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Total 2594 results found since Jan 2013.

Abnormal resting-state function within language network and its improvement among post-stroke aphasia
Behav Brain Res. 2023 Feb 11:114344. doi: 10.1016/j.bbr.2023.114344. Online ahead of print.ABSTRACTSeveral studies with resting-state magnetic resonance imaging (rs-fMRI) have examined functional impairments and plasticity within language network in patients with post-stroke aphasia (PSA). However, there is still ubiquitous inconsistency across these studies, partly due to restricted to very small sample size and the absence of validation with follow-up data. In the current study, we aimed at providing relatively strong evidence to support functional impairments and its reorganization in PSA. Here, the amplitude of low fre...
Source: Brain Research - February 13, 2023 Category: Neurology Authors: Xiaohui Xie Panpan Hu Yanghua Tian Bensheng Qiu Kai Wang Tongjian Bai Source Type: research

Sex differences and risk factors in recurrent ischemic stroke
ConclusionHypertension and dyslipidemia were significant risk factors of recurrent ischemic stroke in both genders. Smoking and alcohol drinking were significant risk factors associated with ischemic stroke recurrence in males. Therefore, smoking cessation and alcohol abstinence are recommended after the first stroke to prevent recurrent ischemic stroke especially for males. Diabetes was a significant risk factor of ischemic stroke recurrence in females. More extensive studies are needed to understand the causal relationship of each factors with ischemic stroke recurrence according to sex differences and specification of p...
Source: Frontiers in Neurology - January 26, 2023 Category: Neurology Source Type: research

Identifying vulnerable plaques: A 3D carotid plaque radiomics model based on HRMRI
ConclusionsHRMRI-based 3D carotid radiomics models can improve the precision of detecting vulnerable carotid plaques, consequently improving risk classification and clinical decision-making in patients with carotid stenosis.
Source: Frontiers in Neurology - January 26, 2023 Category: Neurology Source Type: research

Pre- and in-hospital delays in the use of thrombolytic therapy for patients with acute ischemic stroke in rural and urban Egypt
ConclusionThe limited availability of stroke-ready hospitals in rural Egypt leads to delays in stroke management, with subsequent treatment inequality of rural patients with acute stroke.
Source: Frontiers in Neurology - January 20, 2023 Category: Neurology Source Type: research

Associations of carotid artery flow parameters with MRI markers of cerebral small vessel disease and patterns of brain atrophy
Cerebral small vessel disease (CSVD) affects small arteries, arterioles, veins and capillaries of the brain. Although a common and often silent condition occurring among healthy elderly people, it is associated with stroke, dementia, gait disturbances, cognitive decline and depression.1 –4 Magnetic resonance imaging (MRI) markers of CSVD include: white matter changes (WMC), microbleeds (MB) and lacunar infarctions (LAC).5 They can be investigated either individually or be viewed as a dynamic whole-brain disease.
Source: Journal of Stroke and Cerebrovascular Diseases - January 18, 2023 Category: Neurology Authors: Katarina Ellstr öm, Kasim Abul-Kasim, Arkadiusz Siennicki-Lantz, Sölve Elmståhl Source Type: research

Association between Serum Amyloid A Level and White Matter Hyperintensity Burden: a Cross-Sectional Analysis in Patients with Acute Ischemic Stroke
ConclusionSAA level ranging from 2.12 to 19.89  mg/L is dose-dependently associated with periventricular WMH development. These findings point the way forward for future research into the pathophysiology of WMH.
Source: Neurology and Therapy - January 12, 2023 Category: Neurology Source Type: research

Image-to-image generative adversarial networks for synthesizing perfusion parameter maps from DSC-MR images in cerebrovascular disease
Stroke is a major cause of death or disability. As imaging-based patient stratification improves acute stroke therapy, dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is of major interest in image brain perfusion. However, expert-level perfusion maps require a manual or semi-manual post-processing by a medical expert making the procedure time-consuming and less-standardized. Modern machine learning methods such as generative adversarial networks (GANs) have the potential to automate the perfusion map generation on an expert level without manual validation. We propose a modified pix2pix GAN with a tempo...
Source: Frontiers in Neurology - January 10, 2023 Category: Neurology Source Type: research

Investigation of inpatient convalescent rehabilitation outcomes in branch atheromatous disease
Branch atheromatous disease (BAD) is a form of ischemic stroke characterized by unique findings in penetrating artery infarcts on magnetic resonance imaging (MRI) and progressive motor deficits in the acute phase.1-5 In daily practice, the most prominent clinical issue in patients with BAD is neurological deterioration and the consequent development of severe neurological sequelae requiring rehabilitation.
Source: Journal of Stroke and Cerebrovascular Diseases - January 6, 2023 Category: Neurology Authors: Joe Senda, Keiichi Ito, Tomomitsu Kotake, Masanori Mizuno, Hideo Kishimoto, Keizo Yasui, Masahisa Katsuno, Yoshihiro Nishida, Gen Sobue Source Type: research

Epileptic nystagmus in MELAS and non-mitochondrial disorders
We eagerly read the article by Aykac et  al. about 20 patients with horizontal epileptic nystagmus [1]. One of these patients was reported as having mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome [1]. It was found that the ictal discharge pattern was rhythmic fast activity with a mean frequency o f 15 Hz, that ictal discharges originated from the parieto-occipital, temporo-occipital, parieto-occipito-temporal, temporal, occipital, or centro-parietal areas, that the fast phase of the nystagmus was beating away from the side of ictal discharges, and that the origin of the ictal disc...
Source: Seizure: European Journal of Epilepsy - January 1, 2023 Category: Neurology Authors: Josef Finsterer Tags: Letter to the editor Source Type: research

Dizziness in a tertiary neurological department: A cross ‐sectional study
ConclusionThe diagnosis and management of dizziness remain a challenge for clinicians. Vertigo and light-headedness were the most common symptoms among different types of dizziness. Benign paroxysmal positional vertigo and stroke/transient ischemic attack were among the leading causes for common dizziness disorders. The prognosis of most dizzy patients was good.
Source: Brain and Behavior - December 30, 2022 Category: Neurology Authors: Youjin Shen, Wentao Liu, Xiaokun Qi Tags: ORIGINAL ARTICLE Source Type: research

Claude Syndrome in Childhood Associated with Probable Neuro-Behcet Disease
We present two children with Claude syndrome at 9 and 15 years of age. The typical clinical picture was consistent with brain magnetic resonance imaging findings. A thorough investigation regarding the underlying etiology revealed no definite diagnosis but clues suggestive of probable neuro-Behcet disease. Awareness of pediatric neurologists on arterial ischemic stroke has been increasing over the past decades, enabling timely diagnosis and appropriate management of rare childhood cases with midbrain stroke. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of conte...
Source: Neuropediatrics - December 23, 2022 Category: Neurology Authors: Yavuz, Pinar Solmaz, Ismail Kaya, Ummusen Akca Akgoz, Ayca Oguz, Kader K. Aytac, Selin Ozen, Seza Yalnizoglu, Dilek Tags: Short Communications Source Type: research

Case report: Two unique nonsense mutations in HTRA1-related cerebral small vessel disease in a Chinese population and literature review
ConclusionThis case report expands the clinical, radiographic, and genetic spectrum of HTRA1-CSVD. Attention should be paid to young patients with ischemic stroke as the first clinical manifestation. Genetic screening for such sporadic CSVD is recommended, even if the symptoms are atypical.
Source: Frontiers in Neurology - December 22, 2022 Category: Neurology Source Type: research

Transient global amnesia - hippocampal lesions in magnetic resonance imaging
Transient global amnesia is a benign syndrome characterized by a sudden onset loss of anterograde amnesia with full recovery. Magnetic resonance of the brain including diffusion –weighted imaging of patients with transient global amnesia revealed the presence of punctate hyperintense signal abnormalities in the hippocampus.
Source: Journal of Stroke and Cerebrovascular Diseases - December 22, 2022 Category: Neurology Authors: Aleksandra Golenia, Antoni Ferens, Anna Kolasa, Aleksandra Ignatiuk, Anna Kostera – Pruszczyk Source Type: research

Low NIHSS score large vessel occlusion caused by infective endocarditis treated with thrombectomy
A 24-year-old woman had undergone dental treatment 3 weeks before and had a mild fever for a week. She presented to the emergency department with the chief complaint of weakness in the right upper limb after waking up. She had mild paralysis of the right upper limb (National Institutes of Health Stroke Scale [NIHSS] score 1). Head magnetic resonance imaging (MRI) showed scattered infarcts in the left frontal and parietal lobes and left internal cerebral artery (ICA) occlusion (Fig. 1A, B). Cerebral angiography showed that the left ICA was occluded immediately after its origin (Fig.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2022 Category: Neurology Authors: So Matsukawa, Kohichi Go, Tao Yang, Takahisa Katsuki, Yohei Takenobu, Kenji Hashimoto Tags: Case Report Source Type: research

How to Avoid Misdiagnosing Spontaneous Cervical Spinal Epidural Hematoma as Ischemic Stroke: 3 Case Reports and Literature Review
We reported 3 SCEH patients who were initially suspected as IS in our center between Jun 2020 and April 2022 and analyzed their clinical characteristics together with 48 patients reported in the literature from Jan 1995 to April 2022. Two of the 3 SCEH patients had neck symptoms, while none of them presented cranial nerve symptoms. Cranial computed tomography (CT) scans were negative; however, abnormal signals in the cervical spinal canal were observed during cranial computed tomography angiography (CTA) and subsequent cervical CT confirmed the diagnosis of SCEH. All of them avoid mistreatment with recombinant tissue plasm...
Source: Cerebrovascular Diseases - December 14, 2022 Category: Neurology Source Type: research