu Tsubokura Kazunoshin Tachibana Tetsuya Tanimoto Tohru Ohtake Tomozo Ejiri Hiroaki Shimmura Norio Kanzaki Source Type: research
NewsCap: WHO: COVID-19 death toll is greater than previously reported
Am J Nurs. 2022 Sep 1;122(9):18. doi: 10.1097/01.NAJ.0000874084.43391.5f.NO ABSTRACTPMID:37718985 | DOI:10.1097/01.NAJ.0000874084.43391.5f
Source: The American Journal of Nursing - September 18, 2023 Category: Nursing Source Type: research
Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study
CONCLUSION: Pandemic-associated restrictions led to fewer primary care consultations and relative increases in analgesic prescribing, including strong opioids, for RMDs in the UK. Policymakers must consider the impact of these changes in future healthcare resource planning.PMID:37722859 | DOI:10.3399/BJGP.2022.0648
Source: The British Journal of General Practice - September 18, 2023 Category: Primary Care Authors: Victoria K Welsh Kayleigh J Mason James Bailey Ram Bajpai Kelvin P Jordan Christian D Mallen Claire Burton Source Type: research
NewsCAP: Drug-resistant infections skyrocketed in 2020, mainly due to effects of COVID-19
Am J Nurs. 2022 Nov 1;122(11):13. doi: 10.1097/01.NAJ.0000897080.40122.af.NO ABSTRACTPMID:37718922 | DOI:10.1097/01.NAJ.0000897080.40122.af
Source: The American Journal of Nursing - September 18, 2023 Category: Nursing Source Type: research
ASO Visual Abstract: COVID-19 Pandemic Did Not Influence the Number of Oncologic and Emergency Surgeries-A Retrospective Cohort Study from a Tertiary Hospital in Austria
Ann Surg Oncol. 2023 Sep 18. doi: 10.1245/s10434-023-14330-5. Online ahead of print.NO ABSTRACTPMID:37721692 | DOI:10.1245/s10434-023-14330-5
Source: Ann Oncol - September 18, 2023 Category: Cancer & Oncology Authors: Lukas Gasteiger Gabriel Putzer Elisabeth Hoerner Michael Joannidis Timo Mayerhoefer Tobias Hell Ottokar Stundner Judith Martini Source Type: research
Social Isolation of Older Adults, Family, and Formal Caregivers During the COVID-19 Pandemic: Stories and Solutions Through Participatory Action Research
Can J Aging. 2023 Sep 18:1-14. doi: 10.1017/S071498082300048X. Online ahead of print.ABSTRACTThis participatory action research (PAR) aimed to understand the health implications of guidelines impacting social isolation among frail community-dwelling older adults and their family and formal caregivers during the coronavirus disease (COVID-19) pandemic. Reflexive thematic analysis (RTA) of data collected from 10 policy/procedural documents revealed four themes: valuing principles, identifying problem(s), setting priorities, and making recommendations. Interviews with 31 participants from Peterborough, Ontario, also revealed ...
Source: Canadian Journal on Aging - September 18, 2023 Category: Geriatrics Authors: Ann MacLeod Justine Levesque Catherine Ward-Griffin Source Type: research
Registered Practical Nurses' Experiences of the Moral Habitability of Long-Term Care Environments during the COVID-19 Pandemic
Can J Aging. 2023 Sep 18:1-9. doi: 10.1017/S0714980823000491. Online ahead of print.ABSTRACTThe COVID-19 pandemic has had a deleterious impact on the lives of nurses who work in long-term care; however, the moral conditions of their work have been largely unexamined. The purpose of this qualitative study, therefore, was to explore registered practical nurses' (RPNs) experiences of the moral habitability of long-term care environments in Ontario, Canada during the COVID-19 pandemic. Four themes were identified: (1) Striving to meet responsibilities in a failed system; (2) bearing the moral and emotional weight of residents'...
Source: Canadian Journal on Aging - September 18, 2023 Category: Geriatrics Authors: Elizabeth Peter Shan Mohammed Priscilla Boakye Donald Rose Tieghan Killackey Source Type: research
The necessity of proactive measures from healthcare providers highlighted by delayed breast cancer diagnosis due to COVID-19: A case report
Clin Case Rep. 2023 Sep 15;11(9):e7919. doi: 10.1002/ccr3.7919. eCollection 2023 Sep.ABSTRACTKEY CLINICAL MESSAGE: During disasters, multiple factors can cause significant delays in medical visits. Regular patient monitoring, high-risk individual alerts, and telemedicine enhancements can potentially alleviate these issues and ensure timely interventions.ABSTRACT: During the COVID-19 pandemic, a Japanese woman in her 70s delayed her regular breast cancer checkup for over 2 years. During disasters, health priorities tend to decline, necessitating proactive measures from healthcare providers, such as augmenting collaboration ...
Source: Clinical Genitourinary Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Yudai Kaneda Akihiko Ozaki Mira Namba Toyoaki Sawano Masahiro Wada Hiroaki Saito Yoshiaki Kanemoto Tomohiro Kurokawa Masaharu Tsubokura Kazunoshin Tachibana Tetsuya Tanimoto Tohru Ohtake Tomozo Ejiri Hiroaki Shimmura Norio Kanzaki Source Type: research
Emergency department visits and hospital admissions for suicidal ideation, self-poisoning and self-harm among adolescents in Canada during the COVID-19 pandemic
CMAJ. 2023 Sep 18;195(36):E1221-E1230. doi: 10.1503/cmaj.220507.ABSTRACTBACKGROUND: The COVID-19 pandemic had profound effects on the mental wellbeing of adolescents. We sought to evaluate pandemic-related changes in health care use for suicidal ideation, self-poisoning and self-harm.METHODS: We obtained data from the Canadian Institute for Health Information on emergency department visits and hospital admissions from April 2015 to March 2022 among adolescents aged 10-18 years in Canada. We calculated the quarterly percentage of emergency department visits and hospital admissions for a composite outcome comprising suicidal...
Source: cmaj - September 18, 2023 Category: General Medicine Authors: Naveen Poonai Stephen B Freedman Amanda S Newton Scott Sawyer Nathalie Gaucher Samina Ali Bruce Wright Michael R Miller Ahmed Mater Eleanor Fitzpatrick Mona Jabbour Roger Zemek Mohamed Eltorki Quynh Doan Pediatric Emergency Research Canada (PERC) Network Source Type: research
Self-harm among youth during the first 28 months of the COVID-19 pandemic in Ontario, Canada: a population-based study
We reported relative differences between observed and expected monthly rates overall and by age group (10-13 yr and 14-17 yr), sex and mental health service use (new and continuing).RESULTS: In this population of about 1.3 million children and adolescents, rates of acute care visits for self-harm during the pandemic were higher than expected for emergency department visits (0.27/1000 population v. 0.21/1000 population; adjusted rate ratio [RR] 1.29, 95% confidence interval [CI] 1.19-1.39) and hospital admissions (0.74/10 000 population v. 0.43/10 000 population, adjusted RR 1.72, 95% CI 1.46-2.03). This increase was primar...
Source: cmaj - September 18, 2023 Category: General Medicine Authors: Rachel H B Mitchell Alene Toulany Hannah Chung Eyal Cohen Longdi Fu Rachel Strauss Simone N Vigod Therese A Stukel Kimberly Moran Astrid Guttmann Paul Kurdyak Azmina Artani Monica Kopec Natasha R Saunders Source Type: research
