Filtered By:
Therapy: Corticosteroid Therapy

This page shows you your search results in order of date. This is page number 18.

Order by Relevance | Date

Total 342 results found since Jan 2013.

Treatment of pediatric cerebral radiation necrosis: a systematic review
Abstract Cerebral radiation necrosis (CRN) is a toxicity of radiation therapy that can result in significant, potentially life-threatening neurologic deficits. Treatment for CRN has included surgical resection, corticosteroids, hyperbaric oxygen therapy (HBOT), and bevacizumab, but no consensus approach has been identified. We reviewed the available literature to evaluate efficacy of treatment approaches. Using methods specified in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines when possible, we conducted searches of Ovid MEDLINE, Embase and Pubmed to identify studies re...
Source: Journal of Neuro-Oncology - July 19, 2016 Category: Cancer & Oncology Source Type: research

Can Quantitative Muscle Strength and Functional Motor Ability Differentiate the Influence of Age and Corticosteroids in Ambulatory Boys with Duchenne Muscular Dystrophy?
Conclusion The baseline data analysis of this natural history study indicates that the outcomes measures utilized in this study were sensitive to the age related differences in strength and motor function that are characteristic of disease progression boys with DMD; however treatment effects were less likely to be identified. These findings reflect the difficulty inherent in obtaining the statistical power needed to substantiate intervention efficacy in the small, heterogeneous samples sizes that are characteristic of DMD clinical studies. Isokinetic dynamometry revealed variability in the muscles affected, which has been ...
Source: PLOS Currents Muscular Dystrophy - July 8, 2016 Category: Neurology Authors: cbuckon Source Type: research

Lupus Damage and Waist Circumference as the Independent Risk Factors for Cardiovascular Disease in SLE Patients from Phramongkutklao Hospital.
CONCLUSION: Lupus damage, waist circumference more than 90 centimeters in male or more than 80 centimeters in female were the independent risk factors for CVD in SLE patients. PMID: 27276740 [PubMed - in process]
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - June 11, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

Isolated Central Nervous System Vasculitis as a Manifestation of Neurosarcoidosis
A 62-year-old male presented to our clinic with recurrent fever, skin lesions (petechiae), scleral wounds, and hilar adenomegaly. A diagnosis of sarcoidosis was established, which resolved with corticosteroid treatment. After a few months, the patient developed confusion and behavioral changes, with few objective neurological deficits. Brain magnetic resonance imaging showed slight focal meningeal enhancement (prepontine region). The level of angiotensin-converting enzymes was normal in the serum and increased in the cerebrospinal fluid.
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2016 Category: Neurology Authors: Philippe Joaquim Oliveira Menezes Macêdo, Victor Calil da Silveira, Luíza Tavares Ramos, Felipe Resende Nóbrega, Luiz Felipe Rocha Vasconcellos Tags: Case Studies Source Type: research

The Effects of High Dose Corticosteroids for MS Relapse on Blood Pressure: A Pilot Study (P2.089)
Conclusions: MS patients treated with high dose CR for relapses lose the expected nighttime diastolic BP decrease. Further, those with a history or family history of HTN show a significant increase in systolic BP. Loss of nocturnal dip correlates with a significant increase in stroke risk. This pilot data suggests high dose CR treatment for MS relapses may have implications for cerebrovascular and cardiovascular health.Disclosure: Dr. Renn has nothing to disclose. Dr. Dresser has nothing to disclose. Dr. Morrow has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Renn, R., Dresser, G., Morrow, S. Tags: MS and CNS Inflammatory Disease: Treatment, Safety, and Tolerance Source Type: research

Multifocal Micro-Embolic Infarcts in Hypereosinophilic Syndrome: A Case Report (P4.350)
Conclusions: Hypereosinophilic syndromes can be a rare cause of stroke and should be considered especially in those with undetermined stroke mechanisms. HES is potentially treatable and can have a good prognosis but requires timely recognition and a thoughtful approach of potential underlying causes.Disclosure: Dr. Nguyen has nothing to disclose. Dr. Vanden Driessche has nothing to disclose. Dr. Hajek has nothing to disclose. Dr. Chen has nothing to disclose. Dr. Wilson has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Nguyen, A., Vanden Driessche, K., Hajek, J., Chen, L., Wilson, L. Tags: Cerebrovascular Case Reports Source Type: research

Neutrophils/Lymphocytes Ratio and Platelets/Lymphocytes Ratio and Its Relationship with Severity and Functional Prognosis in Patients with Acute Ischemic Stroke (P5.235)
CONCLUSIONS N/L ratio and P/L ratio at hospital admission have a positive correlation with the severity and functional prognosis of patients with Acute Ischemic Stroke. Due to its simple determination, affordable and safe, they could become severity and functional prognostic parameters in the initial evaluation of patients with Acute Ischemic Stroke in the future.Disclosure: Dr. Perez has nothing to disclose. Dr. Casas has nothing to disclose. Dr. Tourreilles has nothing to disclose. Dr. Gonzalez has nothing to disclose. Dr. Gimenez has nothing to disclose. Dr. Cabrera has nothing to disclose. Dr. Mattiazzi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Perez, A., Casas, S., Tourreilles, M., Gonzalez, C., Gimenez, J., Cabrera, L., Mattiazzi, M. Tags: Cerebrovascular Disease: Biomarkers Source Type: research

Ultrasound-guided corticosteroid injections for adhesive capsulitis more effective than placebo
Commentary on: Prestgaard T, Wormgoor ME, Haugen S, et al.. Ultrasound-guided intra-articular and rotator interval corticosteroid injections in adhesive capsulitis of the shoulder: a double-blind, sham-controlled randomized study. Pain 2015;156:1683–91. Context Adhesive capsulitis (frozen shoulder or painful stiff shoulder) is relatively common. It is idiopathic: known associated factors include trauma, diabetes, prolonged immobilisation, age, stroke and autoimmune disease. While self-limited, pain and decreased range of motion can last up to 2–3 years. Therefore, there is practical value in therapeutic in...
Source: Evidence-Based Medicine - March 21, 2016 Category: Internal Medicine Authors: Lebrun, C. M. Tags: Rehabilitation medicine, Immunology (including allergy), Pain (neurology), Stroke, Radiology, Degenerative joint disease, Musculoskeletal syndromes, Osteoarthritis, Sports and exercise medicine, Clinical diagnostic tests, Radiology (diagnostics), Screenin Source Type: research

Management of postoperative atrial fibrillation after cardiac surgery
This article will review the available evidence on the prevention and treatment of atrial fibrillation after cardiac surgery. Using this knowledge, we propose a conceptual framework on the management of patients with POAF during various phases after cardiac surgery. Recent findings: Perioperative β-blockade is the cornerstone in preventing POAF after cardiac surgery. Results from randomized trials do not support routine use of colchicine or corticosteroids to prevent POAF. There is no study examining the impact of rate versus rhythm control on ‘hard’ clinical outcomes such as mortality or stroke in the cardiac surgic...
Source: Current Opinion in Cardiology - February 5, 2016 Category: Cardiology Tags: VALVULAR HEART DISEASE: Edited by Subodh Verma Source Type: research

The Biggest Medical Stories You May Have Missed In 2015
SPECIAL FROM Next Avenue By Craig Bowron As we head into the New Year, let’s take a look back and see what lessons we should have learned from medical science in 2015. The New England Journal of Medicine’s publication Journal Watch provides physicians and other health care providers with expert analysis of the most recent medical research. Below is a brief synopsis of what the Journal Watch editors felt were the most important stories in general medicine for the year 2015. While you likely heard about a couple, others probably escaped your radar. Getting Aggressive with Strokes We’re familiar with the id...
Source: Science - The Huffington Post - January 15, 2016 Category: Science Source Type: news

Developments in Varicella Zoster Virus Vasculopathy
Abstract Varicella zoster virus (VZV) is a highly neurotropic human herpesvirus. Primary infection usually causes varicella (chicken pox), after which virus becomes latent in ganglionic neurons along the entire neuraxis. VZV reactivation results in zoster (shingles) which is frequently complicated by chronic pain (postherpetic neuralgia). VZV reactivation also causes meningoencephalitis, myelitis, ocular disorders, and vasculopathy, all of which can occur in the absence of rash. This review focuses on the association of VZV and stroke, and on the widening spectrum of disorders produced by VZV vasculopathy in immu...
Source: Current Neurology and Neuroscience Reports - January 11, 2016 Category: Neuroscience Source Type: research

Cerebral Venous Thromboembolism in Antiphospholipid Syndrome Successfully Treated with the Combined Use of an Anti-Xa Inhibitor and Corticosteroid.
Authors: Sugie M, Iizuka N, Shimizu Y, Ichikawa H Abstract We herein report a case presenting with cerebral venous sinus thrombosis (CVST) associated with primary antiphospholipid syndrome (APS). The patient developed recurrent CVST followed by a hemorrhagic ischemic stroke despite the use of warfarin during the appropriate therapeutic window. Thus, we substituted warfarin to rivaroxaban with prednisolone and obtained a good clinical course. In addition to the effect of prednisolone of inhibiting elevated lupus anticoagulants and the recurrence of arterial thrombosis, rivaroxaban may prevent CVST and inhibit hyperc...
Source: Internal Medicine - December 6, 2015 Category: Internal Medicine Tags: Intern Med Source Type: research

Fungal Infections of the Central Nervous System
This article summarizes current knowledge on the epidemiology, clinical presentations, diagnosis, and management of selected fungal infections of the central nervous system (CNS). Key syndromes, differential diagnoses, and therapeutic interventions according to host immune status and exposure are reviewed. Recent Findings:: Advancements in imaging of the brain and spinal cord, and molecular DNA and antigen-based laboratory diagnostics afford improved sensitivity for CNS mycoses. Newer therapeutic strategies may improve outcomes if provided early and host immunosuppression is abrogated. Adjunctive corticosteroid use for dis...
Source: CONTINUUM - December 1, 2015 Category: Neurology Tags: Review Articles Source Type: research

Cervical aspergillosis with dissemination to the central nervous system: Case reports and review of the literature.
CONCLUSION: IA must be considered a possibility whenever an immunocompromised patient presents with a new brain lesion. These lesions require surgical evacuation, a procedure that allows for diagnostic confirmation and enhances prognosis. Appropriate anti-fungal therapy must be started as soon as the diagnosis is confirmed. In addition, the patient's neurological exam must be repeated and images obtained periodically to monitor treatment and detect possible recurrences. PMID: 26600985 [PubMed - as supplied by publisher]
Source: Surgical Neurology International - November 25, 2015 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

Gout: Sleep apnea may raise your risk
Gout is the most common type of inflammatory arthritis and affects more than 8 million adults. Men are at a higher risk than women. And according to a new study, your risk for gout also climbs if you suffer from sleep apnea, a condition where your breathing repeatedly pauses while you sleep. What exactly is gout? Gout is triggered by the crystallization of uric acid within the joints. It happens like this: Your body produces uric acid from breaking down purines, a natural waste product of living cells. Normally, uric acid is dissolved in your blood and passes through your kidneys into your urine. However, sometimes your bo...
Source: New Harvard Health Information - November 17, 2015 Category: Consumer Health News Authors: Matthew Solan Tags: Arthritis Health Sleep gout sleep apnea Source Type: news