Extending the window for thrombolysis for treatment of acute ischemic stroke during pregnancy: a review.

Extending the window for thrombolysis for treatment of acute ischemic stroke during pregnancy: a review.
BJOG. 2020 Sep 12;:
Authors: Dinehart E, Leon Guerrero CR, Pham A, Chandra S, Petersen SM, Bathgate S, Ahmadzia HK
Abstract
Historically, safety of intravenous recombinant tissue plasminogen activator (IV rt-PA) for the treatment of acute ischemic stroke (AIS) is limited to use within 4.5 hours from symptom onset. Recent studies suggest the treatment window may be extended when patients have salvageable brain tissue on advanced neuroimaging. This paper describes a novel use of IV rt-PA for treatment of AIS in a pregnant patient within an extended-time window (>4.5 hours, and <9hrs) based on advanced neuroimaging with a favorable outcome.
PMID: 32920999 [PubMed - as supplied by publisher]

Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 11, 2020 Category: OBGYN Authors: Dinehart E, Leon Guerrero CR, Pham A, Chandra S, Petersen SM, Bathgate S, Ahmadzia HK Tags: BJOG Source Type: research