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Specialty: Cardiology
Nutrition: Calcium

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Total 207 results found since Jan 2013.

Prognostic value of coronary artery disease-reporting and data system (CAD-RADS) score for cardiovascular events in ischemic stroke
The coronary artery disease-reporting and data system (CAD-RADS) was recently developed to standardize CAD classifications and incorporate clinical management. We aimed to investigate the prognostic value and additional risk stratification benefits of the CAD-RADS compared to coronary artery calcium scores (CACS) and CAD extent classifications in ischemic stroke patients without cardiac symptoms.
Source: Atherosclerosis - May 26, 2019 Category: Cardiology Authors: Kyungsun Nam, Jin Hur, Kyunghwa Han, Dong Jin Im, Young Joo Suh, Yoo Jin Hong, Hye-Jeong Lee, Young Jin Kim, Byoung Wook Choi Source Type: research

Virtual histology-intravascular ultrasound as a diagnostic alternative for morphological characterization of carotid plaque: comparison with histology and high-resolution magnetic resonance findings
Conclusion We believe that VH-IVUS may be useful when a quick intraprocedural evaluation of a carotid plaque before or after stent placement is required, but is not suitable for the accurate in-vivo differentiation between stable and unstable plaques prone to rupture, due to the suboptimal assessment of the necrotic component, fibrous cap thickness and rupture signs. We do believe, however, that these results need further evaluation in larger populations to be confirmed.
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research

Coronary artery calcium score to guide hypertension therapy!
Hypertension is the most prevalent non-communicable disease, estimated to affect 1.13 billion individuals nowadays. It is the leading preventable cause of mortality worldwide and a major risk factor for coronary artery disease, heart failure, stroke and chronic renal diseases in developed and developing countries.1,2. Worldwide, the aging population, decreased fitness and obesity epidemic have contributed to the increased prevalence of hypertension3. Given that, it poses a significant health and economic challenge to both developed and developing countries.
Source: Atherosclerosis - January 25, 2019 Category: Cardiology Authors: Ahmed Aljizeeri, Ahmed Alsaileek, Mouaz H. Al-Mallah Tags: Editorial Source Type: research

Assessment of Non-vitamin K Oral Anticoagulants Use in a Tertiary Care Center in the USA: A Chart Review of 909 Patients
ConclusionA significant number of patients received NOACs at doses inconsistent with the package labeling or had clinically significant drug –drug interactions with NOACs. Efforts are warranted to improve appropriate dosing and avoid significant drug interactions.
Source: American Journal of Cardiovascular Drugs - November 8, 2018 Category: Cardiology Source Type: research

Usefulness of the Echocardiographic Calcium Score to Refine Risk of Major Adverse Cardiovascular Events Beyond the Traditional Framingham Risk Score
Echocardiographic calcifications are associated with major adverse cardiovascular events (MACE). A recently described semi-quantitative Global Cardiac Calcium Score (GCCS) has been associated with mortality and stroke, with increasing scores associated with increasing risk. This score assigns points for calcium in the aortic root and valve, mitral valve and annulus, and submitral apparatus, with additional points for restricted leaflet mobility. We tested the hypothesis that the GCCS could improve prediction of MACE beyond traditional risk scores.
Source: The American Journal of Cardiology - October 18, 2018 Category: Cardiology Authors: Parasuram Krishnamoorthy, Shuchita Gupta, Marvin Lu, Evan J. Friend, Gregg S. Pressman Source Type: research

Outcomes with a latest generation self-expandable, intra-annular, re-sheathable transcatheter heart valve system: analysis of patients with impaired left ventricular function and determinants for pacemaker implantation
ConclusionsThe Portico valve demonstrates a satisfying safety outcome, especially for patients with impaired LV function. Results of the CE-mark trial were confirmed, except for higher PPM rates. PPM rates are in accordance with other reports on this TAVI platform.
Source: Clinical Research in Cardiology - October 1, 2018 Category: Cardiology Source Type: research

Sex-mediated response to landiolol, a ß1 selectif adrenergic blocker, in myocardial dysfunction during sepsis
ConclusionLandiolol improved the in vivo cardiac performance of septic male rats, in association with an improvement in diastolic function. However, in septic females, treatment with landiolol resulted in deleterious effects. Ongoing analysis of these signaling pathways will aid better understanding of sex differences occurring in sepsis.
Source: Archives of Cardiovascular Diseases Supplements - July 10, 2018 Category: Cardiology Source Type: research

Impact of the Coronary Artery Calcium Score on Mid- to Long-Term Cardiovascular Mortality and Morbidity Measured With Coronary Computed Tomography Angiography.
CONCLUSIONS: An elevated CACS with the use of CCTA is an independent predictor of mid- to long-term cardiovascular mortality and morbidity in patients suspected of having CAD. PMID: 29984787 [PubMed - as supplied by publisher]
Source: Circulation Journal - July 6, 2018 Category: Cardiology Authors: Yamamoto H, Kitagawa T, Kunita E, Utsunomiya H, Senoo A, Nakamoto Y, Kihara Y Tags: Circ J Source Type: research

Sex-mediated response to landiolol, a ß1 selectif adrenergic blocker, in myocardial dysfunction during sepsis
ConclusionLandiolol improved the in vivo cardiac performance of septic male rats, in association with an improvement in diastolic function. However, in septic females, treatment with landiolol resulted in deleterious effects. Ongoing analysis of these signaling pathways will aid better understanding of sex differences occurring in sepsis.
Source: Archives of Cardiovascular Diseases Supplements - July 5, 2018 Category: Cardiology Source Type: research

Effects of blood pressure-lowering treatment on cardiovascular outcomes and mortality: 14 – effects of different classes of antihypertensive drugs in older and younger patients overview and meta-analysis
Conclusion: Most BP-lowering classes are equally effective in preventing risk of fatal and nonfatal cardiovascular events both in older and younger patients, whereas beta-blockers, though being equally effective as the other agents in patients younger than 65, loose some of their effectiveness at an older age.
Source: Journal of Hypertension - June 28, 2018 Category: Cardiology Tags: Meta-Analyses Source Type: research

Clinical characteristics and cardiovascular outcomes in patients with atrial fibrillation receiving rhythm-control therapy: the Fushimi AF Registry
AbstractManagement of atrial fibrillation (AF) with current rhythm-control therapy has an uncertain impact on outcomes. Among 3731 patients in the Fushimi AF Registry, a community-based prospective survey of AF patients in Fushimi-ku, Kyoto, we investigated the characteristics and outcomes in 478 patients receiving rhythm-control therapy (anti-arrhythmic drug and/or catheter ablation) alone, with 1279 patients receiving rate-control therapy (beta-blockers, calcium channel blockers, and digoxin) alone serving as a reference. The Rhythm-control group, 26% of which had prior catheter ablation, was younger (70.5  ± 10.8 v...
Source: Heart and Vessels - May 24, 2018 Category: Cardiology Source Type: research

Impact of Indoxyl Sulfate on Coronary Plaques in Patients on Hemodialysis.
This study aimed to interpret the association between serum IS levels and coronary plaque burden (CPB) or CAC.A total of 30 consecutive patients on hemodialysis, who underwent 320-row coronary multidetector computed tomography (MDCT) angiography for suspected coronary artery disease, were enrolled in this prospective study. Coronary artery percent atheroma volume (a CPB marker) and percent calcium volume (a CAC marker) assessed using MDCT were evaluated. Furthermore, various oxidative and inflammatory markers typified by serum IS levels at a dialysis-free day were measured. Using these data, we investigated correlation bet...
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Blood pressure-lowering drugs and secondary prevention of cardiovascular disease: systematic review and meta-analysis
Conclusions: Although only ACEIs have evidences showing its effect in reducing cardiovascular events and all secondary outcomes, head-to-head comparisons did not provide strong evidence in difference in the effects between these blood pressure-lowering drugs.
Source: Journal of Hypertension - May 1, 2018 Category: Cardiology Tags: Reviews Source Type: research

Outcomes with a latest generation self-expandable, intra-annular, re-sheathable transcatheter heart valve system: analysis of patients with impaired left ventricular function and determinants for pacemaker implantation
ConclusionsThe Portico valve demonstrates a satisfying safety outcome, especially for patients with impaired LV function. Results of the CE-mark trial were confirmed, except for higher PPM rates. PPM rates are in accordance with other reports on this TAVI platform.
Source: Clinical Research in Cardiology - April 28, 2018 Category: Cardiology Source Type: research

Ten-year association of coronary artery calcium with atherosclerotic cardiovascular disease (ASCVD) events: the multi-ethnic study of atherosclerosis (MESA)
ConclusionsCoronary artery calcium is associated strongly and in a graded fashion with 10-year risk of incident ASCVD as it is for CHD, independent of standard risk factors, and similarly by age, gender, and ethnicity. While 10-year event rates in those with CAC  = 0 were almost exclusively below 5%, those with CAC ≥ 100 were consistently above 7.5%, making these potentially valuable cutpoints for the consideration of preventive therapies. Coronary artery calcium strongly predicts risk with the same magnitude of effect in all races, age groups, an d both sexes, which makes it among the most useful markers for predicting ASCVD risk.
Source: European Heart Journal - April 23, 2018 Category: Cardiology Source Type: research