Filtered By:
Specialty: Internal Medicine
Condition: Coronary Heart Disease

This page shows you your search results in order of date. This is page number 9.

Order by Relevance | Date

Total 149 results found since Jan 2013.

Physical activity reduces cardiovascular disease risk in older adults
Commentary on: Soares-Miranda L, Siscovick DS, Psaty BM, et al.. Physical activity and risk of coronary heart disease and stroke in older adults: the cardiovascular health study. Circulation 2016;133:147–55 . Context Currently, at least 150 min per week of moderate-to-vigorous physical activity is recommended for adults of all ages to beneficially influence individual and population health and cardiovascular mortality.1 Adhering to current physical activity guidelines has been shown to be associated with a 20% lower mortality risk compared to physically inactive persons.2 A physically active lifestyle is linked ...
Source: Evidence-Based Medicine - September 22, 2016 Category: Internal Medicine Authors: Endes, S. Tags: Epidemiologic studies, Drugs: cardiovascular system, Stroke, Ischaemic heart disease, Sports and exercise medicine Aetiology/Harm Source Type: research

Potential health hazards of eating red meat
Abstract Red meat (beef, veal, pork, lamb and mutton) consumption contributes several important nutrients to the diet, for example essential amino acids, vitamins (including B12) and minerals (including iron and zinc). Processed red meat (ham, sausages, bacon, frankfurters, salami, etc.) undergoes treatment (curing, smoking, salting or the use of chemical preservatives and additives) to improve its shelf life and/or taste. During recent decades, consumption of red meat has been increasing globally, especially in developing countries. At the same time, there has been growing evidence that high consumption of red meat, espec...
Source: Journal of Internal Medicine - August 31, 2016 Category: Internal Medicine Authors: A. Wolk Tags: Review Source Type: research

Glycaemic control and cardiovascular disease: is there a light at the end of the tunnel?
AbstractPatients with type 2 diabetes mellitus (T2DM) have been shown by numerous studies to have a substantially increased risk of cardiovascular disease (CVD), including coronary artery disease, ischemic stroke and heart failure, even after adjusting for other known risk factors.1,2 First reported in the Framingham studies and followed by additional data including a meta-analysis of 102 prospective studies, diabetes confers about a two-fold excess risk for coronary heart disease and ischemic stroke in both men and women, and about a 2-fold and 5-fold excess risk of heart failure in diabetic men and women.1 –3 However, ...
Source: QJM - August 13, 2016 Category: Internal Medicine Source Type: research

Proprotein convertase subtilisin kexin 9 (PCSK9) inhibitors to treat hypercholesterolemia: Effect on stroke risk.
CONCLUSION: Although a benefit towards reduction of cardiovascular events in the overall has been documented, longer exposure is warranted to be able to evaluate the effect on stroke risk. PMID: 27363304 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - June 27, 2016 Category: Internal Medicine Authors: Milionis H, Barkas F, Ntaios G, Papavasileiou V, Vemmos K, Michel P, Elisaf M Tags: Eur J Intern Med Source Type: research

Daytime sleepiness is associated with hyperhomocysteinemia in rural area of China: A cross-sectional study.
CONCLUSIONS: Daytime sleepiness, but not sleep duration abnormity, snoring, apnea and sleep disruption was an independent risk factor for Hhcy. PMID: 27321249 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - June 15, 2016 Category: Internal Medicine Authors: Zhang N, Chen S, Chen Y, Guo X, Sun G, Qian H, Sun Y Tags: Eur J Intern Med Source Type: research

Hypertension, the Swedish Patient Register, and Selection Bias
In Reply We recently reported that high body mass index (BMI) and low aerobic fitness in a large cohort of 18-year-old Swedish men were associated with increased risk of hypertension in adulthood. Hypertension was ascertained using all inpatient diagnoses nationwide throughout the study period (1969-2012) and outpatient diagnoses from all specialty clinics between 2001 and 2012. We indicated that hypertension was therefore underreported because we lacked outpatient data before 2001 or from primary care clinics. Dr Brunström raises the question of whether our findings may be attributable to the known associations between h...
Source: JAMA Internal Medicine - June 1, 2016 Category: Internal Medicine Source Type: research

The Pooled Cohort Equations for Predicting Risk of Myocardial Infarction and Stroke: Validated in Representative Natural History Populations
The American College of Cardiology (ACC)/American Heart Association (AHA) Pooled Cohort equations (PCEs) were introduced in late 2013 and published in mid-2014.1 Unlike the Framingham score used to determine coronary heart disease (CHD) risk in the National Cholesterol Education Program Adult Treatment Panel III guidelines,2 the new PCEs focused on estimating risk of CHD and stroke and additionally provided specific risk assessment for African American individuals. Because stroke may occur before CHD, particularly in women and African Americans, the PCEs were seen as a major advance in disease prognostication.
Source: Mayo Clinic Proceedings - May 10, 2016 Category: Internal Medicine Authors: Neil J. Stone, Donald M. Lloyd-Jones Tags: Editorial Source Type: research

The Kinetics of Circulating Monocyte Subsets and Monocyte-Platelet Aggregates in the Acute Phase of ST-Elevation Myocardial Infarction: Associations with 2-Year Cardiovascular Events
In conclusion, our data show the expansion of the CD14++CD16+ monocyte subset during acute phase of STEMI has predictive values for 2-year adverse cardiovascular outcomes in patients treated with primary PCI. Future studies will be warranted to elucidate whether CD14++CD16+ monocytes may become a target cell population for new therapeutic strategies after STEMI.
Source: Medicine - May 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Comparative Effectiveness of Blood Pressure-lowering Drugs in Patients who have Already Suffered From Stroke: Traditional and Bayesian Network Meta-analysis of Randomized Trials
Abstract: Hypertension is the most important risk factor for stroke and stroke recurrence. However, the preferred blood pressure (BP)-lowering drug class for patients who have suffered from a stroke has yet to be determined. To investigate the relative effects of BP-lowering therapies [angiotensin-converting enzyme inhibitor (ACEI), angiotensin receptor blockers (ARB), β blockers, calcium channel blockers (CCBs), diuretics, and combinations of these drugs] in patients with a prior stroke history, we performed a systematic review and meta-analysis using both traditional frequentist and Bayesian random-effects models and m...
Source: Medicine - April 1, 2016 Category: Internal Medicine Tags: Research Article: Systematic Reviewand Meta-Analysis Source Type: research

Effect of prestroke antiplatelets use on first‐ever ischaemic stroke severity and early outcome
ConclusionsOur findings provide further evidence supporting modest benefit of AP therapy on the course and outcome of first‐ever ischaemic stroke. Further large studies are needed to confirm this effect.
Source: International Journal of Clinical Practice - March 31, 2016 Category: Internal Medicine Authors: J. P. Bembenek, M. Niewada, M. Karlinski, A. Czlonkowska Tags: Original Paper Source Type: research

Significant interactions between traditional risk factors affect cardiovascular risk prediction in healthy general population.
CONCLUSIONS: There are significant effect modifications between major risk factors, and accounting for them leads to significantly more accurate estimation of cardiovascular risk. PMID: 25405541 [PubMed - indexed for MEDLINE]
Source: Annals of Medicine - February 18, 2016 Category: Internal Medicine Tags: Ann Med Source Type: research

Increased Risk of Stroke in Patients With Fibromyalgia: A Population-BASED Cohort Study
Abstract: Neuropsychiatric diseases might enhance stroke development, possibly through inflammation and atherosclerosis. Approximately 25% to 40% of patients with stroke, largely younger patients, are not associated with any conventional stroke risk factors. In this research, we explored whether fibromyalgia (FM), a neuropsychosomatic disorder, increases stroke risk. From a claims dataset with one million enrollees sourced of the Taiwan National Health Insurance database, we selected 47,279 patients with FM and randomly selected 189,112 age- and sex-matched controls within a 3-year period from January 1, 2000 to December ...
Source: Medicine - February 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Level of circulating endothelial cells and expression of nuclear factor kappa beta of human's peripheral blood mononuclear cells in subjects with certain conditions.
CONCLUSION: increase of level CEC and NFκB expression has a strong relationship with vascular disease and its risk factors. PMID: 24760806 [PubMed - indexed for MEDLINE]
Source: Acta medica Indonesiana - December 11, 2015 Category: Internal Medicine Tags: Acta Med Indones Source Type: research

Association of Gallbladder Polyp and Stroke: A Nationwide, Population-Based Study
Abstract: Gallbladder polyp (GP) and stroke share several metabolic disorders as risk factors. We assessed the association between GP and subsequent stroke risk. From 2000 to 2011, patients with GP aged>20 years were identified from the Longitudinal Health Insurance Database 2000. Of the 15,975 examined patients, 12,780 and 3195 were categorized into the non-GP and GP cohorts, respectively. The relative risks of stroke were estimated using the Cox proportional hazard model after adjusting for age, sex, and comorbidities. The overall incidence of stroke was higher in the GP cohort than in the non-GP cohort (6.66 vs 5.20/100...
Source: Medicine - December 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Blood pressure lowering in patients with type 2 diabetes improves cardiovascular events including mortality, but more intensive lowering to systolic blood pressure less than 130 mm Hg is associated with further reduction in stroke and albuminuria without further reduction in cardiac events
Commentary on: Emdin CA, Rahimi K, Neal B, et al. Blood pressure lowering in type 2 diabetes: a systematic review and meta-analysis. JAMA 2015;313:603–15. Context Hypertension and diabetes are independent risk factors for cardiovascular disease.1 Although lowering blood pressure (BP) reduces cardiovascular events,1 thresholds to initiate antihypertensive therapy and BP targets have been areas of controversy. Until recently, guideline recommendations for BP targets have been more stringent in patients with diabetes. Methods Emdin and colleagues report information from a systematic review of 45 randomised trials. The t...
Source: Evidence-Based Medicine - September 24, 2015 Category: Internal Medicine Authors: Toklu, B., Bangalore, S. Tags: Epidemiologic studies, Drugs: cardiovascular system, Stroke, Hypertension, Ischaemic heart disease, Renal medicine, Diabetes Therapeutics/Prevention Source Type: research