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Infectious Disease: Epidemics
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Total 343 results found since Jan 2013.
Epigenetics of Early-Life Socioeconomic Stressors and the Impact on Childhood Body Mass Index —Potential Mechanism and Biomarker?
Overweight and obesity are growing epidemics worldwide. Recent estimates from the World Health Organization indicate that 39% of adults had overweight, and 13% had obesity. In addition, an estimated 340 million children and adolescents aged 5 to 19 years had overweight or obesity in 2016 whereas 39 million children younger than 5 years had overweight or obesity in 2020. Understanding the biological mechanisms behind the development of overweight and obesity is critical as overweight and obesity are risk factors for a host of cardiometabolic outcomes including heart disease, stroke, diabetes, and chronic kidney disease. The...
Source: JAMA Pediatrics - September 5, 2023 Category: Pediatrics Source Type: research
Lower 25-hydroxyvitamin D is associated with severer white matter hyperintensity and cognitive function in patients with non-disabling ischemic cerebrovascular events
Vascular cognitive impairment (VCI) is the second most common type of cognitive impairment, referring to the entire spectrum of cognitive impairment contributed by cerebrovascular pathology1. Due to the progressively higher incidence of stroke and cerebrovascular diseases, VCI, including post-stroke cognitive impairment are the leading causes of disability epidemic worldwide2-3. White matter lesions, manifested as white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI) scans, are one of the most common pathological characteristics of VCI4.
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2023 Category: Neurology Authors: Zhengsheng Gu, Xu Sun, Chenghao Wu, Binghan Li, Jingjing Chen, Weisen Wang, Xin Gao, Yuhao Tan, Bin Li, Ge Yin, Yawen Xu, Chenrui Song, Bingying Du, Xiaoying Bi Source Type: research
Neurological manifestations of SARS-CoV-2: complexity, mechanism and associated disorders
CONCLUSIONS: SARS-CoV-2 can lead to neurological complications, such as cerebrovascular manifestations, motor movement complications, and cognitive decline. COVID-19 infection can result in cerebrovascular symptoms and diseases, such as strokes and thrombosis. The virus can affect the neural system, disrupt cognitive function and cause neurological disorders. To combat the epidemic, it is crucial to repurpose drugs currently in use quickly and develop novel therapeutics.PMID:37649125 | PMC:PMC10469568 | DOI:10.1186/s40001-023-01293-2
Source: Cell Research - August 30, 2023 Category: Cytology Authors: Kritika Tyagi Prachi Rai Anuj Gautam Harjeet Kaur Sumeet Kapoor Ashish Suttee Pradeep Kumar Jaiswal Akanksha Sharma Gurpal Singh Ravi Pratap Barnwal Source Type: research
Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on Emergency Patients Hospitalized With Cardiocerebrovascular Diseases in Osaka Prefecture, Japan - A Population-Based Study
CONCLUSIONS: The numbers of emergency patients hospitalized with cardiocerebrovascular diseases and their deaths in Osaka were not affected by the COVID-19 epidemic.PMID:37532531 | DOI:10.1253/circj.CJ-23-0298
Source: Circulation Journal - August 2, 2023 Category: Cardiology Authors: Kenta Tanaka Yusuke Katayama Tetsuhisa Kitamura Hisaya Dohmi Jun Masui Tomoya Hirose Shunichiro Nakao Jotaro Tachino Ling Zha Tomotaka Sobue Jun Oda Tetsuya Matsuoka Source Type: research
Atrial Cardiopathy: Redefining Stroke Risk Beyond Atrial Fibrillation
Atrial fibrillation (AF) and ischemic stroke are dual epidemics in society, both associated with poor clinical outcomes, patient disability, and significant healthcare expenditure. The conditions are interrelated and share complex causal pathways. Risk stratification algorithms such as the CHADS2 and CHA2DS2-VASc score offer predictive value in stroke and systemic embolism risk in the AF population, however, have limitations. Recent evidence suggests that an intrinsically prothrombotic atrial substrate may precede and promote AF and lead to thromboembolic events independent of the arrhythmia, allowing for a window of inter...
Source: The American Journal of Cardiology - June 28, 2023 Category: Cardiology Authors: Jessica Chu Zhang, Aditya Bhat Source Type: research
Less Sodium, More Potassium, or Both: Population-wide Strategies to Prevent Hypertension
Am J Physiol Renal Physiol. 2023 Jun 1. doi: 10.1152/ajprenal.00007.2023. Online ahead of print.ABSTRACTHypertension is among the most prevalent medical conditions globally and a major contributor to chronic kidney disease, cardiovascular disease, and death. Prevention through non-pharmacologic, population-level interventions is critically needed to halt this worldwide epidemic. However, there are ongoing debates as to where public policy efforts should focus. Recently the Salt Substitute and Stroke Study demonstrated the efficacy of substituting table salt with potassium salt to reduce the risk of stroke, major cardiovasc...
Source: Am J Physiol Renal P... - June 1, 2023 Category: Urology & Nephrology Authors: Voravech Nissaisorakarn George Ormseth William Earle Martha Catalina Morales-Alvarez Swapnil Hiremath Stephen P Juraschek Source Type: research
