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Cancer: Squamous Cell Carcinoma
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Total 19037 results found since Jan 2013.
Development and Validation of the Oxidative Stress Related lncRNAs for Prognosis in Esophageal Squamous Cell Carcinoma
In conclusion, our study demonstrated that a novel oxidative stress-related DElncRNA prognostic model performed favorably in predicting ESCC patient prognosis and benefits personalized clinical applications.PMID:37686677 | DOI:10.3390/cancers15174399
Source: Cancer Control - September 9, 2023 Category: Cancer & Oncology Authors: Xuan Zheng Wei Liu Yingze Zhu Wenyue Kong Xin Su Lanxiang Huang Yishuang Cui Guogui Sun Source Type: research
The impact of transformation zone representation on the frequency of abnormal cervical cytological results
CONCLUSION: Samples with TZ representation were associated with higher rates of abnormal results. Health professionals should be regularly trained to understand the weakness of cytological examinations when the TZ is not represented, especially in developing countries.PMID:37688813 | DOI:10.1016/j.ejogrb.2023.08.394
Source: Reproductive Biology - September 9, 2023 Category: Reproduction Medicine Authors: Renata Alfena Zago Deolino Jo ão Camilo-Júnior Solange Correa Garcia Pires D' Ávilla Jos é Cândido Caldeira Xavier-Júnior Source Type: research
Machine-Learning-Aided Prediction of Brain Metastases Development in Non-Small-Cell Lung Cancers
CONCLUSION: Analysis of the importance of input features suggests that the models are learning the relevant relationships between clinical features/development of BM. A higher number of samples is to be prioritized to improve performance. Employed prospectively at initial diagnosis, such models can help select high-risk subgroups for surveillance brain MRI.PMID:37689579 | DOI:10.1016/j.cllc.2023.08.002
Source: Clinical Lung Cancer - September 9, 2023 Category: Cancer & Oncology Authors: Giovanni Vison à Lisa M Spiller Sophia Hahn Elke Hattingen Thomas J Vogl Gabriele Schweikert Katrin Bankov Melanie Demes Henning Reis Peter Wild Pia S Zeiner Fabian Acker Martin Sebastian Katharina J Wenger Source Type: research
The prognostic value of lymphatic metastatic size in head and neck squamous cell carcinoma
CONCLUSIONS: Lymphatic metastatic size was an independently prognostic factor in HNSCC, which may assist in postoperative adjuvant treatment decisions.PMID:37682351 | DOI:10.1007/s00405-023-08199-z
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Wenqian Xie Peiliang Lin Zhijuan Li Huan Wan Faya Liang Jianming Fan Lanlan Deng Xiaoming Huang Source Type: research
Clinicopathologic study of stage I adenosquamous carcinoma of the lung
CONCLUSIONS: Early-stage adenosquamous carcinoma of the lung is a histological type associated with severe prognosis and postoperative recurrence, often in distant sites, in approximately one-third of cases. High serum carcinoembryonic antigen levels and vascular invasion might be risk factors of recurrence.PMID:37681230 | DOI:10.1093/jjco/hyad122
Source: Clinical Lung Cancer - September 8, 2023 Category: Cancer & Oncology Authors: Yoshinori Handa Takuhiro Ikeda Hideaki Hanaki Yoshihiro Miyata Hidenori Mukaida Morihito Okada Source Type: research
Prevalence of human papillomavirus infection in abnormal pap smears
CONCLUSION: Our study shows that the percentage of HR-HPV-positive case increases with the severity of cytologic morphology. HPV had 4 times higher positivity in squamous intraepithelial lesion as compared to ASCUS.PMID:37681080 | PMC:PMC10481853 | DOI:10.25259/Cytojournal_8_2021
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Jaya Mishra Sweety Kalantri Vandana Raphael Biswajit Dey Yookarin Khonglah Ananya Das Source Type: research
Importance of tumor volume, overall treatment time and fractionation sensitivity for p16-positive and p16-negative oropharyngeal tumors
CONCLUSION: Primary tumor volume plays a crucial role in predicting local tumor response, particularly in p16-positive OPSCC. The estimated α/β-ratio for p16-positive oropharyngeal tumors aligns with previous HNSCC studies, whereas the impact of prolonged OTT was slightly less than previously reported. The differences in radiosensitivity depending on p16-status were quantified. The findings should be validated in independent cohorts.PMID:37682690 | DOI:10.1080/0284186X.2023.2251084
Source: Acta Oncologica - September 8, 2023 Category: Cancer & Oncology Authors: Gabriel Adrian Maria Gebre-Medhin Per Nilsson Source Type: research
miR-200b-mediated reversion of a spectrum of epithelial to mesenchymal transition states in recessive dystrophic epidermolysis bullosa squamous cell carcinomas
CONCLUSIONS: In summary, RDEB-SCCs exist in different EMT states and the level of miR-200b is indicative of how far an RDEB-SCC has gone down the EMT path. Moreover, reintroduction of miR-200b significantly reduced mesenchymal features.PMID:37681509 | DOI:10.1093/bjd/ljad335
Source: The British Journal of Dermatology - September 8, 2023 Category: Dermatology Authors: Julia Illmer Roland Zauner Josefina Pi ñón Hofbauer Monika Wimmer Stefanie Gruner Michael Ablinger Johannes Bischof Sonja Dorfer Stefan Hainzl Vanessa Tober Shir Bergson Ofer Sarig Liat Samuelov Christina Guttmann-Gruber Ruby Shalom-Feuerstein Eli Sprec Source Type: research
A Novel Saliva and Serum miRNA Panel as a potential useful index for Oral Cancer and the Association of miR-21 with smoking history: a pilot study
Cancer Prev Res (Phila). 2023 Sep 8. doi: 10.1158/1940-6207.CAPR-23-0219. Online ahead of print.ABSTRACTTobacco use is implicated in the carcinogenesis of oral squamous cell carcinoma (OSCC), which is associated with poor survival if not diagnosed early. Identification of novel non-invasive, highly sensitive, and cost-effective diagnostic and risk assessment methods for OSCC would improve early detection. Here, we report a pilot study assessing salivary and serum miRNAs associated with OSCC and stratified by smoking status. Saliva and paired serum samples were collected from 23 OSCC patients and 21 healthy volunteers, with...
Source: Cell Research - September 8, 2023 Category: Cytology Authors: Dimitra P Vageli Panagiotis G Doukas Rema Shah Trinithas Boyi Christina Liu Benjamin L Judson Source Type: research
Clinicopathologic study of stage I adenosquamous carcinoma of the lung
CONCLUSIONS: Early-stage adenosquamous carcinoma of the lung is a histological type associated with severe prognosis and postoperative recurrence, often in distant sites, in approximately one-third of cases. High serum carcinoembryonic antigen levels and vascular invasion might be risk factors of recurrence.PMID:37681230 | DOI:10.1093/jjco/hyad122
Source: Clinical Lung Cancer - September 8, 2023 Category: Cancer & Oncology Authors: Yoshinori Handa Takuhiro Ikeda Hideaki Hanaki Yoshihiro Miyata Hidenori Mukaida Morihito Okada Source Type: research
Clinical Relevance of Patient-Derived Organoid of Surgically Resected Lung Cancer as an In Vitro Model for Biomarker and Drug Testing
CONCLUSIONS: The establishment and growth rates of LTOs were associated with the histologic subtype and tumor size. LTOs derived from resected specimens have become preclinical models that can be used to predict drug responses and accelerate the development of treatment strategies for patients with rare mutations.PMID:37681218 | PMC:PMC10480534 | DOI:10.1016/j.jtocrr.2023.100554
Source: Clinical Lung Cancer - September 8, 2023 Category: Cancer & Oncology Authors: Takamasa Koga Junichi Soh Akira Hamada Yuki Miyano Toshio Fujino Keiko Obata Shuta Ohara Masaya Nishino Masato Chiba Masaki Shimoji Toshiki Takemoto Kenichi Suda Kazuko Sakai Hidenori Sato Tetsuya Mitsudomi Source Type: research
Involvement of CHRNA6 in the Immune Response in Lung Squamous Cell Carcinoma and its Potential as a Drug Target for the Disease
CONCLUSION: CHRNA6 may be associated with immune infiltration in LUSC and affects patient prognosis and immunotherapeutic response by regulating immune cells and immune pathways. In addition, adavosertib may be a potential drug for the treatment of LUSC.PMID:37680128 | DOI:10.2174/1381612829666230901143203
Source: Current Pharmaceutical Design - September 8, 2023 Category: Drugs & Pharmacology Authors: Fengyu Zhang Meidi Zhang Xin Yuan Yulian Tao Ju Wang Source Type: research
Clinical Relevance of Patient-Derived Organoid of Surgically Resected Lung Cancer as an In Vitro Model for Biomarker and Drug Testing
CONCLUSIONS: The establishment and growth rates of LTOs were associated with the histologic subtype and tumor size. LTOs derived from resected specimens have become preclinical models that can be used to predict drug responses and accelerate the development of treatment strategies for patients with rare mutations.PMID:37681218 | PMC:PMC10480534 | DOI:10.1016/j.jtocrr.2023.100554
Source: Cell Research - September 8, 2023 Category: Cytology Authors: Takamasa Koga Junichi Soh Akira Hamada Yuki Miyano Toshio Fujino Keiko Obata Shuta Ohara Masaya Nishino Masato Chiba Masaki Shimoji Toshiki Takemoto Kenichi Suda Kazuko Sakai Hidenori Sato Tetsuya Mitsudomi Source Type: research
