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Cancer: Squamous Cell Carcinoma

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Total 19037 results found since Jan 2013.

Poly(A)-specific ribonuclease protein promotes the proliferation, invasion and migration of esophageal cancer cells
CONCLUSION: PARN has antiapoptotic effects on EC cells and promotes their proliferation, invasion and migration, which is associated with the development of EC and poor patient prognosis. PARN may become a potential target for the diagnosis, prognosis prediction and treatment of EC.PMID:37664151 | PMC:PMC10473923 | DOI:10.3748/wjg.v29.i31.4783
Source: World Journal of Gastroenterology : WJG - September 4, 2023 Category: Gastroenterology Authors: Fu-Wei Zhang Xiao-Wei Xie Meng-Hua Chen Jian Tong Qun-Qing Chen Jing Feng Feng-Ti Chen Wen-Qi Liu Source Type: research

Intralesional 5-fluorouracil as a management for cutaneous squamous cell carcinomas: A rural Australian retrospective case series
Australas J Dermatol. 2023 Sep 4. doi: 10.1111/ajd.14148. Online ahead of print.ABSTRACTWhile the gold standard treatment for cutaneous squamous cell carcinomas (cSCCs) is surgical removal, there is a risk of infection, cosmetic and functional deficits. Intralesional 5-fluorouracil (5-FU) has been shown to be a potential non-surgical treatment modality for cSCCs in the literature. The aim was to investigate the safety and feasibility of using intralesional 5-FU to treat cSCCs. A literature review was conducted and a retrospective case series analysed patients who commenced intralesional 5-FU treatment for at least one cSCC...
Source: The Australasian Journal of Dermatology - September 4, 2023 Category: Dermatology Authors: William Luu Michelle Yvonne McRae Source Type: research

Tumour budding in cutaneous squamous cell carcinoma: A novel prognosis risk factor
CONCLUSION: An association was found between tumour budding and most known risk factors in cSCC. We found findings that indicate that the presence of tumour budding is associated with a worse prognosis in terms of LNM, OS and DSS. This supports the results of previous work which has suggested that budding could be related to high-risk cSCC.PMID:37665122 | DOI:10.1111/ajd.14150
Source: The Australasian Journal of Dermatology - September 4, 2023 Category: Dermatology Authors: Loreto Heredia Pablo Vargas-Mora Catalina Jahr Jos é Herranz Pedro Ferrer-Rosende Source Type: research

Poly(A)-specific ribonuclease protein promotes the proliferation, invasion and migration of esophageal cancer cells
CONCLUSION: PARN has antiapoptotic effects on EC cells and promotes their proliferation, invasion and migration, which is associated with the development of EC and poor patient prognosis. PARN may become a potential target for the diagnosis, prognosis prediction and treatment of EC.PMID:37664151 | PMC:PMC10473923 | DOI:10.3748/wjg.v29.i31.4783
Source: World Journal of Gastroenterology : WJG - September 4, 2023 Category: Gastroenterology Authors: Fu-Wei Zhang Xiao-Wei Xie Meng-Hua Chen Jian Tong Qun-Qing Chen Jing Feng Feng-Ti Chen Wen-Qi Liu Source Type: research

DNA methylation of KIFC1 gene in determination of histological diagnosis, prognosis and metastasis of lung cancer
CONCLUSION: In conclusion, the increase in the expression level of the KIFC1 gene is higher in patients diagnosed with LC than in the healthy population, and therefore, the increase in the expression level of the KIFC1 gene due to hypomethylation can be used as a screening biomarker in LC. It can also be considered that the methylation profile of the KIFC1 gene may be a potential biomarker for determining the subtype of squamous cell carcinoma in LC. The results of the study need to be analyzed and continued with a larger number of patients.PMID:37666088 | DOI:10.1016/j.prp.2023.154742
Source: Pathology, Research and Practice - September 4, 2023 Category: Pathology Authors: Betul Celik Ozge Pasin Sena Sen Seref Bugra Tuncer Zubeyde Yaln ız Kayım Seda K ılıc Erciyas Ozge Sukruoglu Erdogan Busra Kurt Gultaslar Arash Adamnejad Ghafour Hulya Yaz ıcı Necat Vakur Olgac Source Type: research

Intralesional 5-fluorouracil as a management for cutaneous squamous cell carcinomas: A rural Australian retrospective case series
Australas J Dermatol. 2023 Sep 4. doi: 10.1111/ajd.14148. Online ahead of print.ABSTRACTWhile the gold standard treatment for cutaneous squamous cell carcinomas (cSCCs) is surgical removal, there is a risk of infection, cosmetic and functional deficits. Intralesional 5-fluorouracil (5-FU) has been shown to be a potential non-surgical treatment modality for cSCCs in the literature. The aim was to investigate the safety and feasibility of using intralesional 5-FU to treat cSCCs. A literature review was conducted and a retrospective case series analysed patients who commenced intralesional 5-FU treatment for at least one cSCC...
Source: The Australasian Journal of Dermatology - September 4, 2023 Category: Dermatology Authors: William Luu Michelle Yvonne McRae Source Type: research

Tumour budding in cutaneous squamous cell carcinoma: A novel prognosis risk factor
CONCLUSION: An association was found between tumour budding and most known risk factors in cSCC. We found findings that indicate that the presence of tumour budding is associated with a worse prognosis in terms of LNM, OS and DSS. This supports the results of previous work which has suggested that budding could be related to high-risk cSCC.PMID:37665122 | DOI:10.1111/ajd.14150
Source: The Australasian Journal of Dermatology - September 4, 2023 Category: Dermatology Authors: Loreto Heredia Pablo Vargas-Mora Catalina Jahr Jos é Herranz Pedro Ferrer-Rosende Source Type: research

Identification and validation of a prognostic signature of cuproptosis-related genes for esophageal squamous cell carcinoma
In this study, we observed significant expression differences in most of the 12 cuproptosis-related genes (CRGs) in the TCGA-ESCC dataset, which was validated using GSE20347, GSE38129, and individual ESCC datasets. We were able to divide patients in the TCGA-ESCC cohort into two subgroups based on disease, and found significant differences in survivor outcomes and biological functions between these subgroups. Additionally, we identified 11 prognosis-related genes from the 12 CRGs using LASSO COX regression analysis and constructed a CRGs signature for ESCC. Patients were categorized into high- and low-risk subgroups based ...
Source: Aging - September 4, 2023 Category: Biomedical Science Authors: Yiping Zhang Kebing Chen Liyan Wang Juhui Chen Zhizhong Lin Yuanmei Chen Junqiang Chen Yu Lin Yuanji Xu Haiyan Peng Source Type: research

Intralesional 5-fluorouracil as a management for cutaneous squamous cell carcinomas: A rural Australian retrospective case series
Australas J Dermatol. 2023 Sep 4. doi: 10.1111/ajd.14148. Online ahead of print.ABSTRACTWhile the gold standard treatment for cutaneous squamous cell carcinomas (cSCCs) is surgical removal, there is a risk of infection, cosmetic and functional deficits. Intralesional 5-fluorouracil (5-FU) has been shown to be a potential non-surgical treatment modality for cSCCs in the literature. The aim was to investigate the safety and feasibility of using intralesional 5-FU to treat cSCCs. A literature review was conducted and a retrospective case series analysed patients who commenced intralesional 5-FU treatment for at least one cSCC...
Source: The Australasian Journal of Dermatology - September 4, 2023 Category: Dermatology Authors: William Luu Michelle Yvonne McRae Source Type: research

Tumour budding in cutaneous squamous cell carcinoma: A novel prognosis risk factor
CONCLUSION: An association was found between tumour budding and most known risk factors in cSCC. We found findings that indicate that the presence of tumour budding is associated with a worse prognosis in terms of LNM, OS and DSS. This supports the results of previous work which has suggested that budding could be related to high-risk cSCC.PMID:37665122 | DOI:10.1111/ajd.14150
Source: The Australasian Journal of Dermatology - September 4, 2023 Category: Dermatology Authors: Loreto Heredia Pablo Vargas-Mora Catalina Jahr Jos é Herranz Pedro Ferrer-Rosende Source Type: research

A case of squamous cell carcinoma in situ of the cornea of the left eye
Asian J Surg. 2023 Sep 1:S1015-9584(23)01351-9. doi: 10.1016/j.asjsur.2023.08.192. Online ahead of print.NO ABSTRACTPMID:37661481 | DOI:10.1016/j.asjsur.2023.08.192
Source: Asian Journal of Surgery - September 4, 2023 Category: Surgery Authors: Shuang Rao Source Type: research

Poly(A)-specific ribonuclease protein promotes the proliferation, invasion and migration of esophageal cancer cells
CONCLUSION: PARN has antiapoptotic effects on EC cells and promotes their proliferation, invasion and migration, which is associated with the development of EC and poor patient prognosis. PARN may become a potential target for the diagnosis, prognosis prediction and treatment of EC.PMID:37664151 | PMC:PMC10473923 | DOI:10.3748/wjg.v29.i31.4783
Source: World Journal of Gastroenterology : WJG - September 4, 2023 Category: Gastroenterology Authors: Fu-Wei Zhang Xiao-Wei Xie Meng-Hua Chen Jian Tong Qun-Qing Chen Jing Feng Feng-Ti Chen Wen-Qi Liu Source Type: research