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Short-Term Exposure to Fine Particulate Matter and Risk of Ischemic Stroke Brief Report
Conclusions—These findings suggest that short-term exposure to PM2.5 within 1 day before onset is associated with the subsequent occurrence of ischemic stroke.
Source: Stroke - November 27, 2016 Category: Neurology Authors: Ryu Matsuo, Takehiro Michikawa, Kayo Ueda, Tetsuro Ago, Hiroshi Nitta, Takanari Kitazono, Masahiro Kamouchi Tags: Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Influenza vaccination and cardiovascular risk in patients with recent TIA and stroke
Conclusions: Influenza vaccination was not associated with reduced outcome events in patients with recent atherothrombotic ischemic stroke after considering all baseline characteristics (including concomitant medications) associated with influenza vaccination.
Source: Neurology - May 26, 2014 Category: Neurology Authors: Lavallee, P. C., Labreuche, J., Fox, K. M., Lavados, P., Mattle, H., Steg, P. G., Amarenco, P., On behalf of the PERFORM, OPTIC, and AMISTAD Investigators Tags: Stroke prevention, Viral infections, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Evaluating Clinical Effectiveness of Pneumococcal Vaccination in Preventing Stroke: The CAPAMIS Study, 3-Year Follow-up
This study assessed clinical effectiveness of PPV23 in preventing ischemic stroke in people older than 60 years.Methods: We conducted a population-based cohort study involving 27,204 individuals of 60 years or older in Tarragona, Spain, who were prospectively followed from December 01, 2008, until November 30, 2011. Outcomes were neuroimaging-confirmed ischemic stroke, 30-day mortality from stroke, and all-cause death. Pneumococcal vaccination effectiveness was evaluated by Cox regression analyses, estimating hazard ratios (HRs) adjusted for age, sex, comorbidities, and influenza vaccine status.Results: Cohort members were...
Source: Journal of Stroke and Cerebrovascular Diseases - March 21, 2014 Category: Neurology Authors: Angel Vila-Corcoles, Olga Ochoa-Gondar, Teresa Rodriguez-Blanco, Cinta de Diego-Cabanes, Eva Satue-Gracia, Angel Vila-Rovira, Cristina Torrente Fraga, EPIVAC Research Group Tags: Original Articles Source Type: research

Increased Plasma Matrix Metalloproteinase-9 Levels Contribute to Intracerebral Hemorrhage during Thrombolysis after Concomitant Stroke and Influenza Infection
Conclusion: Preexisting influenza A virus infection led to increased plasma MMP-9 and TIMP-1 levels in mice undergoing thrombolysis after induced stroke. MMP-9 levels closely correlated with intracerebral bleeding after thrombolysis during concomitant infection and stroke. Thus, our data indicate that thrombolysis may be dangerous during influenza infection. MMP-9 inhibitors might be considered to reduce the side effects of thrombolysis during concomitant infection and stroke.Cerebrovasc Dis Extra 2016;6:50-59
Source: Cerebrovascular Diseases Extra - August 24, 2016 Category: Neurology Source Type: research

Air pollution and humidity as triggering factors for stroke. Results of a 12-year analysis in the West Paris area.
CONCLUSIONS: This study suggests that short-term exposure to air pollution and a high level of humidity are associated with a significant excess relative risk of calls for suspected stroke. PMID: 31030900 [PubMed - as supplied by publisher]
Source: Revue Neurologique - May 1, 2019 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Cross-Reactivity as a Mechanism Linking Infections to Stroke
The relevance of infections as risk factor for cerebrovascular disease is being increasingly recognized. Nonetheless, the pathogenic link between the two entities remains poorly understood. Consistent with recent advances in medicine, the present work addresses the hypothesis that infection-induced immune responses may affect human proteins associated with stroke. Applying established procedures in bioinformatics, the pathogen antigens and the human proteins were searched for common sequences using pentapeptides as probes. The data reported demonstrate massive peptide sharing between infectious pathogens—such as Chlamydi...
Source: Frontiers in Neurology - May 13, 2019 Category: Neurology Source Type: research

Risk of Hemorrhagic Stroke in Patients With Coronavirus Disease 2019
To the Editor We read with interest the article by Merkler et al regarding the increased incidence of ischemic stroke in patients with coronavirus disease 2019 (COVID-19) compared with those with influenza. The authors also reported that 13% of patients with COVID-19 were receiving anticoagulation at the time of the stroke. Could the authors comment on the rate of anticoagulant use in patients with COVID-19 who did not have an ischemic stroke? This would also be helpful to assess the possibility that anticoagulation may have been protective.
Source: JAMA Neurology - March 8, 2021 Category: Neurology Source Type: research

A reversible stroke-like splenial lesion in viral encephalopathy.
CONCLUSION: Our case confirmed with previous findings that a reversible stroke-like splenial lesion could be seen in virus related encephalopathy and regarded as a good prognosis marker. Transient intramyelinic edema or inflammatory infiltrate is the possible mechanism and further studies enrolling more related cases will be needed to confirm our finding. PMID: 24030090 [PubMed - indexed for MEDLINE]
Source: Acta Neurologica Taiwanica - December 12, 2015 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Multiple Border-Zone Infarcts Triggered by Influenza A Virus Infection in a Patient With Cerebral Autosomal Dominant Arteriopathy Presenting With Subcortical Infarcts and Leukoencephalopathy
We report the case of a 41-year-old woman with CADASIL who developed multiple border-zone infarcts due to influenza A virus infection. The patient had no apparent history or episode of stroke or altered consciousness following the onset of respiratory symptoms, which were due to the influenza A infection.
Source: Journal of Stroke and Cerebrovascular Diseases - February 23, 2020 Category: Neurology Authors: Keisuke Mizutani, Keita Sakurai, Ikuko Mizuta, Toshiki Mizuno, Hiroyuki Yuasa Tags: Case Report Source Type: research

Risk of Ischemic Stroke in Patients With Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza
This cohort study compares the rate of ischemic stroke among patients with COVID-19 vs patients with influenza in 2 hospitals in New York City, New York.
Source: JAMA Neurology - July 2, 2020 Category: Neurology Source Type: research

Influenza-Like Illness is Associated with Increased Short-Term Risk of Cervical Artery Dissection
Non-traumatic Cervical Artery Dissection (CeAD) is a leading cause of ischemic stroke in the young. Influenza-like illnesses (ILI) trigger ischemic strokes. We hypothesized that influenza and ILI are associated with CeAD.
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2020 Category: Neurology Authors: Madeleine D. Hunter, Yeseon P. Moon, Eliza C. Miller, Erin R. Kulick, Amelia K. Boehme, Mitchell SV Elkind Source Type: research

Treatment of Post-Influenza Vaccination Induced Acute Disseminated Encephalomyelitis (ADEM) with Plasma Exchange - A Case Report (P4.036)
DISCUSSION:Influenza vaccination has been rarely linked to ADEM. Due to a low-incidence of the disease, there are no established treatment guidelines. Our patient did not respond to steroids but showed marked radiographic improvement with PE. PE should be considered for refractory ADEM after influenza vaccination.Disclosure: Dr. Chahil has nothing to disclose. Dr. Pillainayagam has nothing to disclose. Dr. Schulz has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Chahil, M., Pillainayagam, C., Schulz, P. Tags: General Neurology III Source Type: research

Influenza vaccination and cardiovascular risk in patients with recent TIA and stroke
Source: Neurology - December 29, 2014 Category: Neurology Authors: Rahman, B., Heywood, A., Moa, A., MacIntyre, C. R. Tags: WRITECLICK & amp;reg; EDITOR ' S CHOICE Source Type: research

Neurological injuries and extracorporeal membrane oxygenation: the challenge of the new ECMO era
We present a case series of six neurological injuries that occurred in 1 year during the ECMO run or after the ECMO weaning. In each case the neurological complication had a dramatic effect: ranging from brain death to prolonged ICU stay and long term disability. This case series has an informative impact for the multidisciplinary teams treating ECMO patients because of its heterogeneity in pathogenesis and clinical manifestation: cerebral hemorrhage, ischemic stroke due to cerebral fat embolism, acute disseminated encephalomyelitis due to H1N1 Influenza. In our ECMO hub we started strict neurological monitoring involving...
Source: Neurological Sciences - February 19, 2016 Category: Neurology Source Type: research

The association of adult vaccination with the risk of cerebrovascular ischemia: A systematic review and meta-analysis
There is mounting evidence supporting infection as an independent risk factor for ischemic stroke (IS), while preliminary data indicate that vaccination may prevent IS. We performed a systematic review and meta-analysis of available randomized clinical trials (RCTs) or prospective observational cohorts reporting associations of influenza vaccination (IV) and/or pneumococcal vaccination (PV) with IS. We identified a total of 12 studies (543,311 patients; 47.4% vaccinated). Vaccination was not related to the risk of IS (RR=1.06, 95%CI: 0.74 –1.51, p=0.77), with no significant differences (p=0.26) among RCTs (RR=0.66, 95%CI...
Source: Journal of the Neurological Sciences - January 8, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Aristeidis H. Katsanos, Ramin Zand, Muhammad Fawad Ishfaq, Muhammad Taimur Malik, Theodore Karapanayiotides, Konstantinos Voumvourakis, Sotirios Tsiodras, John Parissis Source Type: research

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