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Total 345 results found since Jan 2013.

Extending the window for thrombolysis for treatment of acute ischemic stroke during pregnancy: a review.
Abstract Historically, safety of intravenous recombinant tissue plasminogen activator (IV rt-PA) for the treatment of acute ischemic stroke (AIS) is limited to use within 4.5 hours from symptom onset. Recent studies suggest the treatment window may be extended when patients have salvageable brain tissue on advanced neuroimaging. This paper describes a novel use of IV rt-PA for treatment of AIS in a pregnant patient within an extended-time window (>4.5 hours, and <9hrs) based on advanced neuroimaging with a favorable outcome. PMID: 32920999 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 11, 2020 Category: OBGYN Authors: Dinehart E, Leon Guerrero CR, Pham A, Chandra S, Petersen SM, Bathgate S, Ahmadzia HK Tags: BJOG Source Type: research

Fetal cardiovascular hemodynamics in type 1 diabetic pregnancies at near term gestation
ConclusionsIn maternal type 1 diabetes pregnancies, fetal cardiovascular hemodynamics is impaired. Maternal type 1 diabetes does not seem to alter placental vascular impedance or induce placental inflammation.
Source: Acta Obstetricia et Gynecologica Scandinavica - September 1, 2020 Category: OBGYN Authors: Lara Lehtoranta, Mervi Haapsamo, Olli Vuolteenaho, Pertti Palo, Eeva Ekholm, Juha R äsänen Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Finding the everyday miracles in life
Last week I was writing about what it takes for a miracle to happen and one of my commentators, the lovely Patsy Collins who joined me on the podcast not that long ago, pointed out that there are all sorts of miracles that happen, including some everyday miracles we never know about, because they happen behind the scenes. And it got me thinking about the all the little miracles that have happened in my life over the years. And, once I got thinking, I got into musing about what life would be like if they hadn’t happened. And, as it’s been a week of ups and downs on the exam front I thought I might as well start ...
Source: The Hysterectomy Association - August 22, 2020 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Happiness miracle Source Type: news

Multi-compartment MRI as a promising tool for measurement of placental perfusion and oxygenation in early onset Fetal Growth Restriction.
Abstract Placental insufficiency, the main cause of Fetal Growth Restriction (FGR), is associated with adverse outcomes for both the mother and infant in the short term, but also with negative longer-term effects (such as heart disease, diabetes and stroke). Doppler Ultrasound is the main means of assessing placental function in clinical practice, but does not necessarily allow a precise distinction between placental insufficiency with secondary FGR, and normal placental function with a constitutionally small fetus. PMID: 32772422 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - August 7, 2020 Category: OBGYN Authors: Jacquier M, Salomon LJ Tags: BJOG Source Type: research

The Real Maternal Risks in a Pregnancy: A Structured Review to Enhance Maternal Understanding and Education.
Authors: Wilson RD Abstract This review sought to use high-level published data sources for system knowledge translation, collaborative enhanced maternal education and understanding, and prospective maternal quality and safety care planning. The goal was to answer the following question: What are the short- and long-term maternal risks ("near misses," adverse events, severe morbidity and mortality) associated with pregnancy and childbirth? A structured analysis of the literature (systematic review, meta-analysis, observational case-control cohort), focusing on publications between 2016 and April 2019, was undertake...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - July 28, 2020 Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research

Things I know to be true 1 – We are all walking miracles
Back when I was child I genuinely believed that when my mother kissed my knee to make it better, she did actually do that. And as I grew older although that belief faded away in the light of the obvious ‘fact’ of the medical model, it never truly disappeared. Time and again I would reflect on what it meant to be healthy and when my own health challenges began in my mid-teens, some part of me always knew that my mother’s kiss held meaning. I remember being 16 years old and just about to sit ‘O’ levels, as they were then. I had been having a period for what must have been weeks and I was tired a...
Source: The Hysterectomy Association - June 25, 2020 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health life miracle Source Type: news

Things I know to be true – We are all walking miracles
Back when I was child I genuinely believed that when my mother kissed my knee to make it better, she did actually do that. And as I grew older although that belief faded away in the light of the obvious ‘fact’ of the medical model, it never truly disappeared. Time and again I would reflect on what it meant to be healthy and when my own health challenges began in my mid-teens, some part of me always knew that my mother’s kiss held meaning. I remember being 16 years old and just about to sit ‘O’ levels, as they were then. I had been having a period for what must have been weeks and I was tired a...
Source: The Hysterectomy Association - June 25, 2020 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health 3 principles life miracle Source Type: news

The Women's Health Initiative Estrogen-alone Trial had differential disease and medical expenditure consequences across age groups
Conclusion: The decline in ET utilization had differential disease and expenditure consequences by age groups in the United States. These results are limited by the lack of inclusion of vasomotor symptom benefit and costs of alternative medications for these symptoms in the analysis.
Source: Menopause - May 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Coronavirus disease 2019 in pregnancy: consider thromboembolic disorders and thromboprophylaxis
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory distress syndrome coronavirus 2. This syndrome generally begins with respiratory symptoms that may progress to single-organ dysfunction (ie, respiratory failure) and then to multiorgan failure and death. In nonpregnant patients admitted to the intensive care unit with COVID-19 pneumonia, the frequency of venous thromboembolic disorders is 25% (20 of 81) detected by ultrasound examination of the lower extremities.1 In another series of 184 patients with confirmed COVID-19 pneumonia, 31% of patients had venous or arterial thromboembolism (defined as ac...
Source: American Journal of Obstetrics and Gynecology - April 21, 2020 Category: OBGYN Authors: Gian Carlo Di Renzo, Irene Giardina Tags: Letter to the Editors Source Type: research

Aspirin and pre-eclampsia: the heart of the matter?
Abstract Ling and colleagues (BJOG 2020 xxxx) have contributed important information on cardiovascular (CV) assessment over the course of pregnancy, with and without aspirin treatment, associated with risk of pre-term pre-eclampsia, as assessed by the multivariable competing risks model at 11-13 weeks. There are a number of important messages in these data. First, women at low- (vs. high-) risk of preterm pre-eclampsia appear to have lower cardiac output (CO), stroke volume (SV), and blood pressure (BP) in early pregnancy, consistent with the hypothesis that maternal CV predisposition plays a major role in pre-ecl...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - March 29, 2020 Category: OBGYN Authors: Hofmeyr GJ, Magee LA Tags: BJOG Source Type: research