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French National Diagnostic and Care Protocol for antiphospholipid syndrome in adults and children
Rev Med Interne. 2023 Sep 19:S0248-8663(23)00711-7. doi: 10.1016/j.revmed.2023.08.004. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is a chronic autoimmune disease involving vascular thrombosis and/or obstetric morbidity and persistent antibodies to phospholipids or certain phospholipid-associated proteins. It is a rare condition in adults and even rarer in children. The diagnosis of APS can be facilitated by the use of classification criteria based on a combination of clinical and biological features. APS may be rapidly progressive with multiple, often synchronous thromboses, resulting in life-threatening...
Source: Revue de Medecine Interne - September 21, 2023 Category: Internal Medicine Authors: Z Amoura B Bader-Meunier C Bal Dit Sollier A Belot Y Benhamou H Bezanahary F Cohen N Costedoat-Chalumeau L Darnige L Drouet E Elefant A Harroche M Lambert T Martin I Martin-Toutain A Mathian A Mekinian M Pineton De Chambrun L de Pontual D Wahl C Yelnik S Source Type: research
Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses
Despite epidemiological evidence associating gallstone disease (GSD) with cardiovascular disease (CVD), a dilemma remains on the role of cholecystectomy in modifying the risk of CVD. We aimed to characterize t...
Source: BMC Medicine - September 13, 2023 Category: Internal Medicine Authors: Li Zhang, Wenqiang Zhang, Lin He, Huijie Cui, Yutong Wang, Xueyao Wu, Xunying Zhao, Peijing Yan, Chao Yang, Changfeng Xiao, Mingshuang Tang, Lin Chen, Chenghan Xiao, Yanqiu Zou, Yunjie Liu, Yanfang Yang & hellip; Tags: Research article Source Type: research
Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery : A Nationwide Cohort Study
CONCLUSION: These results suggest that atypical antipsychotics and haloperidol have similar rates of in-hospital adverse clinical events in older patients with postoperative delirium who receive an oral low-to-moderate dose antipsychotic drug.PRIMARY FUNDING SOURCE: National Institute on Aging.PMID:37665998 | DOI:10.7326/M22-3021
Source: Annals of Internal Medicine - September 4, 2023 Category: Internal Medicine Authors: Dae Hyun Kim Su Been Lee Chan Mi Park Raisa Levin Eran Metzger Brian T Bateman E Wesley Ely Pratik P Pandharipande Margaret A Pisani Richard N Jones Edward R Marcantonio Sharon K Inouye Source Type: research
Efficacy of ablation therapy on clinical outcomes in patients with atrial fibrillation: a systematic review and meta-analysis
CONCLUSION: Ablation significantly reduces the risk of stroke, cardiovascular mortality, all-cause mortality, and HF in AF patients, compared with medical therapy alone, supporting its use in clinical practice.PMID:37663739 | PMC:PMC10473299 | DOI:10.1097/MS9.0000000000000985
Source: Annals of Medicine - September 4, 2023 Category: Internal Medicine Authors: Mohammad Munim Zahoor Saad Ehsan Ullah Harriet Mmaitsi Kidiavai Shahda A H Eltieb Anjuli Devi Muhammad Anis Asif Akshay Vaswani Ammar Hyder Muhammad Roshan Hoti Sayed Jawad Sana Arshid Abhirami Shankar Muhammad Salman Source Type: research
Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery : A Nationwide Cohort Study
CONCLUSION: These results suggest that atypical antipsychotics and haloperidol have similar rates of in-hospital adverse clinical events in older patients with postoperative delirium who receive an oral low-to-moderate dose antipsychotic drug.PRIMARY FUNDING SOURCE: National Institute on Aging.PMID:37665998 | DOI:10.7326/M22-3021
Source: Annals of Internal Medicine - September 4, 2023 Category: Internal Medicine Authors: Dae Hyun Kim Su Been Lee Chan Mi Park Raisa Levin Eran Metzger Brian T Bateman E Wesley Ely Pratik P Pandharipande Margaret A Pisani Richard N Jones Edward R Marcantonio Sharon K Inouye Source Type: research
Exploring the transformative influence of neuroplasticity on stroke rehabilitation: a narrative review of current evidence
Ann Med Surg (Lond). 2023 Aug 7;85(9):4425-4432. doi: 10.1097/MS9.0000000000001137. eCollection 2023 Sep.ABSTRACTThis review aims to assess the role of neuroplasticity in facilitating stroke recovery and identify the challenges and limitations associated with its implementation. A comprehensive literature search was conducted to identify relevant studies, which were meticulously evaluated to determine the potential solutions for effectively harnessing neuroplasticity. The results indicate that neuroplasticity holds significant promise in stroke rehabilitation; however, individual variability in response to interventions, t...
Source: Annals of Medicine - September 4, 2023 Category: Internal Medicine Authors: Nicholas Aderinto Muili O AbdulBasit Gbolahan Olatunji Temilade Adejumo Source Type: research
Efficacy of ablation therapy on clinical outcomes in patients with atrial fibrillation: a systematic review and meta-analysis
CONCLUSION: Ablation significantly reduces the risk of stroke, cardiovascular mortality, all-cause mortality, and HF in AF patients, compared with medical therapy alone, supporting its use in clinical practice.PMID:37663739 | PMC:PMC10473299 | DOI:10.1097/MS9.0000000000000985
Source: Annals of Medicine - September 4, 2023 Category: Internal Medicine Authors: Mohammad Munim Zahoor Saad Ehsan Ullah Harriet Mmaitsi Kidiavai Shahda A H Eltieb Anjuli Devi Muhammad Anis Asif Akshay Vaswani Ammar Hyder Muhammad Roshan Hoti Sayed Jawad Sana Arshid Abhirami Shankar Muhammad Salman Source Type: research
Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery : A Nationwide Cohort Study
CONCLUSION: These results suggest that atypical antipsychotics and haloperidol have similar rates of in-hospital adverse clinical events in older patients with postoperative delirium who receive an oral low-to-moderate dose antipsychotic drug.PRIMARY FUNDING SOURCE: National Institute on Aging.PMID:37665998 | DOI:10.7326/M22-3021
Source: Annals of Internal Medicine - September 4, 2023 Category: Internal Medicine Authors: Dae Hyun Kim Su Been Lee Chan Mi Park Raisa Levin Eran Metzger Brian T Bateman E Wesley Ely Pratik P Pandharipande Margaret A Pisani Richard N Jones Edward R Marcantonio Sharon K Inouye Source Type: research
Exploring the transformative influence of neuroplasticity on stroke rehabilitation: a narrative review of current evidence
Ann Med Surg (Lond). 2023 Aug 7;85(9):4425-4432. doi: 10.1097/MS9.0000000000001137. eCollection 2023 Sep.ABSTRACTThis review aims to assess the role of neuroplasticity in facilitating stroke recovery and identify the challenges and limitations associated with its implementation. A comprehensive literature search was conducted to identify relevant studies, which were meticulously evaluated to determine the potential solutions for effectively harnessing neuroplasticity. The results indicate that neuroplasticity holds significant promise in stroke rehabilitation; however, individual variability in response to interventions, t...
Source: Annals of Medicine - September 4, 2023 Category: Internal Medicine Authors: Nicholas Aderinto Muili O AbdulBasit Gbolahan Olatunji Temilade Adejumo Source Type: research
Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery : A Nationwide Cohort Study
CONCLUSION: These results suggest that atypical antipsychotics and haloperidol have similar rates of in-hospital adverse clinical events in older patients with postoperative delirium who receive an oral low-to-moderate dose antipsychotic drug.PRIMARY FUNDING SOURCE: National Institute on Aging.PMID:37665998 | DOI:10.7326/M22-3021
Source: Annals of Internal Medicine - September 4, 2023 Category: Internal Medicine Authors: Dae Hyun Kim Su Been Lee Chan Mi Park Raisa Levin Eran Metzger Brian T Bateman E Wesley Ely Pratik P Pandharipande Margaret A Pisani Richard N Jones Edward R Marcantonio Sharon K Inouye Source Type: research
Hypertriglyceridemia-Induced Pseudo –High Anion Gap Metabolic Acidosis Manifesting as Ischemic Stroke
Hypertriglyceridemia is a metabolic disorder characterized by elevated levels of triglycerides in the bloodstream.1 The underlying causes are multifactorial and range from metabolic syndrome and genetic predisposition to lifestyle choices.1 The management of hypertriglyceridemia usually involves a combination of lifestyle modifications, control of low-density lipoprotein and high-density lipoprotein levels, and pharmacotherapy when necessary.1 The clinical presentation is predominantly asymptomatic; however, some patients present with abdominal pain, nausea, vomiting, and pancreatitis.
Source: Mayo Clinic Proceedings - September 1, 2023 Category: Internal Medicine Authors: Abdul R. Akkawi, Mason Fawcett, Abhiram Challa, Timothy Nguyen, Jennifer Jackson, Richard Muraga Tags: Letter to the editor Source Type: research
Natural History and Sequelae of Penetrating Aortic Ulcer
A man in his 70s with history of tobacco use and hypertension presented for transesophageal echocardiography after a recent diagnosis of ischemic stroke. This demonstrated a moderate right-to-left shunt on Valsalva release and no left atrial appendage thrombus. Assessment of the thoracic aorta revealed a complex penetrating aortic ulcer and saccular aneurysm with thrombus in the distal arch and proximal descending thoracic aorta (Figure). Computed tomography angiography confirmed the presence of multiple penetrating ulcerations with large saccular aneurysms.
Source: Mayo Clinic Proceedings - September 1, 2023 Category: Internal Medicine Authors: Raghav R. Julakanti, Prabhakar Shantha Rajiah, Krishnaswamy Chandrasekaran Tags: Medical image Source Type: research
Safeguarding Against Stroke Risk by Statins
Whereas mighty prospective randomized trials —and meta-analyses of these—rightly command the data used to drive guidelines and daily clinical practice, careful long-term follow-up of closely monitored cohorts can generate crucial discoveries not anticipated in a 5-year study. As just one example, findings from lifelong follow-up in the Ame rican Framingham studies and the Whitehall cohorts in the United Kingdom show a strong association between blood pressure in middle years and dementia in later life.
Source: Mayo Clinic Proceedings - September 1, 2023 Category: Internal Medicine Authors: Adrian J.B. Brady Tags: Editorial Source Type: research
