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Specialty: Cancer & Oncology
Condition: Depression

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Total 60 results found since Jan 2013.

Prevalence and Predictors of Current and Former Tobacco Use among Older Adults in Indonesia
Conclusions: A high rate of current tobacco use and low rate of former tobacco use was found, particularly among men. The identified risk factors may help to better target this vulnerable population with tobacco cessation programmes. PMID: 30803198 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - February 27, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Breast Cancer Screening Participation of Women with Chronic Diseases in Korea: Analysis of the 2012 Korean National Health and Nutrition Examination Survey
In conclusion, low participation rate in breast cancer screening in women with some chronic diseases was identified. The results from this study may provide an important contribution for helping to maintain and increase participation in cancer screening of patients with chronic diseases. PMID: 30678433 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - January 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

PCORI Board approves $85 million in new studies on opioids, cancer & other high-burden conditions
(Patient-Centered Outcomes Research Institute) The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved $85 million to fund 16 new studies comparing two or more approaches to improve care and outcomes for a range of conditions and problems that impose high burdens on patients, caregivers and the healthcare system, including unsafe opioid use, cancer, depression and stroke.
Source: EurekAlert! - Cancer - August 22, 2018 Category: Cancer & Oncology Source Type: news

Potassium 2-(1-hydroxypentyl)-benzoate improves depressive-like behaviors in rat model
In this study, we demonstrated that PHPB improved depressive-like behaviors induced by chronic unpredictable mild stress (CUMS) in rats. Male SD rats were subjected to the stress for five weeks. PHPB (30 and 100 mg/kg) or fluoxetine (FLX 10 mg/kg, as positive control) was administered orally from the third week in CUMS procedure. The behavioral tests were applied and then the biochemical studies were carried out. PHPB or FLX treatment rescued the behavioral deficiency in CUMS-exposed rats. Meanwhile, PHPB normalized the enhanced level of serum corticosterone, improved hippocampal and serum BDNF levels, as well as...
Source: Acta Pharmaceutica Sinica B - August 21, 2018 Category: Cancer & Oncology Source Type: research

Efficacy and tolerability of pharmacotherapy for post-stroke depression: a network meta-analysis.
Conclusions: Paroxetine is probably the best option to consider for patients with PSD. To get a quicker relief of depression, duloxetine might be useful for its rapid onset of antidepressant action. The tolerability was comparable among all the antidepressants. But more high-quality RCTs are needed. PMID: 29805769 [PubMed]
Source: Oncotarget - May 31, 2018 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

A risk prediction model for post-stroke depression in Chinese stroke survivors based on clinical and socio-psychological features.
CONCLUSION: This study provided an effective risk model for PSD and indicated that the socio-psychological factors were important risk factors of PSD. PMID: 28446713 [PubMed - as supplied by publisher]
Source: Oncotarget - April 29, 2017 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Towards a multi protein and mRNA expression of biological predictive and distinguish model for post stroke depression.
Authors: Yue Y, Jiang H, Liu R, Yin Y, Zhang Y, Liang J, Li S, Wang J, Lu J, Geng D, Wu A, Yuan Y Abstract Previous studies suggest that neurotrophic factors participate in the development of stroke and depression. So we investigated the utility of these biomarkers as predictive and distinguish model for post stroke depression (PSD). 159 individuals including PSD, stroke without depression (Non-PSD), major depressive disorder (MDD) and normal control groups were recruited and examined the protein and mRNA expression levels of vascular endothelial growth factor (VEGF), vascular endothelial growth factor receptors (V...
Source: Oncotarget - August 18, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Patient Engagement in Randomized Controlled Clinical Trials with Tai Chi Intervention.
CONCLUSION: Considering that the purpose of Tai Chi practice is to integrate and balance all aspects of a patient's life, we hope to use Tai Chi intervention as an example to illustrate patient engagement process. However, we found that patient engagement, as a concept, was not well defined. It covers a wide range of related terms, such as patient involvement, participation, shared decision-making, patient activation, adherence, compliance, and self-management. Novel research design may explore ways to measure patient engagement in such complex interventions to help identify its specific role on health. PMID: 27527892...
Source: Reviews on Recent Clinical Trials - August 14, 2016 Category: Cancer & Oncology Authors: Jiang D, Kong W, Jiang JJ Tags: Rev Recent Clin Trials Source Type: research

Up-regulation of serotonin receptor 2B mRNA and protein in the peri-infarcted area of aged rats and stroke patients.
Authors: Buga AM, Ciobanu O, Bădescu GM, Bogdan C, Weston R, Slevin M, DiNapoli M, Popa-Wagner A Abstract Despite the fact that a high proportion of elderly stroke patients develop mood disorders, the mechanisms underlying late-onset neuropsychiatric and neurocognitive symptoms have so far received little attention in the field of neurobiology. In rodents, aged animals display depressive symptoms following stroke, whereas young animals recover fairly well. This finding has prompted us to investigate the expression of serotonin receptors 2A and 2B, which are directly linked to depression, in the brains of aged and ...
Source: Oncotarget - March 27, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Cancer is associated with intraoperative and postprocedural complications and disorders
Conclusion The present study indicates that cancer increases the risk of IPCs and may reduce the clinical benefits of surgery.
Source: Journal of Cancer Research and Clinical Oncology - December 9, 2015 Category: Cancer & Oncology Source Type: research

Patient preference and decision-making for initiating metastatic colorectal cancer medical treatment.
CONCLUSIONS: Variations in patients' willingness to tolerate different treatment-related adverse events underscore the need for improved communications between physicians and patients about the risks and benefits of their medical treatment, which helps make a more personalized decision for metastatic CRC treatment. PMID: 26577827 [PubMed - as supplied by publisher]
Source: Clinical Colorectal Cancer - November 18, 2015 Category: Cancer & Oncology Authors: Fu AZ, Graves KD, Jensen RE, Marshall JL, Formoso M, Potosky AL Tags: J Cancer Res Clin Oncol Source Type: research

Patient preference and decision-making for initiating metastatic colorectal cancer medical treatment
Conclusions Variations in patients’ willingness to tolerate different treatment-related adverse events underscore the need for improved communications between physicians and patients about the risks and benefits of their medical treatment, which helps make a more personalized decision for metastatic CRC treatment.
Source: Journal of Cancer Research and Clinical Oncology - November 18, 2015 Category: Cancer & Oncology Source Type: research

An occupational therapy intervention for residents with stroke related disabilities in UK care homes (OTCH): cluster randomised controlled trial.
CONCLUSIONS: This large phase III study provided no evidence of benefit for the provision of a routine occupational therapy service, including staff training, for care home residents living with stroke related disabilities. The established three month individualised course of occupational therapy targeting stroke related disabilities did not have an impact on measures of functional activity, mobility, mood, or health related quality of life, at all observational time points. Providing and targeting ameliorative care in this clinically complex population requires alternative strategies.Trial registration Current Controlled ...
Source: Cancer Control - February 8, 2015 Category: Cancer & Oncology Authors: Sackley CM, Walker MF, Burton CR, Watkins CL, Mant J, Roalfe AK, Wheatley K, Sheehan B, Sharp L, Stant KE, Fletcher-Smith J, Steel K, Wilde K, Irvine L, Peryer G, OTCH trial investigators Tags: BMJ Source Type: research

UEA research shows group walking cuts risk of life-threatening conditions
(University of East Anglia) Risk of stroke, coronary heart disease, depression and other life-threatening conditions can be reduced through regular outdoor walking in groups, according to research from the University of East Anglia. Findings published today in the British Journal of Sports Medicine reveal that people who regularly walk in groups have lower blood pressure, resting heart rate and total cholesterol.
Source: EurekAlert! - Cancer - January 19, 2015 Category: Cancer & Oncology Source Type: news

Bm-19 * symptomatic and economic burden of brain metastases in patients with alk+ nsclc
CONCLUSIONS: BM presents a substantial symptomatic and economic burden in patients with ALK+ NSCLC. Given the large percentage of ALK+ NSCLC patients who will eventually develop BM, this highlights an important unmet need.
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Macalalad, A., Sasane, M., Zhang, J., Culver, K., Dea, K., Nitulescu, R., Wu, E., Guerin, A. Tags: BRAIN METASTASES (CLINICAL AND/OR LABORATORY RESEARCH) Source Type: research