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Infectious Disease: Epidemics

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Total 343 results found since Jan 2013.

Influence of coronavirus disease 2019 (COVID-19) on working flow, safety and efficacy outcome of mechanical thrombectomy for acute ischemic stroke with large vessel occlusion
CONCLUSIONS: Prolongation of the working time flow during the COVID-19 epidemic did not influence the safety and efficacy of EVT in AIS patients with LVO. However, special policy and particular measures in this circumstances is still need to evolve to improve the treatment quality.PMID:34000867 | DOI:10.1177/15910199211018093
Source: Interventional Neuroradiology - May 18, 2021 Category: Radiology Authors: Xiaochuan Huo Xuan Sun Dapeng Mo Feng Gao Ning Ma Yilong Wang Yongjun Wang Zhongrong Miao Source Type: research

Anesthetic management for robotic hysterectomy in obese women
Purpose of review Obesity is a major health epidemic, with the prevalence reaching ∼40% in the United States in recent years. It is associated with increased risk of hypertension, diabetes, heart disease, stroke, obstructive sleep apnea (OSA), and gynecologic conditions requiring surgery. Those comorbidities, in addition to the physiologic changes associated with obesity, lead to increased risk of perioperative complications. The purpose of this review is to highlight the anesthetic considerations for robotic assisted hysterectomy in obese patients. Recent findings In the general gynecologic population, minima...
Source: Current Opinion in Anaesthesiology - May 12, 2021 Category: Anesthesiology Tags: OBSTETRIC AND GYNECOLOGICAL ANESTHESIA: Edited by Jill Mhyre Source Type: research

Potential impact of gradual reduction of fat content in manufactured and out-of-home food on obesity in the United Kingdom: a modeling study
ConclusionsA modest fat reduction (particularly in SFA) in widely consumed foods would prevent obesity, type 2 diabetes, and cardiovascular disease.
Source: American Journal of Clinical Nutrition - May 8, 2021 Category: Nutrition Source Type: research

STratification risk analysis in OPerative management (STOP score) for drug ‐induced endocarditis
CONCLUSIONDrug ‐related IE is associated with significant morbidity and mortality. An easily‐applied risk stratification score may aid in clinical decision‐making.
Source: Journal of Cardiac Surgery - April 25, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Andreas Habertheuer, Arnar Geirsson, Thomas Gleason, Joseph Woo, Bryan Whitson, George J Arnaoutakis, Pavan Atluri, Arminder Jassar, Tsuyoshi Kaneko, Arman Kilic, Paul C Tang, Asher J. Schranz, Syed Usman Bin Mahmood, Makoto Mori, Ibrahim Su Tags: ORIGINAL ARTICLE Source Type: research

The emerging association between COVID-19 and acute stroke
Trends Neurosci. 2021 Apr 8:S0166-2236(21)00071-0. doi: 10.1016/j.tins.2021.03.005. Online ahead of print.ABSTRACTPrior to COVID-19, only two human-tropic coronaviruses resulted in epidemics and cerebrovascular disease was rarely reported. Evidence now suggests that 1-6% of hospitalized COVID-19 patients develop stroke. According to some reports, stroke risk is more than sevenfold greater in patients with COVID-19 than influenza. Concerningly, outcomes of COVID-19-related stroke are often worse than in stroke patients without COVID-19 from the same cohorts. In this review, we highlight the emerging association between COVI...
Source: Trends in Neurosciences - April 21, 2021 Category: Neuroscience Authors: Laura K Stein Naomi A Mayman Mandip S Dhamoon Johanna T Fifi Source Type: research

The hypothalamus for whole-body physiology: from metabolism to aging
Protein Cell. 2021 Apr 7. doi: 10.1007/s13238-021-00834-x. Online ahead of print.ABSTRACTObesity and aging are two important epidemic factors for metabolic syndrome and many other health issues, which contribute to devastating diseases such as cardiovascular diseases, stroke and cancers. The brain plays a central role in controlling metabolic physiology in that it integrates information from other metabolic organs, sends regulatory projections and orchestrates the whole-body function. Emerging studies suggest that brain dysfunction in sensing various internal cues or processing external cues may have profound effects on me...
Source: Protein and Cell - April 7, 2021 Category: Cytology Authors: Tiemin Liu Yong Xu Chun-Xia Yi Qingchun Tong Dongsheng Cai Source Type: research

Anti-diabetic drugs for preventing atrial fibrillation: a new revolution?
Type 2 diabetes mellitus (DM) and atrial fibrillation (AF) are two of the great epidemics of our time. DM affects and estimated 8.5% of adults in the US1, and is associated with an increased risk of cardiovascular events, including AF.2 AF in turn affects an estimated up to 12.5% of adults over age 65 years in the US, decreases quality of life and increases the risks of heart failure, stroke and death 3,4. In 2015, the EMPA-REG OUTCOME randomized controlled trial (RCT), assessing a sodium glucose co-transporter 2 inhibitor (SGLT-2i), sparked interest in the therapeutic potential for oral anti-diabetic agents to reduce card...
Source: Heart Rhythm - April 7, 2021 Category: Cardiology Authors: William F. McIntyre, Jeff S. Healey Source Type: research

Antidiabetic drugs for preventing atrial fibrillation: A new revolution?
Type 2 diabetes mellitus (DM) and atrial fibrillation (AF) are 2 of the great epidemics of our time. DM affects an estimated 8.5% of adults in the United States1 and is associated with an increased risk of cardiovascular events, including AF.2 AF in turn affects up to an estimated 12.5% of adults older than 65 years in the United States, decreases quality of life, and increases the risks of heart failure, stroke, and death.3,4 In 2015, the EMPA-REG OUTCOME (BI 10773 [Empagliflozin] Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients) randomized controlled trial (RCT), which assessed the sodium glucose c...
Source: Heart Rhythm - April 7, 2021 Category: Cardiology Authors: William F. McIntyre, Jeff S. Healey Tags: Editorial Commentary Source Type: research

Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic?
Circ Res. 2021 Apr 2;128(7):908-933. doi: 10.1161/CIRCRESAHA.121.318052. Epub 2021 Apr 1.ABSTRACTElevated cardiovascular risk including stroke, heart failure, and heart attack is present even after normalization of blood pressure in patients with hypertension. Underlying immune cell activation is a likely culprit. Although immune cells are important for protection against invading pathogens, their chronic overactivation may lead to tissue damage and high blood pressure. Triggers that may initiate immune activation include viral infections, autoimmunity, and lifestyle factors such as excess dietary salt. These conditions ac...
Source: Circulation Research - April 1, 2021 Category: Cardiology Authors: Meena S Madhur Fernando Elijovich Matthew R Alexander Ashley Pitzer Jeanne Ishimwe Justin P Van Beusecum David M Patrick Charles D Smart Thomas R Kleyman Justin Kingery Robert N Peck Cheryl L Laffer Annet Kirabo Source Type: research