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Total 2594 results found since Jan 2013.
Brain MRI correlations with disease burden and biomarkers in Fabry disease
ConclusionBrain MRI revealed progressive lacunar infarctions, white matter hyperintensities, and decreased brain volume in patients with Fabry disease. Brain MRI lesions were closely related to onset-age; disease duration, severity, burden; and plasma Lyso-Gb3. However, they were not associated with sex, α-galactosidase A activity, orGLA mutation type.
Source: Journal of Neurology - September 20, 2023 Category: Neurology Source Type: research
Pure Sensory Lacunar Infarction in the Thalamus Presented as Bilateral Hypogeusia: A Case Report
CONCLUSION: The exact gustatory pathway in humans remains uncertain nowadays. First, there were few reports about dysgeusia, which might be related to clinical neglect of taste deficits. Second, our knowledge of the human gustatory pathway depends solely on sporadic cases of taste-involved brain lesions. We reported a case of bilateral hypogeusia after right thalamic infarction. This finding indicates that, although there might be laterality of gustatory fibers to the left hemisphere, anatomical variations may exist in the human gustatory system. More research is needed to elucidate the understanding of the gustatory pathw...
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Yu-Chun Wang I-Hsu Chen Poyin Huang Source Type: research
Statins may Decrease Aneurysm wall Enhancement of Unruptured Fusiform Intracranial Aneurysms: A high-resolution 3T MRI Study
AbstractInflammation plays an integral role in the formation, growth, and progression to rupture of unruptured intracranial aneurysms. Aneurysm wall enhancement (AWE) in high-resolution magnetic resonance imaging (HR-MRI) has emerged as a surrogate biomarker of vessel wall inflammation and unruptured intracranial aneurysm instability. We investigated the correlation between anti-inflammatory drug use and three-dimensional AWE of fusiform intracranial aneurysms (FIAs). We retrospectively analyzed consecutive patients with FIAs in our database who underwent 3T HR-MRI at three Chinese centers. FIAs were classified as fusiform...
Source: Translational Stroke Research - September 7, 2023 Category: Neurology Source Type: research
Iatrogenic Air Embolisms During Endovascular Interventions: Impact of Origin and Number of Air Bubbles on Cerebral Infarctions
ConclusionIatrogenic AEs originating at the ascending aorta cause a similar number and pattern of cerebral infarctions compared to those with origin at the carotid artery. These findings underline the relevance and potential risk of AE occurring during endovascular interventions at the aortic valve and ascending aorta.
Source: Clinical Neuroradiology - September 4, 2023 Category: Neurology Source Type: research
A right convergence area of the prefrontal lobe is involved in the improvement of semantic fluency in patients with post-stroke aphasia
CONCLUSION: The improvement of semantic fluency in subacute PSA patients may require the participation of the right convergence area of the prefrontal lobe.PMID:37651207 | DOI:10.1080/10749357.2023.2253632
Source: Topics in Stroke Rehabilitation - August 31, 2023 Category: Neurology Authors: Tao Feng Chao Zhang Siwei Xu Lingmin Wang Kai Xu Zhiyuan Xie Jie Xiang Weiwei Chen Source Type: research
Lower 25-hydroxyvitamin D is associated with severer white matter hyperintensity and cognitive function in patients with non-disabling ischemic cerebrovascular events
Vascular cognitive impairment (VCI) is the second most common type of cognitive impairment, referring to the entire spectrum of cognitive impairment contributed by cerebrovascular pathology1. Due to the progressively higher incidence of stroke and cerebrovascular diseases, VCI, including post-stroke cognitive impairment are the leading causes of disability epidemic worldwide2-3. White matter lesions, manifested as white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI) scans, are one of the most common pathological characteristics of VCI4.
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2023 Category: Neurology Authors: Zhengsheng Gu, Xu Sun, Chenghao Wu, Binghan Li, Jingjing Chen, Weisen Wang, Xin Gao, Yuhao Tan, Bin Li, Ge Yin, Yawen Xu, Chenrui Song, Bingying Du, Xiaoying Bi Source Type: research
Perivascular spaces mediate a relationship between diabetes and other cerebral small vessel disease markers in cerebrovascular and neurodegenerative diseases
Cerebral small vessel disease (SVD) is used to describe heterogeneous pathological changes in perforating arterioles, venules, and capillaries that supply blood to subcortical structures.1 These pathological changes manifest on magnetic resonance imaging (MRI) as quantifiable volumetric measures. Established markers of SVD identified on MRI include deep white matter hyperintensities (dWMH) and periventricular white matter hyperintensities (pWMH) of presumed vascular origin and lacunes, and MRI visible enlarged perivascular spaces (PVS) in the white matter (wmPVS) or basal ganglia (bgPVS).
Source: Journal of Stroke and Cerebrovascular Diseases - August 3, 2023 Category: Neurology Authors: Julia Zebarth, Radia Kamal, George Perlman, Michael Ouk, Lisa Y. Xiong, Di Yu, William Z. Lin, Joel Ramirez, Mario Masellis, Maged Goubran, Bradley J. MacIntosh, Sandra E. Black, Hugo Cogo-Moreira, Christopher J.M. Scott, Robert Bartha, Sean Symons, Seyye Source Type: research
Secondary neurodegeneration of ipsilateral substantia nigra in acute ischemic stroke
ConclusionsA better understanding of the secondary degeneration of the substantia nigra has the potentiality to offer a chance for neuroprotection in acute stroke, but further studies are needed.
Source: Neurological Sciences - August 1, 2023 Category: Neurology Source Type: research
